LOCUS       NM_172913               3212 bp    mRNA    linear   ROD 11-OCT-2023
DEFINITION  Mus musculus TOX high mobility group box family member 3 (Tox3),
            mRNA.
ACCESSION   NM_172913 XM_909706
VERSION     NM_172913.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3212)
  AUTHORS   Bohuslavova R, Fabriciova V, Smolik O, Lebron-Mora L, Abaffy P,
            Benesova S, Zucha D, Valihrach L, Berkova Z, Saudek F and
            Pavlinkova G.
  TITLE     NEUROD1 reinforces endocrine cell fate acquisition in pancreatic
            development
  JOURNAL   Nat Commun 14 (1), 5554 (2023)
   PUBMED   37689751
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3212)
  AUTHORS   Zhu Q, Ge J, Liu Y, Xu JW, Yan S and Zhou F.
  TITLE     Decoding anterior-posterior axis emergence among mouse, monkey, and
            human embryos
  JOURNAL   Dev Cell 58 (1), 63-79 (2023)
   PUBMED   36626872
REFERENCE   3  (bases 1 to 3212)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3212)
  AUTHORS   Li H, Zhu Y, Morozov YM, Chen X, Page SC, Rannals MD, Maher BJ and
            Rakic P.
  TITLE     Disruption of TCF4 regulatory networks leads to abnormal cortical
            development and mental disabilities
  JOURNAL   Mol Psychiatry 24 (8), 1235-1246 (2019)
   PUBMED   30705426
REFERENCE   5  (bases 1 to 3212)
  AUTHORS   Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong
            Y, Bettini M, Zong C, Martin JF and Borowiak M.
  TITLE     Endocrine lineage biases arise in temporally distinct endocrine
            progenitors during pancreatic morphogenesis
  JOURNAL   Nat Commun 9 (1), 3356 (2018)
   PUBMED   30135482
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3212)
  AUTHORS   Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND and Robson P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   7  (bases 1 to 3212)
  AUTHORS   Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K,
            Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P,
            Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide
            W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T,
            van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A,
            Teasdale RD, Tegner J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya
            N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R,
            Kitazume Y, Kawai J, Hume DA, Ideker T and Hayashizaki Y.
  TITLE     An atlas of combinatorial transcriptional regulation in mouse and
            man
  JOURNAL   Cell 140 (5), 744-752 (2010)
   PUBMED   20211142
  REMARK    Erratum:[Cell. 2010 Apr 16;141(2):369. Kamburov, Atanas [added];
            Kaur, Mandeep [added]; MacPherson, Cameron Ross [added];
            Radovanovic, Aleksandar [added]; Schwartz, Ariel [added]]
REFERENCE   8  (bases 1 to 3212)
  AUTHORS   Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S,
            Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N,
            Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y,
            Okado H, Hashimoto M and Asahara H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   9  (bases 1 to 3212)
  AUTHORS   Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM,
            Basile A, Andre A, Cocchia M, Guardiola O, Ballabio A, Rubenstein
            JL and Zollo M.
  TITLE     Telencephalic embryonic subtractive sequences: a unique collection
            of neurodevelopmental genes
  JOURNAL   J Neurosci 25 (33), 7586-7600 (2005)
   PUBMED   16107646
REFERENCE   10 (bases 1 to 3212)
  AUTHORS   Wise TL and Pravtcheva DD.
  TITLE     Oligosyndactylism mice have an inversion of chromosome 8
  JOURNAL   Genetics 168 (4), 2099-2112 (2004)
   PUBMED   15611179
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK619337.1 and BC052044.1.
            
            [WARNING] On Dec 12, 2023 this sequence was replaced by
            NM_172913.4.
