LOCUS       NM_175165               1084 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transformation related protein 63 regulated 1 (Tprg1),
            mRNA.
ACCESSION   NM_175165
VERSION     NM_175165.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1084)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1084)
  AUTHORS   Antonini,D., Dentice,M., Mahtani,P., De Rosa,L., Della Gatta,G.,
            Mandinova,A., Salvatore,D., Stupka,E. and Missero,C.
  TITLE     Tprg, a gene predominantly expressed in skin, is a direct target of
            the transcription factor p63
  JOURNAL   J Invest Dermatol 128 (7), 1676-1685 (2008)
   PUBMED   18256694
  REMARK    GeneRIF: Tprg gene is predominantly expressed in skin, is
            physically associated with the p63 gene during evolution, and
            directly regulated by p63 through a long-distance enhancer located
            within the Tprg locus.
            GeneRIF: The Tprg gene is predominantly expressed in keratinocytes,
            is physically associated with the p63 gene during evolution, and is
            directly regulated by p63 through a long-distance enhancer located
            within the Tprg locus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK036796.1.
            
            On Apr 6, 2007 this sequence version replaced NM_175165.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036796.1, SRR5189673.145515.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1084              AK036796.1         4-1087
FEATURES             Location/Qualifiers
     source          1..1084
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 17.0 cM"
     gene            1..1084
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /note="transformation related protein 63 regulated 1"
                     /db_xref="GeneID:71338"
                     /db_xref="MGI:MGI:1918588"
     exon            1..206
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
     exon            207..437
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..1055
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /codon_start=1
                     /product="tumor protein p63-regulated gene 1 protein"
                     /protein_id="NP_780374.1"
                     /db_xref="CCDS:CCDS28084.1"
                     /db_xref="GeneID:71338"
                     /db_xref="MGI:MGI:1918588"
                     /translation="MSTIGSFDGFQPVSLKQEEEDQPSENDHLSTKEGNSGKDPGSRR
                     ISRQQSITKATLYPNPYRQPYVSRKYFVTRPGAIETAVEDLKGHIAQTSGETVQGFWL
                     LTEIDHWNNEKEKILLLTDKTLLICKYDFIMLSCVQVQQVPLNAICCICLGKFVFPGM
                     SLDKRPGDGLRIFWGSTEGWSLLSRWNPWSTEVPYATFTEHPMKQTSEKFLEICKLSE
                     FTSKLVPAIENAHKNSAGSGSGKELVVLTQPILIETYTGLMSFIGNRNKLGYSLARGS
                     IGF"
     exon            438..529
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
     exon            530..706
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
     exon            707..860
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1084
                     /gene="Tprg1"
                     /gene_synonym="5430420C16Rik; Tprg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcactcaa ttttgcccct ttgagaggga gcggttacct ctcagctcag ctacagaagt
       61 gcggctgggt atcagtgggt gacagctcca ggctattctc ctgcccagcc tcctctgaga
      121 cagctacagt agccactgtt tgtggtctac ctccctttgt ctgggaagaa aaagaaaagc
      181 cttgaggacc cactactgcc ttccaggcta aagaaatgtc aacaattggg agctttgacg
      241 gattccagcc cgtgtctttg aagcaagagg aagaggacca accctctgaa aatgaccact
      301 tgtccacaaa ggaggggaat tcaggcaagg acccaggatc aaggaggatt tcaagacagc
      361 agagtataac taaagcgaca ctgtacccca atccttatcg ccagccctat gtttcacgga
      421 agtactttgt tacacggcca ggggccattg agactgctgt ggaagacttg aaaggccaca
      481 tagcacagac ttctggggag actgttcaag gcttctggct cctgacagag attgatcact
      541 ggaacaatga gaaggagaag atcctgctac tcacagacaa gaccctcttg atctgcaaat
      601 acgacttcat catgctcagc tgtgtgcagg tgcagcaggt tcccctgaat gccatctgct
      661 gcatctgtct gggcaagttt gttttcccag ggatgtctct ggacaagaga ccaggagatg
      721 gcctaaggat tttctggggg agcaccgagg ggtggtctct actgtctcgt tggaacccgt
      781 ggtccactga agttccctat gccaccttca cagagcatcc tatgaaacag accagtgaga
      841 agttccttga gatctgcaag ttgtctgagt tcacctctaa gcttgttcca gccatcgaga
      901 atgcccacaa gaattctgct ggatctggaa gtggaaagga actggtggtg ttaacccaac
      961 ctatactgat tgagacctac acagggctca tgtcattcat tggaaaccgc aacaaacttg
     1021 gctattccct tgctcgtggg agtattggct tttgagactc tttgttataa aatatatcat
     1081 ctat
//
