LOCUS       NP_036036                369 aa            linear   ROD 13-JUN-2024
DEFINITION  transmembrane protein adipocyte-associated 1 isoform 1 [Mus
            musculus].
ACCESSION   NP_036036
VERSION     NP_036036.2
DBSOURCE    REFSEQ: accession NM_011906.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 369)
  AUTHORS   Aki,T., Funakoshi,T., Nishida-Kitayama,J. and Mizukami,Y.
  TITLE     TPRA40/GPR175 regulates early mouse embryogenesis through
            functional membrane transport by Sjogren's syndrome-associated
            protein NA14
  JOURNAL   J Cell Physiol 217 (1), 194-206 (2008)
   PUBMED   18459117
  REMARK    GeneRIF: the functional plasma membrane transport of TPRA40 that
            regulates cell division of mouse embryos is mediated by NA14.
REFERENCE   2  (residues 1 to 369)
  AUTHORS   Vadasz,C., Saito,M., Gyetvai,B.M., Oros,M., Szakall,I.,
            Kovacs,K.M., Prasad,V.V., Morahan,G. and Toth,R.
  TITLE     Mapping of QTLs for oral alcohol self-administration in B6.C and
            B6.I quasi-congenic RQI strains
  JOURNAL   Neurochem Res 32 (7), 1099-1112 (2007)
   PUBMED   17273929
REFERENCE   3  (residues 1 to 369)
  AUTHORS   Desai,J., Shannon,M.E., Johnson,M.D., Ruff,D.W., Hughes,L.A.,
            Kerley,M.K., Carpenter,D.A., Johnson,D.K., Rinchik,E.M. and
            Culiat,C.T.
  TITLE     Nell1-deficient mice have reduced expression of extracellular
            matrix proteins causing cranial and vertebral defects
  JOURNAL   Hum Mol Genet 15 (8), 1329-1341 (2006)
   PUBMED   16537572
REFERENCE   4  (residues 1 to 369)
  AUTHORS   van der Zwaag,B., Burbach,J.P., Scharfe,C., Oefner,P.J.,
            Brunner,H.G., Padberg,G.W. and van Bokhoven,H.
  TITLE     Identifying new candidate genes for hereditary facial paresis on
            chromosome 3q21-q22 by RNA in situ hybridization in mouse
  JOURNAL   Genomics 86 (1), 55-67 (2005)
   PUBMED   15953540
REFERENCE   5  (residues 1 to 369)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   6  (residues 1 to 369)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
REFERENCE   7  (residues 1 to 369)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (residues 1 to 369)
  AUTHORS   Yang,H., Egan,J.M., Rodgers,B.D., Bernier,M. and
            Montrose-Rafizadeh,C.
  TITLE     Differential expression of a novel seven transmembrane domain
            protein in epididymal fat from aged and diabetic mice
  JOURNAL   Endocrinology 140 (6), 2859-2867 (1999)
   PUBMED   10342878
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153923.4.
            
            On Sep 14, 2006 this sequence version replaced NP_036036.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057296.1, AK172045.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 39.65 cM"
     Protein         1..369
                     /product="transmembrane protein adipocyte-associated 1
                     isoform 1"
                     /note="G protein-coupled receptor 175; transmembrane
                     protein adipocyte-associated 1; integral membrane protein
                     GPR175; transmembrane domain protein of 40 kDa regulated
                     in adipocytes; transmembrane domain protein regulated in
                     adipocytes 40 kDa"
                     /calculated_mol_wt=40447
     Site            20
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q99MU1.1)"
     Region          38..309
                     /region_name="Tmemb_40"
                     /note="Predicted membrane protein; pfam10160"
                     /db_xref="CDD:462970"
     Site            45..65
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            73..93
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            120..140
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            148..168
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            189..209
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            237..257
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            262..282
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU1.1)"
     Site            329
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q99MU1.1)"
     CDS             1..369
                     /gene="Tpra1"
                     /gene_synonym="40kDa; Gpr175; Tpra40"
                     /coded_by="NM_011906.3:371..1480"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS39555.1"
                     /db_xref="GeneID:24100"
                     /db_xref="MGI:MGI:1345190"
ORIGIN      
        1 maslqeangs tawppptasn isephqclll lyedigssrv rywdllllip nvlffifllw
       61 klplarakir vtsspifitf yilvfvvalv giaravvsmt vsasdaatva dkilweitrf
      121 fllaielsvi ilglafghle skssikrvla ittvlslays vtqgtleily pdshlsaedf
      181 niyghggrqf wlvsscfffl vyslvvilpk tplkervslp srrsfyvyag ilatlnllqg
      241 lgsallcani ivglccvdat tflyfsffap liyvaflrgf fgsepkilfs ykcqvdeaee
      301 pdmhlpqpya varregiesa gpacasaany sstqfdsagv aylddiasmp chtgsinstd
      361 serwkaina
//
