LOCUS       NM_001081260            5781 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus tankyrase 1 binding protein 1 (Tnks1bp1), mRNA.
ACCESSION   NM_001081260 XM_619777
VERSION     NM_001081260.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5781)
  AUTHORS   Zhu,J., Ao,X., Liu,Y., Zhou,S., Hou,Y., Yan,Z., Zhou,L., Chen,H.,
            Wang,P., Liang,X., Xie,D., Gao,S., Zhou,P.K. and Gu,Y.
  TITLE     TNKS1BP1 mediates AECII senescence and radiation induced lung
            injury through suppressing EEF2 degradation
  JOURNAL   Respir Res 25 (1), 299 (2024)
   PUBMED   39113018
  REMARK    GeneRIF: TNKS1BP1 mediates AECII senescence and radiation induced
            lung injury through suppressing EEF2 degradation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5781)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5781)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   4  (bases 1 to 5781)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   5  (bases 1 to 5781)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   6  (bases 1 to 5781)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY023631.1, CB723061.1, CF733903.1 and BC058639.1.
            
            On Oct 3, 2007 this sequence version replaced NM_001081260.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC150947.1, SRR10223969.2644.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-317               BY023631.1         1-317
            318-846             CB723061.1         186-714
            847-1270            CF733903.1         247-670
            1271-4406           BC058639.1         323-3458
            4407-5781           BC058639.1         3551-4925
FEATURES             Location/Qualifiers
     source          1..5781
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.45 cM"
     gene            1..5781
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /note="tankyrase 1 binding protein 1"
                     /db_xref="GeneID:228140"
                     /db_xref="MGI:MGI:2446193"
     exon            1..101
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            102..214
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..5283
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /codon_start=1
                     /product="182 kDa tankyrase-1-binding protein"
                     /protein_id="NP_001074729.1"
                     /db_xref="CCDS:CCDS38166.1"
                     /db_xref="GeneID:228140"
                     /db_xref="MGI:MGI:2446193"
                     /translation="MKGSTLREGTAMASPLPQDMEEELAPVGSEPGDPRAKPPVKPKP
                     RGLPSKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGVSKRPLPFAPR
                     PSAEATAGGDVTQESGKEDAGKEDLPPLTPPARCAALGGVRKAPAPFRPSSERFAACT
                     VEEILAKMEQPRKEILASPDRLWGSRLTFNHDGSSRYGPRTYGAPCPREEDSKSPAKG
                     RSQEGTAEIPAECQEEHSKTPEERNLTSSPAMNGDLAKLACSEAPTDVSKTWVTSSAD
                     PVSEHGGSTSAVRLANISVPASESPRLSSRPSSPCHSQLSETQSPAASEASSICLPVT
                     PASPSAVLPAEPPGHSPSSELPAEAAPETLSPNSSPVETVSGHHSPEQPPVLLPQLLT
                     EGAELPDITRTFPCGEEAAARGHTESRPSSLAQRRFSEGVLQPPSQDQEKLGGSLATL
                     PQGQGSQSALDRPFGSGTESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEA
                     AEAAEADSWAVSGRGEGVSQVGPGTPPAPESPRKPISGVQGNDPGISLPQRDDGESQP
