LOCUS       NM_009404               1230 bp    mRNA    linear   ROD 11-JUN-2024
DEFINITION  Mus musculus tumor necrosis factor (ligand) superfamily, member 9
            (Tnfsf9), mRNA.
ACCESSION   NM_009404
VERSION     NM_009404.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1230)
  AUTHORS   Li,Z., Gao,T., Wang,J., Zhang,X., Zhang,Y., Zhang,L., Yang,P. and
            Liu,J.
  TITLE     Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke
            reperfusion injury with the progression of acute ischaemic stroke
  JOURNAL   J Neurochem 168 (6), 1030-1044 (2024)
   PUBMED   38344886
  REMARK    GeneRIF: Ferroptosis mediated by TNFSF9 interferes in acute
            ischaemic stroke reperfusion injury with the progression of acute
            ischaemic stroke.
REFERENCE   2  (bases 1 to 1230)
  AUTHORS   Qiu,F., Liu,Y., Liu,Y., Zhao,Z., Zhou,L., Chen,P., Du,Y., Wang,Y.,
            Sun,H., Zeng,C., Wang,X., Liu,Y., Pan,H. and Ke,C.
  TITLE     CD137L Inhibition Ameliorates Hippocampal Neuroinflammation and
            Behavioral Deficits in a Mouse Model of Sepsis-Associated
            Encephalopathy
  JOURNAL   Neuromolecular Med 25 (4), 616-631 (2023)
   PUBMED   37796401
  REMARK    GeneRIF: CD137L Inhibition Ameliorates Hippocampal
            Neuroinflammation and Behavioral Deficits in a Mouse Model of
            Sepsis-Associated Encephalopathy.
REFERENCE   3  (bases 1 to 1230)
  AUTHORS   Yang,P., Zang,G., Yan,Y., Zhong,W., Li,B., Xu,Y., Shao,C., Wang,Z.,
            Pu,J. and Yuan,W.
  TITLE     CD137-CD137L Aggravates Calcification of Vascular Smooth Muscle
            Cell and Vasculature of ApoE-/- Mice Via Rab7-Mediated Autophagy
  JOURNAL   J Cardiovasc Transl Res 15 (6), 1297-1314 (2022)
   PUBMED   35763154
  REMARK    GeneRIF: CD137-CD137L Aggravates Calcification of Vascular Smooth
            Muscle Cell and Vasculature of ApoE[-/-] Mice Via Rab7-Mediated
            Autophagy.
REFERENCE   4  (bases 1 to 1230)
  AUTHORS   Bella,A., Arrizabalaga,L., Di Trani,C.A., Cirella,A.,
            Fernandez-Sendin,M., Gomar,C., Russo-Cabrera,J.S., Rodriguez,I.,
            Gonzalez-Gomariz,J., Alvarez,M., Teijeira,A., Medina-Echeverz,J.,
            Hinterberger,M., Hochrein,H., Melero,I., Berraondo,P. and Aranda,F.
  TITLE     Synergistic antitumor response with recombinant modified virus
            Ankara armed with CD40L and CD137L against peritoneal
            carcinomatosis
  JOURNAL   Oncoimmunology 11 (1), 2098657 (2022)
   PUBMED   35859732
  REMARK    GeneRIF: Synergistic antitumor response with recombinant modified
            virus Ankara armed with CD40L and CD137L against peritoneal
            carcinomatosis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1230)
  AUTHORS   McKenzie,D.R., Hart,R., Bah,N., Ushakov,D.S., Munoz-Ruiz,M.,
            Feederle,R. and Hayday,A.C.
  TITLE     Normality sensing licenses local T cells for innate-like tissue
            surveillance
  JOURNAL   Nat Immunol 23 (3), 411-422 (2022)
   PUBMED   35165446
REFERENCE   6  (bases 1 to 1230)
  AUTHORS   Loo,D.T., Chalupny,N.J., Bajorath,J., Shuford,W.W., Mittler,R.S.
            and Aruffo,A.
  TITLE     Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of
            the tumor necrosis factor receptor superfamily, and comparison with
            human 4-1BB
  JOURNAL   J Biol Chem 272 (10), 6448-6456 (1997)
   PUBMED   9045669
REFERENCE   7  (bases 1 to 1230)
  AUTHORS   DeBenedette,M.A., Chu,N.R., Pollok,K.E., Hurtado,J., Wade,W.F.,
            Kwon,B.S. and Watts,T.H.
  TITLE     Role of 4-1BB ligand in costimulation of T lymphocyte growth and
            its upregulation on M12 B lymphomas by cAMP
  JOURNAL   J Exp Med 181 (3), 985-992 (1995)
   PUBMED   7532686
REFERENCE   8  (bases 1 to 1230)
  AUTHORS   Zhou,Z., Kim,S., Hurtado,J., Lee,Z.H., Kim,K.K., Pollok,K.E. and
            Kwon,B.S.
