LOCUS       NM_016711               9893 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus tropomodulin 2 (Tmod2), transcript variant 2, mRNA.
ACCESSION   NM_016711 XM_001480872 XM_001480874 XM_001480878 XM_001480880
VERSION     NM_016711.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9893)
  AUTHORS   Mitra,A., Deats,S.P., Dickson,P.E., Zhu,J., Gardin,J., Nieman,B.J.,
            Henkelman,R.M., Tsai,N.P., Chesler,E.J., Zhang,Z.W. and Kumar,V.
  TITLE     Tmod2 Is a Regulator of Cocaine Responses through Control of
            Striatal and Cortical Excitability and Drug-Induced Plasticity
  JOURNAL   J Neurosci 44 (18), e1389232024 (2024)
   PUBMED   38508714
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9893)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 9893)
  AUTHORS   Roy,T.A., Bubier,J.A., Dickson,P.E., Wilcox,T.D., Ndukum,J.,
            Clark,J.W., Sukoff Rizzo,S.J., Crabbe,J.C., Denegre,J.M.,
            Svenson,K.L., Braun,R.E., Kumar,V., Murray,S.A., White,J.K.,
            Philip,V.M. and Chesler,E.J.
  TITLE     Discovery and validation of genes driving drug-intake and related
            behavioral traits in mice
  JOURNAL   Genes Brain Behav 23 (1), e12875 (2024)
   PUBMED   38164795
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 9893)
  AUTHORS   Soulez,M., Saba-El-Leil,M.K., Turgeon,B., Mathien,S., Coulombe,P.,
            Klinger,S., Rousseau,J., Levesque,K. and Meloche,S.
  TITLE     Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3
            in Perinatal Survival and Postnatal Growth Using New Genetically
            Engineered Mouse Models
  JOURNAL   Mol Cell Biol 39 (6), e00527-18 (2019)
   PUBMED   30642949
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9893)
  AUTHORS   Guillaud,L., Gray,K.T., Moroz,N., Pantazis,C., Pate,E. and
            Kostyukova,A.S.
  TITLE     Role of tropomodulin's leucine rich repeat domain in the formation
            of neurite-like processes
  JOURNAL   Biochemistry 53 (16), 2689-2700 (2014)
   PUBMED   24746171
  REMARK    GeneRIF: Role of Tmod2 protein's leucine rich repeat domain in the
            formation of neurite-like processes
REFERENCE   6  (bases 1 to 9893)
  AUTHORS   Sui,Z., Nowak,R.B., Bacconi,A., Kim,N.E., Liu,H., Li,J.,
            Wickrema,A., An,X.L. and Fowler,V.M.
  TITLE     Tropomodulin3-null mice are embryonic lethal with anemia due to
            impaired erythroid terminal differentiation in the fetal liver
  JOURNAL   Blood 123 (5), 758-767 (2014)
   PUBMED   24159174
REFERENCE   7  (bases 1 to 9893)
  AUTHORS   Coulpier,F., Le Crom,S., Maro,G.S., Manent,J., Giovannini,M.,
            Maciorowski,Z., Fischer,A., Gessler,M., Charnay,P. and Topilko,P.
  TITLE     Novel features of boundary cap cells revealed by the analysis of
            newly identified molecular markers
  JOURNAL   Glia 57 (13), 1450-1457 (2009)
   PUBMED   19243017
REFERENCE   8  (bases 1 to 9893)
  AUTHORS   Cox,P.R., Fowler,V., Xu,B., Sweatt,J.D., Paylor,R. and Zoghbi,H.Y.
  TITLE     Mice lacking Tropomodulin-2 show enhanced long-term potentiation,
            hyperactivity, and deficits in learning and memory
  JOURNAL   Mol Cell Neurosci 23 (1), 1-12 (2003)
   PUBMED   12799133
  REMARK    GeneRIF: Tmod2 plays a role in behavior, learning, memory, and
            synaptic plasticity.