            
            On Mar 27, 2008 this sequence version replaced NM_172913.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052044.1, AK082602.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               CK619337.1         92-365
            275-3212            BC052044.1         1-2938
FEATURES             Location/Qualifiers
     source          1..3212
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 43.96 cM"
     gene            1..3212
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /note="TOX high mobility group box family member 3"
                     /db_xref="GeneID:244579"
                     /db_xref="MGI:MGI:3039593"
     exon            1..390
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     CDS             304..2031
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /note="trinucleotide repeat containing 9; trinucleotide
                     repeat-containing gene 9 protein"
                     /codon_start=1
                     /product="TOX high mobility group box family member 3"
                     /protein_id="NP_766501.2"
                     /db_xref="CCDS:CCDS22516.1"
                     /db_xref="GeneID:244579"
                     /db_xref="MGI:MGI:3039593"
                     /translation="MDVRFYPAAAGDPAGLDFAQCLGYYGYSKLGNNNYMNMAEANNA
                     FFAASEQTFHTPSLGDEEFEIPPITPPPESDPTLGMPDALLPFQTLSDPLPSQGTEFT
                     PQFPPQSLDLPSITISRNLVEQDGVLHSNGLHMDQSHTQVSQYRQDPSLVMRSIVHMT
                     DGARSGIMPPAQLTTINQSQLSAQLGLNLGGANVSHTSPSPPASKSATPSPSSSINEE
                     DADDANRAIGEKRTAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQN
                     PNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESA
                     EAQTIRSVQQTLASTNLTSSLLLNTSLSQHGTVPASPQTLPQSLPRSIAPKPLTMRLP
                     MSQIVTSVTIAANMPSNIGAPLISSMGTTMVGSATSTQVSPSVQTQQHQMQLQQQQQQ
                     QQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQQHLQQQLSQQQLQQQ
                     LQQHLQLQQLQHMQHQSQPSPRQHSPVTSQITSPIPAIGSPQPASQQHQPQIQSQTQT
                     QVLPQVSIF"
     exon            391..453
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     exon            454..708
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     exon            709..978
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1206
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1287
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..3195
                     /gene="Tox3"
                     /gene_synonym="500-9; C230068E13; CAGF9; Tnrc9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctgcgcc ccgcgccccg ggcgcccggc ccgcgcgcag ccagcttcgg tgtcccggtg
       61 gggcgcgtcc ctcgggccgc ctcccgctct cccgcggctc gcgtggccgc gcctttgtgt
      121 gctgcagccg cagctcccgg gctcgtcggc ggcccccgcg cgacgcccct acagtcccac
      181 ggcccgtgcg ctgtccccgg gcgcccccgg ccgggcgtcc tcgacggtgg atcgtacggc
      241 cgcgaggagg cgggtagcgg ccccggcgag ttccagcccc ggcccccagc ccccggcccc
      301 ggcatggatg tgaggttcta ccccgcggcg gccggggacc cagccggcct ggacttcgcg
      361 cagtgcctgg ggtactacgg ctacagcaag ttgggaaata ataactacat gaacatggcc
      421 gaggcaaaca acgccttctt tgctgccagt gagcagacat tccacacgcc aagccttggg
      481 gacgaagagt ttgaaattcc accgatcacg cctcctccag agtcagaccc caccctgggt
      541 atgcctgatg cactgctacc ctttcagact ctcagcgatc cgttgccttc ccagggaact