  TITLE     Characterization of human homologue of 4-1BB and its ligand
  JOURNAL   Immunol Lett 45 (1-2), 67-73 (1995)
   PUBMED   7622190
REFERENCE   9  (bases 1 to 1230)
  AUTHORS   Alderson,M.R., Smith,C.A., Tough,T.W., Davis-Smith,T.,
            Armitage,R.J., Falk,B., Roux,E., Baker,E., Sutherland,G.R. and
            Din,W.S.
  TITLE     Molecular and biological characterization of human 4-1BB and its
            ligand
  JOURNAL   Eur J Immunol 24 (9), 2219-2227 (1994)
   PUBMED   8088337
REFERENCE   10 (bases 1 to 1230)
  AUTHORS   Goodwin,R.G., Din,W.S., Davis-Smith,T., Anderson,D.M., Gimpel,S.D.,
            Sato,T.A., Maliszewski,C.R., Brannan,C.I., Copeland,N.G.,
            Jenkins,N.A. et al.
  TITLE     Molecular cloning of a ligand for the inducible T cell gene 4-1BB:
            a member of an emerging family of cytokines with homology to tumor
            necrosis factor
  JOURNAL   Eur J Immunol 23 (10), 2631-2641 (1993)
   PUBMED   8405064
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK155610.1.
            
            On Apr 5, 2007 this sequence version replaced NM_009404.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK155610.1, AK169471.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1230              AK155610.1         2-1231
FEATURES             Location/Qualifiers
     source          1..1230
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 29.67 cM"
     gene            1..1230
                     /gene="Tnfsf9"
                     /gene_synonym="4-1BB-L; 4-1BBL; Cd137l; Ly63l"
                     /note="tumor necrosis factor (ligand) superfamily, member
                     9"
                     /db_xref="GeneID:21950"
                     /db_xref="MGI:MGI:1101058"
     exon            1..476
                     /gene="Tnfsf9"
                     /gene_synonym="4-1BB-L; 4-1BBL; Cd137l; Ly63l"
                     /inference="alignment:Splign:2.1.0"
     exon            477..513
                     /gene="Tnfsf9"
                     /gene_synonym="4-1BB-L; 4-1BBL; Cd137l; Ly63l"
                     /inference="alignment:Splign:2.1.0"
     exon            514..1230
                     /gene="Tnfsf9"
                     /gene_synonym="4-1BB-L; 4-1BBL; Cd137l; Ly63l"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1230
                     /gene="Tnfsf9"
                     /gene_synonym="4-1BB-L; 4-1BBL; Cd137l; Ly63l"
                     /note="putative"
ORIGIN      
        1 ataaagcacg ggcactggcg ggagacgtgc actgaccgac cgtggtaatg gaccagcaca
       61 cacttgatgt ggaggatacc gcggatgcca gacatccagc aggtacttcg tgcccctcgg
      121 atgcggcgct cctcagagat accgggctcc tcgcggacgc tgcgctcctc tcagatactg
      181 tgcgccccac aaatgccgcg ctccccacgg atgctgccta ccctgcggtt aatgttcggg
      241 atcgcgaggc cgcgtggccg cctgcactga acttctgttc ccgccaccca aagctctatg
      301 gcctagtcgc tttggttttg ctgcttctga tcgccgcctg tgttcctatc ttcacccgca
      361 ccgagcctcg gccagcgctc acaatcacca cctcgcccaa cctgggtacc cgagagaata
      421 atgcagacca ggtcacccct gtttcccaca ttggctgccc caacactaca caacagggct
      481 ctcctgtgtt cgccaagcta ctggctaaaa accaagcatc gttgtgcaat acaactctga
      541 actggcacag ccaagatgga gctgggagct catacctatc tcaaggtctg aggtacgaag
      601 aagacaaaaa ggagttggtg gtagacagtc ccgggctcta ctacgtattt ttggaactga
      661 agctcagtcc aacattcaca aacacaggcc acaaggtgca gggctgggtc tctcttgttt
      721 tgcaagcaaa gcctcaggta gatgactttg acaacttggc cctgacagtg gaactgttcc
      781 cttgctccat ggagaacaag ttagtggacc gttcctggag tcaactgttg ctcctgaagg
      841 ctggccaccg cctcagtgtg ggtctgaggg cttatctgca tggagcccag gatgcataca
      901 gagactggga gctgtcttat cccaacacca ccagctttgg actctttctt gtgaaacccg
      961 acaacccatg ggaatgagaa ctatccttct tgtgactcct agttgctaag tcctcaagct
     1021 gctatgtttt atggggtctg agcaggggtc ccttccatga ctttctcttg tctttaactg
     1081 gacttggtat ttattctgag catagctcag acaagacttt atataattca ctagatagca
     1141 ttagtaaact gctgggcagc tgctagataa aaaaaaattt ctaaatcaaa gtttatattt
     1201 atattaatat ataaaaataa atgtgtttgt
//
