LOCUS       NM_031176               9569 bp    mRNA    linear   ROD 08-NOV-2023
DEFINITION  Mus musculus tenascin XB (Tnxb), mRNA.
ACCESSION   NM_031176
VERSION     NM_031176.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9569)
  AUTHORS   Kamada H, Emura K, Yamamoto R, Kawahara K, Uto S, Minami T, Ito S,
            Matsumoto KI and Okuda-Ashitaka E.
  TITLE     Hypersensitivity of myelinated A-fibers via toll-like receptor 5
            promotes mechanical allodynia in tenascin-X-deficient mice
            associated with Ehlers-Danlos syndrome
  JOURNAL   Sci Rep 13 (1), 18490 (2023)
   PUBMED   37898719
  REMARK    GeneRIF: Hypersensitivity of myelinated A-fibers via toll-like
            receptor 5 promotes mechanical allodynia in tenascin-X-deficient
            mice associated with Ehlers-Danlos syndrome.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9569)
  AUTHORS   Sumioka T, Iwanishi H, Okada Y, Miyajima M, Ichikawa K, Reinach PS,
            Matsumoto KI and Saika S.
  TITLE     Impairment of corneal epithelial wound healing is association with
            increased neutrophil infiltration and reactive oxygen species
            activation in tenascin X-deficient mice
  JOURNAL   Lab Invest 101 (6), 690-700 (2021)
   PUBMED   33782532
  REMARK    GeneRIF: Impairment of corneal epithelial wound healing is
            association with increased neutrophil infiltration and reactive
            oxygen species activation in tenascin X-deficient mice.
REFERENCE   3  (bases 1 to 9569)
  AUTHORS   Liu Y, Zhou X, Hu N, Wang C and Zhao L.
  TITLE     P311 regulates distal lung development via its interaction with
            several binding proteins
  JOURNAL   Mech Dev 163, 103633 (2020)
   PUBMED   32682987
REFERENCE   4  (bases 1 to 9569)
  AUTHORS   Ohki S, Oka K, Ogata K, Okuhara S, Rikitake M, Toda-Nakamura M,
            Tamura S, Ozaki M, Iseki S and Sakai T.
  TITLE     Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in
            Palatal Epithelium Regulate Tenascin-C Expression in Palatal
            Mesenchyme During Soft Palate Development
  JOURNAL   Front Physiol 11, 532 (2020)
   PUBMED   32581832
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9569)
  AUTHORS   Okuda-Ashitaka E, Kakuchi Y, Kakumoto H, Yamanishi S, Kamada H,
            Yoshidu T, Matsukawa S, Ogura N, Uto S, Minami T, Ito S and
            Matsumoto KI.
  TITLE     Mechanical allodynia in mice with tenascin-X deficiency associated
            with Ehlers-Danlos syndrome
  JOURNAL   Sci Rep 10 (1), 6569 (2020)
   PUBMED   32300146
  REMARK    GeneRIF: Mechanical allodynia in mice with tenascin-X deficiency
            associated with Ehlers-Danlos syndrome.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9569)
  AUTHORS   Ikuta T, Sogawa N, Ariga H, Ikemura T and Matsumoto K.
  TITLE     Structural analysis of mouse tenascin-X: evolutionary aspects of
            reduplication of FNIII repeats in the tenascin gene family
  JOURNAL   Gene 217 (1-2), 1-13 (1998)
   PUBMED   9795100
REFERENCE   7  (bases 1 to 9569)
  AUTHORS   Burch GH, Bedolli MA, McDonough S, Rosenthal SM and Bristow J.
  TITLE     Embryonic expression of tenascin-X suggests a role in limb, muscle,
            and heart development
  JOURNAL   Dev Dyn 203 (4), 491-504 (1995)
   PUBMED   7496040
REFERENCE   8  (bases 1 to 9569)
  AUTHORS   Julian J, Chiquet-Ehrismann R, Erickson HP and Carson DD.
  TITLE     Tenascin is induced at implantation sites in the mouse uterus and
            interferes with epithelial cell adhesion
  JOURNAL   Development 120 (3), 661-671 (1994)
   PUBMED   7512897
REFERENCE   9  (bases 1 to 9569)
  AUTHORS   Hofer U and Chiquet-Ehrismann R.
