LOCUS       NM_177805               6434 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus TOG array regulator of axonemal microtubules 1
            (Togaram1), transcript variant 2, mRNA.
ACCESSION   NM_177805 XM_001478538 XM_896986 XM_922989 XM_923034
VERSION     NM_177805.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6434)
  AUTHORS   Maggipinto,M.J., Ford,J., Le,K.H., Tutolo,J.W., Furusho,M.,
            Wizeman,J.W., Bansal,R. and Barbarese,E.
  TITLE     Conditional knockout of TOG results in CNS hypomyelination
  JOURNAL   Glia 65 (3), 489-501 (2017)
   PUBMED   28063167
  REMARK    GeneRIF: This study reveals that the cell-specific loss of TOG in
            oligodendrocytes severely reduced myelination in the CNS.
REFERENCE   3  (bases 1 to 6434)
  AUTHORS   Das,A., Dickinson,D.J., Wood,C.C., Goldstein,B. and Slep,K.C.
  TITLE     Crescerin uses a TOG domain array to regulate microtubules in the
            primary cilium
  JOURNAL   Mol Biol Cell 26 (23), 4248-4264 (2015)
   PUBMED   26378256
REFERENCE   4  (bases 1 to 6434)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159632.2 and AC159621.2.
            
            On or before Aug 1, 2009 this sequence version replaced
            XM_001478538.1, XM_923034.2, XM_922989.2, XM_896986.2, NM_177805.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC172117.1, SRR1660815.220619.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2287              AC159632.2         149544-151830
            2288-2444           AC159632.2         160497-160653
            2445-2579           AC159632.2         161971-162105
            2580-2876           AC159632.2         164385-164681
            2877-3139           AC159632.2         166248-166510
            3140-3378           AC159632.2         167130-167368
            3379-3476           AC159632.2         170195-170292
            3477-3572           AC159632.2         176347-176442
            3573-3748           AC159632.2         179308-179483
            3749-3902           AC159632.2         180694-180847
            3903-4056           AC159621.2         160444-160597       c
            4057-4162           AC159621.2         156781-156886       c
            4163-4398           AC159621.2         156095-156330       c
            4399-4557           AC159621.2         154497-154655       c
            4558-4684           AC159621.2         151966-152092       c
            4685-4803           AC159621.2         150252-150370       c
            4804-4993           AC159621.2         146535-146724       c
            4994-5213           AC159621.2         143854-144073       c
            5214-5300           AC159621.2         142805-142891       c
            5301-6434           AC159621.2         140632-141765       c
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 27.21 cM"
     gene            1..6434
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /note="TOG array regulator of axonemal microtubules 1"
                     /db_xref="GeneID:328108"
                     /db_xref="MGI:MGI:2684313"
     exon            1..2287
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..5566
