LOCUS       NM_001364032            4858 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus transportin 2 (importin 3, karyopherin beta 2b)
            (Tnpo2), transcript variant 4, mRNA.
ACCESSION   NM_001364032 XM_017312647
VERSION     NM_001364032.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4858)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4858)
  AUTHORS   Han,Y., Xiong,Y., Shi,X., Wu,J., Zhao,Y. and Jiang,J.
  TITLE     Regulation of Gli ciliary localization and Hedgehog signaling by
            the PY-NLS/karyopherin-beta2 nuclear import system
  JOURNAL   PLoS Biol 15 (8), e2002063 (2017)
   PUBMED   28777795
  REMARK    GeneRIF: essential for Hedgehog pathway activation; mediates
            ciliary translocation of Gli proteins
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4858)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4858)
  AUTHORS   Lo,J.C., Jamsai,D., O'Connor,A.E., Borg,C., Clark,B.J.,
            Whisstock,J.C., Field,M.C., Adams,V., Ishikawa,T., Aitken,R.J.,
            Whittle,B., Goodnow,C.C., Ormandy,C.J. and O'Bryan,M.K.
  TITLE     RAB-like 2 has an essential role in male fertility, sperm
            intra-flagellar transport, and tail assembly
  JOURNAL   PLoS Genet 8 (10), e1002969 (2012)
   PUBMED   23055941
REFERENCE   5  (bases 1 to 4858)
  AUTHORS   Young,J.C., Major,A.T., Miyamoto,Y., Loveland,K.L. and Jans,D.A.
  TITLE     Distinct effects of importin alpha2 and alpha4 on Oct3/4
            localization and expression in mouse embryonic stem cells
  JOURNAL   FASEB J 25 (11), 3958-3965 (2011)
   PUBMED   21840941
REFERENCE   6  (bases 1 to 4858)
  AUTHORS   van der Giessen,K. and Gallouzi,I.E.
  TITLE     Involvement of transportin 2-mediated HuR import in muscle cell
            differentiation
  JOURNAL   Mol Biol Cell 18 (7), 2619-2629 (2007)
   PUBMED   17475777
  REMARK    GeneRIF: Early in muscle differentiation, HuR is localized to the
            nucleus of myoblasts by active Transportin 2 (TRN2)-mediated
            import.
REFERENCE   7  (bases 1 to 4858)
  AUTHORS   Bulfone,A., Carotenuto,P., Faedo,A., Aglio,V., Garzia,L.,
            Bello,A.M., Basile,A., Andre,A., Cocchia,M., Guardiola,O.,
            Ballabio,A., Rubenstein,J.L. and Zollo,M.
  TITLE     Telencephalic embryonic subtractive sequences: a unique collection
            of neurodevelopmental genes
  JOURNAL   J Neurosci 25 (33), 7586-7600 (2005)
   PUBMED   16107646
REFERENCE   8  (bases 1 to 4858)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 4858)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY149255.1, BY233571.1, AK155760.1, BQ771085.1, AK029774.1,
            CB246525.1 and AC163703.4.
            
            On Jun 6, 2018 this sequence version replaced XM_017312647.1.
            
            Transcript Variant: This variant (4), as well as variants 5 and 6,
            encodes isoform 2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.200468.1,
                                           SRR1660811.146967.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BY149255.1         3-25
            24-392              BY233571.1         3-371
            393-901             AK155760.1         373-881
            902-1606            BQ771085.1         70-774
            1607-2286           AK029774.1         478-1157
            2287-2819           CB246525.1         1-533
            2820-3198           AK155760.1         2830-3208
            3199-4858           AC163703.4         103718-105377       c
FEATURES             Location/Qualifiers
     source          1..4858
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 41.51 cM"
     gene            1..4858
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /note="transportin 2 (importin 3, karyopherin beta 2b)"
                     /db_xref="GeneID:212999"
                     /db_xref="MGI:MGI:2384849"
     exon            1..85
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            86..240
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2805
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /note="isoform 2 is encoded by transcript variant 4;
                     karyopherin (importin) beta 2b; transportin-2; karyopherin
                     beta-2b"
                     /codon_start=1
                     /product="transportin-2 isoform 2"
                     /protein_id="NP_001350961.1"
                     /db_xref="CCDS:CCDS90431.1"
                     /db_xref="GeneID:212999"
                     /db_xref="MGI:MGI:2384849"
