LOCUS       NM_026388               1756 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus transformation related protein 63 regulated 1 like
            (Tprg1l), transcript variant 1, mRNA.
ACCESSION   NM_026388
VERSION     NM_026388.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1756)
  AUTHORS   Pofantis,E., Neher,E. and Dresbach,T.
  TITLE     Regulation of a subset of release-ready vesicles by the presynaptic
            protein Mover
  JOURNAL   Proc Natl Acad Sci U S A 118 (3) (2021)
   PUBMED   33431696
  REMARK    GeneRIF: Regulation of a subset of release-ready vesicles by the
            presynaptic protein Mover.
REFERENCE   2  (bases 1 to 1756)
  AUTHORS   Akula,A.K., Zhang,X., Viotti,J.S., Nestvogel,D., Rhee,J.S.,
            Ebrecht,R., Reim,K., Wouters,F., Liepold,T., Jahn,O., Bogeski,I.
            and Dresbach,T.
  TITLE     The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover
            Is Required for Homomeric Interaction and Presynaptic Targeting
  JOURNAL   Front Mol Neurosci 12, 249 (2019)
   PUBMED   31787876
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1756)
  AUTHORS   Antonini,D., Dentice,M., Mahtani,P., De Rosa,L., Della Gatta,G.,
            Mandinova,A., Salvatore,D., Stupka,E. and Missero,C.
  TITLE     Tprg, a gene predominantly expressed in skin, is a direct target of
            the transcription factor p63
  JOURNAL   J Invest Dermatol 128 (7), 1676-1685 (2008)
   PUBMED   18256694
  REMARK    GeneRIF: Tprgl is a ubiquitously expressed gene located upstream of
            the p73 gene. Its encoded protein displays 44% amino acid identity
            with the protein encoded by Tprg, a p63 target gene that is located
            upstream of the p63 gene.
REFERENCE   4  (bases 1 to 1756)
  AUTHORS   Kremer,T., Kempf,C., Wittenmayer,N., Nawrotzki,R., Kuner,T.,
            Kirsch,J. and Dresbach,T.
  TITLE     Mover is a novel vertebrate-specific presynaptic protein with
            differential distribution at subsets of CNS synapses
  JOURNAL   FEBS Lett 581 (24), 4727-4733 (2007)
   PUBMED   17869247
  REMARK    GeneRIF: mover may act in concert with generally expressed
            scaffolding proteins in distinct sets of presynaptic terminals
REFERENCE   5  (bases 1 to 1756)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   6  (bases 1 to 1756)
  AUTHORS   Burre,J., Beckhaus,T., Schagger,H., Corvey,C., Hofmann,S.,
            Karas,M., Zimmermann,H. and Volknandt,W.
  TITLE     Analysis of the synaptic vesicle proteome using three gel-based
            protein separation techniques
  JOURNAL   Proteomics 6 (23), 6250-6262 (2006)
   PUBMED   17080482
REFERENCE   7  (bases 1 to 1756)
  AUTHORS   Burre,J., Beckhaus,T., Corvey,C., Karas,M., Zimmermann,H. and
            Volknandt,W.
  TITLE     Synaptic vesicle proteins under conditions of rest and activation:
            analysis by 2-D difference gel electrophoresis
  JOURNAL   Electrophoresis 27 (17), 3488-3496 (2006)
   PUBMED   16944461
REFERENCE   8  (bases 1 to 1756)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY739996.1, AK004777.1, AK004324.1 and AI840915.1.