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /note="isoform 2 is encoded by transcript variant 2;
                     protein FAM179B; crescerin-1; TOG array regulator of
                     axonemal microtubules protein 1; family with sequence
                     similarity 179, member B"
                     /codon_start=1
                     /product="TOG array regulator of axonemal microtubules
                     protein 1 isoform 2"
                     /protein_id="NP_808473.2"
                     /db_xref="CCDS:CCDS49075.1"
                     /db_xref="GeneID:328108"
                     /db_xref="MGI:MGI:2684313"
                     /translation="MAAAPSELLPLPPPATPGSYRLLSRCRPYAPGTDGRRSGGTMRG
                     EKNYYCRGAAGDHGSCPATPSPLASTLLLPAEAVSTSWSGPGSGLSGGDEEETRLLQL
                     LRTAPDPSEAFQALQAALPRRGGRLGFPRRKEALYRALGRVLVEGGSEEKRLCLQLLS
                     DVLRGQGEAGQLEEAFSLALLPQLVVSLREDNPALRKDALQILHICLRRSSGQVLRTL
                     IQGLESPDARLRASTALLLPILFTPEDLLQGLDLTEVIISLARKLGDQEMEEESETAF
                     SSLQQIGERLGQERFHSYISRLPSALRRHYNRRLESQYGSQVPYYLELEASGFSEDAA
                     PCVVNLSSSNLKFEIIPQELHARLLDQEDYKNRTQAVEELKQLLGKFNPSSTPHASLV
                     GFISLLYNLLDDSNFKVVHGTLQVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVI
                     KQEYMKIFLKLMKEVGPQRVLSLLLENLKHKHSRVREEVVNICICSLLTYPSEDFDLP
                     KLSFDLAPALVDSKRRVRQAALEAFAVLASSMGSGKTNVLFKAVDTVELQDNGDGVMN
                     AVQARLARKTLPRLTEQGFVEYAILMPSSAQGRSSHLAHGADTDWLMSGNRTQSAHCY
                     CGDHTRDSMQLYGSYSPTICTRRVLSAGKGKNKLPWENEQPGVMGENQTSNSKDIKDT
                     EQFSAHDLIPSPKLKPSQGMPASDDLCFSKKRSSRNLFQSSRDFNSESVPTCGAGNTA
                     DLQTNLPGKCGQLGLSQIGCRTGSVGSDLQFLGTANGHQDKVYASIDFGSKTQQTFGS
                     QSERTSSYSGSNASPGSFILPSYPLASPRTSPKHTSPLSVAPKKSQDNSISFSNSWPL
                     KSFEGLSKPSPQKKLANQKSSDPTGENFQEKTTAVQLTPALVRSPSSRRGLNGTKPVP
                     PIPRGINLLPDKADLSTMGHMKKQPDDIWKSEKDNLTIDLSELNFRDKDLDQEEMHSS
                     LRSLRNSAAKKRAKLSGSSSTSDVDSPDSAMKLELTIDSPSRASSPNISSYSESGVYS
                     QESLTSSLSTTPQGKRIMSDIFPTFGSKPCSTRLSSAKKTSHAAEQSPSAGFTRSSNL
                     QQISSFDFTSTNTLSEDSVVIVGKGVFGNPNSAPTTCSQPVISSVESEDTFPVKPSIE
                     PPSGVYGRAVQHNAPLYPEVENDKDTKVSIAKSTYEKMRQKRKEEKELLDAKDCERKE
                     TNPWERIKHLGSEKMTSENEPSSGVIPQYKERMSSVTHSPEIMDSLELRPFSKPDIAL
                     TEALRLLADEDWEKKMEGLNFVRCLAAFHSDLLNTKLHETTFAVVQEVKNLRSGVSRA
                     AVVCLGDLFTYLKKSMDQELDSAVRALLHKAGESNTFIREDVDKALKAMVNNVTPARA
                     VTSLINGGQSHLHIAVRRCTAQHLADVVECMDPERISSGTKDMADRLLPAAAKFAQDS
                     SQETRYYGRKMLFLMMGHPNFEKLLEKYIPSKDLPYIKESVKNLRLKGLGEIPLDTAS
                     AKGRRSHPGSVGNTRSSSVSRDAFSSSEREVTEVREVPRKSAPRNSLESAEYIKVITG
                     LLNAKDFRDRINGIKQLLSDTENNQELVVGNIVKIFDAFKSRLHDSNSKVNLVALETM
                     HKMIPLLRDNLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVHALSQHVDNYLLLQPF
                     CTKAQFLNGKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTHSGSLPGA
                     GGNIRTATAKLSKALFTQMGQNLLNQAASQPPHIKKSLEELLDVTVLSEL"
     exon            2288..2444
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            2445..2579