                     /translation="MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDF
                     NNYLIFVLTRLKSEDEPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASS
                     LIRATIGILITTIASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSEL
                     LDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHL
                     FALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACE
                     FWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIK
                     PRFHKSRTVTLTHEAERPDSSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELL
                     PHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKAL
                     VRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEA
                     CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPL
                     IQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYT
                     QHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQ
                     SSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEM
                     QPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSL
                     RNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHG
                     FKDQVGEENWQQFSEQFPPLLKERLAAFYGV"
     exon            241..316
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            317..466
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            467..573
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            574..707
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            708..789
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            790..912
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1031
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1092
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1258
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1411
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1637
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1809
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1896
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1897..2004
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2005..2163
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2251
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2252..2350
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2446
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2447..2522
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2622
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2623..2697
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2825
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            2826..4858
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4835..4840
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /note="hexamer: AGTAAA"
     polyA_site      4858
                     /gene="Tnpo2"
                     /gene_synonym="1110034O24Rik; IPO3; Knpb2b; Kpnb2b; TRN2"
                     /note="major polyA site"
ORIGIN      
        1 attccctgcc tctggctccc tccttccgcg cgagcctctg gagaagctgc agcacttagg
       61 cgccgccgct gcctcccggg gcctgaactc cagcgaccca gcgctgatcc aggctcctac
      121 ccctgcagtt cgccttgcgc catggactgg cagccagacg agcagggcct gcagcaggtc
      181 ttgcagcttc tcaaagactc gcagtcgccc aacacagcta ctcagcgcat tgtgcaggat
      241 aaacttaaac aactcaacca gtttcctgac tttaacaact acctgatctt tgtcctgacc
      301 agactcaaat cagaagatga gccaacccgc tctctgagtg gcctcatcct caagaacaat
      361 gtgaaggcgc attaccagag cttcccgcct cctgtggctg acttcatcaa acaggagtgt
      421 ctcaacaaca ttggcgatgc ctcctctctc atcagagcca ccatcggcat tctcatcacc
      481 accatcgctt ccaagggtga gctgcagatg tggccagagc tgctgcctca gctgtgcaac
      541 ctgctcaact cagaggatta taatacctgt gagggagcct ttggagccct acagaagatc
      601 tgtgaagact cctcggagct tttggatagt gatgctctca acaggcccct caacatcatg
      661 atccctaaat tcctgcagtt tttcaagcac tgcagcccta agatccggtc ccacgccatc
      721 gcctgtgtga accagttcat catggaccgg gcccaagcgc tgatggacaa cattgacact
      781 ttcattgagc acctgtttgc cttggctgtg gatgatgacc ctgaggtgag aaagaacgtg
      841 tgccgggccc ttgtgatgct tttggaagtg cgaattgaca ggctcatccc tcacatgcac
      901 agcatcatcc agtacatgct gcagaggacc caggaccatg atgagaacgt ggccctggag
      961 gcctgtgagt tctggctgac gctagccgag cagcccatct gcaaggaagt cctggcctct
     1021 catctggtcc agttgatccc tatcctcgtg aatgggatga agtactctga aattgacatc
     1081 atccttctta agggggatgt ggaggaggac gaggcggtac ctgacagtga gcaggacatc
     1141 aagccccggt tccacaagtc acgcacagtg acattgactc acgaggctga gcggcctgat
     1201 agctctgagg atgctgagga cgacgatgat gacgacgctt tgtcggactg gaatctgagg
