LOCUS       NM_009401               3436 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus tumor necrosis factor receptor superfamily, member 8
            (Tnfrsf8), mRNA.
ACCESSION   NM_009401
VERSION     NM_009401.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3436)
  AUTHORS   Cui,D., Zhang,Y., Chen,L., Du,H., Zheng,B., Huang,M., Li,X., Wei,J.
            and Chen,Q.
  TITLE     CD30 plays a role in T-dependent immune response and T cell
            proliferation
  JOURNAL   FASEB J 38 (1), e23365 (2024)
   PUBMED   38069862
  REMARK    GeneRIF: CD30 plays a role in T-dependent immune response and T
            cell proliferation.
REFERENCE   2  (bases 1 to 3436)
  AUTHORS   Foreman,T.W., Nelson,C.E., Sallin,M.A., Kauffman,K.D., Sakai,S.,
            Otaizo-Carrasquero,F., Myers,T.G. and Barber,D.L.
  TITLE     CD30 co-stimulation drives differentiation of protective T cells
            during Mycobacterium tuberculosis infection
  JOURNAL   J Exp Med 220 (8) (2023)
   PUBMED   37097292
  REMARK    GeneRIF: CD30 co-stimulation drives differentiation of protective T
            cells during Mycobacterium tuberculosis infection.
REFERENCE   3  (bases 1 to 3436)
  AUTHORS   Lyu,J., Li,Z., Roberts,J.P., Qi,Y.A. and Xiong,J.
  TITLE     The short-chain fatty acid acetate coordinates with CD30 to
            modulate T-cell survival
  JOURNAL   Mol Biol Cell 34 (8), br11 (2023)
   PUBMED   37163337
REFERENCE   4  (bases 1 to 3436)
  AUTHORS   Fukushima,Y., Sakamoto,K., Matsuda,M., Yoshikai,Y., Yagita,H.,
            Kitamura,D., Chihara,M., Minato,N. and Hattori,M.
  TITLE     cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic
            activation of senescence-associated T cells
  JOURNAL   Cell Rep 40 (12), 111373 (2022)
   PUBMED   36130493
REFERENCE   5  (bases 1 to 3436)
  AUTHORS   Sato,Y., Oguchi,A., Fukushima,Y., Masuda,K., Toriu,N.,
            Taniguchi,K., Yoshikawa,T., Cui,X., Kondo,M., Hosoi,T.,
            Komidori,S., Shimizu,Y., Fujita,H., Jiang,L., Kong,Y.,
            Yamanashi,T., Seita,J., Yamamoto,T., Toyokuni,S., Hamazaki,Y.,
            Hattori,M., Yoshikai,Y., Boor,P., Floege,J., Kawamoto,H.,
            Murakawa,Y., Minato,N. and Yanagita,M.
  TITLE     CD153/CD30 signaling promotes age-dependent tertiary lymphoid
            tissue expansion and kidney injury
  JOURNAL   J Clin Invest 132 (2) (2022)
   PUBMED   34813503
  REMARK    GeneRIF: CD153/CD30 signaling promotes age-dependent tertiary
            lymphoid tissue expansion and kidney injury.
REFERENCE   6  (bases 1 to 3436)
  AUTHORS   Texido,G., Jacobs,H., Meiering,M., Kuhn,R., Roes,J., Muller,W.,
            Gilfillan,S., Fujiwara,H., Kikutani,H., Yoshida,N., Amakawa,R.,
            Benoist,C., Mathis,D., Kishimoto,T., Mak,T.W. and Rajewsky,K.
  TITLE     Somatic hypermutation occurs in B cells of terminal
            deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and
            CD30-deficient mouse mutants
  JOURNAL   Eur J Immunol 26 (8), 1966-1969 (1996)
   PUBMED   8765046
REFERENCE   7  (bases 1 to 3436)
  AUTHORS   Amakawa,R., Hakem,A., Kundig,T.M., Matsuyama,T., Simard,J.J.,
            Timms,E., Wakeham,A., Mittruecker,H.W., Griesser,H., Takimoto,H.,
            Schmits,R., Shahinian,A., Ohashi,P., Penninger,J.M. and Mak,T.W.
  TITLE     Impaired negative selection of T cells in Hodgkin's disease antigen
            CD30-deficient mice
  JOURNAL   Cell 84 (4), 551-562 (1996)
   PUBMED   8598042
REFERENCE   8  (bases 1 to 3436)
  AUTHORS   Bowen,M.A., Lee,R.K., Miragliotta,G., Nam,S.Y. and Podack,E.R.
  TITLE     Structure and expression of murine CD30 and its role in cytokine
            production
  JOURNAL   J Immunol 156 (2), 442-449 (1996)
   PUBMED   8543792
REFERENCE   9  (bases 1 to 3436)
  AUTHORS   McClive,P.J. and Morahan,G.
