LOCUS       NM_001025262            5361 bp    mRNA    linear   ROD 08-FEB-2024
DEFINITION  Mus musculus tumor protein D52 (Tpd52), transcript variant 2, mRNA.
ACCESSION   NM_001025262
VERSION     NM_001025262.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5361)
  AUTHORS   Hooper,J.E., Feng,W., Li,H., Leach,S.M., Phang,T., Siska,C.,
            Jones,K.L., Spritz,R.A., Hunter,L.E. and Williams,T.
  TITLE     Systems biology of facial development: contributions of ectoderm
            and mesenchyme
  JOURNAL   Dev Biol 426 (1), 97-114 (2017)
   PUBMED   28363736
REFERENCE   2  (bases 1 to 5361)
  AUTHORS   Ito,C., Mukudai,Y., Itose,M., Kato,K., Motohashi,H., Shimane,T.,
            Kondo,S. and Shirota,T.
  TITLE     Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal
            Differentiation of Chondrocytes
  JOURNAL   Biomed Res Int 2017, 6014278 (2017)
   PUBMED   28798933
  REMARK    GeneRIF: the important roles of TPD52 and TPD54, which work
            oppositely, in the terminal differentiation of chondrocytes during
            endochondral ossification.
REFERENCE   3  (bases 1 to 5361)
  AUTHORS   Kamili,A., Roslan,N., Frost,S., Cantrill,L.C., Wang,D.,
            Della-Franca,A., Bright,R.K., Groblewski,G.E., Straub,B.K.,
            Hoy,A.J., Chen,Y. and Byrne,J.A.
  TITLE     TPD52 expression increases neutral lipid storage within cultured
            cells
  JOURNAL   J Cell Sci 128 (17), 3223-3238 (2015)
   PUBMED   26183179
  REMARK    GeneRIF: findings uncover a new isoform-specific role for TPD52 in
            promoting intracellular lipid storage, which might be relevant to
            TPD52 overexpression in cancer.
REFERENCE   4  (bases 1 to 5361)
  AUTHORS   Byrne,J.A., Frost,S., Chen,Y. and Bright,R.K.
  TITLE     Tumor protein D52 (TPD52) and cancer-oncogene understudy or
            understudied oncogene?
  JOURNAL   Tumour Biol 35 (8), 7369-7382 (2014)
   PUBMED   24798974
  REMARK    Review article
REFERENCE   5  (bases 1 to 5361)
  AUTHORS   Biesemann,C., Gronborg,M., Luquet,E., Wichert,S.P., Bernard,V.,
            Bungers,S.R., Cooper,B., Varoqueaux,F., Li,L., Byrne,J.A.,
            Urlaub,H., Jahn,O., Brose,N. and Herzog,E.
  TITLE     Proteomic screening of glutamatergic mouse brain synaptosomes
            isolated by fluorescence activated sorting
  JOURNAL   EMBO J 33 (2), 157-170 (2014)
   PUBMED   24413018
REFERENCE   6  (bases 1 to 5361)
  AUTHORS   Lewis,J.D., Payton,L.A., Whitford,J.G., Byrne,J.A., Smith,D.I.,
            Yang,L. and Bright,R.K.
  TITLE     Induction of tumorigenesis and metastasis by the murine orthologue
            of tumor protein D52
  JOURNAL   Mol Cancer Res 5 (2), 133-144 (2007)
   PUBMED   17314271
  REMARK    GeneRIF: Together, these data suggest that mD52 expression in 3T3
            cells initiated cellular transformation, tumorigenesis, and
            progression to metastasis.
REFERENCE   7  (bases 1 to 5361)
  AUTHORS   Boutros,R., Fanayan,S., Shehata,M. and Byrne,J.A.
  TITLE     The tumor protein D52 family: many pieces, many puzzles
  JOURNAL   Biochem Biophys Res Commun 325 (4), 1115-1121 (2004)
   PUBMED   15555543
  REMARK    Review article
REFERENCE   8  (bases 1 to 5361)
  AUTHORS   Byrne,J.A., Nourse,C.R., Basset,P. and Gunning,P.
