LOCUS       NM_001199736            5177 bp    mRNA    linear   ROD 03-AUG-2024
DEFINITION  Mus musculus testis and ovary specific PAZ domain containing 1
            (Topaz1), mRNA.
ACCESSION   NM_001199736 XM_001474362 XM_001477413
VERSION     NM_001199736.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5177)
  AUTHORS   Chadourne,M., Poumerol,E., Jouneau,L., Passet,B., Castille,J.,
            Sellem,E., Pailhoux,E. and Mandon-Pepin,B.
  TITLE     Structural and Functional Characterization of a Testicular Long
            Non-coding RNA (4930463O16Rik) Identified in the Meiotic Arrest of
            the Mouse Topaz1-/- Testes
  JOURNAL   Front Cell Dev Biol 9, 700290 (2021)
   PUBMED   34277642
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5177)
  AUTHORS   Luangpraseuth-Prosper,A., Lesueur,E., Jouneau,L., Pailhoux,E.,
            Cotinot,C. and Mandon-Pepin,B.
  TITLE     TOPAZ1, a germ cell specific factor, is essential for male meiotic
            progression
  JOURNAL   Dev Biol 406 (2), 158-171 (2015)
   PUBMED   26358182
  REMARK    GeneRIF: TOPAZ1, a germ cell specific factor, is essential for male
            meiotic progression.
REFERENCE   3  (bases 1 to 5177)
  AUTHORS   Baillet,A., Le Bouffant,R., Volff,J.N., Luangpraseuth,A.,
            Poumerol,E., Thepot,D., Pailhoux,E., Livera,G., Cotinot,C. and
            Mandon-Pepin,B.
  TITLE     TOPAZ1, a novel germ cell-specific expressed gene conserved during
            evolution across vertebrates
  JOURNAL   PLoS One 6 (11), e26950 (2011)
   PUBMED   22069478
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124778.4, HM631980.1 and BG075226.2.
            
            On Feb 12, 2019 this sequence version replaced NM_001199736.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HM631980.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AC124778.4         44035-44181         c
            148-5116            HM631980.1         1-4969
            5117-5177           BG075226.2         1-61                c
FEATURES             Location/Qualifiers
     source          1..5177
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 73.1 cM"
     gene            1..5177
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /note="testis and ovary specific PAZ domain containing 1"
                     /db_xref="GeneID:671232"
                     /db_xref="MGI:MGI:3779933"
     exon            1..364
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..5109
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /note="topaz 1; testis and ovary-specific PAZ domain gene
                     1; testis- and ovary-specific PAZ domain-containing
                     protein 1"
                     /codon_start=1
                     /product="protein TOPAZ1"
                     /protein_id="NP_001186665.1"
                     /db_xref="CCDS:CCDS57718.1"
                     /db_xref="GeneID:671232"
                     /db_xref="MGI:MGI:3779933"
                     /translation="MRPPATPPDPTKEPGCKGTTRGLRKRGLPLTPEPGEGGGCSLEA
                     RGCEEESRQKQRMVTQASGREETEGDKLAKENGKITEAPSDDPQPGTDLVRKTSITSS
                     ESLQTVECSEFQNMAFLQSLDKEELGEGIKRRMRIKKCKSLENPPLEITKNEATQNIK
                     VEFQDELFKNTPKHSCNSLSPGVEKNCSFELHDYSFLHSEGCNNENNFEDKPHDVCLH
                     TEENSLKLKKENLRNLAEKDDTRTTTKLLKTEKSVIASKLLLEESHLYQNKNNGLTSC