      601 gagttcacac cccagtttcc ccctcaaagc ctggatctcc cttccatcac aatctcaagg
      661 aatctggtgg agcaagatgg cgtgcttcat agcaatgggc tgcacatgga tcagagccac
      721 acacaagtgt cacagtaccg ccaggatccc tctttggtca tgaggtcaat tgtccatatg
      781 acggatggtg ctcgatctgg gatcatgcct cctgcccagc tgaccaccat caaccagtct
      841 cagctcagcg cacagctggg cttgaatttg ggaggagcca atgtgtccca cacatctcct
      901 tcacctccag caagcaaatc agccactccc tctccttcca gctctatcaa cgaagaggat
      961 gctgatgatg caaacagagc cattggagag aaaagaacag ccccagattc tggcaagaag
     1021 cccaagactc caaagaaaaa gaaaaagaaa gatcccaacg agcctcagaa gccagtgtca
     1081 gcatatgccc tgtttttcag agatacacag gctgcaatta agggtcaaaa ccccaacgca
     1141 accttcggag aagtctcgaa aatcgtagca tctatgtggg acagccttgg ggaggagcaa
     1201 aagcaggtat ataaaaggaa aacagaagct gccaagaaag aatacttgaa ggccctggct
     1261 gcctaccggg ctagcctcgt ttccaaggct gctgctgaat ctgcagaagc ccagaccatc
     1321 cgttctgtcc agcagactct ggcatcaacc aacctgacat cctccctcct cctgaacaca
     1381 tcactgtctc aacatgggac agtcccagcc tcacctcaga ctcttccaca gtcactccct
     1441 aggtcaattg cccccaaacc cttaaccatg agactaccca tgagccagat cgtcacatca
     1501 gtcaccattg cagccaacat gccctcgaac attggggctc cactgataag ttccatgggg
     1561 acgaccatgg ttggttcagc aacctccacc caggtgagcc cttcggtgca aacccagcag
     1621 catcagatgc agttgcagca gcaacagcag cagcagcagc agatgcagca gatgcagcag
     1681 cagcagttac agcagcacca aatgcatcag cagatccagc agcagatgca gcagcagcat
     1741 tttcagcatc acatgcagca gcacctgcag cagcagcaac agcagcatct ccagcagcag
     1801 ctcagccaac agcagctgca gcagcagttg cagcagcatc tccagctgca gcaactgcag
     1861 cacatgcagc accagtctca gccttctccc cggcagcact cgcccgtcac ctcacagatc
     1921 acgtccccca tccccgccat tggcagcccc cagccagcct ctcagcagca ccagcctcaa
     1981 atccagtcgc agactcagac tcaagtgtta ccgcaggtca gtattttcta aggtgcgcga
     2041 ggcacacgga tctgagtgag gcgtaggagg gaaggcgcat ggactggaac ttgcaagttg
     2101 actctggtta tgcaagaatg tgtaacagat caagagatcc tctcaagtgt ctattagata
     2161 ggcaataaga actgcagtgt agctgggaag catcttttag ccgactatac atcactttgt
     2221 tttgaaacaa ggaagctgcg ctctgtcatg tgctgccttt tttatttatt caggctaaac
     2281 ctacaatatg tgaatcaacc cgtttaatga atcctgggac atgctgatga ctgtaaactg
     2341 gcctttccga gtcatagaaa aaaaaaagat ggccttattt ctccagaagt gagtgaacca
     2401 cacttccagg ctatttgaac ttctgaagcc ctaaaataaa taactaagta caaagcacag
     2461 ttgtaactac ctgaaatatg aagatccagt ttcatacaaa catttgtatg atgtgaatag
     2521 ttgatggcat ttttttgtca tgaaaaaaaa ataatgtaaa tcacagactt ttgccaaagc
     2581 tcttattttt tttctaaatc tctccagaaa aaaattgcaa gtgattagat tcaattattg
     2641 atttatttac ttctactttg tatccatgac ttctccgaat caaaccacgg tatatgttgt
     2701 gacaatatct atggccactg ttagcccatt atgttcattc caattagaag aaatgtgaat
     2761 actatattac gtgttttgag tgacgagttt gggaaaataa aaacactgta tttttaaaag
     2821 ggaaatgcac ttaaatgaaa acagttatta caaaagttaa gatttaaaaa aaagaaaaag
     2881 caagagtttt tattatgatg taataccggt agaatattga atatttaaaa ggcacactac
     2941 atctgatagt caatgtaaat attttctttc caagttgtaa gttttcatat catgtgttgt
     3001 aaagttttcc taaacgaggc tttaacgtaa acactggtga cataaaccat tcattgctac
     3061 cttgcttatt gtgtttttac gcggttttat acttttttta tgagttatga tagcagcaat
     3121 tacgttgttt gtattttgct taactaaaac aaaaatgctt ttatcttgct atagaataaa
     3181 cacatttcag taaaaaaaaa aaaaaaaaaa aa
//