  TITLE     Identification of homo- and heteromeric interactions between
            members of the breast carcinoma-associated D52 protein family using
            the yeast two-hybrid system
  JOURNAL   Oncogene 16 (7), 873-881 (1998)
   PUBMED   9484778
REFERENCE   9  (bases 1 to 5361)
  AUTHORS   Byrne,J.A., Mattei,M.G. and Basset,P.
  TITLE     Definition of the tumor protein D52 (TPD52) gene family through
            cloning of D52 homologues in human (hD53) and mouse (mD52)
  JOURNAL   Genomics 35 (3), 523-532 (1996)
   PUBMED   8812487
REFERENCE   10 (bases 1 to 5361)
  AUTHORS   Byrne,J.A., Tomasetto,C., Garnier,J.M., Rouyer,N., Mattei,M.G.,
            Bellocq,J.P., Rio,M.C. and Basset,P.
  TITLE     A screening method to identify genes commonly overexpressed in
            carcinomas and the identification of a novel complementary DNA
            sequence
  JOURNAL   Cancer Res 55 (13), 2896-2903 (1995)
   PUBMED   7796418
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161056.5, AY048852.1, AK005456.1, AK032111.1 and AC133935.3.
            
            [WARNING] On Mar 20, 2024 this sequence was replaced by
            NM_001025262.3.
            
            On Oct 19, 2017 this sequence version replaced NM_001025262.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY048852.1, SRR9219381.100713.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC161056.5         198434-198533
            101-2293            AY048852.1         1-2193
            2294-2455           AK005456.1         2086-2247
            2456-3264           AK032111.1         2272-3080
            3265-5361           AC133935.3         12991-15087
FEATURES             Location/Qualifiers
     source          1..5361
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 2.23 cM"
     gene            1..5361
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /note="tumor protein D52"
                     /db_xref="GeneID:21985"
                     /db_xref="MGI:MGI:107749"
     exon            1..300
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
     exon            301..416
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
     exon            417..565
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
     exon            566..667
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
     exon            668..716
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
     exon            717..5361
                     /gene="Tpd52"
                     /gene_synonym="mD52"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggcggggc tttaagcccg gttcctctgg gccggagctg ggcggggctt taagcccggt
       61 tcctcttctc acctgggctg cacaggtcag ccggatctcc ctcagcccgg ggctcccagg
      121 ctgccgcagc gccatgctcg ccttgctcgc tgccttcagc tagcatggag tgcagagata
      181 tggagttggc tgatgattac caatccccct ttgattttga ttctggagtg aacaagaact
      241 acctctacct ctctccaagc gggaacacct cgccgcctgg ttcacctaca cagaacgttg
      301 gtctgctgaa gacagagccg gtggccgagg aaggagagga tgctgttacc atgctcagtg
      361 ctccagaggc gctgacggaa gaggagcaag aggagctgag gcgggagctt actaaggtgg