     1261 aagtgctctg cagctgcgct ggatgtcctt gccaatgtct tccgggagga actgttgccc
     1321 cacctacttc ccctgctcaa gggcctccta ttccaccctg agtgggtggt caaagagtca
     1381 gggatcctgg tgctgggcgc catcgctgag ggctgcatgc agggaatggt gccctatcta
     1441 cctgagctga tcccacacct catccagtgc ctgtcagata agaaggctct agtacgctcc
     1501 attgcctgct ggacgctgag ccgctatgcc cactgggtag tcagccagcc acctgacatg
     1561 cacctcaagc ctctgatgac ggagctgctc aagcgtatct tggatggcaa taagcgggtt
     1621 caggaggcag cctgcagtgc atttgctacc ctggaggagg aggcatgcac ggagctggtg
     1681 ccctacctca gctatatcct tgacactctc gtttttgcct ttggcaaata ccagcataag
     1741 aacctgctca tcctctatga tgccattggc accctggccg actctgtggg ccaccacctc
     1801 aatcagccgg agtacattca gaagctgatg cctccgctga tccagaagtg gaatgagctc
     1861 aaggacgaag acaaggacct cttccccctg ctggagtgcc tatcatctgt ggccactgcc
     1921 ctgcagagtg gcttcctgcc ctactgcgag cctgtctacc agcgctgtgt taccctggta
     1981 cagaagacac tggcccaggc catgatgtat acacaacacc ccgaacaata tgaggcccca
     2041 gacaaagact tcatgattgt tgcgttggac ctgcttagtg gcttggctga gggcctgggt
     2101 ggccacgtgg agcagctggt agctcggagt aacatcatga cattgctctt ccagtgtatg
     2161 caggattcca tgcctgaggt ccggcagagc tcctttgccc ttctgggaga ccttaccaaa
     2221 gcctgcttta tccacgtcaa gccctgtatc gctgagttca tgcctattct gggtaccaac
     2281 ctgaaccctg agttcatctc tgtctgcaac aatgctacct gggccattgg ggagatctgc
     2341 atgcagatgg gggcagagat gcagccttat gtgcagatgg tcctcaacaa cctggtggag
     2401 atcattaaca ggcccaacac acccaagacg ctgctggaaa acacagccat caccatcggc
     2461 cgcctgggct acgtgtgccc gcaggaggtg gcacccatgc tgcagcagtt catccggcct
     2521 tggtgcacgt cccttaggaa catccgggac aacgaggaga aggattctgc cttccgaggc
     2581 atctgcatga tgattggtgt caatcctggg ggtgttgtgc aggactttat tttcttctgc
     2641 gatgctgtag cctcctgggt gagcccgaag gatgaccttc gggacatgtt ttataagatc
     2701 ctccatggct tcaaagacca agttggggag gagaactggc aacagttctc agagcagttc
     2761 ccacctctgc tcaaggagag gctggcagcc ttctatgggg tctaggtgaa cgtggagacc
     2821 accaggtttt tgtctgcgtc atcgtcggag ggtgtgctgg gaatgtgctg cttccagaag
     2881 tcactgtgcc ctggtcgagg ggggttaggg aggagtcagt gggacctaaa tccaggtgca
     2941 acgcagtctg tgcatctgtc catctgtcgg tccacttgcc ccaccgggcc tgatgagtgg
     3001 gcaggtgggt ggggactcca ttctcatcct acaaataggg aggggggtgg gacttcttgg
     3061 tgggcaagag ttctctgggc tctaatctgg gtcatctcgg gcagcccact tgggccagct
     3121 atgtgggagg gaggaatcca taaggcctac cgaatccggt gtcagataag gcaagggaat
     3181 tacaggtggg gaggggggtt ccttgtagag aagcatacac tcacatgtac acatgtggac
     3241 acacgcatgt gcgggcacca cagccagcta ggctgggcca aacgccccac catttcctcg
     3301 actgcatgga gacagtagaa ttagtgaacc cccaaattat gcctatggcc tctgtgtacc
     3361 ttgcatctag agtataagaa gcttctgctg ttctgccaaa attggcggga attggggggg
     3421 ctgggaggtt tgggggacct cagctgggct cccggggcca agggaggagg gtggtcattt
     3481 tggggctgcc atctcagcac tggctcactt ggacctgctc catacacttc ctgccagctt
     3541 catggcagcc tcatgtagtg tgtccccatc gttgtcacat cctagccagc agcagagtgg
     3601 ggatcattgg agcagctgag actggcttga ggctaccctg ttcctgtgct ccaaaggtaa
     3661 ttaaaggcac aggcctggga ctagttttcc ttgagaaagc taataatggt tgccagagct
     3721 gctttcctgg atctcttgaa acagctttaa ggatagttca gttctctgca cctgagaacc
     3781 ccattctcaa gagctggggt aacagcatgt gatggtgaga acaaaggacg aagtttactg
     3841 ggtccagcaa gatttgaaag cttggaggag cagggtgtac ccagggcctc aaactttgtc
     3901 ccttttggga cttacgttta tcacagtgtc cgctggactc agaccacgcc agattggtac
     3961 actgactcaa aacctttgaa gaaatttgtt ggcgatgcca tcggggtggg aggggcttcc
     4021 cgagaggaga ggggcatgat tatttccaga ttagctgtgg aaatgagtct tgtaaggtcc
     4081 ctgaggttta tcctccatcc ctttctttgc ttcctacata tttgggagcc cattatatct
     4141 tgggctttga ctggagttct gcattttagg gcctgctcca tcatccctcc aaggacttgg
     4201 acctttatcc tttccaggcc ttgtgtcctt tcttaagtag ggtcaggccc tgcctctgtt
     4261 cccagggaca cttagtgcac attccataac tcagctactg gtccccatcc cctccagcct
     4321 gaaacttgag caggtctctg gaagccattt gtaggaaaaa aaaatttttt ttaaagaaaa
     4381 ataccattag ctttctggta attccacttc ttaggagcat cctctgctgg gtcttggggt
     4441 gtattgatgg attgactatc tgatgtagtt gtggcccctc tttgtccaat ggggaggggg
     4501 agggagttcc aactaccttc aggaaacggg agcctgattc ttgtatttcc ctttttttat
     4561 tttattttat tttattattt ttttaaaaga aattatttaa ttttttaatt tattttttag
     4621 ttggtttttg cacaatgaag tttgagtttc ttaacctccc ttgtccgggg ctgctgacat
     4681 ggactgacct tgatctgtag ccctccctgc tgccattccc ctgagtcttt attaccatca
     4741 cccctgggct cccaggtcta tccatctgtt actgtgctgt gctggggact agcgcctagg
     4801 tggcgtgaga ttccactcgt gtagaacttt gttgagtaaa ggtcagtttc ttgtgaaa
//
