LOCUS       NM_011610               4913 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus tumor necrosis factor receptor superfamily, member 1b
            (Tnfrsf1b), mRNA.
ACCESSION   NM_011610
VERSION     NM_011610.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4913)
  AUTHORS   Desu,H.L., Thougaard,E., Carney,B.N., Illiano,P., Plastini,M.J.,
            Florimon,Y., Mini,A., Guastucci,C., Kang,B., Lee,J.K.,
            Lambertsen,K.L. and Brambilla,R.
  TITLE     TNFR2 signaling in oligodendrocyte precursor cells suppresses their
            immune-inflammatory function and detrimental microglia activation
            in CNS demyelinating disease
  JOURNAL   Brain Behav Immun 123, 81-98 (2025)
   PUBMED   39243989
REFERENCE   2  (bases 1 to 4913)
  AUTHORS   Boutou,A., Roufagalas,I., Politopoulou,K., Tastsoglou,S.,
            Abouzeid,M., Skoufos,G., Verdu de Juan,L., Ko,J.H., Kyrargyri,V.,
            Hatzigeorgiou,A.G., Barnum,C.J., Tesi,R.J., Bauer,J., Lassmann,H.,
            Johnson,M.R. and Probert,L.
  TITLE     Microglia regulate cortical remyelination via TNFR1-dependent
            phenotypic polarization
  JOURNAL   Cell Rep 43 (11), 114894 (2024)
   PUBMED   39446583
REFERENCE   3  (bases 1 to 4913)
  AUTHORS   Alam,M.S., Gaida,M.M., Witzel,H.R., Otsuka,S., Abbasi,A.,
            Guerin,T., Abdelmaksoud,A., Wong,N., Cam,M.C., Kozlov,S. and
            Ashwell,J.D.
  TITLE     TNFR1 signaling promotes pancreatic tumor growth by limiting
            dendritic cell number and function
  JOURNAL   Cell Rep Med 5 (9), 101696 (2024)
   PUBMED   39178856
REFERENCE   4  (bases 1 to 4913)
  AUTHORS   Van Roy,Z. and Kielian,T.
  TITLE     Tumor necrosis factor regulates leukocyte recruitment but not
            bacterial persistence during Staphylococcus aureus craniotomy
            infection
  JOURNAL   J Neuroinflammation 21 (1), 179 (2024)
   PUBMED   39044282
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4913)
  AUTHORS   Srivastava,N., Hu,H., Peterson,O.J., Vomund,A.N., Stremska,M.,
            Zaman,M., Giri,S., Li,T., Lichti,C.F., Zakharov,P.N., Zhang,B.,
            Abumrad,N.A., Chen,Y.G., Ravichandran,K.S., Unanue,E.R. and Wan,X.
  TITLE     CXCL16-dependent scavenging of oxidized lipids by islet macrophages
            promotes differentiation of pathogenic CD8+ T cells in diabetic
            autoimmunity
  JOURNAL   Immunity 57 (7), 1629-1647 (2024)
   PUBMED   38754432
REFERENCE   6  (bases 1 to 4913)
  AUTHORS   Brownell,E., Ranges,G.E., Sarr,T., Fiorentino,L., Godfrey,M.,
            Pekar,S., Hart,J., Kamarck,M., Rae,P.M., Ruddle,F.H. et al.
  TITLE     Chromosome assignments of the human TNF p55 and p75 receptor genes
  JOURNAL   J Exp Zool 262 (3), 340-342 (1992)
   PUBMED   1322446
REFERENCE   7  (bases 1 to 4913)
  AUTHORS   Milatovich,A., Song,K., Heller,R.A. and Francke,U.
  TITLE     Tumor necrosis factor receptor genes, TNFR1 and TNFR2, on human
            chromosomes 12 and 1
  JOURNAL   Somat Cell Mol Genet 17 (5), 519-523 (1991)
   PUBMED   1662415
REFERENCE   8  (bases 1 to 4913)
  AUTHORS   Goodwin,R.G., Anderson,D., Jerzy,R., Davis,T., Brannan,C.I.,
            Copeland,N.G., Jenkins,N.A. and Smith,C.A.