  TITLE     Assignment of the mouse homologues of 6 loci from HSA1p to
            chromosomes 3 and 4
  JOURNAL   Genomics 23 (1), 243-246 (1994)
   PUBMED   7829080
REFERENCE   10 (bases 1 to 3436)
  AUTHORS   Clayton,L.K., Diener,A.C., Lerner,A., Tse,A.G., Koyasu,S. and
            Reinherz,E.L.
  TITLE     Differential regulation of T-cell receptor processing and surface
            expression affected by CD3 theta, an alternatively spliced product
            of the CD3 zeta/eta gene locus
  JOURNAL   J Biol Chem 267 (36), 26023-26030 (1992)
   PUBMED   1464613
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627099.13.
            
            On Apr 27, 2018 this sequence version replaced NM_009401.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U25416.1, BC130026.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AL627099.13        92783-92925         c
            144-231             AL627099.13        80839-80926         c
            232-348             AL627099.13        76495-76611         c
            349-492             AL627099.13        74611-74754         c
            493-583             AL627099.13        70860-70950         c
            584-750             AL627099.13        70355-70521         c
            751-841             AL627099.13        66187-66277         c
            842-939             AL627099.13        65740-65837         c
            940-1038            AL627099.13        63087-63185         c
            1039-1092           AL627099.13        62907-62960         c
            1093-1118           AL627099.13        55287-55312         c
            1119-1332           AL627099.13        52044-52257         c
            1333-3436           AL627099.13        44893-46996         c
FEATURES             Location/Qualifiers
     source          1..3436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 78.17 cM"
     gene            1..3436
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /note="tumor necrosis factor receptor superfamily, member
                     8"
                     /db_xref="GeneID:21941"
                     /db_xref="MGI:MGI:99908"
     exon            1..143
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1577
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /note="CD30L receptor; lymphocyte activation antigen CD30"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 8 precursor"
                     /protein_id="NP_033427.1"
                     /db_xref="CCDS:CCDS18915.1"
                     /db_xref="GeneID:21941"
                     /db_xref="MGI:MGI:99908"
                     /translation="MSALLTAAGLLFLGMLQAFPTDRPLKTTCAGDLSHYPGEAARNC
                     CYQCPSGLSPTQPCPRGPAHCRKQCAPDYYVNEDGKCTACVTCLPGLVEKAPCSGNSP
                     RICECQPGMHCCTPAVNSCARCKLHCSGEEVVKSPGTAKKDTICELPSSGSGPNCSNP
                     GDRKTLTSHATPQAMPTLESPANDSARSLLPMRVTNLVQEDATELVKVPESSSSKARE
                     PSPDPGNAEKNMTLELPSPGTLPDISTSENSKEPASTASTLSLVVDAWTSSRMQPTSP
                     LSTGTPFLDPGPVLFWVAMVVLLVGSGSFLLCYWKACRRRFQQKFHLDYLVQTFQPKM
                     EQTDSCPTEKLTQPQRSGSVTDPSTGHKLSPVSPPPAVETCASVGATYLENLPLLDDS
                     PAGNPFSPREPPEPRVSTEHTNNRIEKIYIMKADTVIVGSVKTEVPEGRAPAGSTESE
                     LEAELEVDHAPHYPEQETEPPLGSCTEVMFSVEEGGKEDHGPTTVSEK"
     exon            144..231
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            232..348
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            349..492
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            493..583
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            584..750
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            751..841
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            842..939
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1038
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1092
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1118
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1332
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..3436
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3412..3417
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /note="hexamer: AATAAA"
     polyA_site      3432
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30; D1S166E; Ki; Ki-1"
                     /note="major polyA site"