      421 aagaagaaat ccagactctg tcccaagtat tggccgcaaa agagaagcat ctcgccgagc
      481 tcaagcggaa gctcggcatc tcctcgcttc aggagttcaa gcagaacatt gccaaagggt
      541 ggcaagacgt gacggcaacc aatgcataca agaagacctc tgaaactcta tcgcaagctg
      601 ggcagaaggc ctccgctgca ttttcatcgg ttggctcagt catcaccaaa aagctggaag
      661 acgtgaaaaa ctccccaact ttcaagtcat ttgaagaaaa agttgaaaat ttaaagtcta
      721 aagtaggagg agccaagcct gctggcggcg attttggaga agtcctgaat tccacagcca
      781 acgctaccag taccatgacc acagagcctc ctccagaaca gatgacagag agcccctgag
      841 ctgccgacct gtgtcctgct gcccactgcc aggtgctgcc ggcgagagcc aagtacatct
      901 tgacaacgct catggctgcg gatttccacc agatgtgctt ttatttagct ttacttattt
      961 ctttgaccaa atagttgatg aatgaaacaa agtgaaatca cttgacctcc actccaggga
     1021 aacactgtta gcatgcatgg aaggcccttt gtataggaaa cagcatcata gagcctctgg
     1081 tagatccctg caggcaacta ctgtgtttct ccttaaaatc actgtacatc tggattctag
     1141 tttgatcttt ctttactatc tacatgaatc attgtttttg ggtctctgta cacttaatca
     1201 atttctaaca aactgtcctt ttctaaattc tggttattaa aagtcttgga attatttcat
     1261 tcctttcaaa ggagaaacta ccagctacat tttttttctc ggataaacag ttctgtgagg
     1321 accatatctt gggtttctaa agacaccaga ctaaagtaga caggtgtgta tgcagttcta
     1381 tagttctgta aattaaaaac atgcagacac tcaaacttcc agtggggaga gtgtgggtcc
     1441 tgctcttgcc ttggtaactg tcatttgtag ctacatctat ttgagctcaa atatgcttat
     1501 cagttattta ttataccatt ctcacacatt tttttacaag attaaaattt aatttcaggt
     1561 aaattgagag aataacattg tgagttaagt atatgatatt acagtaagtt ggaatgttcc
     1621 cacattcatc actgataatt ccaaaagtct aaacgtcttt aggtctatac agttataaaa
     1681 atgctaaaaa aaattcacca taggggaaat tactgcctcc attaaatcca tttaacacct
     1741 ttaggaagga cagaaagttc tatgagaaat acaacttgaa tattttttat actaagggat
     1801 tgttgataac tccgaaagct gcgaggcgtt actatgactg agctgatcag gcagtttctg
     1861 ttctcagtgt gttagtgcct gagctgttct gtatgtagaa atcgttccca ctctaagaac
     1921 tgtcggggct gtgagtcaaa gcttcccagt ggctctgcta agcccctctg ttaactgtgg
     1981 tcactcctga ctcactcctg cttcctttgc tgtgtatgtt tatggcctat gaggttgtat
     2041 ctgttacttc tttctctatt gtggttttac cagtgtccat gccaaatgtt aactgccaag
     2101 cttggagtga cctaaagcct ttttcagagc atggctagat ttaattgagg ataaggtttc
     2161 tgcaaaccag aattgaaaag ccacagtgtc ggttgtcaca aaatgacatg ctgccattcc
     2221 tggttgctgc tcggatgcaa tggaaactat gcttgattac atgtgaaaat cttaataaag
     2281 tctgtgtctc agtagtatag gtttcaatat ttattaagag gacagtggtc tggacaaaac
     2341 ttgttatatt ctaaaatcaa ctggtattct ggaagcattt tcctagagga ctggaactgt
     2401 agaaatttgt ctctagagaa atattgtgat tatccaatat aatgattttt ctaccaatta
     2461 gtctttttat ttttcttctt cttcttcttg ctaacatctt gttaacagat tgtttcctgg
     2521 gtgcctactc tgtatttgta accaagcaaa aacagaataa gatggtagtt tttttgtttt
     2581 ttttaaataa gaaatcttca agttttgtat agagatttca tatgaggaaa atgattaagt
     2641 ggagagaagg agaaggaatg tacatagatc agaccaggga tgagtgtgga agaaactctt
     2701 cccacacttc atctagaaag ttaatctact ggaaggcacc ctgcctcatc aaagatgtta
     2761 caaaacgatg aaggactaac acagaaaatt aaatgggagt tttagaatat tcacatatat
     2821 ccagaatatc tgttggagat tcattgtgag ttagttcaca gatactgagg aaattacaga