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            2580..2876
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            2877..3139
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3140..3378
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3379..3476
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3477..3572
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3573..3748
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3749..3902
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            3903..4056
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4057..4162
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4163..4398
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4399..4557
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4558..4684
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4685..4803
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4804..4993
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            4994..5213
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            5214..5300
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     exon            5301..6434
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6413..6418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /note="hexamer: AATAAA"
     polyA_site      6434
                     /gene="Togaram1"
                     /gene_synonym="A430041B07Rik; C130034K06; Fam179b"
                     /note="major polyA site"
ORIGIN      
        1 gtggtggccc tggttacgcc gggtggcgcc tgtggggtcc caggctcagc gggggccatt
       61 ttgccggagg ctggctccgg gagtggaagg cccgagcggc ctggcagctg accggagccg
      121 ttccttctct tcctctgcag ctcggggctt ggagaggaac tggaaggctg ggcttcatcc
      181 agccctccca agacggcaat ggttccctcc agctctcgct acctgacgac cctccatggc
      241 ggccgcgcct tccgagctgc tcccgctgcc gcctcctgcg acccctggtt cctatcgcct
      301 cctgagccgc tgtcgtcctt acgccccagg gactgatggt cgtcgatccg ggggcaccat
      361 gagaggcgag aaaaactatt actgccgtgg ggctgccggg gatcatggct cctgccccgc
      421 gacgccgtcg cctctggcct cgaccctcct gttaccggcg gaggctgttt caactagctg
      481 gtccgggcct ggaagtgggc tctcgggcgg agatgaggag gagactcggc ttcttcaact
      541 cctgcgcacc gcaccggatc cttccgaggc gttccaggct ttgcaggctg ccttgccgcg
      601 gcgaggcggc cggcttggct ttccccgccg caaggaagcc ttatatcggg cgctgggccg
      661 agtgcttgtg gaaggcggca gtgaggagaa gaggctctgc ttgcagcttc tctcggacgt
      721 tcttcggggt cagggcgagg cgggtcagct ggaagaggcc ttcagtttag cgcttttgcc
      781 tcagctcgtt gtctcgttac gagaagataa ccctgcccta cggaaagatg cgctgcagat
      841 cctgcatatt tgtcttaggc gtagttctgg gcaggtcctg cgaactctca tccaaggcct
      901 ggaaagtcca gatgcccggc ttagagcttc cactgcgctg ttgctcccta tcttgttcac
      961 tcctgaggat ttgttgcagg gtttggatct cactgaagta ataatatctc tggcccgaaa
     1021 gcttggcgat caggagatgg aagaagaatc cgagacagcc ttctcttcac ttcaacaaat
     1081 tggagaacga cttggtcaag agaggtttca ctcctacatc tcgcgtttgc cttctgcact
     1141 gaggaggcac tacaatcgcc gcctggagtc ccagtatgga agtcaggttc cttattattt
     1201 ggagctagaa gcctccgggt tttctgaaga tgctgccccg tgtgtagtga atctttccag
     1261 tagcaatctt aaatttgaga ttattcccca ggaactccat gcaagactgt tggatcagga