                     LQSEKNKYSVEENNTGRKHRKKMKSGKEEKNINLTLSNVCNNSVLVLQENQMGMEGKE
                     AETLEPKKSFLKALRKINHNTLPPVDHLCLPKTVGKTSSRHHINAMLQKTLESSLKED
                     IKNTSESLGCKRIEPEKYNKSMISSTVKSPSDGHHMEKRSPRGDLRSETEESKVSCCR
                     TIPMTGKRVWPFYSCARISAQCWKKTSLSDLNYSLLGPLENVRQHDSIIHQMNQTHLP
                     DSKLLQPSLTERTTESSRKEMYDSDLSCLSSVSSVESTVMDIKEAMSHDKKTKLEEPS
                     RNGAEVVSNATEDTQLSNITQSLTGNKKRKGNLSKLNLTVASQESQETNNCANKTVHR
                     KVCITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGAVSARSSEREAYSPLELLD
                     SLSGVEAKQNRNKENICTTSGPQSLNLHSCIAPGQASSHSFYNKNSCTSSSFTKKGYD
                     NKACNHISEPGNIISNKESISMKIENNTFSCDLGYIDQSSFCSKKQEAFVPISSEISG
                     RKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQE
                     PRVSEDQPTADFKHMHLPGKKEPGDLSKEVALLDPGLLKLESCPSLSAAKEPQHDPEG
                     AAISLEATEETVVSGSLEGLSEQARASDSDAKCISSDKATVMEEQESTHEIFKSKDSR
                     NVESATECQLATLGPNPLCSSALPVNLSSHQDVVSTPWINDVRFPGRHSVLQLQNPET
                     CEIFKREKNMGVFQKPLGLLIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDV
                     FRKYISVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVV
                     QLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDPEHLNYIVK
                     LLHQAQASQQEISAVLQAKSRLRVRQLKKNWKCDLDSALSEVETCKEKSDWTKLGNLY
                     ISIKMSCEEFADLQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLL
                     GRIGISAVYFYHRLLLWAKGRKVLDILYELKIHFTSLKGLTGPEKEAPRCQIVNVAAE
                     IFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHEILGKNLYKQTF
                     EVLRNLPSFQNSQEMMGVSQSSLLFNELLDACIESNSLGISSSVAEFMVAKSIPIDFS
                     FLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLHRKLLLVPSYLSEIEMLLAM
                     EIFLVSNASGIQSAGMGAPTQVLQIVLKRCEESKSRSKDEYQAAVERLVMAARISDPK
                     LFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH"
     exon            365..2795
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            2796..2860
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            2861..2985
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            2986..3050
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3051..3184
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3185..3270
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3271..3396
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3397..3460
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3461..3612
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3613..3705
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3706..3821
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3822..3888
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            3889..4063
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4064..4164
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4165..4330
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4331..4495
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4496..4699
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4700..4889
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
     exon            4890..5177
                     /gene="Topaz1"
