LOCUS       XM_036152912            4878 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus tryptophan hydroxylase 1 (Tph1), transcript
            variant X1, mRNA.
ACCESSION   XM_036152912
VERSION     XM_036152912.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000073.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4878
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
     gene            1..4878
                     /gene="Tph1"
                     /gene_synonym="Tph"
                     /note="tryptophan hydroxylase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 7
                     mRNAs, 62 ESTs, 18 long SRA reads, 19 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 2 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:21990"
                     /db_xref="MGI:MGI:98796"
     CDS             750..2093
                     /gene="Tph1"
                     /gene_synonym="Tph"
                     /codon_start=1
                     /product="tryptophan 5-hydroxylase 1 isoform X1"
                     /protein_id="XP_036008805.1"
                     /db_xref="GeneID:21990"
                     /db_xref="MGI:MGI:98796"
                     /translation="MIEDNKENKENKDHSSERGRVTLIFSLENEVGGLIKVLKIFQEN
                     HVSLLHIESRKSKQRNSEFEIFVDCDISREQLNDIFPLLKSHATVLSVDSPDQLTAKE
                     DVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKH
                     GDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNIPQLE
                     DVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHE
                     LLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFGLCKQDGQLRVFG
                     AGLLSSISELKHALSGHAKVKPFDPKIACKQECLITSFQDVYFVSESFEDAKEKMREF
                     AKTVKRPFGLKYNPYTQSVQVLRDTKSITSAMNELRYDLDVISDALARVTRWPSV"
ORIGIN      
        1 caaattgctc tgtgtgtgtt tgtgcgtgcg tgcacgagtg caagccaagg tttcaagaga
       61 ggccagaaga gggtgtcaga ttctctggtg catgagttac agctggctgt gaactgcctg
      121 atgtcggggc tggaaactaa actcaggccc aagaacagca agtgctctta tctgatgagc
      181 catcatccca gccccatgcc cagcagacat gggggctgtt aactgaaaca ttagaagtat
      241 gtccacgggc ctcccctttt ctgaagagaa aggggagagg aatgcatgga ggagagagaa
      301 ggcgtggagg aaggactgag aggagaggaa ggacgaaaaa ccgcagtctg gatgtaaaaa
      361 ctttttgtgg ctgaggatgc gtcaacatta acttaattaa aactctacga gaatagctgt
      421 gaatgagacc ggcgcctggg ttgcagagca gacagcagac agcgactaag aggtcagggc
      481 aagctgctcc cgcccacacc cgcgctgttc ccgccccctc ctcgccctcc tcccgcactg
      541 ctatatcctc aaccgtgcgc ccggcgccca ttggccgttc tgacgatgcg cttctcctat
      601 aagaggcgtc agctcccatc ctcaagtgac tctttaaact ccagtggctc tgaggtgagt
      661 gggtgagtgg gatagcccct ccctgggaca tcggatcaga agactcccag caaggacggg
      721 atcaacttct agtaggaacc agattcacca tgattgaaga caacaaggag aacaaagaga
      781 acaaagacca ttcctccgaa agagggagag tgactctcat cttctccttg gagaatgaag
      841 tcggaggact cataaaagtg ctgaaaatct tccaggagaa tcatgtgagc ctgttacaca
      901 tcgagtcccg gaaatcaaag caaagaaatt cagaatttga gatatttgtt gactgcgaca
      961 tcagccgaga acagttgaat gacatcttcc ccctgctgaa gtcgcacgcc accgtcctct
     1021 cggtggactc gcccgatcag ctcactgcga aggaagacgt tatggagact gtcccttggt
     1081 ttccaaagaa gatttctgac ctggacttct gcgccaacag agtgctgttg tatggatccg
     1141 aacttgacgc cgaccaccct ggcttcaaag acaatgtcta tcgtagaaga cgaaagtatt
     1201 ttgcagagtt ggctatgaac tacaaacatg gggaccccat tcccaagatt gaattcacgg
     1261 aagaagagat taagacctgg gggaccatct tccgagagct aaacaaactc tacccgaccc
     1321 acgcctgcag ggagtacctc agaaacctcc ctttgctctc aaaatactgt ggctatcggg
     1381 aagacaacat cccgcaactg gaggatgtct ccaacttttt aaaagaacgc actgggtttt
     1441 ccatccgtcc tgtggctggt tacctctcac cgagagattt tctgtcgggg ttagcctttc
     1501 gagtctttca ctgcactcag tatgtgagac acagttcaga tcccctctac actccagagc
     1561 cagacacctg ccatgaactc ctaggccacg ttcctctctt ggctgaaccc agttttgctc
     1621 aattctccca agaaattggc ctggcttccc ttggagcttc agaggagaca gttcaaaaac
     1681 tggcaacgtg ctactttttc actgtggagt ttgggctgtg caaacaagat ggacagctga
