LOCUS       NM_025868               2287 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus thioredoxin-related transmembrane protein 2 (Tmx2),
            transcript variant 1, mRNA.
ACCESSION   NM_025868 XM_006500054
VERSION     NM_025868.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2287)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 2287)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK075750.1, BQ840236.1, AK009759.1 and BY386749.1.
            
            On or before Mar 19, 2014 this sequence version replaced
            XM_006500054.1, NM_025868.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK075750.1, SRR5189685.146111.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-246               AK075750.1         3-248
            247-313             BQ840236.1         109-175
            314-2279            AK009759.1         2-1967
            2280-2287           BY386749.1         426-433
FEATURES             Location/Qualifiers
     source          1..2287
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.45 cM"
     gene            1..2287
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /note="thioredoxin-related transmembrane protein 2"
                     /db_xref="GeneID:66958"
                     /db_xref="MGI:MGI:1914208"
     exon            1..186
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            187..510
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            511..571
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            572..685
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            686..762
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            763..869
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            870..935
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1065
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..2287
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2261..2266
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /note="hexamer: AATAAA"
     polyA_site      2282
                     /gene="Tmx2"
                     /gene_synonym="2310042M24Rik; Txndc14"
                     /note="major polyA site"
ORIGIN      
        1 accccagaaa atcaagttat cccttagggt tgtgaatcgc caaagggctt ctgacactgt
       61 tgcccactgg ccccgcgtag ccctgttatc tcacacctag cgggacaggc tagccacacc
      121 ctcacctgaa ctacaatctg agtggctact cttggcctac tactcacctg gcaattcccg
      181 catcagcatc caataagaga tctacatccg ggtctggagg cgttgcatct gatatttggt
      241 ccaatagaag ccttgctggt gggggcggag gacgaagatt tggggagcgg gagtgagcct
      301 gcgagagagt aggcaggaaa gatggctgtc cttgcgcctc tgattgcttt ggtgtactcg
      361 gtgccgcggc tttctcgatg gctggcccga ccttattgcc ttctgtctgc tctgctttcc
      421 attgctttcc tcctcgtgag gaaactgcca ccgatttgca atggtctccc cacgcaacgc
      481 gaagatggca acccgtgtga ctttgactgg agagaagtgg agatcctgat gttcctcagt
      541 gccattgtga tgatgaagaa ccgcagatcc atcactgtgg agcaacatgt aggcaacatc
      601 tttatgttta gtaaagtggc caacgccatc cttttcttcc gactggatat tcgaatgggt
      661 ctgctatacc tcacactctg catagtgttc ctgatgacct gcaagccccc gctgtacatg
      721 ggtcctgagt atatcaagta cttcaatgat aaaaccattg atgaggagct ggagcgagac
      781 aagagggtca cttggattgt ggagttcttt gccaactggt ctaatgattg ccaatccttt
      841 gctcccatct atgcggactt gtccctcaag tacaactgtt cagggctaaa ttttgggaag
      901 gtagatgttg gacgctacac tgacgttagc acacggtaca aagtgagcac atcacccctc
      961 accagacagc tccctaccct gattctgttc caaggcggca aggaggtcat tcgtcggccg
     1021 cagattgaca agaaaggacg agctgtctct tggacctttt ctgaggagaa tgtgattcga
     1081 gaattcaact tgaatgagct ataccaacga gccaagaagc actcaaaggg tggagacatg
     1141 tcagaagaga agcctgtgga ccctgctccc actactgtgc cagatgggga aaacaagaag
     1201 gacaaatagg atcctgcatt gtttttgctt cctctcctgt caatttcagg aacctttgag
     1261 gcccagttcc agctataacc acaatccttg cctgaggcct tttgatttct gtttggctgt
     1321 gcctgggtag gggcactgtg cctgcttctg attttgaaag aagcatcctg gaaaccatga
     1381 agtattctac tatgaagggc gcatctgccc tggtcagctg tttctcgaag ggagtgatct
     1441 tatcgataga ggtagaaatg gtttccctcc aaggttgggt caatgtgtaa attgctattc
     1501 aacacttgga tattaccagt ctgtggttta attattcctc ctagtgagct tgcaaagcat
     1561 agactaaatt aaaccctaat gttagatgtc agtataaagc ccttagaatt tttcctcaag
     1621 gaccccttct tcctttaggc ctttctgtct tgatctgtgc attaagaaat ttaagtttgg
     1681 ggctggagaa atggcccatc gattaagaaa gagcactggt ggctgctttt ccagagatcc
     1741 tgagttcaat tcccagcaac cacatgatgg ttcataatgg gatctgatgc cctcttctgg
     1801 catgcaggca gaatactata tatagtaagt aaatcgtaaa gagaaaggaa tttaaggggt
     1861 tggagagatg actcagtggc taagagaatt ggctgttctt ccagaggacc caggtttgat
     1921 tcctagcagc acatagaggc taaaccacct gtaactctag tctcaggggc tccaacatcc
     1981 gcccttgacc ttggctggca ctgtatgcat gtagtgcaca aacacgtgac ggaggaacac
     2041 ataaaaggct tgtatgtgtt atcatttaag gtcactgttc ccaattaaaa gccttcaacc
     2101 atgattttca tcattggaaa tagaattgaa tggccaccct gtgttgtggg aactgagaag
     2161 ggcaatataa acctgagagg ttcctttgtg tggtggggcc tgaagaagaa agccccacgg
     2221 ctggacagct gttctctcct cctatcccac cgcttcccct aataaaggga ctgttctttt
     2281 gattgcc
//
