LOCUS       NM_009429                956 bp    mRNA    linear   ROD 27-SEP-2023
DEFINITION  Mus musculus tumor protein, translationally-controlled 1 (Tpt1),
            mRNA.
ACCESSION   NM_009429
VERSION     NM_009429.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Morimoto Y, Tokumitsu A, Sone T, Hirota Y, Tamura R, Sakamoto A,
            Nakajima K, Toda M, Kawakami Y, Okano H and Ohta S.
  TITLE     TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and
            Brain Tumor Initiating Cells Regulated by Macrophage Migration
            Inhibitory Factor (MIF)
  JOURNAL   Neurochem Res 47 (9), 2741-2756 (2022)
   PUBMED   35622214
  REMARK    GeneRIF: TPT1 Supports Proliferation of Neural Stem/Progenitor
            Cells and Brain Tumor Initiating Cells Regulated by Macrophage
            Migration Inhibitory Factor (MIF).
REFERENCE   2  (bases 1 to 956)
  AUTHORS   Giri J, Basu M, Roy S, Mishra T, Jana K, Chande A and Ukil A.
  TITLE     Translationally Controlled Tumor Protein-Mediated Stabilization of
            Host Antiapoptotic Protein MCL-1 Is Critical for Establishment of
            Infection by Intramacrophage Parasite Leishmania donovani
  JOURNAL   J Immunol 208 (11), 2540-2548 (2022)
   PUBMED   35562118
  REMARK    GeneRIF: Translationally Controlled Tumor Protein-Mediated
            Stabilization of Host Antiapoptotic Protein MCL-1 Is Critical for
            Establishment of Infection by Intramacrophage Parasite Leishmania
            donovani.
REFERENCE   3  (bases 1 to 956)
  AUTHORS   Jeon HJ, Kang M, Kim JS and Oh JS.
  TITLE     TCTP overexpression reverses age-associated telomere attrition by
            upregulating telomerase activity in mouse oocytes
  JOURNAL   J Cell Physiol 237 (1), 833-845 (2022)
   PUBMED   34407217
  REMARK    GeneRIF: TCTP overexpression reverses age-associated telomere
            attrition by upregulating telomerase activity in mouse oocytes.
REFERENCE   4  (bases 1 to 956)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 956)
  AUTHORS   Jeon Y, Choi JY, Jang EH, Seong JK and Lee K.
  TITLE     Overexpression of translationally controlled tumor protein
            ameliorates metabolic imbalance and increases energy expenditure in
            mice
  JOURNAL   Int J Obes (Lond) 45 (7), 1576-1587 (2021)
   PUBMED   33931746
  REMARK    GeneRIF: Overexpression of translationally controlled tumor protein
            ameliorates metabolic imbalance and increases energy expenditure in
            mice.
REFERENCE   6  (bases 1 to 956)
  AUTHORS   Gachet Y, Tournier S, Lee M, Lazaris-Karatzas A, Poulton T and
            Bommer UA.
  TITLE     The growth-related, translationally controlled protein P23 has
            properties of a tubulin binding protein and associates transiently
            with microtubules during the cell cycle
  JOURNAL   J Cell Sci 112 (Pt 8), 1257-1271 (1999)
   PUBMED   10085260
REFERENCE   7  (bases 1 to 956)
  AUTHORS   Zoidl G, Blanchard AD, Zoidl C, Dong Z, Brennan A, Parmantier E,
            Mirsky R and Jessen KR.
  TITLE     Identification of transcriptionally regulated mRNAs from mouse
            Schwann cell precursors using modified RNA fingerprinting methods
  JOURNAL   J Neurosci Res 49 (1), 32-42 (1997)
   PUBMED   9211987
REFERENCE   8  (bases 1 to 956)
  AUTHORS   Lin MY, Munshi IA and Ouellette AJ.
  TITLE     The defensin-related murine CRS1C gene: expression in Paneth cells
            and linkage to Defcr, the cryptdin locus
  JOURNAL   Genomics 14 (2), 363-368 (1992)
   PUBMED   1427853
REFERENCE   9  (bases 1 to 956)
  AUTHORS   Bohm H, Benndorf R, Gaestel M, Gross B, Nurnberg P, Kraft R, Otto A
            and Bielka H.