  TITLE     Molecular cloning and expression of the type 1 and type 2 murine
            receptors for tumor necrosis factor
  JOURNAL   Mol Cell Biol 11 (6), 3020-3026 (1991)
   PUBMED   1645445
REFERENCE   9  (bases 1 to 4913)
  AUTHORS   Lewis,M., Tartaglia,L.A., Lee,A., Bennett,G.L., Rice,G.C.,
            Wong,G.H., Chen,E.Y. and Goeddel,D.V.
  TITLE     Cloning and expression of cDNAs for two distinct murine tumor
            necrosis factor receptors demonstrate one receptor is species
            specific
  JOURNAL   Proc Natl Acad Sci U S A 88 (7), 2830-2834 (1991)
   PUBMED   1849278
REFERENCE   10 (bases 1 to 4913)
  AUTHORS   Rothe,J.G., Brockhaus,M., Gentz,R. and Lesslauer,W.
  TITLE     Molecular cloning and expression of the mouse Tnf receptor type b
  JOURNAL   Immunogenetics 34 (5), 338-340 (1991)
   PUBMED   1657766
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK140332.1 and BY489212.1.
            
            On Sep 26, 2005 this sequence version replaced NM_011610.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140332.1, AK004844.2 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4896              AK140332.1         2-4897
            4897-4913           BY489212.1         342-358
FEATURES             Location/Qualifiers
     source          1..4913
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 78.17 cM"
     gene            1..4913
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="tumor necrosis factor receptor superfamily, member
                     1b"
                     /db_xref="GeneID:21938"
                     /db_xref="MGI:MGI:1314883"
     exon            1..147
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1494
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="TNF-RII; TNFR-II; p80 TNF-alpha receptor; tumor
                     necrosis factor receptor 2; tumor necrosis factor receptor
                     type II; p75 TNFR; TNF receptor beta chain"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 1B precursor"
                     /protein_id="NP_035740.2"
                     /db_xref="CCDS:CCDS18914.1"
                     /db_xref="GeneID:21938"
                     /db_xref="MGI:MGI:1314883"
                     /translation="MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQ
                     EYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCT
                     TDQVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGN
                     VLCKACAPGTFSDTTSSTDVCRPHRICSILAIPGNASTDAVCAPESPTLSAIPRTLYV
                     SQPEPTRSQPLDQEPGPSQTPSILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLM
                     LGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLES
                     SASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSS
                     SDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQSHEKPLP
                     LGVPDMGMKPSQAGWFDQIAVKVA"
     exon            148..250
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            251..379
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            380..532
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            533..626
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            627..859
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            860..937
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            938..972
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1180
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..4913
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2855..2860
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="hexamer: TATAAA"
     polyA_site      2882