  TITLE     Tenascin variants: ligands and expression
  JOURNAL   Prog Clin Biol Res 383B, 455-464 (1993)
   PUBMED   7509489
REFERENCE   10 (bases 1 to 9569)
  AUTHORS   Saga Y, Yagi T, Ikawa Y, Sakakura T and Aizawa S.
  TITLE     Mice develop normally without tenascin
  JOURNAL   Genes Dev 6 (10), 1821-1831 (1992)
   PUBMED   1383086
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT573030.3 and AK136535.1.
            
            [WARNING] On Mar 8, 2024 this sequence was replaced by NM_031176.3.
            
            On Jan 29, 2011 this sequence version replaced NM_031176.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB235155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-370               CT573030.3         32530-32899
            371-2203            CT573030.3         33050-34882
            2204-2319           CT573030.3         35232-35347
            2320-2476           CT573030.3         40567-40723
            2477-2740           CT573030.3         40851-41114
            2741-3034           CT573030.3         45279-45572
            3035-3325           CT573030.3         46916-47206
            3326-3616           CT573030.3         47583-47873
            3617-3949           CT573030.3         50595-50927
            3950-4273           CT573030.3         51319-51642
            4274-4564           CT573030.3         52137-52427
            4565-4864           CT573030.3         54284-54583
            4865-5152           CT573030.3         55742-56029
            5153-5443           CT573030.3         56161-56451
            5444-5764           CT573030.3         57380-57700
            5765-6091           CT573030.3         57799-58125
            6092-6415           CT573030.3         73429-73752
            6416-6703           CT573030.3         74905-75192
            6704-6982           CT573030.3         75507-75785
            6983-7264           CT573030.3         76585-76866
            7265-7573           CT573030.3         77678-77986
            7574-7909           CT573030.3         78296-78631
            7910-8032           CT573030.3         78881-79003
            8033-8176           CT573030.3         79118-79261
            8177-8296           CT573030.3         79436-79555
            8297-8440           CT573030.3         79661-79804
            8441-8571           CT573030.3         79894-80024
            8572-8704           CT573030.3         80147-80279
            8705-8832           CT573030.3         80378-80505
            8833-9557           AK136535.1         3930-4654
            9558-9569           CT573030.3         81799-81810
FEATURES             Location/Qualifiers
     source          1..9569
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.24 cM"
     gene            1..9569
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /note="tenascin XB"
                     /db_xref="GeneID:81877"
                     /db_xref="MGI:MGI:1932137"
     exon            1..370
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            371..2203
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2319
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2476
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2740
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            2741..3034
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3325
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            3326..3616
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            3617..3949
