LOCUS       XM_011250846            4161 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus tryptophan hydroxylase 1 (Tph1), transcript
            variant X2, mRNA.
ACCESSION   XM_011250846
VERSION     XM_011250846.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000073.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_011250846.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4161
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
     gene            1..4161
                     /gene="Tph1"
                     /gene_synonym="Tph"
                     /note="tryptophan hydroxylase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 43
                     ESTs, 18 long SRA reads, 4 Proteins, and 96% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:21990"
                     /db_xref="MGI:MGI:98796"
     CDS             350..1381
                     /gene="Tph1"
                     /gene_synonym="Tph"
                     /codon_start=1
                     /product="tryptophan 5-hydroxylase 1 isoform X2"
                     /protein_id="XP_011249148.1"
                     /db_xref="GeneID:21990"
                     /db_xref="MGI:MGI:98796"
                     /translation="METVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRR
                     KYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKY
                     CGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSD
                     PLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFG
                     LCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKIACKQECLITSFQDVYFVSE
                     SFEDAKEKMREFAKTVKRPFGLKYNPYTQSVQVLRDTKSITSAMNELRYDLDVISDAL
                     ARVTRWPSV"
ORIGIN      
        1 accatgattg aagacaacaa ggagaacaaa gagaacaaag accattcctc cgaaagaggg
       61 agagtgactc tcatcttctc cttggagaat gaagtcggag gactcataaa agtgctgaaa
      121 atcttccagg agaatcatgt gagcctgtta cacatcgagt cccggaaatc aaagcaaaga
      181 aattcagaat ttgagatatt tgttgactgc gacatcagcc gagaacagtt gaatgacatc
      241 ttccccctgc tgaagtcgca cgccaccgtc ctctcggtgg actcgcccga tcagctcact
      301 gcgaaggaag acggtacgtg tgagacggca aagccccacc tcgcagatta tggagactgt
      361 cccttggttt ccaaagaaga tttctgacct ggacttctgc gccaacagag tgctgttgta
      421 tggatccgaa cttgacgccg accaccctgg cttcaaagac aatgtctatc gtagaagacg
      481 aaagtatttt gcagagttgg ctatgaacta caaacatggg gaccccattc ccaagattga
      541 attcacggaa gaagagatta agacctgggg gaccatcttc cgagagctaa acaaactcta
      601 cccgacccac gcctgcaggg agtacctcag aaacctccct ttgctctcaa aatactgtgg
      661 ctatcgggaa gacaacatcc cgcaactgga ggatgtctcc aactttttaa aagaacgcac
      721 tgggttttcc atccgtcctg tggctggtta cctctcaccg agagattttc tgtcggggtt
      781 agcctttcga gtctttcact gcactcagta tgtgagacac agttcagatc ccctctacac
      841 tccagagcca gacacctgcc atgaactcct aggccacgtt cctctcttgg ctgaacccag
      901 ttttgctcaa ttctcccaag aaattggcct ggcttccctt ggagcttcag aggagacagt
      961 tcaaaaactg gcaacgtgct actttttcac tgtggagttt gggctgtgca aacaagatgg
     1021 acagctgaga gtctttgggg ccggcttgct ttcttccatc agtgaactca aacatgcact
     1081 ttctggacat gccaaagtca agccctttga tcccaagatt gcctgtaaac aggaatgtct
     1141 catcacgagc ttccaggatg tctactttgt atctgagagc tttgaagatg caaaggagaa
     1201 gatgagagaa tttgccaaga ccgtgaagcg cccgtttgga ctgaagtaca acccgtacac
     1261 acagagtgtt caggttctca gagacaccaa gagcataact agtgccatga atgagttgcg
     1321 gtatgacctt gatgtcatca gtgatgccct cgctagggtc accaggtggc ccagtgtgtg