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="major polyA site"
     polyA_site      3024
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="major polyA site"
     regulatory      3776..3781
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="hexamer: AATAAA"
     regulatory      3790..3795
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="hexamer: AATAAA"
     polyA_site      3795
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
     polyA_site      3818
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="major polyA site"
     regulatory      4873..4878
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="hexamer: AATAAA"
     polyA_site      4886
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
     regulatory      4894..4899
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
                     /note="hexamer: ATTAAA"
     polyA_site      4903
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
     polyA_site      4913
                     /gene="Tnfrsf1b"
                     /gene_synonym="CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2;
                     TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80;
                     TNFRII"
ORIGIN      
        1 agtcaccagc tagagcgcag ctgaggcact agagctccag gcacaagggc gggagccacc
       61 gctgccccta tggcgcccgc cgccctctgg gtcgcgctgg tcttcgaact gcagctgtgg
      121 gccaccgggc acacagtgcc cgcccaggtt gtcttgacac cctacaaacc ggaacctggg
      181 tacgagtgcc agatctcaca ggaatactat gacaggaagg ctcagatgtg ctgtgctaag
      241 tgtcctcctg gccaatatgt gaaacatttc tgcaacaaga cctcggacac cgtgtgtgcg
      301 gactgtgagg caagcatgta tacccaggtc tggaaccagt ttcgtacatg tttgagctgc
      361 agttcttcct gtaccactga ccaggtggag atccgcgcct gcactaaaca gcagaaccga
      421 gtgtgtgctt gcgaagctgg caggtactgc gccttgaaaa cccattctgg cagctgtcga
      481 cagtgcatga ggctgagcaa gtgcggccct ggcttcggag tggccagttc aagagcccca
      541 aatggaaatg tgctatgcaa ggcctgtgcc ccagggacgt tctctgacac cacatcatcc
      601 actgatgtgt gcaggcccca ccgcatctgt agcatcctgg ctattcccgg aaatgcaagc
      661 acagatgcag tctgtgcgcc cgagtcccca actctaagtg ccatcccaag gacactctac
      721 gtatctcagc cagagcccac aagatcccaa cccctggatc aagagccagg gcccagccaa
      781 actccaagca tccttacatc gttgggttca acccccatta ttgaacaaag taccaagggt
      841 ggcatctctc ttccaattgg tctgattgtt ggagtgacat cactgggtct gctgatgtta
      901 ggactggtga actgcatcat cctggtgcag aggaaaaaga agccctcctg cctacaaaga
      961 gatgccaagg tgcctcatgt gcctgatgag aaatcccagg atgcagtagg ccttgagcag
     1021 cagcacctgt tgaccacagc acccagttcc agcagcagct ccctagagag ctcagccagc
     1081 gctggggacc gaagggcgcc ccctgggggc catccccaag caagagtcat ggcggaggcc
     1141 caagggtttc aggaggcccg tgccagctcc aggatttcag attcttccca cggaagccac
     1201 gggacccacg tcaacgtcac ctgcatcgtg aacgtctgta gcagctctga ccacagttct
     1261 cagtgctctt cccaagccag cgccacagtg ggagacccag atgccaagcc ctcagcgtcc
     1321 ccaaaggatg agcaggtccc cttctctcag gaggagtgtc cgtctcagtc cccgtgtgag
     1381 actacagaga cactgcagag ccatgagaag cccttgcccc ttggtgtgcc ggatatgggc
     1441 atgaagccca gccaagctgg ctggtttgat cagattgcag tcaaagtggc ctgacccctg
     1501 acaggggtaa caccctgcaa agggaccccc gagaccctga acccatggaa cttcatgact
     1561 tttgctggat ccatttccct tagtggcttc cagagcccca gttgcaggtc aagtgagggc
     1621 tgagacagct agagtggtca aaaactgcca tggtgtttta tgggggcagt cccaggaagt
     1681 tgttgctctt ccatgacccc tctggatctc ctgggctctt gcctgattct tgcttctgag
     1741 aggccccagt attttttcct tctaaggagc taacatcctc ttccatgaat agcacagctc
     1801 ttcagcctga atgctgacac tgcagggcgg ttccagcaag taggagcaag tggtggcctg
     1861 gtagggcaca gaggcccttc aggttagtgc taaactctta ggaagtaccc tctccaagcc
     1921 caccgaaatt cttttgatgc aagaatcaga ggccccatca ggcagagttg ctctgttata