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            3950..4273
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            4274..4564
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            4565..4864
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            4865..5152
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            5153..5443
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            5444..5764
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            5765..6091
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            6092..6415
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            6416..6703
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            6704..6982
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            6983..7264
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            7265..7573
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            7574..7909
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            7910..8032
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8033..8176
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8177..8296
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8297..8440
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8441..8571
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8572..8704
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8705..8856
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8857..8953
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            8954..9115
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            9116..9279
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
     exon            9280..9569
                     /gene="Tnxb"
                     /gene_synonym="Tn-mhc; Tnx"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcagctc agtgcacccc gtctattctg accatcctgg tgttgcttgg cttagccaga
       61 gcaggcccat tctctcctcg gtctaatgtg acacttccgg ccccacggcc ccctcccaag
      121 cccggtggtc cttcttctca gctgtacgag catactgtgg aaggaggaga gaagcaggtg
      181 gtgttcaccc atcgcattaa cctgcccccg tcagccggct gcggctgtcc cccgggctct
      241 gagcccccgg tgcctgcttc agaggtgcag gccctgaggg tccgcctgga gatcctggag
      301 gagctggtaa aagggcttaa ggagcactgc acaggaggat gctgtcccac tgcggcccaa
      361 gctggcacag gccagactga cgtgcgcagc ctctgcagcc tccacggtgt ctttgacctg
      421 agccgctgcg cctgttcctg tgagcctggc tggggtggac ccacctgctc agaccctacg
      481 gacacaaaga cgcccacctc atcgccgccc tccaagtcct gtcccgaaga ctgcaacgac
      541 cagggacgct gcgtccgagg acgctgcgtg tgcttccccg gctacagtgg ccccagctgt
      601 agctggccct cttgccctgg agattgtcag gggcgcgggc gctgcgtgaa gggcgtgtgc
      661 gtgtgtcgcg cgggcttctc aggccctgac tgcagccagc gctcttgccc tcgcaactgc
      721 aaccagagag gacgctgcga ggaaggacgc tgcgtgtgtg accccggcta ctccggtgag
      781 gactgtgggg tgcggagctg tcccagggga tgcagccaaa gaggccgctg cgagaacggc
      841 ctctgcgtgt gcaaccccgg ctactctggc gaggactgtg gggtgcggaa ctgtcccagg
      901 ggctgcagcc agaggggtcg ctgcgaggac ggccgctgtg tgtgcgatcc cggctatagt
      961 ggcgaagatt gcagcatgag gacctgccca tgggactgtg gcgacggagg gcgctgcgtg
     1021 gacggtcgct gcgtgtgctg gcccgggtac tcgggcgaag actgtagcac gcggacgtgc
     1081 ccgcgtgact gccgtggccg gggccgctgc gaggacgggg aatgtatctg tgacgcaggc
     1141 tacagtggcg acgactgcgg tgtgcggagc tgccccgggg actgtaacca aaggggccac
     1201 tgtgaggatg gccgctgcgt gtgctggccc gggtatactg gagcggactg tagcacgcgc