     1381 atggtttcca gtgcatatcc aaaaagcctt tgagcatcag tctagagcca gggctagttc
     1441 ttgcttcccc tgaagacctg cttggggagg gacagcagct cccagcttag caatgtctct
     1501 cgcctctctc catattcaat cactcactct ctctgaaaat gcacacctgg aactgcttat
     1561 cttctacttc tgttttgtct tctggaacct gctgagggaa atatagttca cgtgccacgt
     1621 gatgcccagg acacacattt aaaatatttt atttcattaa aatgtaattg aatcattctc
     1681 tcccttccct ttcttccctc caacccctcc ctctcaaatt catggccttt ctaccaaatg
     1741 cccgtctttg atgggtgagt tgtctgacac tggccagagc tggactcatg gtgatgccat
     1801 tttccccagc ccatcattag tggatggcct ctctggatgc cacgatgaat gtgtctgtta
     1861 cctattactg actgtgtgac agcccaggca cagtcacaca ctagacttca aggggactcg
     1921 ctgaaacaga agtgtggatg actttgcgct agagcatggc tagtaaagtg caagctggct
     1981 tcaagtgctg tgtcagacag ggacgtagaa gccaccaaga ctcagccagt gctttctggc
     2041 actttgtttc aaggtgtaac cctaggatat agtgagaagg tatgtgtgtg tgtgtggggt
     2101 ggtgcagagg gtaggaaatg gggatgggaa tggagaaggg ccaaagggag cagtttgtat
     2161 ctgagactgt acttatgcga gggagagctg tgaggattgg agcacatgtg gtgtccgcat
     2221 aagcagttgt ataagctttt cactactgta acaaagtgtc agggacaatc agcttataca
     2281 gagaaaaggt ttctcttgga tgctttggtc cattagaagt tgttcccgtg gtttaagcca
     2341 ctggtgaagc aaggcatgat aggagaatgt gacagagcaa acttcataaa gctatacacg
     2401 tcataaagga tggaaagaga aagagtgaag gattttagag aaggaagaag ggagagaggg
     2461 aaagagagag ggaggaggac acacacacac acacacacac acaaaggggg tgagagagag
     2521 agtcagagac agagacagag acagaaagat cctacagttc agtttaagag ttcactacca
     2581 gggtaagaga gagggctcag cagttaagag taccagctgt tcttccagag gaccctggtt
     2641 tgcttcccag catccacact gtggcttaga accatctgta actctagttc cagaggatcc
     2701 agtgttttct ggcctccata gagagcaggc aggcatgcaa gtggtacaca gatatgcatg
     2761 cagcaaaaac acccatacac atacaataaa aagtagaaga ccctacctct gcttttccca
     2821 ttaatagtga aattatatac cattggacag gcttcatctc aagcccacta gatatatttt
     2881 cacactagat ttttaaaaac accttttaag gattcagagg aaactattga aagctgcgct
     2941 tcaccccatg ctctacaagg aagtgtaatc cagccgtctc agatctttag aaacataccc
     3001 actttaacag ctggtgagca cgcatccgtc cgcaagtaga tacgttagct ctgaaatcac
     3061 ctgaagtaca aaccagctag tttacagcct gcttgattac cagggaaagc actataaaga
     3121 aatcctaccg acagcaaaca gagagtgccg tctgctgttt ctggttattt ccactagact
     3181 ctggtggtgc tgaagaatca cttattggct ttttaattgg ttgtgctctg actaaagcac
     3241 tttaaactgt aaagccacaa ccttaccgtt tgtaacttca ggatagaaaa aataagcgaa
     3301 gggcttgact ttgtctctgc tctgcttctg tgatatttgg caagtcaggg ttccaagagc
     3361 cttggagtct tcaaaacacc taagaatctt ttaatagtta ttcaaacacc aggccagatt
     3421 caaacaaaaa gcaaggcttg caattctttc ctggagagcc attcctcgac agcagcagcg
     3481 tgcttgactt tttgaagaaa acacaaatgc taatcgtcag agtgcctgcg ttccttaatc
     3541 tcatgctttg gcatttggaa ttacataagt agcaagatgc agcaaaatgc acagaattat
     3601 tgctcatttt taagttggct tctaaaccac agaaagaaga aagccaggac ttctcaaaag
     3661 cactaaataa ctgagaccgt atgttcattt ccaggaagtg gataaaaaga taacagtggt
     3721 ccatttcact cttcatgtta cagtgccaca tacacttata atttaagaat ttgttccact
     3781 gggtaataaa cttaaagttc atgatctcaa gaagtatttt ttttaaagca catttaaaac
     3841 ttttatttta tgtgtgtggg ccccaggaat caaactccag ttgtcaggct tggccacaag
     3901 cccctttatt tgctgagcca gtttttgcca ccccctcccc caattctttt aatcaaacac
     3961 acattaaaaa cagtttcaat tttatgttca caatgttata agttcagaga ccctagcagt
     4021 gatgatggtt ggtacaaaga atcagccttg ggggttagac aaagtatgaa catgcctcaa
     4081 tggaacccat tactttgtat accactttaa aatattttta caaaaagaaa tcacaaaata
     4141 tacaataaaa aatatacatc a
//