     1981 ggatggtagg gctgtaactc agtggtccag tgtgctttta gcatgccctg ggtttgatcc
     2041 tcagcaacac atgcaaaacg taagtagaca gcagacagca gacagcacag ccagccccct
     2101 gtgtggtttg cagcctctgc ctttgacttt tactctggtg ggcacacaga gggctggagc
     2161 tcctcctcct gaccttctaa tgagcccttc caaggccacg ccttccttca gggaatctca
     2221 gggactgtag agttcccagg cccctgcagc cacctgtctc ttcctacctc agcctggagc
     2281 actccctcta actccccaac ggcttggtac tgtacttgct gtgaccccaa gtgcatgtcc
     2341 gggttaggca ctgtgagttg gaacagctga tgacatcggt tgaaaggccc acccggaaac
     2401 agctgaagcc agctcttttg ccaaaggatt catgccggtt ttctaatcaa cctgctcccc
     2461 tagcatgcct ggaaggaaag ggttcaggag actcctcaag aagcaagttc agtctcaggt
     2521 gcttggatgc catgctcacc gattccactg gatatgaact tggcagagga gcctagttgt
     2581 tgccatggag acttaaagag ctcagcactc tggaatcaag atactggaca cttggggccg
     2641 acttgttaag gctctgcagc atcagactgt agaggggaag gaacacgtct gccccctggt
     2701 ggcccgtcct gggatgacct cgggcctcct aggcaacaaa agaatgaatt ggaaaggact
     2761 gttcctgggt gtggcctcag ctcctgtgct tgtgtggatc cctaaagggt gtgctaagga
     2821 gcaattgcac tgtgtgctgg acagaattcc tgcttataaa tgctttttgt tgttgttttg
     2881 tacactgagc cctggctgag ccaccccacc ccacctccca tcccaccttt acagccactc
     2941 ttgcagagaa cctggctgtc tcccacttgt agcctgtgga tgctgaggaa acacccagcc
     3001 aagtagactc caggcttgcc cctatctcct gctctgagtc tggcctcctc attgtgttgt
     3061 gggaaggaga cgggttctgt catctcggaa gcccacaccg tggatgtgaa caatggctgt
     3121 actagcttag accagcttag ggctctgcaa tcagaggagg gggagcaggg aacaatttga
     3181 gtgctgacct ataacacatt cctaaaggat gggcagtcca gaatctccct ccttcagtgt
     3241 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtcc atgtttgcat gtatgtgtgt
     3301 gccagtgtgt ggaggccaga ggttggcttt gggtgtgttt gatcactctc agttactgag
     3361 gcagggctct catctgtacc cagagcttgc acattttcta gtctaacttg cttcagggat
     3421 ctctgtctgc ctatggagtg ctcaggttac aggcaggctg ccatacctgc ccgacattta
     3481 catgaatact agagatctga attctggtcc tcacacttgt atacctgcat tttatccact
     3541 aagacatctc tccaagggct cccccttcct atttaataag ttagttttga actggcaaga
     3601 tggctcagtg ggtaaggcag tttgcggaca aacctgatga cctgagttgg atccctgacc
     3661 ataaggtaga agagacctga ttcctgcaag ttgtcctctg accaccaccc catacatgct
     3721 tctgcatatg tgcacacatc acattcttgc acacacactc acataccata aatgtaataa
     3781 atttttttaa ataaattgat tttatctttt aatcattatt tttgcttatc tgtttgttca
     3841 tacatggagt tttgctgtat acccagtctg gctgcatcct ccaggcacct tgaacttgga
     3901 tattctcctg cctcagtttc gagagtgctg agttataggc atgtgcaacc gtgtcaggac
     3961 ccttggcgtt acattatgtt ttcgaatctt atttttccat ctaagactga caaccacctt
     4021 gccaaaggat gaccttgact tttgtatcct cttgcctcta cttcccaagt attgggatga
     4081 caagtctgtc catcctatga tttgtgtggt gctggggctt gaacccaggg gcctcgtgaa
     4141 tgctaggcaa acgcaatcag ctgcccaacc ccgaacttca cttttcacct gtgatttctt
     4201 aacatggttc ctgagcagac agcatgatcc tgttgccttg aggagctctg ctcgttgctt
     4261 tgacaatgct ctatttacta aagaatactt atagagttca agactccaaa gcagcagttc
     4321 ccaacctgtg ggtatgacct cttgggtatc ccatatcaga tatttacatt aaacttataa
     4381 cagaagcaaa attacagtta tggggtagca acaaaataat ttttttttga ggcagggttt
     4441 atctgtgtag ctcactttgt acagactagg ctggccttga acttaaagat ctgcctgcct
     4501 ctgccttctg aatgctggga ttaaatgtgt gtgccaacat gcccagtgca gtgaaataat
     4561 tttattgttg ggtcaccaaa acatgagaaa gagtattaaa aggtcatagc gttaggaagg
     4621 ttgagaacca ctgccccaaa agatagtaga aataggtaat agcattttaa aaaaagatta
     4681 atttcttttt ccgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     4741 gtgtgtgaag ggtgctgaat tccctaaatc tgggattaca gacaattgtg ccaaatgggt
     4801 attgggaacc aaagttgggt tttctgaaag agcagcaagt gcccttaact gctgagccct
     4861 ctctctagct ataataaact tttttttaaa aaaattaaaa aaatttagca ctc
//
