LOCUS       NM_001418256            4690 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus two pore channel 1 (Tpcn1), transcript variant 2,
            mRNA.
ACCESSION   NM_001418256 NM_001418257 XM_011248201
VERSION     NM_001418256.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4690)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4690)
  AUTHORS   de Zelicourt,A., Fayssoil,A., Mansart,A., Zarrouki,F., Karoui,A.,
            Piquereau,J., Lefebvre,F., Gerbaud,P., Mika,D.,
            Dakouane-Giudicelli,M., Lanchec,E., Feng,M., Leblais,V., Bobe,R.,
            Launay,J.M., Galione,A., Gomez,A.M., de la Porte,S. and
            Cancela,J.M.
  TITLE     Two-pore channels (TPCs) acts as a hub for excitation-contraction
            coupling, metabolism and cardiac hypertrophy signalling
  JOURNAL   Cell Calcium 117, 102839 (2024)
   PUBMED   38134531
REFERENCE   3  (bases 1 to 4690)
  AUTHORS   Just,A., Mallmann,R.T., Grossmann,S., Sleman,F. and Klugbauer,N.
  TITLE     Two-pore channel protein TPC1 is a determining factor for the
            adaptation of proximal tubular phosphate handling
  JOURNAL   Acta Physiol (Oxf) 237 (3), e13914 (2023)
   PUBMED   36599408
  REMARK    GeneRIF: Two-pore channel protein TPC1 is a determining factor for
            the adaptation of proximal tubular phosphate handling.
REFERENCE   4  (bases 1 to 4690)
  AUTHORS   Royer,J., Cancela,J.M. and Edeline,J.M.
  TITLE     Unexpected Motherhood-Triggered Hearing Loss in the Two-Pore
            Channel (TPC) Mutant Mouse
  JOURNAL   Biomedicines 10 (7), 1708 (2022)
   PUBMED   35885013
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4690)
  AUTHORS   Mallmann,R.T. and Klugbauer,N.
  TITLE     Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial Learning
            and Memory
  JOURNAL   Behav Genet 50 (6), 401-410 (2020)
   PUBMED   32889694
  REMARK    GeneRIF: Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial
            Learning and Memory.
REFERENCE   6  (bases 1 to 4690)
  AUTHORS   Zong,X., Schieder,M., Cuny,H., Fenske,S., Gruner,C., Rotzer,K.,
            Griesbeck,O., Harz,H., Biel,M. and Wahl-Schott,C.
  TITLE     The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release
            from lysosomal stores
  JOURNAL   Pflugers Arch 458 (5), 891-899 (2009)
   PUBMED   19557428
REFERENCE   7  (bases 1 to 4690)
  AUTHORS   Yu,X., Bauer,K., Wernhoff,P., Koczan,D., Moller,S., Thiesen,H.J.
            and Ibrahim,S.M.
  TITLE     Fine mapping of collagen-induced arthritis quantitative trait loci
            in an advanced intercross line
  JOURNAL   J Immunol 177 (10), 7042-7049 (2006)
   PUBMED   17082620
REFERENCE   8  (bases 1 to 4690)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   9  (bases 1 to 4690)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 4690)
  AUTHORS   Perelygin,A.A., Scherbik,S.V., Zhulin,I.B., Stockman,B.M., Li,Y.
            and Brinton,M.A.
  TITLE     Positional cloning of the murine flavivirus resistance gene
  JOURNAL   Proc Natl Acad Sci U S A 99 (14), 9322-9327 (2002)
   PUBMED   12080145
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125183.4.