                     /gene_synonym="671232; Gm9524"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacttccgct tcctgtagtg tcgggtacag ggtcggaagc gaggccaggc cgggccaggg
       61 tgggcagtag cctgtgtcct gcagggggag cagcggctct aggccgtcta ggcttcccag
      121 agaggctgag tgggcggctg tgggcggatg cggccgccag cgacgccccc agacccgacc
      181 aaggagccag ggtgcaaagg caccacccga ggcctgagga agcgaggcct tccgctgacg
      241 ccagagccag gcgagggggg aggctgcagc ctggaggcca gggggtgcga ggaggagagc
      301 aggcagaagc agaggatggt gacccaggct tctgggagag aagagacaga aggtgacaag
      361 ttggccaaag agaatggaaa aattactgag gccccaagtg atgatccaca gccagggact
      421 gacctggtaa gaaagacatc aataaccagt tcggagtctt tgcaaacagt ggagtgcagt
      481 gaatttcaaa atatggcttt cttacagtct ttggataagg aagaattggg agaaggtatt
      541 aaaagaagaa tgcgaattaa aaaatgtaaa agtttagaaa atccacctct tgaaataact
      601 aaaaatgagg caacacaaaa tattaaagtt gaattccaag atgaactgtt caagaatacc
      661 ccaaaacatt cttgtaacag cttatcacct ggagtagaaa aaaattgcag ctttgaattg
      721 catgattaca gttttctcca ttctgaaggt tgtaataatg aaaacaactt tgaggataaa
      781 cctcatgatg tatgtctaca cactgaagag aactctttga agttaaagaa agaaaacctt
      841 aggaatcttg cagagaaaga tgacacaaga actactacta agcttttaaa aactgaaaaa
      901 agtgtaatag ccagtaagtt actgcttgaa gaaagtcatt tataccaaaa taaaaacaat
      961 ggcttgactt cttgccttca aagtgaaaaa aacaaatatt cagtagagga gaacaacact
     1021 gggagaaaac acaggaaaaa aatgaagtct ggaaaagaag aaaaaaatat taatcttact
     1081 ttgtctaatg tatgtaacaa ttctgtgttg gtgttacaag aaaaccaaat gggtatggaa
     1141 gggaaagaag cagagacctt agaacctaaa aaaagttttc taaaagcttt aagaaaaata
     1201 aaccataata cactccctcc ggtggaccat ttgtgtctcc ccaaaacagt ggggaaaaca
     1261 agttctaggc atcacataaa tgctatgctt cagaaaaccc tcgaatcaag tttgaaagag
     1321 gatataaaaa atacttcaga gtccttagga tgcaaacgta tagagccaga aaaatataat
     1381 aaatcgatga taagctctac agtgaaatca cctagtgacg gccatcatat ggaaaagaga
     1441 tctccacggg gagatctgag aagtgaaact gaagagtcaa aggttagctg ttgcagaaca
     1501 ataccaatga ctggtaaaag agtttggcct ttttattctt gtgctagaat atctgcccag
     1561 tgttggaaaa agacttcctt gtcagattta aattactcac ttctggggcc actggaaaat
     1621 gttaggcaac atgattctat aatacaccaa atgaaccaga ctcacttacc tgactctaaa
     1681 ctgttacaac catccttaac agaaagaact actgagtcct caagaaaaga aatgtatgat
     1741 tctgatttaa gttgtttgtc ttcagtttct tcagtagaat ctactgtgat ggatataaag
     1801 gaagctatgt cccatgataa aaagacaaag ttagaggaac ccagcagaaa tggggcagag
     1861 gtagtttcta atgcaactga agacacccag ttaagtaata taactcaaag cttaacagga
     1921 aataagaaaa ggaaagggaa tttatcaaaa cttaatttaa cagttgcatc ccaagagagc
     1981 caggaaacaa ataactgtgc aaataaaact gttcatcgaa aagtttgtat tactaagcaa
     2041 acacttgtgg caccggactt ggttaaaata ttaaacacgg gacggctgac taattttaaa
     2101 atccctttac taaagaacaa gacaggaaaa agaggagcag taagtgccag gtcatctgag
     2161 agagaagctt atagccccct agagctactt gacagtttat ctggagtaga ggcaaaacaa
     2221 aataggaata aggaaaatat ctgtacaact tcaggaccac agtctttgaa tttacatagt
     2281 tgtatagctc cagggcaagc tagttctcat tcattctaca ataagaattc ctgtacttct
     2341 tcgagcttta ccaagaaagg ttacgataat aaagcatgta atcacatctc tgaaccagga
     2401 aatattattt caaataagga gtctatttct atgaaaattg aaaataatac cttttcttgt
     2461 gatcttggat atattgatca aagttccttc tgctctaaga aacaagaagc atttgtgcca
     2521 atttcctctg aaattagtgg tagaaaaatg actaaaagca tttcagaact caaattgggg
