LOCUS       NM_001291155            1940 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus translocase of outer mitochondrial membrane 34
            (Tomm34), transcript variant Tom34a, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001291155 XM_006500066
VERSION     NM_001291155.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1940)
  AUTHORS   Lo,J.C., Jamsai,D., O'Connor,A.E., Borg,C., Clark,B.J.,
            Whisstock,J.C., Field,M.C., Adams,V., Ishikawa,T., Aitken,R.J.,
            Whittle,B., Goodnow,C.C., Ormandy,C.J. and O'Bryan,M.K.
  TITLE     RAB-like 2 has an essential role in male fertility, sperm
            intra-flagellar transport, and tail assembly
  JOURNAL   PLoS Genet 8 (10), e1002969 (2012)
   PUBMED   23055941
REFERENCE   2  (bases 1 to 1940)
  AUTHORS   Terada,K., Ueno,S., Yomogida,K., Imai,T., Kiyonari,H., Takeda,N.,
            Yano,M., Abe,S., Aizawa,S. and Mori,M.
  TITLE     Expression of Tom34 splicing isoforms in mouse testis and knockout
            of Tom34 in mice
  JOURNAL   J Biochem 133 (5), 625-631 (2003)
   PUBMED   12801914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB869739.1, AK017699.1 and BM937584.1.
            
            On Mar 27, 2014 this sequence version replaced XM_006500066.1.
            
            Transcript Variant: This variant (Tom34a) contains an alternate 5'
            terminal exon and it thus differs in the 5' UTR and 5' coding
            region, compared to variant Tom34b. The encoded isoform (a, also
            known as Tomm34a) has a distinct N-terminus and is the same length
            as isoform b.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018278.1, AK075873.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BB869739.1         2-57
            57-1922             AK017699.1         2-1867
            1923-1940           BM937584.1         18-35               c
FEATURES             Location/Qualifiers
     source          1..1940
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 84.6 cM"
     gene            1..1940
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /note="translocase of outer mitochondrial membrane 34"
                     /db_xref="GeneID:67145"
                     /db_xref="MGI:MGI:1914395"
     exon            1..257
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..1060
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /note="isoform a is encoded by transcript variant Tom34a;
                     mitochondrial import receptor subunit TOM34; translocase
                     of outer membrane 34 kDa subunit"
                     /codon_start=1
                     /product="mitochondrial import receptor subunit TOM34
                     isoform a"
                     /protein_id="NP_001278084.1"
                     /db_xref="CCDS:CCDS71187.1"
                     /db_xref="GeneID:67145"
                     /db_xref="MGI:MGI:1914395"
                     /translation="MAPKVSDSVEQLRAAGNQNFRNGQYGEASALYERALRLLQARGS
                     ADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYA
                     LAYVDYKTVLQIDNSVASALEGINRITRALMDSLGPEWRLKLPPIPVVPVSAQKRWNS
                     LPSDNHKETAKTKSKEATATKSRVPSAGDVERAKALKEEGNDLVKKGNHKKAIEKYSE
                     SLLCSSLESATYSNRALCHLVLKQYKEAVKDCTEALKLDGKNVKAFYRRAQAYKALKD
                     YKSSLSDISSLLQIEPRNGPAQKLRQEVNQNMN"
     exon            258..357
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     exon            358..510
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     exon            511..680
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     exon            681..828
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     exon            829..955
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1923
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1903..1908
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /note="hexamer: ATTAAA"
     polyA_site      1923
                     /gene="Tomm34"
                     /gene_synonym="2610100K07Rik; TOM34"
                     /note="major polyA site"
ORIGIN      
        1 gtctggcccc gcccctcagg gccggtccac agtgggcctt aaaggcacgc agccctagct
       61 tccgggtgga agctgttgcg caccacttag ctgggaagtg cgttgctccc tgtttcccag
      121 cccacccgag atggccccca aagtctcgga ttccgtggaa cagctccgcg ctgccggcaa
      181 ccagaacttc cgcaatggcc agtacggcga agcctcggcg ctgtacgagc gcgcactgcg
      241 gctgctgcag gcgcgaggtt ctgcagaccc cgaagaagaa agtgttctgt actccaaccg
      301 tgcagcgtgc tacttgaagg atgggaactg cacagattgc atcaaagatt gcacttccgc
      361 gctggccttg gttcccttca gcatcaagcc cttgctgcgc agagcatctg catatgaagc
      421 cctggagaag tacgccctgg cctacgttga ctataagact gtgctgcaga tcgataacag
      481 tgtggcatcc gccctggaag gcatcaacag aataaccaga gctctcatgg actccctggg
      541 acctgagtgg cgcctgaagc tgccccctat ccctgtggtg cctgtttcag cccagaagag
      601 atggaattcc ttgccttcag ataaccacaa agagacagct aaaaccaaat ccaaagaagc
      661 cacagctacg aagagcagag tgccttctgc tggggatgtg gagagagcca aagctctgaa
      721 ggaagaaggc aatgaccttg taaagaaggg caaccataag aaagctattg agaagtacag
      781 tgagagcctc ttgtgtagta gcctggagtc tgccacatac agcaacagag cgctctgtca
      841 cctggtcctg aagcagtaca aggaggcagt aaaggactgc acagaagccc tcaagctgga
      901 tgggaagaat gtaaaggcgt tttacagacg ggctcaagcc tacaaggcac tcaaggacta
      961 taagtcaagc ctttcggata tcagcagcct cctacaaatt gaacccagga atggccctgc
     1021 acagaagtta cggcaggaag ttaaccagaa catgaactaa accgtagagg gcaacaggga
     1081 ccctgaactt gaccttccca gagaagccag ggcctccctt gcatctgccc caatgcccag
     1141 catgccgcca agggagtgca aaatcaaccc cactttgact ccttggagag gtagcagcct
     1201 ttcacctgac acattttact tgttcagatt aagtccatta cagacaagca caggactctt
     1261 tttttttttc ttcttttttt tttccagaaa ggtccccact agaggttttt gttttgtttt
     1321 atttttaatt taaaaaagcg tgacgccaac agccctggcc tcattcgctt gcttctgcct
     1381 ggcccttgtc aacacagtcc ttggcaactg tccctgaccc agatatgcac agactgggtg
     1441 cctgtgactt cctctgccgc catagctctg cagttcacct gagtgctgac aggctagaag
     1501 tgcttgctcg tccgcagcca cagcggcctg ttgagctggt tctccaaggc tgcctgccat
     1561 ctcctcgagg agacagctgc tgtctgcacc ctgtccttga cacagtgtcc tgtgttgagc
     1621 cccagtgcct ttagtccagg ccctttgtgg gaaggcagag cctaaccctt ggaggctctg
     1681 tgttgttgcc ttctgtctga gctacctacg atgttcaaag agcccagatt cctcctgcaa
     1741 tggggagaga ggcctccttg agattagtgt ccctccagtc tgagcaggaa cttaaccttt
     1801 tcccccatag cagcagcccc tcgggctcct ttgttttgtt ttgttttgtt aatatgttgg
     1861 agttaattga actgatttta ttgaagtgtg tgttgctgtt gcattaaaag gttttcttct
     1921 ataaaaaaaa aaaaaaaaaa
//