                     RSPALLPSTVEGPPGAPLLQAKENYEDQEPLVGHESPITLAAREAALPVLEPALGQQQ
                     PTPSDQPCILFVDVPDPEQALSTEEDVVTLGWAETTLPMTEAQEPCSVSPEPTGPESS
                     SRWLDDLLASPPPNSGSARRAAGAELKDRQSPSTCSEGLLGWAQKDLQSEFGVATDSH
                     HSSFGSSSWSQDTSQNYSLGGRSPVGDTGLGKRDWSSKCGQGSGEGSTREWASRHSLG
                     QEVIGIGGSQDESEVPVRERAVGRPAQLGAQGLEADAQQWEFGKRESQDPHSIHDKEL
                     QDQEFGKRDSLGSFSTRDASLQDWEFGKRASVSTNQDTDENDQELGMKNLSRGYSSQD
                     AEEQDREFEKRDSVLDIHGSRATAQQNQEFGKSAWFQDYSSGGGGSRVLGSQERGFGI
                     RSLSSGFSPEEAQQQDEEFEKKTPVGEDRFCEASRDVGHLEEGASGGLLSPSTPHSRD
                     GAARPKDEGSWQDGDSSQEITRLQGRMQAESQSPTNVDLEDKEREQRGWAGEFSLGVA
                     AQSEAAFSPGRQDWSRDVCVEASESSYQFGIIGNDRVSGAGLSPSRKSGGGHFVPPGE
                     TKAGAVDWTDQLGLRNLEVSSCVSSEGPSEARENVVGQMGWSDSLGLNNGDLARRLGT
                     GESEEPRSLGVGEKDWTSSVEARNRDLPGQAEVGRHSQARESGVGEPDWSGAEAGEFL
                     KSRERGVGQADWTPDLGLRNMAPGAGCSPGEPRELGVGQVDWGDDLGLRNLEVSCDLE
                     SGGSRGCGVGQMDWAQDLGLRNLRLCGAPSEVRECGVGRVGPDLELDPKSSGSLSPGL
                     ETEDPLEARELGVGEISGPETQGEDSSSPSFETPSEDTGMDTGEAPSLGASPSSCLTR
                     SPPSGSQSLLEGIMTASSSKGAPQRESAASGSRVLLEEEGLAAGAGQGEPQEPSRAPL
                     PSSRPQPDGEASQVEEVDGTWSLTGAARQNEQASAPPPRRPPRGLLPSCPSEDFSFIE
                     DTEILDSAMYRSRANLGRKRGHRAPAIRPGGTLGLSETADSDTRLFQDSTEPRASRVP
                     SSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRSRNRSAEEGEVTESKS
                     SQKESSVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKI"
     exon            215..845
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            846..915
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            916..2277
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            2278..4406
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            4407..4776
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            4777..4927
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            4928..5064
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            5065..5222
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            5223..5295
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     exon            5296..5747
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5722..5727
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /note="hexamer: AATAAA"
     polyA_site      5739
                     /gene="Tnks1bp1"
                     /gene_synonym="mKIAA1741; Tab182"
                     /note="major polyA site"
ORIGIN      
        1 gaggtgattc cagagacttg agagtttctg gccttcttgc tccgctcaga gtggacacct
       61 ctagtggggc tccctgaccc gagagggttg cctcaggagc tgcagggtgt gccctatgtg
      121 atgaaaggat ccactctcag ggaaggcaca gccatggctt ccccactgcc ccaggatatg
      181 gaggaggagc tggcgcctgt tggctccgag ccaggtgacc cacgagccaa gccccctgtc
      241 aagcccaaac cccggggctt gcccagcaag ccagctctgc ctgccaaacc cagcctcctg
      301 gtgcctgttg ggcctcgccc tcctcggggt cccctggctg agctgccttc tgcccggaag
      361 atgaacatgc tggcaggacc tcagccctat ggggtcagca agcgtcccct cccgtttgca
      421 ccaaggcctt cagctgaagc aaccgctgga ggagacgtta cccaagagtc tgggaaggag
      481 gatgctggga aagaagactt gccccctctc acacccccag ctcggtgcgc tgccctggga