     1321 agattataaa aacaggactc aggctgttga agaactaaag cagttgctgg gaaaatttaa
     1381 cccaagttcg acccctcatg ctagtctcgt tggtttcatt agcttattgt ataacttgct
     1441 agacgattcc aatttcaaag tggtccatgg cacacttcaa gttctccatt tgctggtcat
     1501 tcgcctggga gagcaggtgc aacagttctt gggaccagtt atagcggctt ctgtgaaagt
     1561 gctggcagac aacaagttgg tgatcaagca ggagtacatg aaaatcttcc taaagctaat
     1621 gaaagaagtg ggtcctcagc gggtgctttc tttgctcctg gaaaacctta aacataagca
     1681 ttccagagta cgggaggaag tagtgaacat ttgcatctgt tccctcctga cctaccccag
     1741 tgaggatttt gacttaccca aactgtcctt tgatcttgct ccagctcttg tggatagcaa
     1801 acgcagggta cgccaggcag ctttagaggc ctttgctgtt ttggcatcat caatgggctc
     1861 aggtaaaacc aatgttcttt ttaaagctgt agatactgtt gaattgcagg ataatggcga
     1921 tggggtgatg aatgccgtgc aggcccgatt ggccagaaaa actcttccac ggctaacaga
     1981 acagggattt gtggagtatg caatactcat gccgtcttcg gcccagggca ggtcaagcca
     2041 tttggcacat ggagcagata cagactggct tatgtccggt aacaggactc agagtgcaca
     2101 ctgctactgt ggtgaccaca ccagggacag catgcaactt tatggatcct acagtccaac
     2161 tatctgtacc cgaagggttt taagtgctgg aaaggggaaa aataaactgc catgggaaaa
     2221 tgagcagcct ggagtcatgg gagaaaacca gacctccaat tccaaggaca ttaaagatac
     2281 cgagcagttt tcagctcatg accttatccc gtctccaaaa ttaaagccct ctcaaggaat
     2341 gccagccagt gatgatttat gttttagcaa aaaaaggtca tcaagaaact tatttcagag
     2401 tagtcgggac tttaactcag agtcagttcc tacatgtggt gctggtaata ctgcagatct
     2461 tcagacaaat cttcccggga aatgtgggca gcttggattg tcacagatag gttgtagaac
     2521 tggcagtgtg ggttctgact tacagttttt ggggacagcc aatggccatc aagataaagt
     2581 atatgctagc attgattttg gcagtaagac acagcaaaca tttggtagtc aatcagaacg
     2641 aacttcttca tactctggtt caaatgcaag tccaggatcc ttcatccttc catcctatcc
     2701 tctcgcatca cctcgaacta gtccaaagca cacatctcct ctttctgtag caccaaagaa
     2761 gtcgcaagat aattccatta gtttctcaaa ttcttggcct cttaagagct tcgaaggact
     2821 gtcaaagcca agtccacaga aaaagcttgc caaccagaaa tcatctgacc ctacaggaga
     2881 aaattttcaa gaaaaaacta ctgcagttca acttacacct gccttggtgc gatcaccttc
     2941 ttcccgaaga ggcctaaatg ggaccaaacc tgttcctccc ataccaaggg ggataaacct
     3001 cttgcctgat aaagctgact taagcacaat gggacacatg aagaaacagc ctgatgatat
     3061 ttggaaaagt gaaaaagata atcttacaat tgatctttca gaattgaatt tcagagataa
     3121 agatttggat caggaagaga tgcacagctc tcttaggtcc cttcgaaata gtgcagctaa
     3181 gaaaagagcc aaactcagtg gcagcagcag cacctctgat gttgacagtc ccgactctgc
     3241 catgaagctt gagctgacca ttgactcccc gtcccgagct tcctctccaa acatcagctc
     3301 ttacagtgaa agtggagtgt atagccaaga atcgttgacc tcttctcttt ctacaacgcc
     3361 tcaggggaag agaataatgt cagacatatt tccaacattt ggatcaaaac cttgctcaac
     3421 aaggctttct tctgcaaaga aaacctccca tgctgctgaa cagagtccca gtgcaggatt
     3481 tactaggtca tcaaatttac agcagatttc cagttttgac ttcacatcta caaacacctt
     3541 atcagaagac tcagtagtaa ttgttggaaa aggtgtattt ggaaatccaa attcagcacc
     3601 aacaacttgc agccagccag taatatcctc tgtggaaagt gaggacacgt ttccagtgaa
     3661 accaagcatt gaaccgccat caggggttta tggaagagca gtccagcata atgctccact
     3721 atatcctgag gttgaaaatg acaaagatac taaagtttct attgcaaaat ctacttatga
     3781 aaaaatgaga caaaagagaa aggaagaaaa agaacttctt gatgctaaag attgtgaacg
     3841 gaaagagacg aatccctggg aacgaataaa gcatctagga agcgagaaaa tgacatccga