            
            On or before Mar 23, 2023 this sequence version replaced
            NM_001418257.1, XM_011248201.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1262437.1,
                                           SRR13948564.2249045.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               AC125183.4         122626-122778
            154-397             AC125183.4         125838-126081
            398-525             AC125183.4         150923-151050
            526-702             AC125183.4         153320-153496
            703-816             AC125183.4         154681-154794
            817-947             AC125183.4         155268-155398
            948-1036            AC125183.4         156045-156133
            1037-1071           AC125183.4         156956-156990
            1072-1130           AC125183.4         157455-157513
            1131-1230           AC125183.4         157724-157823
            1231-1347           AC125183.4         161224-161340
            1348-1472           AC125183.4         161651-161775
            1473-1521           AC125183.4         162947-162995
            1522-1585           AC125183.4         163268-163331
            1586-1630           AC125183.4         163773-163817
            1631-1687           AC125183.4         165952-166008
            1688-1741           AC125183.4         166138-166191
            1742-1814           AC125183.4         166781-166853
            1815-1922           AC125183.4         167814-167921
            1923-1994           AC125183.4         168740-168811
            1995-2084           AC125183.4         169299-169388
            2085-2200           AC125183.4         170577-170692
            2201-2247           AC125183.4         171431-171477
            2248-2316           AC125183.4         171988-172056
            2317-2401           AC125183.4         172179-172263
            2402-2541           AC125183.4         173315-173454
            2542-2622           AC125183.4         173625-173705
            2623-4690           AC125183.4         175042-177109
FEATURES             Location/Qualifiers
     source          1..4690
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 60.63 cM"
     gene            1..4690
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /note="two pore channel 1"
                     /db_xref="GeneID:252972"
                     /db_xref="MGI:MGI:2182472"
     exon            1..153
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            154..397
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..2739
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /note="isoform a is encoded by transcript variant 2; two
                     pore calcium channel protein 1; voltage-dependent calcium
                     channel protein TPC1"
                     /codon_start=1
                     /product="two pore calcium channel protein 1 isoform a"
                     /protein_id="NP_001405185.1"
                     /db_xref="GeneID:252972"
                     /db_xref="MGI:MGI:2182472"
                     /translation="MAVSLDDDVPLILTLDEAESAPLPPSNSLGQEQLPSKNGGSHSI
                     HNSQVPSLVSGADSPPSSPTGHNWEMNYQEAAIYLQEGQNNDKFFTHPKDARALAAYL
                     FVHNHFFYMMELLTALLLLLLSLCESPAVPVLKLHTYVHATLELFALMVVVFELCMKL
                     RWLGFHTFVRHKRTMVKTSVLVVQFIEAIVVLVRQTSHVRVTRALRCIFLVDCRYCGG
                     VRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSTNPSDPYFSTLENSIVNLFV
                     LLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEKHKFKS
                     LLLHKRTAIQHAYGLLASQRRPAGISYRQFEGLMRFYKPRMSARERFLTFKALNQSNT
                     PLLSLKDFYDIYEVAALQWKAKRNRQHWFDELPRTAFLIFKGINILVNSKAFQYFMYL
                     VVAVNGVWILVETFMLKGGNFTSKHVPWSYLVFLTIYGVELFMKVAGLGPVEYLSSGW
                     NLFDFSVTAFAFLGLLALTLNMEPFYFIVVLRPLQLLRLFKLKKRYRNVLDTMFELLP
                     RMASLGLTLLTFYYSFAIVGMEFFNGRLTPNCCNTSTVADAYRFINHTVGNKTKVEEG
                     YYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTI
                     IVAFILEAFVFRMNYSRKSQDSEVDSGIVIEKEMSKEELMAVLELYREERGTSSDVTR
                     LLDTLSQMEKYQQNSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQKLRGSV
                     PGPAAQQPPGSRQRSQTVT"
     exon            398..525
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            526..702
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            703..816
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            817..947
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1036
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1071
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1130
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1230
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1347
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1472
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1521
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1585
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1630
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1687
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1741
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1814
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1922
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..1994
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2084
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2200
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2201..2247
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2316
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2317..2401
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2402..2541
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2622
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2623..4690
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4668..4673
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /note="hexamer: AATAAA"
     polyA_site      4690
                     /gene="Tpcn1"
                     /gene_synonym="5730403B01Rik; mKIAA1169; Tpc1"
                     /note="major polyA site"
ORIGIN      
        1 gcagctgccg ctgtggcagc ggtgaggcgg cggtggcggc tgctgaggct ccgcgctggg
       61 gatattggcg gcggcaactg cgggctgagc tacgctgtgc agacccagtg cacagtgcgg
      121 gatcccggga cggcgcgtgt aaggatccga gggaccttag aagatgcctc tgatggaaca
      181 ggctctggga agcttccccg gccccgtggc tttgaacagg agctcaagcc ggaggcagtt
      241 taaagccctg gccgttgtat cctgaggacc gcaggtcagg agaagatggc tgtaagttta
      301 gatgacgatg tgccgctcat cctgaccttg gacgaggctg agagtgctcc gctgcctcct
      361 tcgaacagcc tgggccaaga gcagctgccc agcaaaaatg ggggcagcca cagcatccac
      421 aactcccagg tccccagtct ggtctccgga gcggacagcc ccccctccag tcccaccgga
      481 cacaactggg agatgaatta tcaagaggcg gcaatctacc tccaggaagg tcagaacaac
      541 gacaagttct tcacccaccc caaggatgcc agagcgctgg cggcctacct cttcgtccac
      601 aaccacttct tctacatgat ggagctgctc acggccctgc tcctgctgct gctgtcgctg
      661 tgcgagtccc ccgctgtccc cgtgctcaag ctgcacactt acgtccacgc cacgctggaa
      721 ctctttgccc tcatggtggt ggtatttgaa ctctgcatga aattgcggtg gctgggcttc
      781 cacacgttcg tccggcacaa acgtaccatg gtcaagacgt ccgtcctcgt ggtgcagttc
      841 atcgaggcca ttgtggtgct ggttcggcag acgtcccacg tgcgggtgac ccgggcacta
      901 cgctgcattt tcctggtgga ctgtcgctac tgtggcggtg tacggcgcaa cctgcggcag
      961 atcttccagt ctctcccacc cttcatggac atcctcctgt tgctgctctt ctttatgatc
     1021 atctttgcca tcctcggttt ctacttattc tccacaaatc cttccgaccc ctacttcagc
     1081 accctggaga acagcatcgt caacctgttc gttctcctga ccacagccaa ctttccagat
     1141 gtcatgatgc cctcctactc ccggaacccc tggtcctgcg tcttcttcat tgtatacctc
     1201 tccattgagc tgtacttcat catgaacctg ctcctggccg tggtgttcga caccttcaac
     1261 gacattgaaa agcacaagtt caagtctttg ctgctgcaca aacggaccgc catccagcat
     1321 gcctacggcc tgcttgccag ccaacggagg ccggctggca tctcctacag gcagttcgaa
     1381 ggcttaatgc gcttctacaa gccccggatg agtgcaaggg aacgcttcct gactttcaag
     1441 gccttgaacc agagcaacac gcctctgctc agcctgaagg acttctatga tatttacgaa