REFERENCE   9  (bases 1 to 9893)
  AUTHORS   Conley,C.A., Fritz-Six,K.L., Almenar-Queralt,A. and Fowler,V.M.
  TITLE     Leiomodins: larger members of the tropomodulin (Tmod) gene family
  JOURNAL   Genomics 73 (2), 127-139 (2001)
   PUBMED   11318603
REFERENCE   10 (bases 1 to 9893)
  AUTHORS   Cox,P.R. and Zoghbi,H.Y.
  TITLE     Sequencing, expression analysis, and mapping of three unique human
            tropomodulin genes and their mouse orthologs
  JOURNAL   Genomics 63 (1), 97-107 (2000)
   PUBMED   10662549
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147581.1, AK079077.1 and AC123832.4.
            
            On or before Aug 8, 2008 this sequence version replaced
            XM_001480872.1, XM_001480874.1, XM_001480878.1, XM_001480880.1,
            NM_016711.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.74877.1, AK079077.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AK147581.1         3-159
            158-1925            AK079077.1         2-1769
            1926-2794           AK079077.1         1771-2639
            2795-9893           AC123832.4         85850-92948         c
FEATURES             Location/Qualifiers
     source          1..9893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 42.31 cM"
     gene            1..9893
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /note="tropomodulin 2"
                     /db_xref="GeneID:50876"
                     /db_xref="MGI:MGI:1355335"
     exon            1..302
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            303..495
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     CDS             370..1425
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /note="neuronal tropomodulin; neural tropomodulin"
                     /codon_start=1
                     /product="tropomodulin-2"
                     /protein_id="NP_057920.2"
                     /db_xref="CCDS:CCDS23345.1"
                     /db_xref="GeneID:50876"
                     /db_xref="MGI:MGI:1355335"
                     /translation="MALPFQKGLEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESA
                     TLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKE
                     KPVETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGEGRK
                     GPVRNVVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEF
                     AKSLETNTHVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVE
                     ALRENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAI
                     TKNNDLVRKKRVEGDRR"
     exon            496..652
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            653..775
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            776..862
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            863..993
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1101
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1245
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1390
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..9893
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1699
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /note="major polyA site"
     regulatory      9870..9875
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /note="hexamer: AATAAA"
     polyA_site      9893
                     /gene="Tmod2"
                     /gene_synonym="N-Tmod; NTMOD"
                     /note="major polyA site"
ORIGIN      
        1 gctctagatt ctaccggagg accctgcgag gccatcgcgt cattgggaga cgcagctgcg
