LOCUS       NM_027853               1227 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus thiol methyltransferase 1B (Tmt1b), mRNA.
ACCESSION   NM_027853
VERSION     NM_027853.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1227)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1227)
  AUTHORS   Huang,D. and Yan,H.
  TITLE     Methyltransferase like 7B is upregulated in sepsis and modulates
            lipopolysaccharide-induced inflammatory response and macrophage
            polarization
  JOURNAL   Bioengineered 13 (5), 11753-11766 (2022)
   PUBMED   35603523
  REMARK    GeneRIF: Methyltransferase like 7B is upregulated in sepsis and
            modulates lipopolysaccharide-induced inflammatory response and
            macrophage polarization.
REFERENCE   3  (bases 1 to 1227)
  AUTHORS   Franjic,D., Skarica,M., Ma,S., Arellano,J.I., Tebbenkamp,A.T.N.,
            Choi,J., Xu,C., Li,Q., Morozov,Y.M., Andrijevic,D., Vrselja,Z.,
            Spajic,A., Santpere,G., Li,M., Zhang,S., Liu,Y., Spurrier,J.,
            Zhang,L., Gudelj,I., Rapan,L., Takahashi,H., Huttner,A., Fan,R.,
            Strittmatter,S.M., Sousa,A.M.M., Rakic,P. and Sestan,N.
  TITLE     Transcriptomic taxonomy and neurogenic trajectories of adult human,
            macaque, and pig hippocampal and entorhinal cells
  JOURNAL   Neuron 110 (3), 452-469 (2022)
   PUBMED   34798047
REFERENCE   4  (bases 1 to 1227)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   5  (bases 1 to 1227)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 1227)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK002239.1.
            
            On Apr 6, 2007 this sequence version replaced NM_027853.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002239.1, BC024898.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1227              AK002239.1         2-1228
FEATURES             Location/Qualifiers
     source          1..1227
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 77.2 cM"
     gene            1..1227
                     /gene="Tmt1b"
                     /gene_synonym="0610006F02Rik; Mettl7b"
                     /note="thiol methyltransferase 1B"
                     /db_xref="GeneID:71664"
                     /db_xref="MGI:MGI:1918914"
     exon            1..548
                     /gene="Tmt1b"
                     /gene_synonym="0610006F02Rik; Mettl7b"
                     /inference="alignment:Splign:2.1.0"
     exon            549..1227
                     /gene="Tmt1b"
                     /gene_synonym="0610006F02Rik; Mettl7b"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1227
                     /gene="Tmt1b"
                     /gene_synonym="0610006F02Rik; Mettl7b"
                     /note="putative"
ORIGIN      
        1 agaggcaaaa ctctagtgtt ccacgagacg ctccaccagg agctggtatc atggatgccc
       61 tggttctatt tctgcagctg ctggtgctgc tcctgactct acctctacac ctactggctc
      121 tgctgggctg ctggcagcct atatgcaaaa cctacttccc ttacttcatg gccatgctaa
      181 cagccaggtc ctacaaaaag atggaaagca agaaacggga actatttagc cagataaaag
      241 atctcaaggg gacttccggc aacgtggccc tgctggagct gggctgcggc accggtgcca
      301 acttccagtt ctacccacag ggctgcaagg tcacctgtgt ggacccaaac cccaacttcg
      361 agaagttcct gacaaagagc atggctgaga acaggcacct ccaatatgag cgcttcattg
      421 tggcttacgg agagaacatg aaacaactgg ctgacagctc catggatgtg gtggtctgta
      481 ccctggtgct atgttctgtg cagagcccca gaaaggtcct gcaggaagtc cagagagtcc
      541 tgaggccggg aggcctactg ttcttctggg agcacgtggc tgagcctcag ggaagccggg
      601 ccttcctgtg gcagcgagtt ttagagccta cctggaaaca catcggagat ggttgccacc
      661 tcaccagaga gacctggaaa gacattgaga gggcacagtt ctccgaagtc cagctggaat
      721 ggcagccccc tcccttcagg tggttacctg ttgggcccca catcatggga aaagctgtga
      781 aataaactct ccccaaggat gccatctgat ctccccatct gcagccagaa gtcaccccaa
      841 tacagtactt ctaaggaggg gtcaggtaaa gcatgagaga gactctcagc gccgccgctg
      901 ccgctgccag ggtgatcatt catcagtttc ggccactaga gacagaaaac tacactgcta
      961 agccctggac tttgcccaac ccctttctag gaccgttttc tccctctctc ttgtccctat
     1021 ggtaaagttc tccctggcgt ccttctgaaa ctacaccatg tggccccttg gaactaatcc
     1081 caagtcaatg cgtgtatccc ctgccaggct gcctcagcct ccctccccat tacccactct
     1141 gtccccgggg ttcggaggaa tgggcgagca gaaaaacctt aggatgagag agcggcactc
     1201 aataaagcag ccagagattt tattgtc
//