     1501 gtcgctgctc tgcagtggaa ggcaaagaga aacagacagc attggtttga tgagctcccc
     1561 cggacagcct tcctcatctt caaagggatt aacatccttg tgaattccaa ggccttccag
     1621 tatttcatgt acttggtggt ggctgtcaac ggtgtctgga tcctggtgga gacattcatg
     1681 ttgaaaggtg ggaatttcac ctcaaagcat gtgccctgga gttacctcgt gtttcttacc
     1741 atctatggag ttgaactgtt catgaaggtg gctggcctgg gccctgtgga gtacctgtcc
     1801 tctggatgga acctgttcga tttctcggtc acggcattcg ccttcctggg actgctcgca
     1861 ctgacgctca acatggaacc cttctatttc attgtggtcc tgcgtcccct tcagctgctg
     1921 aggttattta aactgaagaa acgctaccgc aacgtgttgg acaccatgtt tgagctgctg
     1981 ccgcggatgg ccagccttgg cctcacgctg ctcaccttct actattcctt cgccatcgtg
     2041 ggcatggagt tcttcaacgg gcggctgacc cccaactgct gcaacaccag cacagtggcc
     2101 gacgcctacc ggttcatcaa ccacactgtg ggcaataaga ccaaggtaga ggaaggctac
     2161 tactatctca acaactttga caacatcctc aacagcttcg tgaccttgtt tgagctcacc
     2221 gttgtcaaca attggtacat catcatggaa ggcgtcacct cgcagacgtc ccactggagc
     2281 cgcctgtact tcatgacctt ttacatagtg accatggtgg tgatgaccat tatcgtggcc
     2341 ttcatcctgg aggccttcgt cttccgcatg aactacagcc gcaagagcca ggactcggaa
     2401 gtggacagtg gcatcgtcat cgagaaggaa atgtccaagg aggagcttat ggccgtcctg
     2461 gagctttatc gtgaggagcg aggcacctcc tctgacgtga cccggctgct ggacaccctc
     2521 tctcagatgg agaaatacca gcaaaattcc atggtgtttc tgggacggcg atcgagaacc
     2581 aaaagtgacc tgagtctgaa gatgtaccag gaggagatcc aggagtggta cgaggagcat
     2641 gcccgggaac aggagcagca gaagctcagg ggcagcgtgc ccggccctgc agcccagcag
     2701 ccccctggca gtcgccagcg ctcccagact gtcacctagc tgggtttcgt caagccagcc
     2761 tcttctatgc aataacacca tagtattatg tactaggacg tatgggaacc atgtgtgtat
     2821 gtagacacac tcatatatat gcacatattt acacagagac agaaaagaga ctatagccag
     2881 ggtccgttcc agccacctcg ctctgtcttc ctgagctcca gaaataacca gcttaggctg
     2941 gaggcccagg cctggcggag ctctcgtcct accatggaaa actctggaag ccctctgctc
     3001 aagaagcccc ttaaataggc tatctcgtct cagcaatgcc ggctttcccc ggggagggat
     3061 ggggggagct tgaccgcctc cctactgcgg cctccagctt cgtccctacc tgaaccccag
     3121 ccaacacagg tgtctgtgtc tggtatgagg atcaaaacca ctaggaagaa accccacacc
     3181 ctgcaggatg acatctatca atgacaaaag tgttagaagg ttcccttgag ggagacagaa
     3241 gagcttactc tctcaggctc ccagtccttt cttgttgctg gaaccctacc acaactcccc
     3301 cacccccacc cccgggaacc cccaccccca cccccggcag gatccctcca tgcaggagaa
     3361 agccaaccag aggccctggg aatttgactt gctcagggga gttcatttga actggtgctg
     3421 aaggcagccc ccctcaccaa ccacactttc acactgcctc ctccaagatt ctcataagct
     3481 aggtgggtag gggtggcgag tcaggtcagg tgacttgtgg gagttctttt gaggccacca
     3541 tagtatatgg tggcagagcg atggagccct gctgtgttgt ccacaagggg ctgaaggtgg
     3601 gcagggcccg aagttgccta gcacccccac ccccccaccc ctgcgcactc cctccaggct
     3661 aacctggcct tccaaacctg ctgttgcttg ggagttggag tgggcaggca cagccccccc
     3721 ctcctgttct cccagccgca gaaccagggg tcaagctgga aagcggatgt ttttacttta
     3781 aataaagcac agttgccccc ccccccccaa tacatacact atcccccagg aaaaacctct
     3841 ggtttccaca gagagtcagg agactggcca agtcccttcc acttcaaaga gctcttggcc
     3901 tccacttgga ctccagttcc caaccctgag aagcagtttc atttccatag ccggttgcct
     3961 tagcttcttt gtgtgtgagg ggcattttgg aagcagaaag aggggaggcc tataaagagg
     4021 gcggtggggg gggggaggct ctgagcaact gcctggttct aggccccttc ctctacccca
     4081 ggtaccctca gcctagggga gcaggctcag gtggaaggga ctggtcttgg gccccatgta
     4141 gaggtactaa aacccctggg tctagcacat accagccagg tgcctgagca agacagggcc
     4201 ctcaggccaa actgtagccc cacagagtca cctttgagca cacaccaagc tgaccctcaa
     4261 acttgctagc caggcaggga acagactgtg tcgcccaggg ctgtaagctg agacccctgg
     4321 gatccctgtc taagctagat gccccttccc tccattcagc agagtgagaa ctagtggctc
     4381 cgtgtcacag cctagcaggg gcagctacgg aaccaccacg ctgcttctcc cgagtgggga
     4441 tagggcactc tgtgggaacc accacgctgc ttctcccgag tggggatagg gcactctgtg
     4501 ggaacagtgt ccggcccctc cctctcgctt ctccaccccc tccaccccag ccttactcca
     4561 caccgtgcag acaatcattt tgtatgggtt aagagccacg tcgtcggaag gttttataca
     4621 gtgatttgtt acctaggaac gcactgtgcc cagatttctg gtgtgccaat aaaagagcct
     4681 ctgctttata
//
