LOCUS       NM_172455               2585 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus transmembrane serine protease 7 (Tmprss7), mRNA.
ACCESSION   NM_172455 NM_001162879 XM_622668
VERSION     NM_172455.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2585)
  AUTHORS   Szabo,R., Hobson,J.P., Christoph,K., Kosa,P., List,K. and
            Bugge,T.H.
  TITLE     Regulation of cell surface protease matriptase by HAI2 is essential
            for placental development, neural tube closure and embryonic
            survival in mice
  JOURNAL   Development 136 (15), 2653-2663 (2009)
   PUBMED   19592578
REFERENCE   2  (bases 1 to 2585)
  AUTHORS   Szabo,R., Netzel-Arnett,S., Hobson,J.P., Antalis,T.M. and
            Bugge,T.H.
  TITLE     Matriptase-3 is a novel phylogenetically preserved
            membrane-anchored serine protease with broad serpin reactivity
  JOURNAL   Biochem J 390 (Pt 1), 231-242 (2005)
   PUBMED   15853774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DQ061860.1, AC166572.1 and AK045663.1.
            
            On or before Aug 18, 2010 this sequence version replaced
            NM_001162879.1, NM_172455.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ061860.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               DQ061860.1         2-154
            154-154             AC166572.1         112776-112776
            155-315             DQ061860.1         156-316
            316-316             AC166572.1         117254-117254
            317-444             DQ061860.1         318-445
            445-445             AC166572.1         119055-119055
            446-573             DQ061860.1         447-574
            574-598             AC166572.1         120152-120176
            599-697             DQ061860.1         600-698
            698-698             AC166572.1         122897-122897
            699-1409            AK045663.1         449-1159
            1410-1410           AC166572.1         135981-135981
            1411-2585           AK045663.1         1161-2335
FEATURES             Location/Qualifiers
     source          1..2585
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL x Black Swiss"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 29.84 cM"
     gene            1..2585
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /note="transmembrane serine protease 7"
                     /db_xref="GeneID:208171"
                     /db_xref="MGI:MGI:2686594"
     exon            1..52
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..2494
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /note="transmembrane protease, serine 7; matriptase-3"
                     /codon_start=1
                     /product="transmembrane protease serine 7"
                     /protein_id="NP_766043.3"
                     /db_xref="CCDS:CCDS37347.2"
                     /db_xref="GeneID:208171"
                     /db_xref="MGI:MGI:2686594"
                     /translation="MDKEKSDPSCKSSDLKISNISIQVVSVPGKLPGRRPPRKPIGKP
                     RPRKQPKKRAPFWNVQNKIILFTVFLFILAVTAWTLLWLYISKTESKDAFYFVGMFRI
                     TNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVADVSSNNKGGLL
                     VHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNAG
                     LRSDYSSAVGSDNGCSRYLYADHLTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIE
                     SIQLEADNCITDSLTVYDSLLPIRSAILYRICEPTRTLMSFVSTNNLMLVILKSPYVR
                     RLAGIRAYFEVIPEQKCESTILVKEINSFEGKISSPYYPSYYPPKCKCTWTFQTSLST
                     LGIALKFYNYSITKKSAKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSS
                     RLSDKPLLVEYGGYNISQPCPAGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVTVK
                     PACNSSSFRQHGPLVCDGFRDCEDGQDEQNCTRSIPCTSRTFKCGNDICFRKQNAQCD
                     GIVDCPDGSDEEGCGCSRSSSFLHRIVGGSDSQEGTWPWQVSLHFVGSAYCGASVISR
                     EWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFISPVRRIVVHEYYNSQTFDYDIA
                     LLQLSIAWPETLKQLIQPICIPPAGQKVRSGEKCWVTGWGRRHEADSKGSPVLQQAEV
                     ELIDQTVCVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSW
                     GHGCGRPNFPGVYTRVSSFVPWIHKYVPSLL"
     exon            53..260
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            261..391
