LOCUS       NM_009407                431 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus transition protein 1 (Tnp1), mRNA.
ACCESSION   NM_009407
VERSION     NM_009407.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Ho,U.Y., Feng,C.A., Yeap,Y.Y., Bain,A.L., Wei,Z., Shohayeb,B.,
            Reichelt,M.E., Homer,H., Khanna,K.K., Bowles,J. and Ng,D.C.H.
  TITLE     WDR62 is required for centriole duplication in spermatogenesis and
            manchette removal in spermiogenesis
  JOURNAL   Commun Biol 4 (1), 645 (2021)
   PUBMED   34059773
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Gustafson,E.A., Seymour,K.A., Sigrist,K., Rooij,D.G.D.E. and
            Freiman,R.N.
  TITLE     ZFP628 Is a TAF4b-Interacting Transcription Factor Required for
            Mouse Spermiogenesis
  JOURNAL   Mol Cell Biol 40 (7), e00228-19 (2020)
   PUBMED   31932482
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 431)
  AUTHORS   Alrahel,A., Movahedin,M., Mazaheri,Z. and Amidi,F.
  TITLE     Study of Tnp1, Tekt1, and Plzf Genes Expression During an in vitro
            Three-Dimensional Neonatal Male Mice Testis Culture
  JOURNAL   Iran Biomed J 22 (4), 258-263 (2018)
   PUBMED   29397043
  REMARK    GeneRIF: Tnp1, Tekt1, and Plzf have essential roles in
            spermatogenesis and can be expressed during organ culture of
            testis; with this system, genes can be induced only at the
            molecular level and not beyond meiosis.
REFERENCE   4  (bases 1 to 431)
  AUTHORS   Barral,S., Morozumi,Y., Tanaka,H., Montellier,E., Govin,J., de
            Dieuleveult,M., Charbonnier,G., Coute,Y., Puthier,D., Buchou,T.,
            Boussouar,F., Urahama,T., Fenaille,F., Curtet,S., Hery,P.,
            Fernandez-Nunez,N., Shiota,H., Gerard,M., Rousseaux,S.,
            Kurumizaka,H. and Khochbin,S.
  TITLE     Histone Variant H2A.L.2 Guides Transition Protein-Dependent
            Protamine Assembly in Male Germ Cells
  JOURNAL   Mol Cell 66 (1), 89-101 (2017)
   PUBMED   28366643
REFERENCE   5  (bases 1 to 431)
  AUTHORS   Nakajima,R., Okano,H. and Noce,T.
  TITLE     JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during
            Spermatogenesis
  JOURNAL   PLoS One 11 (9), e0163466 (2016)
   PUBMED   27649575
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 431)
  AUTHORS   Shih,D.M. and Kleene,K.C.
  TITLE     A study by in situ hybridization of the stage of appearance and
            disappearance of the transition protein 2 and the mitochondrial
            capsule seleno-protein mRNAs during spermatogenesis in the mouse
  JOURNAL   Mol Reprod Dev 33 (2), 222-227 (1992)
   PUBMED   1418993
REFERENCE   7  (bases 1 to 431)
  AUTHORS   Vidal,S.M., Epstein,D.J., Malo,D., Weith,A., Vekemans,M. and
            Gros,P.
  TITLE     Identification and mapping of six microdissected genomic DNA probes
            to the proximal region of mouse chromosome 1
  JOURNAL   Genomics 14 (1), 32-37 (1992)
   PUBMED   1358796
REFERENCE   8  (bases 1 to 431)
  AUTHORS   Keime,S., Heitland,K., Kumm,S., Schlosser,M., Hroch,N., Holtz,W.
            and Engel,W.
  TITLE     Characterization of four genes encoding basic proteins of the
            porcine spermatid nucleus and close linkage of three of them
  JOURNAL   Biol Chem Hoppe Seyler 373 (5), 261-270 (1992)
   PUBMED   1627265
REFERENCE   9  (bases 1 to 431)
  AUTHORS   Lafuse,W.P., Brown,D. and Zwilling,B.S.
  TITLE     Assignment of the microtubule-associated protein 2 gene to mouse
            chromosome 1
  JOURNAL   Mamm Genome 3 (1), 48-51 (1992)
   PUBMED   1581633
REFERENCE   10 (bases 1 to 431)
  AUTHORS   Engel,W., Keime,S., Kremling,H., Hameister,H. and Schluter,G.
  TITLE     The genes for protamine 1 and 2 (PRM1 and PRM2) and transition
            protein 2 (TNP2) are closely linked in the mammalian genome
  JOURNAL   Cytogenet Cell Genet 61 (2), 158-159 (1992)
   PUBMED   1395729
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC048494.1 and BF152963.1.
            
            On Oct 2, 2007 this sequence version replaced NM_009407.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CN842524.1, BU938354.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-422               BC048494.1         1-422
            423-431             BF152963.1         1-9                 c
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 36.94 cM"
     gene            1..431
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /note="transition protein 1"
                     /db_xref="GeneID:21958"
                     /db_xref="MGI:MGI:98784"
     exon            1..175
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..204
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /codon_start=1
                     /product="spermatid nuclear transition protein 1"
                     /protein_id="NP_033433.1"
                     /db_xref="CCDS:CCDS35611.1"
                     /db_xref="GeneID:21958"
                     /db_xref="MGI:MGI:98784"
                     /translation="MSTSRKLKTHGMRRGKNRAPHKGVKRGGSKRKYRKSVLKSRKRG
                     DDASRNYRSHL"
     exon            176..427
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      407..412
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /note="hexamer: AATAAA"
     polyA_site      427
                     /gene="Tnp1"
                     /gene_synonym="Stp-1; Tp-1; TP1"
                     /note="major polyA site"
ORIGIN      
        1 ggccttgcaa agcccctcat ttcggcagaa agtaccatgt cgaccagccg caagctaaag
       61 actcatggca tgaggagagg caagaaccga gctcctcaca agggcgtcaa gagaggtgga
      121 agcaagagaa aataccggaa gagcgtcctg aaaagtagga aacggggcga tgatgcaagt
      181 cgcaattacc gatcccactt gtgatgcggc aatgagctct gccctggtgg tcttcaaaca
      241 acacggggca ggagcatgag gacatcagag ggggactgcc aaagagatct gaagttagac
      301 caaaagccaa agatcctatc agagtgggta aatgccagtc gtgacgaaat tcggaatgta
      361 tatgttggct gtttctcccc aacatctcaa taacattttg aaaacaaata aaattgtgaa
      421 aaacaaaaaa a
//