ORIGIN      
        1 agtcacatta gaagtgattt caccgcggga gagtcagggt gccggcaggt ggccaggcgc
       61 tggagactcg ggaagccaag atgagcgccc tactcaccgc agcggggttg ctgttcctgg
      121 ggatgcttca agccttccca acggatcgac cactcaagac cacctgtgcc ggagacctca
      181 gccactaccc aggggaggct gccaggaact gctgttacca gtgcccctca gggttgtctc
      241 cgacacagcc atgcccacgg ggtcctgccc actgcaggaa gcagtgtgca cctgactact
      301 acgtcaatga agacgggaag tgcacagcct gcgtgacctg tttgccaggc cttgtggaga
      361 aggctccgtg ttccgggaac tctcctcgaa tctgtgagtg tcagcctggc atgcactgct
      421 gcacaccagc agtcaattcc tgcgcccgct gcaaactcca ctgttctgga gaggaggttg
      481 tcaagtctcc aggcacagca aagaaggaca ctatctgtga gctgccttcc tcgggatctg
      541 gtcccaattg ctccaatccg ggtgaccgca agacacttac tagccatgcc actcctcagg
      601 ccatgcctac tctagaatcc ccagccaatg acagtgcaag gagcttgctg ccaatgcgtg
      661 tcaccaacct tgtgcaggaa gatgctactg agttggtgaa ggttccagaa tcttcctcgt
      721 ccaaggcaag ggagcccagt ccagatccag gtaatgcaga gaagaatatg accttggagc
      781 ttccatctcc agggacactc cctgacatca gcacctcaga aaacagcaag gagcctgcaa
      841 gtaccgcctc caccctaagc cttgtggtag atgcctggac cagcagcagg atgcagccca
      901 cctctccatt gtccacggga acaccatttc tggatccagg gcccgtgctc ttctgggtgg
      961 ccatggtggt gctactggtt ggctccggct cctttctcct gtgttactgg aaggcctgta
     1021 ggaggcggtt ccagcagaag tttcacctgg actacctagt gcagaccttc cagcccaaga
     1081 tggagcagac agattcctgt cctactgaaa agctaaccca gccacagaga agcgggtcgg
     1141 tgacagatcc cagcacggga cacaagttga gcccagtgag ccctcctcca gctgtagaga
     1201 cttgtgccag tgttggggcc acctacctgg agaacctgcc gctgctggat gacagcccag
     1261 ctgggaatcc tttttctccc agggaacctc cagagccccg ggtatccacg gaacacacca
     1321 ataacaggat tgagaaaatc tacatcatga aggccgacac agtgatcgtg ggctctgtaa
     1381 aaactgaagt ccctgagggc cgggctccag cagggtctac agagtctgag ttggaagctg
     1441 aactagaagt ggaccatgcc ccccattacc cggagcagga gacagaacca cctctgggca
     1501 gctgcactga ggtcatgttc tcggtggagg aaggaggaaa agaggaccat gggcccacga
     1561 ctgtctctga gaagtgacaa ccattgttag ctggggctag agagcagctg agtgtaccct
     1621 tgagatcaag ttagcacctg ggaagctacc acaacttgaa ctgaagaccc agcatccaag
     1681 gtagcccaga atgaagcctt cagctgctgc caagagcact ggcccctggg ccccatcagt
     1741 gggcactcac catcaggctg atgtctactg ggggagaagc cacaggcttg atccaagctt
     1801 ccttgcccac actcctatgc cctgccttct ctccttgggt ctcgagtgat ggctttactg
     1861 ccatgctatt agcctccagc tgtagacatg gctccctgtt acagaaccag cacctattgc
     1921 ttctactctt gagacagagg gaagttaaag aatgaatgct cgtcatcact ggcacaagga
     1981 tggcctgtac ccatcacaca gggagggcag aatgagaccc ttttggcaca gcctccctgt
     2041 tctatggacc tcctcagcag ctgcagtgac cccacctgac aagcactgct caagactatg
     2101 ctttgcccaa ggacttcctg tcacacggag atgggagaac tgtagtcctg gaggttctta
     2161 acactttgtg ccattatctg ttccaccctg gaaacgaaga agcattgtcc caaagcctcc
     2221 aggatcaggt ccaatgacac ctagctccca aaggaaactc tagcaagtgg gagcctatct
     2281 ttgaaggtac cctgctgctc acactgctta gcccacgccc actgtgagga ggccgttctg
     2341 gtgaacatac ctgaagatct gcttttaatg ttttgttttg tcttgttttc cttttgaggt
     2401 actgagcttg aacccctggc tttgtgcatg ccaggcaaat gttgcagggc tgatcccacc
     2461 caccccagac cagcatttca tactaagcac taaagctgct gtcactcaca gcctggctca
     2521 cccactggca gctgcatact cttgtatcaa gcagccaact ggatgacaca tctgctctgt
     2581 ggcagcttgg agactctgga cttacccttg ggccaggcag ggagaattct gtttactcac
     2641 tagctgtttg ctgtctggag gaagttggga ccctgtcaag aatcacgagg ggagtttctg
     2701 aaaccgcctg aatatttggg gaaaaactgg agcagctgag tgccatcaga ggcgttatac
     2761 cacagtctgg atccaggcca gaagggatgt gtgggggatg aagagttgcc catttgtctt
     2821 gtgcaaggac acggtggata tgtgggcata cacagtggcc ccaaagccat gtcatgatga
     2881 ccacatggat accacacttt tggaagatat tgcccaactt tttctttttc taagatgaga
     2941 tcttgttctg tatcctaggt tagattcaaa catgatatgt agctcatgct gaccctgaac
     3001 ctgtaacctt cccatcttaa cttcctgagg gatgacaggc ttgagccact atgccagact
     3061 gccacacatt tcagcaaagt gacatattcc cttacagagt ggctcttcac acaatttttg
     3121 accctctaag aatccttaag ggcctgttaa aacaatggat ttgtaaggct gaaggcttat
     3181 cacagagttg agtagtgaga ggtcctgaac acgaagggtg ccaggggtct ggtctgccgc
     3241 cccaccccca cccccacgcc atttccccca ggcagggctt ttctctgtgt gcacgatact
     3301 cacagccaag ggcaggagcc tttgaccagc tgtgtgccct ttaaatttct ccctgtccac
     3361 ccgggcagtc tctttttccc tgtttatgtc ctgtcctcca aggatgctgg gaataaaggg
     3421 tctctgctca cacggc
//