  TITLE     The growth-related protein P23 of the Ehrlich ascites tumor:
            translational control, cloning and primary structure
  JOURNAL   Biochem Int 19 (2), 277-286 (1989)
   PUBMED   2479380
REFERENCE   10 (bases 1 to 956)
  AUTHORS   Chitpatima ST, Makrides S, Bandyopadhyay R and Brawerman G.
  TITLE     Nucleotide sequence of a major messenger RNA for a 21 kilodalton
            polypeptide that is under translational control in mouse tumor
            cells
  JOURNAL   Nucleic Acids Res 16 (5), 2350 (1988)
   PUBMED   3357792
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ063333.1, AK166584.1 and AA269935.1.
            
            [WARNING] On Sep 29, 2023 this sequence was replaced by
            NM_009429.4.
            
            On Dec 10, 2009 this sequence version replaced NM_009429.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI251570.1, BC092381.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                CJ063333.1         2-73
            73-888              AK166584.1         2-817
            889-956             AA269935.1         309-376
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.29 cM"
     gene            1..956
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /note="tumor protein, translationally-controlled 1"
                     /db_xref="GeneID:22070"
                     /db_xref="MGI:MGI:104890"
     exon            1..201
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..692
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /note="translationally regulated transcript (21 kDa);
                     fortilin; 21 kDa polypeptide under translational control"
                     /codon_start=1
                     /product="translationally-controlled tumor protein"
                     /protein_id="NP_033455.1"
                     /db_xref="CCDS:CCDS36980.1"
                     /db_xref="GeneID:22070"
                     /db_xref="MGI:MGI:104890"
                     /translation="MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAID
                     DSLIGGNASAEGPEGEGTESTVVTGVDIVMNHHLQETSFTKEAYKKYIKDYMKSLKGK
                     LEEQKPERVKPFMTGAAEQIKHILANFNNYQFFIGENMNPDGMVALLDYREDGVTPFM
                     IFFKDGLEMEKC"
     exon            202..275
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
     exon            276..466
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
     exon            467..572
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
     exon            573..689
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
     exon            690..894
                     /gene="Tpt1"
                     /gene_synonym="p21; p23; TCTP; Trt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttccgggg gagccgcgga cggtgacgta gccgagcgtg ccctctatat gaggttgggg
       61 agcgcccgcg tcggcctttt ccgcccgctc ccccctcccc ccgcgcgccg ctccggctgc
      121 accgcgctcg cttccgcgct gtcaggctag cgccgccgtc cccagccgtc accatgatca
      181 tctaccggga cctcatcagc catgacgagc tgttctccga catctacaag atccgggaga
      241 tcgcggacgg gctgtgcctg gaggtggagg gcaagatggt cagtagaaca gagggtgcca
      301 tcgatgactc gctcatcggt ggaaatgctt ccgctgaagg tccggagggc gaaggtaccg
      361 aaagcacagt agtcaccggt gttgacattg tcatgaacca tcacttacaa gaaaccagct
      421 tcacaaaaga ggcttacaaa aagtacatca aagactacat gaaatcactc aaaggcaaac
      481 ttgaagagca gaaaccagaa agagtaaagc cttttatgac tggagctgca gagcagatta
      541 agcacatcct tgctaatttc aataactacc agttttttat tggtgaaaac atgaatccag
      601 atggtatggt tgctctcctg gactaccgtg aagatggtgt gactccattc atgattttct
      661 ttaaggatgg cttagagatg gagaaatgtt aacaaattgg atctatcacc tgtcaccata
      721 attggctgct gcttaccatc catacaacac caggacttag gacaaatggg actgatgtca
      781 tcttgagctt ttattttgac cgtgatttat ttggagtggt ggcattgttt ttttaaggaa
      841 aaaaaacatg tcatgtgggt tgtctaaaaa taaagtgcat ttaaatccac ttaaaaaaaa
      901 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