     2881 cagctattaa cagaaatgta gcagaaaggt tggggctgct tactgggatt tgtgtttatg
     2941 ctggcaaaac agcaaaaggg gaagcgtggg tttcctggga aatctcagct gtgtgaggac
     3001 gcaaacggtg atggaagagc tccgaggcct ttctaaaagc agtgctccct aactcgaggt
     3061 tctgggggac actagcaaga attcttaata gttagaacct gagaagtgaa taaaagaact
     3121 tatcaccagc actcggattt cagccactac acacaattct tggaatacag aaaagtttaa
     3181 tttgaactcc ttctggatct tttaattaag ttacacactg ttttctgtga agtgtttgaa
     3241 agcaataaaa actataattt gggtaggggt tcttttttat gtatttcccc tttcaggaaa
     3301 gggtgagtca tttttgcaac ttctctcaga ctcttcagat gctgacatgt aaaacagcaa
     3361 agtaaagcta caaactcagc cacccaccca tccatccatc catccatcca gccgaccggc
     3421 agttgcaaag gtagaagcga gagtgtgcga ggggacacag caaccgtgca aacgtcagga
     3481 tcctgcattc tttagattgt ttccttttaa attaaggttt atttgattat gtgtttgtat
     3541 gcaagtgtgt tatgtgctta tgagtatagg cgcctgtgga gagcagagac gtcagggtgt
     3601 cccagagctg ggcgtacagt cagatgtgca tgtgggaact gaacctgggc attcattctc
     3661 taagagtaat attatggact ttgaactgat gagccatctc tccagatcct ttttaaggat
     3721 aaatagttct taagaccagc tgaaaggctg gatttttcca tagcaaagag acatctgacc
     3781 agagattagt ccttgttttc tactttggat tgatgataga aagcacacat aatataaaac
     3841 agggccactt ttaagtaacg cagatttttt ttaattggtt attttattta catttcaaat
     3901 gcccccttcc tagtttcccc tctgcacccc accccatcca gtccccccaa agcagcagat
     3961 cttaattctg cagtttccat attctggtgt agggcatgaa tttaaggccc gtgtgccctc
     4021 agcatgtacc agggcttcac actccagtgg actggtgact cagctcctac caactccttt
     4081 gtgtaattgt gatgttgctg agtttggttg gtagtgtgat gattttaagt tgtttttttc
     4141 ctaccacaca gcaatagcca aacaattttc ttgtttacat atgaccttta agagtctcag
     4201 cgtcaggact gggcagatga ttcagtggta aagtatttgc catgcaagca ggaagacctg
     4261 gatcctcata gaaagaaggc aggcaacatc agatggcctc catgtgtgct gacgcacacc
     4321 ctcacacaca tgaacatgcc ttcacatact ttatttttcc tttatttcta ggattttttt
     4381 cttcaatatg actagttttt agtattatcc caactcccaa aatgctctcc tcagccatct
     4441 ctgtgacctc taaaatggtc ctttttctga ggctaagatg aatgtcttta gtgtgacact
     4501 atatctcacc tatgtctcag gacctttctt ccagtctttc ctgtgcagtt aagaaccata
     4561 gctttctagt ggtggtggga gtagaaccca gacttatttg agccacatcc cagcctgagg
     4621 cataaatttc taaccacctc taagtcacct caaccaaacc actaagacct ttctatggag
     4681 gttttaggaa gcacccttta gcacactggt gttcttgggg gtgggctggg gtgtggtgcg
     4741 tgtagtgctg ttgatgccac aacttggtag atgaggccag gtcgattgat gccatcaggg
     4801 ctttgaagta tattttattc gttttcttgc taactgctat tacaatgggt attaataact
     4861 tggaagtatt ttaatagagc tagtgggaag atgcatggag cagcagtatt gccaatagag
     4921 cccatgccca ttggtgcctg tgtaggcaag agtcctgcag actcatccct cttgttgact
     4981 cacttggttt tatttcattc atccatttat ccatttgttc attcattcat ttatttattt
     5041 ctgaggcagt ctcacacagt tcaagctgtc catcttgcta tgtagcaaag ggtgaccttg
     5101 aagccctgac catcctacct ccatctgcca gagacaggga tcacatgcat gccccaccac
     5161 acactgtttt gagacaggat ctcattactt agtgcaggtt gactcccagc tcaaaattcc
     5221 catctcctcg ttacttcagt ttgaaaagta agtatctttg aggattgcat atgttttaat
     5281 catatgcact aactttcccc cttaactact tccctgatct gcttctacct ccctaccccc
     5341 agcaataaac tttaataatc c
//