     2581 tttccagata ttcttaaagc atatgaagat gatgtcctct tgattgatgt aattcaagat
     2641 gatccagagc tctttggaat ctccagtgag ggggatcttt cctttgcttc agaagtctcc
     2701 aagataagcc aggagcccag agtatctgaa gaccaaccaa cagcagattt taagcacatg
     2761 caccttccag ggaaaaaaga accaggcgat ttgagtaaag aagttgcctt gctggaccct
     2821 ggattgctga aactggagag ctgtccttcc ttgtcagcag caaaggagcc tcagcatgat
     2881 cctgaaggag cagccatctc cttagaagcc actgaggaga ctgttgtaag tggaagccta
     2941 gaaggcctca gtgaacaagc gcgggcttca gactcagacg cgaagtgcat aagttcagac
     3001 aaggcaaccg ttatggaaga acaagagagt actcatgaaa ttttcaaaag caaagattct
     3061 agaaatgtgg agtcagctac tgagtgtcag ttagcaacac tgggccccaa ccctctgtgc
     3121 tcatcagcac ttcctgtgaa tctaagcagt catcaagatg tagtgtcaac accctggata
     3181 aatgatgtca gatttccagg aagacattct gtcctacaac tgcagaaccc tgaaacttgt
     3241 gaaatattta aaagagaaaa aaacatgggg gtgttccaga agcccttagg gttgttgata
     3301 ccccacagat actgcaaact tcattttaac acattgcgtg gctgtgagcg agcacagtgc
     3361 aagtttgtcc atgtgcctga gcagggggat gagaagatct gcatggatgt gtttaggaaa
     3421 tacataagtg tcaatgagca gcgtttgctg catcgagcag catacatatt tctggagtac
     3481 tacagaaagt ttcccccagg gatacacttc agtttacaag tgctaaatga ccttttgatt
     3541 tctttactca agcattgttt attgaaagaa gtcttccagg tagtgcagct cagcataatg
     3601 gctaaaatgc tgcctgctct gaaaatatta ctaaaaatat ttgagtatgt ggcagctatg
     3661 aagttgagga atgctgtacc tgctttaatt gagatttttt gcaagttcat tgaagctggg
     3721 atggtacctg acccagagca cttgaactat attgttaagc ttttacatca agcacaggca
     3781 tcccaacaag aaatatctgc agttctgcaa gccaaatcca ggttgcgagt gaggcagctg
     3841 aaaaagaact ggaagtgtga cttagactca gccttgagtg aagtagagac ttgtaaagaa
     3901 aaaagtgact ggaccaaatt gggaaacctg tacattagca taaagatgag ttgtgaagaa
     3961 tttgcagatc tgcagagatt ctgtgcttgt gttgctgaga cgctcacaga agattacaaa
     4021 gaagagaggc caggcgttcc tttttgtgaa tttgctgaaa cagttagcaa agatccacag
     4081 tacagtgagg tggataagac tttgttggga aggatcggaa taagtgcggt gtacttctat
     4141 cacagactgt tgctgtgggc caagggaagg aaggtcttag atatattata tgagctaaaa
     4201 atacatttca caagtttaaa aggacttaca ggacctgaaa aagaagcacc aagatgtcaa
     4261 attgtaaatg ttgcagcaga gatttttatc aaaagtggga gcctagatgg tgccatttgg
     4321 gtcctaaggg aatcggaatg gataatcaac acaccacttt ggccttgtga tagaatggat
     4381 gtgcttaatc ggcataattt gctctgtacc attgcacatg aaatcttggg caagaatctt
     4441 tacaaacaaa catttgaggt cttacggaat ctaccaagct ttcagaattc tcaagaaatg
     4501 atgggggttt cccagtccag ccttcttttt aatgaacttc tggatgcctg tatagaaagt
     4561 aacagtcttg gcatatcgtc ttctgtagca gagttcatgg ttgccaagag catccctatt
     4621 gacttttcct ttctcaggag actcatcact tccttaggaa ggagttgttt gtggctcaaa
     4681 gccagagccc actacaaaag tgctctttca ctgggttgct acccaccatt agagggaaac
     4741 ttacaccgga aacttctcct ggttccttcg tatctatctg agattgaaat gcttttagct
     4801 atggaaatat ttctggtgtc caatgctagt ggcattcaga gtgcaggaat gggagcgccc
     4861 acacaggtgc tgcagattgt cctgaaaaga tgtgaagaaa gcaaatctcg aagcaaggat
     4921 gaatatcaag ctgcagtaga aagattggtc atggctgctc gaatatcgga ccccaagctt
     4981 ttcattaagc acatgactgt caatattaac aaggagcagg tgtacagtct ggagcactgt
     5041 tctgctttga aatggctgaa agagaatatg aagtgggctg gaaaggtttg gcttttcact
     5101 aaccattagt aaagggttgt tgttgcattt tctttttaag ttcaaataat cattgttgaa
     5161 aataaaagaa taaaaat
//