      541 ggtgtgagga aggcccctgc ccctttccgt ccctcctctg agcggtttgc agcctgtaca
      601 gtagaagaaa ttttggccaa gatggagcag ccacggaaag agatcctggc cagccctgac
      661 cgcctctggg gctcccgcct cacttttaac cacgatggca gctctcgata tggccccagg
      721 acctatggtg ccccctgccc cagagaggag gatagtaagt cccctgccaa aggacggtcc
      781 caggagggga cagcagagat tcctgcagag tgccaggaag agcatagcaa gactcctgag
      841 gagaggaacc tcacttccag cccggcaatg aatggggacc tagctaaact ggcttgctct
      901 gaagcaccta ccgacgtttc caagacctgg gtcacctcaa gtgcagaccc tgtttcagag
      961 catggcggct ctaccagtgc agtccgcctg gctaacatct ctgtcccagc ctcggagtct
     1021 ccccggcttt caagccgccc gagttctccc tgccattctc aactttcaga aacccaaagt
     1081 cctgcagctt ctgaggcttc ttccatctgc ctccctgtga ctccagcctc ccccagtgca
     1141 gtcttgcctg ctgagcctcc cggccattct cctagctcag agttacctgc tgaggcagcc
     1201 ccagaaaccc tcagccccaa cagctctcct gtggagacag tctcagggca ccacagccca
     1261 gagcagcccc cagtcctctt gcctcaactc ctgactgagg gggctgagtt gccggacatt
     1321 acacgaacgt tcccctgtgg ggaggaggca gcagccaggg gtcacacgga atctcgtccc
     1381 agcagcctgg ctcagcgtcg tttctcagaa ggcgtgctcc agccacctag ccaggaccaa
     1441 gagaagctgg gaggctcgct ggctactctg ccccaaggtc aggggagcca atctgcttta
     1501 gatcgtccct tcggaagcgg gacagagtct aattggagct tgtcacagtc atttgagtgg
     1561 acctttccca caaggccctc aggtctgggc gtgtggcggc tggactcccc acctccatct
     1621 cccattacag aagccagtga ggccgcagag gctgctgaag ctgacagttg ggctgtatct
     1681 ggcagggggg aaggtgtgtc ccaggtggga ccaggaaccc caccagctcc agagagcccc
     1741 agaaagccta tttctggggt tcagggaaat gatccaggca tatccctacc ccagagagat
     1801 gatggagaga gtcagcctcg gtccccagct cttcttccct ctacagttga gggcccacct
     1861 ggagcaccct tactgcaggc aaaggagaac tatgaggacc aggagccact agtggggcac
     1921 gagtccccca ttactttggc tgcaagggag gcggccttac ctgtgctaga gccagcgctg
     1981 ggacagcagc agccaacacc ctctgaccaa ccctgcatcc tctttgtgga tgtgcccgat
     2041 cctgagcagg cattgtctac tgaggaggac gtggtgaccc taggctgggc ggagacgacc
     2101 ctgcccatga cagaggctca ggaaccctgt agtgtgtctc ctgagcctac aggccctgaa
     2161 agcagttctc gatggctgga tgacctccta gcatcaccac cacccaactc gggcagtgcg
     2221 cggcgggcag ctggagctga gctaaaggat agacagtcac caagcacctg ctctgaggga
     2281 ctccttggct gggcccagaa agacctgcag agtgaatttg gggttgccac agactcacac
     2341 cacagcagtt ttggttcttc tagctggtct caagacactt ctcagaacta tagcctcggg
     2401 ggcaggagcc ccgttggaga cacaggtctt gggaaaagag actggagcag caagtgtggg
     2461 caagggtccg gggaggggag cactagggag tgggccagca gacacagcct tggccaagag
     2521 gtgattggaa tcggtggcag ccaagacgag agcgaagtgc ctgtccgtga gcgggcagtg
     2581 ggaaggccgg cccagcttgg tgctcagggc ctggaggctg atgcacagca atgggaattc
     2641 gggaagaggg agtcccagga ccctcactcc atccacgaca aagagctcca ggaccaggag
     2701 ttcgggaagc gagattcctt gggttctttc agcacccgag atgcaagcct tcaagactgg
     2761 gagtttggga agagagcgtc tgtgagcacc aaccaggata cagatgagaa tgatcaagaa
     2821 ctggggatga agaacctctc tcgtggctac agcagccagg atgctgaaga gcaggaccgg
     2881 gagtttgaga agcgagattc tgtactggac atccatggca gccgggccac agcccagcag
     2941 aaccaggagt tcgggaagag tgcttggttc caggattaca gtagtggtgg tggcggctca
     3001 agggtgctcg gctcacagga gagaggtttc ggaattcgat ctctgagctc agggttcagc
     3061 cccgaggaag ctcagcagca agatgaggag tttgagaaga agaccccagt tggtgaagac
     3121 aggttttgtg aggccagcag ggatgtgggt cacctggaag aaggagcatc tgggggcctg