     1261 gcctgcccac gggactgcag gggccgcggg cgctgcgagg atggcgtgtg cgtgtgccat
     1321 gcgggctaca gcggcgagga ctgcggggtg cgcagctgcc ccggggactg tcgcggccgt
     1381 gggaactgcg agagcggccg ctgcgtgtgc tggcctgggt acacaggccg agactgtggc
     1441 acgcgtgcct gccccggtga ctgtcgtgga cgcgggcgct gcgtggacgg ccgctgcgtg
     1501 tgcaatccgg gcttcactgg cgaggactgc gggagccgtc ggtgtcctgg ggactgtcgc
     1561 ggacacggcc actgcgagaa cggcgtgtgc gtgtgcgctg tgggctactc tggcgacgac
     1621 tgcagcactc gcagctgtcc cagcgactgc agaggccgcg gccagtgcct gaatgggctc
     1681 tgcgagtgcg acgaaggcta ctcgggtgag gactgtggca taagacggtg tccccgcgat
     1741 tgcagccagc acggcgtgtg tcaggatggc ttgtgcatgt gccacgcagg ctatgcgggc
     1801 gaagactgca gcattcgcac ctgcccggcc gactgtcgcc ggcgtggccg ctgtgaggac
     1861 gggcgctgtg tgtgcaaccc aggctacacc gggcccgcat gtgccactcg aacctgtcca
     1921 gctgattgtc gtggccgtgg gcgctgcgtg cagggagtgt gcatgtgcta cgttggctac
     1981 agcggtgagg actgtggaca ggaagagcct cctgctagtg cctgccctgg gggctgtggg
     2041 ccgcgggaac tgtgccgcgc cggacaatgc gtgtgtgttg agggctttcg aggcccagac
     2101 tgtgccatcc agacgtgccc aggtgactgt cgcagcaggg gagagtgtat ccagggcaga
     2161 tgcgtctgcc aagaaggcta cgctggggac gactgcgggg aagagatacc agccatccag
     2221 aacatgagga tgcatcttct agaggagaca acagtccgga cagagtggac acgagctccc
     2281 ggtcctgtgg atgcctatga aatccagttt atccccatga ccgagggggt gagtccacca
     2341 ttcacagctc gggtgcccag ctctgcctca gcctatgacc agcgaggact ggcgcctgga
     2401 caggactacc aggtcactgt tcgtgctcta cgagggacca gctggggtcc tcctgcctct
     2461 aagaccatca ctaccatgat cgatggtcct caggacctcc gggtggtagc tgtgaccccg
     2521 accacactgg atcttagctg gctgcgcccc caggctgagg tggaccgatt tgtggtgtcc
     2581 tatgtcagtg ctggaaacca aagggtgcga ctggaagttc cccctgaggc agacaggact
     2641 cagctaaccg atctgatgcc tggtgtggag tatgtggtga ctgtcactgc agaaagaggc
     2701 catgcagtca gctacccagc ttctatcagg gcgaatacag acagggctca ggaacagcct
     2761 gggaagccat cagtccagcc acgcctgggt gaactgacag tgacaggcct gacctctgat
     2821 tccctgctcc tgcactggac tgtcccagag ggggagtttg actccttcct gatccagtac
     2881 aaggacaaag acgggcccca ggcgatatcc gtggagggac cccagcgttc tacacccatc
     2941 tcaggcttgg aaccaggacg caagtacaaa tttatcctgt atggactcat cggcaagaag
     3001 aggcatggcc cacttatggc tgaagccaag atcttgattc agagtgaccc tgacccagga
     3061 tccccacccc gcctgggaga gctatgggtg acagacccca ctccacactc attgcacctc
     3121 tcctggactg ttctcggagg ccagttcgac tccttcgtgg tccagtacag agacaaggaa
     3181 ggccagcccc gtgtggtacc tgtggagggg cctgatcgct cagtggtgat ctccccactg
     3241 gaccccaatc gcaagtacag gttcactctg tttgggattg ccaataagaa gcggtacggg
     3301 ccccttactg ctgatggcac tactgctgca gagacgaaag aggagtcctc agagccgccc
     3361 cgcctcggcg aactgactgt gactggtgtg accccagact ccctgcgcct gtcctggaca
     3421 gtggcccggg gtcccttcga ctcctttgta atcctttaca aggatgcaca gggccagccc
     3481 cagagtgtac ccatcgaagg tgatgagaat gaggtcactg tccccggcct ggagtccaac
     3541 aggaagtata agatgaacct ctacgggctt cgtggcaggc agcgtgtggg gccggtatca
     3601 gtggtggcca aaactgcccc accagatgtt gtagaccagc ccctcagccc cccagagccc
     3661 agcacagagg ccccagagcc ccccgagaag ccactcctga gagagctgat cgtgacagac
     3721 accacaccca actccctgag cctctcctgg acagtctccg agggacagtt tgaccagttc
     3781 gtgatccagt acaagaacgg ggatgggcag cccaaggtgg tgcgggtgcc aggacacgag
     3841 gaccaggtca ccatctccgg cctggagcca gaccacaagt ataagatgaa cctgtatggc
     3901 atccatagtg gccagcgtgt gggccccgtg tctgttgttg gtgtgacagc tgcagaggaa
     3961 gaacccccca gccccacaga gcccagcaca gaggcgccag aacccactga ggagccgctc