     3901 gaatgaacca tcttctggag tcattccaca atataaagaa cgaatgtctt ctgtcactca
     3961 cagtccagag ataatggatt cattagaact acggccattt tccaaaccag acatagcact
     4021 tacagaagcc ttgcggcttt tagccgatga ggactgggag aagaagatgg agggactgaa
     4081 ttttgtccga tgcttagctg ctttccattc cgacctgttg aacacaaaat tgcatgaaac
     4141 aacctttgca gtagttcaag aggtgaaaaa tttacgctct ggagtgtccc gtgctgctgt
     4201 ggtgtgctta ggtgaccttt ttacatacct gaaaaagagc atggatcaag aactagatag
     4261 tgcagtaagg gctttgttgc acaaagctgg agaatcgaat accttcataa gggaagatgt
     4321 tgacaaggca ttgaaagcta tggttaataa tgtaactcct gcacgtgcag tcacttctct
     4381 catcaatgga ggacaaagcc atctgcacat tgcagtaaga agatgtacag cccagcactt
     4441 ggcagatgta gtagaatgta tggacccaga gcgaatttca tctggaacaa aggatatggc
     4501 tgatcgttta ttgcctgctg ctgctaagtt tgctcaagac agctcacaag aaaccaggta
     4561 ttatggtcga aagatgcttt tcctcatgat gggtcatcct aactttgaaa aactacttga
     4621 aaagtatatc ccatctaaag atttgccata tattaaagaa tccgttaaaa atttacggct
     4681 aaagggcttg ggagagatac ctctagacac agcatcagca aaaggaaggc gatctcatcc
     4741 tggcagtgtt gggaacacaa ggtcatcctc tgtttctcga gatgctttca gttcttctga
     4801 gagggaagta actgaagttc gagaagtccc cagaaaatca gctcctcgta attccttaga
     4861 aagtgctgag tatattaaag tcataacagg attattaaat gcaaaagact ttcgtgatcg
     4921 tattaatggg attaaacaac ttttatcaga cactgaaaac aatcaggagc ttgttgtagg
     4981 caacattgtg aagatctttg atgcttttaa gtctcgactt catgattcta acagcaaagt
     5041 gaatctggtg gctctagaaa caatgcacaa aatgattcct ttacttagag acaacttgtc
     5101 tcctataatc aatatgctga ttcctgcaat tgtggataac aacctgaatt ccaagaatcc
     5161 aggcatctat gctgcagcca caaatgttgt tcacgcactg agtcaacatg tagacaatta
     5221 cttgcttcta cagccatttt gcacaaaagc tcagtttcta aatggaaaag caaaacaaga
     5281 tatgacagaa aagcttgctg atattgttac ggagctttat caaaggaagc ctcatgccac
     5341 agaacagaaa gtgctggtgg ttttatggca cctcttaggg aatatgacac atagtggctc
     5401 cctgcctgga gctggtggaa atattcgaac agccacagct aaattatcaa aagcactttt
     5461 tacccagatg ggtcagaatc tactaaatca ggctgcatct caaccaccac atatcaaaaa
     5521 gagtttagag gaattacttg atgtgacagt tttaagtgaa ttatgagttt ttgatgaact
     5581 agttatgatg aacaatttac ttgatgacag atgaaatctt tttaaactta cattttttat
     5641 tttgagtgcc tgaatttcat gtccagtaaa ttaagtcagg ggctatgttt atttgcagcc
     5701 tacctgtgag tacagatctg tcttgatagc catcacatga aaacctaaaa taatgaatat
     5761 aaactaatat gaaatataaa atgatatgaa atccatggca cctgggatga actaaatttt
     5821 aaatattttt tgggaaaaat cctgttcatt tgcactattc tatagaaact gcaatttgtt
     5881 gccccatatg tacaattaga tttgtaatta aaaatatact ttttattatg taatcatgtt
     5941 ctgctatgtc tcattactct gtcttgtttt atgaagtgga agaaacgtca tttaactgtt
     6001 atcacgaagt ctgcgtgctg tttgtgaata acatgtttaa accatctgct aatgtgatta
     6061 tgcagtatta gcttcctata gctgctgtgt tactatgata tatttgctaa acttttgggt
     6121 ttgatcatct gcacaattgt gaaatttaag agttataata aagcatgatg accaaagctt
     6181 agaaaacatt aaacatttga atgcacgttc aagaaacgtg ttgaatgtaa ctttattttt
     6241 gtgtgcaaac actaaatttt taatttgtgt atgtctgtcc atttataaag gtgttatttt
     6301 gctgcccagt tgtgtaattc tcaaaaatag tgccaggtct tctatagttt ttctcagaat
     6361 tcttgggctt acaagtactg tatgcatctt aaagaagaaa aggaatgttt aaaataaaag
     6421 gatttatttc tgta
//