     3181 ctgagcccca gcacacctca ttctcgagat ggagctgcca ggccaaaaga cgaaggcagc
     3241 tggcaagatg gtgactccag ccaggagatc acaaggctgc aggggagaat gcaggcagaa
     3301 agtcagagcc ctaccaacgt ggacctggaa gacaaagaga gagagcagag aggctgggcc
     3361 ggggagttca gcctcggtgt tgcagcccag tcggaggcag catttagtcc agggcggcaa
     3421 gactggagca gggacgtgtg tgtggaggcc tctgagagta gctatcagtt tggcatcatc
     3481 ggcaatgaca gagtgagtgg tgctggcctc agcccttcca ggaagagtgg aggtggccac
     3541 tttgtgcctc ccggagagac aaaggccggg gctgtggatt ggactgacca gctaggtctc
     3601 aggaacttgg aggtgtctag ctgtgtgagt tctgaaggcc caagcgaggc tagagagaat
     3661 gttgtaggac agatgggctg gtcagacagc ctgggcttga acaatggaga tctggccagg
     3721 cgtttaggaa ctggagagtc tgaggagccc aggagcctgg gagttgggga aaaggactgg
     3781 acttccagcg tggaggcgag gaacagagat ttgccagggc aggcagaggt aggaaggcac
     3841 agccaggcca gagagagtgg tgtgggggag cccgactggt caggggcaga ggccggagag
     3901 ttccttaagt caagagagcg tggagttgga caggcagatt ggacacctga tcttggattg
     3961 agaaacatgg ccccaggagc aggctgcagc cctggagagc ccagggaact tggggtgggt
     4021 caggtagact ggggtgacga tctaggcctg aggaatttgg aggtgtcctg tgacctagag
     4081 tcgggaggct ctcggggctg tggagttggg caaatggact gggcccaaga cttgggactc
     4141 cggaacctta ggctctgtgg ggccccaagt gaagttaggg aatgtggggt ggggagagtg
     4201 ggccctgacc tagagctaga tcccaagagt agtggtagct tgtcccctgg tttggagact
     4261 gaagacccgt tggaagccag ggagctgggg gttggtgaaa taagtgggcc agagacacag
     4321 ggtgaagaca gctcgtcacc ttcctttgag actccttctg aagacactgg aatggatacg
     4381 ggagaagcac ccagcttggg agccagcccc agcagttgtc tgactcgctc gccaccttct
     4441 ggctcccaga gccttttgga ggggataatg acagccagca gctctaaggg agctcctcag
     4501 agggaatcag cagcttccgg ctcccgggtt ctgttggagg aggaaggact cgctgcaggt
     4561 gccggccaag gggagcccca ggagcctagc agagctcctt tgccatcctc gaggcctcag
     4621 cctgatggcg aagccagcca ggtagaagag gtggatggca cgtggagtct tacgggggcg
     4681 gctaggcaaa atgagcaggc atcagccccg cccccccggc ggcctccccg aggacttctg
     4741 cccagctgcc ccagtgagga cttctctttt atagaggaca ctgagatcct tgatagtgcc
     4801 atgtatcgga gtcgtgccaa cctaggacgt aagcgggggc accgggcccc agccatccgg
     4861 cctgggggta ccctgggact gtcagagaca gcagactcgg atactcggct gttccaagat
     4921 tcaaccgagc caagggcctc ccgggtgcca tcttcagatg aggaggttgt agaggagcct
     4981 cagagccgcc ggacacggat gtccttgggc actaaagggc tgaaagtcaa cctctttcct
     5041 ggcctgagcc catcagcctt gaaggccaag ctacgctccc ggaaccgctc agctgaggag
     5101 ggggaggtga cagagagcaa atcaagccag aaagagtctt ccgtccagcg ttctaagtcc
     5161 tgcaaggtcc cagggctagg gaagcccctt acattacccc caaagccaga aaaatcctca
     5221 gggtcagaag gatcgtcgcc caactggctg caagccctga agctaaaaaa gaaaaagatc
     5281 tgatcagggg ccaaggtcct tcccatctgg cagtctcagg cagtgccatt cctgtggggt
     5341 ccccaagtga ggagacagct ggagccccac cagggctcag actgcagcct cctttcccct
     5401 ccacttctga ggagtgtctg ggaggcacat ttatgcactt tgtatcaccg tcccaacttc
     5461 ttgcacccct tcagccccca actggattcc cgtgcccagt ggtgggaggt cttgtccttc
     5521 cctcagtctc ttccctttac cctctttgct tccatcttct gcctcccttg ggttttcttt
     5581 tgataccaat ttatagcatt tttataaaag cctttgattt ttgtaatggg tgggctccca
     5641 ccccaagccc caccccaggt ctccctctgc cccactaggt gccccacaga gaccaatgac
     5701 attttaccac ttgaaacaat gaataaagtt ttttgggaat tggggttaaa aaaaaaaaaa
     5761 aaaaaaaaaa aaaaaaaaaa a
//