     4021 ctgggagagc tgacagtgac aggatcgtcc ccagactccc tgagcctctc ctggaccgtc
     4081 ccccagggag actttgactc cttcactgtc cagtacaaga gcagtgatgg gcggccccag
     4141 gtgatgcgtg tcgggggcca ggagagggag gtcatcgtga gagacctgga tcctgggcac
     4201 aaatacaaga tgaacctgta tggactccat gaggggcatc gtgtgggccc tgtgtccact
     4261 gtgggcacaa ccgacaaaca accagaagaa aagccccccc ttgagccacg cctggaggag
     4321 ttgacagtga ctggtgtaac ccccaattct gtgagcctct cgtggatagt tcctgaggga
     4381 cagtttgact ccttcgtggt ccagtaccag gacagggatg ggcagccccg ggaggtacca
     4441 ctgacagcag aacagcgtga ggtcactgtc cttgacttgg accctgcaag aatatacaaa
     4501 atgaacttct acgggctaca cggtagacga cgtgtgggcc ccctctccgt gtcagcaatg
     4561 acagcaccag ctccagccac cgaggcctcc aagctgctcc cagaaccacg actgggggaa
     4621 ctaacagtga cagatgtgac cccggactca gtgggcctcc tgtggactgt ccctgagggt
     4681 gaattcgact ccttcacggt ccagtacaag gacagggatg gccagcccca cgtggtgtct
     4741 gtggcagcag acctacggga ggtcaccatc ccaggcctgg agccctctcg caagtacaag
     4801 ttcctgctct ttggggtcca agatgggaaa agacgcagcc aggtctctgt agaggcgaag
     4861 acagctaccc atgatgacac cagcccaggg gcccctcccc gccttggaga gctgtgggtg
     4921 acggatccta ccacggactc tctgcgccta tcctggacag ttcccgaggg ccactttgac
     4981 tcttttgtgg tccagttcaa ggacaaaagt gggcccaggg tggtgccagt aaagggtcaa
     5041 gagcggacag ccactatcac ggccctggat gctggccgca agtacagatt cctcctctat
     5101 gggcttctgg gaaggaaacg ctttggcccc ctcactgcag agggcataac agagcccacg
     5161 aatgctgcgg accacacaaa atctcgactg ggagaggaac tgcgggtgac tggtgtgact
     5221 caaaactccg tggacctctc ctggacagtc tccgagggcc agtttgactc ctttgtggtc
     5281 cagtacaagg acagggatgg gcagtcccag gtggtgcctg tggacggaag ccatagagag
     5341 gttagagtct ctggtctaga cccaggtcgc aggtataagc tgctactcta cggcctccga
     5401 gacagcaagc gtgtgggtcc cctttcagtc attgctgtga ccgaccccag agaaacaaca
     5461 gaagcttgga cagaggtccc cacaacttca actcctgcag ctgtgccccg cctcggggag
     5521 ctgagagtgg aggaagccac gcctcacagc ctgcatctct cctgggtggt gactgaggga
     5581 gaatttaact ccttcgaggt ccagtacact gacagagatg ggcaactcag agtggccagt
     5641 acagagggtg accagactga cattaccctt actggcctgg aatcgaacca cagatacctg
     5701 ataaccctat atggcttcca tgatgggcag cctgtaggct ctgctcaaat tgaggccctg
     5761 acagtgccgt gggaggaaga agaggaggaa gaggagtcca cagagccacc caccatgact
     5821 cctgagccca ggccacaact gggagagctg accgtgacag atgccacccc tgactctctg
     5881 agcctttcct ggacagtccc cgagggacag tttgaccagt tcgtgatcca gtacaagaac
     5941 ggggatgggc agcccaaggt ggtgcgggtg ccagggcatg aggaccaggt caccatctct
     6001 ggcctggagc cagaccacaa gtacaagttg aacctgtatg gcatccacag tggtcagcgt
     6061 tttggccccg tgtctactgt tggggtgaca gctgcagtgg aagagccccc cagccccaca
     6121 gagcccagca tagaggcccc agagcccact gaggagccac tcctgggaga gctgacagtg
     6181 acaggatcgt ccccagactc tctgagcctc tcctggaccg ttccccaggg agactttgat
     6241 tccttcactg tccagtacaa ggacagtgat gggcggcccc aggtgatgcg tgtcgggggc
     6301 caggagaggg aggtcatcgt gagagacctg gatcctgggc gcaagtacaa gatgaacctg
     6361 tatgggctcc atgaggggcg tcgtgtgggt cccgtgtcga ctgtgggtgt gactgcctct
     6421 ctgaccacag agccccccat agagccccgc ctgggagagc tggctgcagt agaagtgact
     6481 tccagtacag tgcacctgtc ctggactgtg gcccagggcc ccttcgactc cttcctggtc
     6541 cagtacaagg acacacaggg gcagccccag atggtgcctg tgagtggaga cctgggtgag
     6601 gtcaccgtct caggtttgga gccagcccga aagtacaagt ttctactctt tggactcaag
     6661 gatgggaagc gccatggccc tgtctccaca gaagcaaaga ctgtctctga tgcaaagctg
     6721 cttcctcgtc ttggggagct caccgtgaca gacacgaccc aaaactccgt gggtctctcc