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            392..459
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            460..653
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            654..692
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            693..921
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1052
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1165
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1272
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1409
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1517
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1628
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1745
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1917
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2186
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2323
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
     exon            2324..2585
                     /gene="Tmprss7"
                     /gene_synonym="B230219I23Rik; Gm1748"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaaatggat aaagaaaaaa gtgatccttc ctgcaagtcc tcagacctca aaatatccaa
       61 catctccatc caggtggtca gtgtcccagg gaagctacca gggagaagac cacctcgaaa
      121 acccattggc aaacccaggc cccgcaagca gcctaagaag agagctccct tttggaatgt
      181 tcaaaataag attattctct tcacagtgtt tttattcatt ctggcagtca cagcctggac
      241 acttctatgg ctctacatca gtaagacaga gagcaaagat gctttttatt ttgttggaat
      301 gttccgcatc accaacattg agttccttcc tgagtaccgg cagaaggagt ctagggaatt
      361 tctctccatg gcaaagacag tacagcaagt ggtaaacctt gtttatacaa catctgcttt
      421 ctccaaattt tataagcagt ctgtggttgc agacgtcagc agtaacaaca aaggcggtct
      481 cctggtccac ttttggattg tgtttgttat gccacatgcc aagggccaca tcttctgtga
      541 ggagtgtgtg gcggccatct tgaaggactc cattcaaacc agtatcataa accgcacttc
      601 tgtggggagc ttgcagggtc tggctgtgga tatggactct gtggtattaa atgctgggct
      661 ccggtcagat tactcttcag ctgtaggatc tgacaacggc tgctcccggt acttgtatgc
      721 agaccatctg accctccgct accctctgga gatttccgca acctcgggac aactaatgtg
      781 tcacttcaag ttggtggcca tcgtgggtta tctgattcgt ctctccattg aatccatcca
      841 attggaagcc gacaactgta tcaccgactc cctgactgtt tatgactccc tcttgccaat
      901 ccggagtgcc attctataca gaatctgtga acccacaaga acactaatgt ccttcgtttc
      961 tacaaataat ctcatgttgg tgatactgaa gtctccttat gtgcgaaggc tggcagggat
     1021 ccgagcatat tttgaagtca ttccagaaca aaaatgtgaa agcacaatac tggtcaagga
     1081 aatcaacagc tttgagggga aaatctcaag tccgtattac ccaagttact atcctccgaa
     1141 atgcaagtgc acctggacat tccagacttc cctatcaact ctcggcatag ccctgaaatt
     1201 ctacaactat tccataacta agaagagtgc aaaaggctgt gagcacggct ggtgggagat
     1261 taatgaacac atgtactgcg gctcctacat ggatcatgag accattttcc gggtgcccag
     1321 ccccctggtc cacatccagc tccaatgcag ttccaggctt tcagacaagc cactcttggt
     1381 agaatatggc ggttacaaca tcagtcaacc gtgtcctgca ggatctttta ggtgctcctc
     1441 cggtttgtgt gtccctcagg cccagcgttg tgacggagtg aatgactgtt tcgacgaaag
     1501 tgatgaactt ttctgtgtga ctgtaaaacc tgcctgcaac agcagcagct tccggcagca
     1561 tggccctctg gtctgtgatg gcttccggga ctgcgaggat ggtcaggacg agcaaaactg
     1621 cactagaagc atcccatgca ccagtaggac ctttaaatgt ggcaatgaca tttgcttcag
     1681 gaagcaaaat gcacaatgtg atggtatagt ggactgtcca gatggaagtg acgaggaagg
     1741 ctgcggctgt agcaggagtt cttccttcct tcaccgaatc gttggtggtt ctgactccca
     1801 ggaggggacc tggccatggc aggtcagcct ccactttgtt ggatcagcct actgtggtgc
     1861 ctcagtcatc tccagggagt ggcttctctc tgcagcccat tgtttccatg gaaacaggct
     1921 gtctgacccc acgccatgga ctgctcacct tgggatgtat gtgcagggga atgccaagtt
     1981 tatctctcca gtgagaagga ttgtggtcca tgaatactac aacagccaga cttttgacta
     2041 tgacattgcc ttgctgcagc tcagcatagc ctggcctgaa accctgaaac agctcattca
     2101 accaatatgc attcctccag cgggccagaa agtgcgcagt ggggagaagt gctgggtgac
     2161 tggctggggg agaaggcatg aagcagatag taagggctcc ccggttttgc agcaagcgga
     2221 ggtagagctc atagatcaaa ccgtctgtgt ttccacctat gggatcatca cgtcgcgcat
     2281 gctctgtgca ggggttatgt ctggcaagag cgacgcctgc aaaggagatt caggaggacc
     2341 tttgtcttgt cgaagaaaga gtgatggaaa atggattctg actggcattg ttagctgggg
     2401 acatggatgt ggaagaccca attttcctgg tgtctacaca agggtgtcaa gctttgttcc
     2461 ctggattcat aagtatgtcc cttctctttt gtaactgtaa cagatggatt gttaactgtg
     2521 acttatatga ggatagatcc ttgaaaaaga atgtaagtat tatcaataaa attaatcatt
     2581 ttttc
//