     1741 gagtctttgg ggccggcttg ctttcttcca tcagtgaact caaacatgca ctttctggac
     1801 atgccaaagt caagcccttt gatcccaaga ttgcctgtaa acaggaatgt ctcatcacga
     1861 gcttccagga tgtctacttt gtatctgaga gctttgaaga tgcaaaggag aagatgagag
     1921 aatttgccaa gaccgtgaag cgcccgtttg gactgaagta caacccgtac acacagagtg
     1981 ttcaggttct cagagacacc aagagcataa ctagtgccat gaatgagttg cggtatgacc
     2041 ttgatgtcat cagtgatgcc ctcgctaggg tcaccaggtg gcccagtgtg tgatggtttc
     2101 cagtgcatat ccaaaaagcc tttgagcatc agtctagagc cagggctagt tcttgcttcc
     2161 cctgaagacc tgcttgggga gggacagcag ctcccagctt agcaatgtct ctcgcctctc
     2221 tccatattca atcactcact ctctctgaaa atgcacacct ggaactgctt atcttctact
     2281 tctgttttgt cttctggaac ctgctgaggg aaatatagtt cacgtgccac gtgatgccca
     2341 ggacacacat ttaaaatatt ttatttcatt aaaatgtaat tgaatcattc tctcccttcc
     2401 ctttcttccc tccaacccct ccctctcaaa ttcatggcct ttctaccaaa tgcccgtctt
     2461 tgatgggtga gttgtctgac actggccaga gctggactca tggtgatgcc attttcccca
     2521 gcccatcatt agtggatggc ctctctggat gccacgatga atgtgtctgt tacctattac
     2581 tgactgtgtg acagcccagg cacagtcaca cactagactt caaggggact cgctgaaaca
     2641 gaagtgtgga tgactttgcg ctagagcatg gctagtaaag tgcaagctgg cttcaagtgc
     2701 tgtgtcagac agggacgtag aagccaccaa gactcagcca gtgctttctg gcactttgtt
     2761 tcaaggtgta accctaggat atagtgagaa ggtatgtgtg tgtgtgtggg gtggtgcaga
     2821 gggtaggaaa tggggatggg aatggagaag ggccaaaggg agcagtttgt atctgagact
     2881 gtacttatgc gagggagagc tgtgaggatt ggagcacatg tggtgtccgc ataagcagtt
     2941 gtataagctt ttcactactg taacaaagtg tcagggacaa tcagcttata cagagaaaag
     3001 gtttctcttg gatgctttgg tccattagaa gttgttcccg tggtttaagc cactggtgaa
     3061 gcaaggcatg ataggagaat gtgacagagc aaacttcata aagctataca cgtcataaag
     3121 gatggaaaga gaaagagtga aggattttag agaaggaaga agggagagag ggaaagagag
     3181 agggaggagg acacacacac acacacacac acacaaaggg ggtgagagag agagtcagag
     3241 acagagacag agacagaaag atcctacagt tcagtttaag agttcactac cagggtaaga
     3301 gagagggctc agcagttaag agtaccagct gttcttccag aggaccctgg tttgcttccc
     3361 agcatccaca ctgtggctta gaaccatctg taactctagt tccagaggat ccagtgtttt
     3421 ctggcctcca tagagagcag gcaggcatgc aagtggtaca cagatatgca tgcagcaaaa
     3481 acacccatac acatacaata aaaagtagaa gaccctacct ctgcttttcc cattaatagt
     3541 gaaattatat accattggac aggcttcatc tcaagcccac tagatatatt ttcacactag
     3601 atttttaaaa acacctttta aggattcaga ggaaactatt gaaagctgcg cttcacccca
     3661 tgctctacaa ggaagtgtaa tccagccgtc tcagatcttt agaaacatac ccactttaac
     3721 agctggtgag cacgcatccg tccgcaagta gatacgttag ctctgaaatc acctgaagta
     3781 caaaccagct agtttacagc ctgcttgatt accagggaaa gcactataaa gaaatcctac
     3841 cgacagcaaa cagagagtgc cgtctgctgt ttctggttat ttccactaga ctctggtggt
     3901 gctgaagaat cacttattgg ctttttaatt ggttgtgctc tgactaaagc actttaaact
     3961 gtaaagccac aaccttaccg tttgtaactt caggatagaa aaaataagcg aagggcttga
     4021 ctttgtctct gctctgcttc tgtgatattt ggcaagtcag ggttccaaga gccttggagt
     4081 cttcaaaaca cctaagaatc ttttaatagt tattcaaaca ccaggccaga ttcaaacaaa
     4141 aagcaaggct tgcaattctt tcctggagag ccattcctcg acagcagcag cgtgcttgac
     4201 tttttgaaga aaacacaaat gctaatcgtc agagtgcctg cgttccttaa tctcatgctt
     4261 tggcatttgg aattacataa gtagcaagat gcagcaaaat gcacagaatt attgctcatt
     4321 tttaagttgg cttctaaacc acagaaagaa gaaagccagg acttctcaaa agcactaaat
     4381 aactgagacc gtatgttcat ttccaggaag tggataaaaa gataacagtg gtccatttca
     4441 ctcttcatgt tacagtgcca catacactta taatttaaga atttgttcca ctgggtaata
     4501 aacttaaagt tcatgatctc aagaagtatt ttttttaaag cacatttaaa acttttattt
     4561 tatgtgtgtg ggccccagga atcaaactcc agttgtcagg cttggccaca agccccttta
     4621 tttgctgagc cagtttttgc caccccctcc cccaattctt ttaatcaaac acacattaaa
     4681 aacagtttca attttatgtt cacaatgtta taagttcaga gaccctagca gtgatgatgg
     4741 ttggtacaaa gaatcagcct tgggggttag acaaagtatg aacatgcctc aatggaaccc
     4801 attactttgt ataccacttt aaaatatttt tacaaaaaga aatcacaaaa tatacaataa
     4861 aaaatataca tcactcta
//