     6781 tggactgttc ctgagggtga attcgactct ttcttagtcc agtacaagaa caggggaggg
     6841 caggtccagg tcgtgcctgc agcagcagac caacgtgagg tcaccatctc cagcctggag
     6901 cccaatagaa aatacaggtt cctgctcttc ggcctcatag gcctcaaacg gctggggcct
     6961 gtctccgtgg agggcaccac ggctcccgtg gagaagacac cacagccccg cctcggtgaa
     7021 ctgtcagtga cagaggagac ctctgactcc atgcacctct cttggtctgt ggcccagggt
     7081 ccctttgact ccttcctggt ccagtacaag gacagggatg ggcagctcca gacggtgtcc
     7141 ttggctgcag accagcgaga ggtcaccata gagggtctac agccaggcag gaaatacaag
     7201 ttcctgctct atgggctcac tggagggaag cgcctgggac ccatctctgc cttgggagtg
     7261 acagcctcag aagttgacat atcagcccca gaccacactg agccccctca tgctcccggc
     7321 ctggggacgc tggcagtgac agaggcaacc ccagactccc tgcgactctc ctgggctgtg
     7381 gctcgtggcc cctttgactc ctttgtggtc cagtaccagg acacagagaa tgaaacccag
     7441 gccctgcttg ttgatggaga ccaggacaaa gtcctcatct caggcctgga acccaaaact
     7501 tcctacaagt tcttcctcta tggcctccgt gaagggacac gccacggacc tgtgtctgta
     7561 gagggcacca cagatccagt tcctgctggt cagggcccag gggaccccgg gccccgcctg
     7621 tcccagctct cagtttcaga tgtgaccacc agttctctgc ggctaaactg ggaagccccg
     7681 cttggggcct ttgactcttt cctgctacgc tttggggtcc ccctactgag taccctggag
     7741 cagaatcctc gcactctgca acagcgagag cttatggtgc caggcgtgcg gcgatccgcc
     7801 atgctccggg acctgcgtcc tgggaccctg tatagcctta ctctgtatgg gctgcgtggg
     7861 ccacacaagg cagacagcat ccagggcact gcccgcacac tcagcccagt tctggagagc
     7921 ccccgggacc tgcaattcag cgacatcggg gaaacatcag ccaaagtcaa atgggtgccg
     7981 ccaacgtcca gggtggacag cttcaaaatc tcctaccagc tagcagatgg aggagagcca
     8041 caaagtgtgc aggtggatgg ccggacccag acccagatcc tccaagggct gattccagac
     8101 actcgctatg aggtgactgt ggtctccgtc cgtggctttg aggaaagcga gcctctcaca
     8161 ggcttcctca ccacagtgcc tgatggtccc acccagctac gggcattgaa cttgactgac
     8221 ggatctgccc ttctacactg gaaacccccc cacaaaccag tggacaaata tgacgtcgag
     8281 gtcgaatccc ctggggcccc accccttcag gcctcagcac ctggcagcgc tgtggactac
     8341 ccactgactg acctggcact cgacaccaat tacacagcca ccgtgcgtgg tctccggggt
     8401 cctaacttca cctccccagc cagcataacc ttcaccacag ggttaaagcc cccccaggac
     8461 ttggaggcca aggaagtgac tcctcgcacg gccctgctca cttggactga gcctgaagtc
     8521 ccacccacag gctacctgct cagctttgac acccctggag gacagattca ggaaatcctg
     8581 cttccagcag gaaccacctc gcacaggctt ctgcgcctct tcccctccac cttctacagt
     8641 gcccagctgc gggccatctg gggcgagagc cttacacctc ccgtgctcac ttcctttact
     8701 actggtgggc tgcggatccc cttcccccgg gactgtgggg aggagctgaa gaatgggccc
     8761 agtgcctcaa agaccaccac catcttcctc aatggcaacc gtgagcggcc tttggatgtg
     8821 ttctgtgaca tggagactga tggaggtggt tggctggtgt tccagcgccg catggatgga
     8881 cagacggact tctggagaga ctgggaggag tacgcccatg gttttgggaa catttccggg
     8941 gaattctggc tgggcaacga ggccctgcac agcctaacac aggctggaga ctattctctg
     9001 cgtgtggacc tgcgggccgg aaaggaagcc gtgttcgccc agtatgactt cttccgtgta
     9061 gactcagcaa aggagaacta ccgcctacac cttgagggct accatgggac tgcaggcgac
     9121 tctatgagct accacagtgg cagtgtcttt tctgcccgtg atcgagaccc caacaacttg
     9181 ctcatctctt gcgctgtctc ttatcgtggg gcttggtggt acaggaactg tcactacgcc
     9241 aacctcaatg ggctctatgg gagcacagtg gatcaccagg gagtgagctg gtaccactgg
     9301 aagggcttcg agttctctgt gcccttcacg gaaatgaagc tgcgacccag aaacttccag
     9361 gtccccacca ggggcacctg agcctgctgc ccacctcact cacaccccgg tatgactgcc
     9421 gagcactgag gggttgtgcc cagagaagag ccagcatgcc acaccaagga ggccttctct
     9481 gccacaatct cacagcacca tgtttacagg gggggagggg aggggaaatg gagcaataaa
     9541 ggagaaactg aggcactagg ctcatccta
//