            
            On Aug 4, 2005 this sequence version replaced NM_026388.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019544.1, AK155413.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                BY739996.1         1-18
            19-873              AK004777.1         2-856
            874-907             AK004324.1         487-520
            908-1739            AK004777.1         889-1720
            1740-1756           AI840915.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1756
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 83.88 cM"
     gene            1..1756
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /note="transformation related protein 63 regulated 1 like"
                     /db_xref="GeneID:67808"
                     /db_xref="MGI:MGI:1915058"
     exon            1..330
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..856
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /note="synaptic vesicle associated protein of 30 kD;
                     mossy-fiber terminal-associated vertebrate-specific
                     presynaptic protein; transformation related protein 63
                     regulated like"
                     /codon_start=1
                     /product="tumor protein p63-regulated gene 1-like protein"
                     /protein_id="NP_080664.1"
                     /db_xref="CCDS:CCDS19011.1"
                     /db_xref="GeneID:67808"
                     /db_xref="MGI:MGI:1915058"
                     /translation="MLQLRDTVDSAGTSPTAVLAAGEDAGAGRPGAGTPLRQTLWPLN
                     VHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKER
                     LVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQ
                     WDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQ
                     KESPLPGQANTVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF"
     exon            331..507
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /inference="alignment:Splign:2.1.0"
     exon            508..661
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /inference="alignment:Splign:2.1.0"
     exon            662..1742
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1722..1727
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /note="hexamer: AGTAAA"
     polyA_site      1742
                     /gene="Tprg1l"
                     /gene_synonym="1200015A19Rik; mover; Svap30; Tprgl"
                     /note="major polyA site"
ORIGIN      
        1 ggccgggcgg acgccggggc ggcggccgtc ggtggaggct gccggtggcg gcgcgatgct
       61 gcagctgcgg gacacggtgg actcggcggg cacgagcccc acggcggtgc tggcggccgg
      121 cgaggacgcg ggtgcgggcc ggcctggggc gggcacaccg ctgcgccaga cgttgtggcc
      181 gctgaacgtc cacgacccta cacgccgcgc ccgcgtcaag gagtacttcg tgttccggcc
      241 cggcaccatc gagcaggcgg tcgaggagat ccgcgccgtg gtacggcccg tggaggacgg
      301 cgagatccag ggggtgtggc tgctgaccga ggtggaccac tggaacaacg agaaggagcg
      361 gctggtgctg gtcaccgacc agtcgctgct catctgcaaa tatgacttca tcagccttca
      421 gtgccagcag gtggtcaggg tggcgctcag cgcggtagac accatctcct gtggagaatt
      481 ccagtttcct ccgaagtcgc tcaacaagag agaaggcttt ggggttcgca ttcagtggga
      541 caagcagagc cgcccttcct tcatcaacag atggaacccc tggtctacaa acatgcccta
      601 tgccaccttc atagaacacc caatggctgg catggacgag aagacagcgt ctctgtgcca
      661 tttggaaagc ttcaaggctc tcctgatcca agctgtcaag aaggcccaga aggagagccc
      721 actgccaggg caggcgaata ccgtgctggt gctggagcgc cccctcctca tcgagaccta
      781 cgtggggctc atgtccttca tcaacaatga agccaagctg ggctactcca tgaccagggg
      841 caagataggc ttctagacag ctgcgtcccg gaaaccaagg tggtggggac tccctgtgcc
      901 acctcatgcc acccactggc tggagggaag gagggcatgt atccgattag aatagtcaag
      961 tggattatgt atatttagtt ggatattgga catcttggca acacaatctt acaaaggcag
     1021 attcagctgc ccccatacca ctgtgttcct tctgtaacgc cacgttctcc ctccagcatg
     1081 ccgagcacaa tgtccaccca cttgtgctgt gtagactgtt gcatacagct gagtacagtg
     1141 agcggcttct gcacatattt aactctccct atatattaac tctcaagtgc tgtattttaa
     1201 aattcagccc gttttttaaa aaagctaaat acagtagcag ccagcagcca gtcactaaga
     1261 aagacagtct gcctggcagc tcctggtgaa cctgcctttc tgtgaatgtg tctgacttag
     1321 aatcacactt tataaattaa tccaggttgt gttaatacag cagttttcct aggcccaaaa
     1381 ggttactctc ataacataag ctagcccctt ccggaagtca tggtggtggg tttctatcat
     1441 cctgtctctg tttaaaaggg actgaatagt tgggttttaa aagtgcatgc tataaacaga
     1501 cgagcatcct agagctcact gagcactgct gagctttgac acgccagcca cacacagctt
     1561 gctgctgtcg ttctagcctt gccagtgcac tgtagatgct ggcctgtcac tctatacctc
     1621 tcgctttagt taaccggcat ggatgtgacc ggaatgccat ggcctatcca agaggaaagg
     1681 tgacctcaga tgcacctgtt ttcagcctgt gcttttgttc tagtaaagac atttaaacca
     1741 aaaaaaaaaa aaaaaa
//