       61 gcccgggcaa agggtcctgt ctcggagtgg ccaccgcgcg ccgccagaac tacgcttccc
      121 aggctgcccc gctgcagccg cgcgccccgc gccccgtgcc gcgccgcgcc cggccgggag
      181 ccgcctgttg atcgcagctc cagcctgggg ccacggcgcc gcccctgctg gtcggacccg
      241 ctcactcctg gctctaaggc tgctgggcag gaccttccgc ttcgggatgg gcacaagcaa
      301 agtggtagtg tgaagcctca ggaagctggc ccgctcgaag gtgtgtgaga aaggtgtatc
      361 ctggaaacca tggcgctccc ctttcaaaaa gggctggaga aatacaagaa catcgacgaa
      421 gacgagcttc ttggcaaact ctcagaagag gaactgaaac agttggaaaa tgttctagat
      481 gacctagatc ccgagagtgc aacgctacct gctggattcc gacagaaaga ccagacccag
      541 aaagcagcca ctggcccatt tgaccgagaa cacctgctca tgtacctgga gaaagaggct
      601 ttggaacaga aggacaggga ggactttgta cccttcacag gagaaaagaa agggagagtc
      661 tttatcccca aggaaaagcc tgtagaaact cggaaagaag agaaagtgac cctggaccca
      721 gaactggagg aagccttggc cagtgcctca gacactgaac tctacgacct tgcagctgtc
      781 ctcggagtcc acaatttgct caacaatccg aagtttgatg aagagacgac caacggcgaa
      841 ggtcgcaagg ggcctgtgag gaatgtcgtg aaaggtgaaa aggccaagcc agtatttgag
      901 gagccaccga accccacaaa tgtggaggca agcctgcagc agatgaaggc caacgacccc
      961 agcctgcagg aggtcaacct caacaacatt aagaacattc caattccaac cctgaaggaa
     1021 tttgcaaagt ctctggagac caacacccat gtgaagaagt tcagcctggc tgcaacccgc
     1081 agcaatgacc ctgtggccct tgcctttgca gagatgctga aagtcaacaa gaccttgaaa
     1141 agtctaaacg tagagtccaa ttttatcact ggcactggaa tcctggccct ggtggaagcg
     1201 ctgcgggaga atgacacctt gacggagatc aagattgaca accagaggca gcagttggga
     1261 acagctgtgg agatggagat cgcccagatg ctggaggaga actcaaggat cctcaagttt
     1321 gggtaccagt ttaccaagca agggccacgg acaagagtgg cagctgccat cacaaaaaat
     1381 aatgacctgg ttcgaaagaa gagagttgaa ggagacagga ggtaaagccc cactcaaagg
     1441 ggtgaagtct caccgtgcgg ccatccaaaa aaacataccc aaaatcctct tctccaccgg
     1501 accatttgat ccaaggctgt tcatttccgt taaccatatc catcataact ttaactgtta
     1561 ctccttttta gcgctaatta tttgtctgaa atatgtgtag cagtttgcct cgctcctgga
     1621 cacacctggt ggcttgcaca agtagggtga tacagatctt agacagtgac aacgctggag
     1681 atgatcttaa ccactttcat attgtagttt gtcttgcttt ctttcgtgaa ccgtttttag
     1741 tcatggaagg gacttagcat gtagcatgtg tttgtagctg atgacaaagt ggaggcctat
     1801 ctctgtttac atgcattgct ttgagctagg ccaggaacat ggggagtgtg tgctactgac
     1861 cacatgagaa gttagtattg ccaagctttc acaaattctc cgttaatttc agaaaaaaaa
     1921 aaaaatagtg tctctacatg cacatgccca actgatagat agatggtcag tgggatcttc
     1981 cttagaaagc actttaacgt agcactggca aagggactgt ttagtgcccc gtgagtatat
     2041 taacaagtca cacacttacc tttacttact gttaaacatg aatgaaacat atttgttaag
     2101 gtatgtggtc ctgggaattg tatccagaac cctgtgtgct aggcaagcac tctactcctg
     2161 agctacatct ccaacccaaa ttatatttaa aatgattctc taataggtaa ttatttacaa
     2221 agccgttgaa agactttcca ggtatgatgg gaaatttttt aaagtttaac caaaagaaaa
     2281 tttcaaaata gtacattccc acataaaata acaataacag cgtcttggga gctggagagc
     2341 tggctcagca gttaagagtg cttgctgctt tcccagaaga ccagagttca gcttcagcac
     2401 ctgtgtcaag cagctaactt gtatagctcc atcctcgggg gactctgatg cctccagcct
     2461 ctgagggcat ccacacatag gtatacatac cccctatata catacacatg attaaaaata
     2521 gatttaaaag ttatggtacc ttaatcaaag tttctgatac ataatgaatt tgacaaattt
     2581 taaaagcaat tgttgattca tctttagcat aaccagatca ccagctaaat tgtgggcatt
     2641 gtggttaatt atataggttt tttgggggtt ttttggtttt tttgtttttt gttttttgtt
     2701 ttgttttttt gtcacatgca attgcttctt tgccttttgg cttaaaatca agcattgatt
     2761 tttgtcatat atcacagtaa atccagctat ttgcaaacat taggttaaaa ggaattgtca
     2821 gttgctaaga tgtttgtcac ctcgaagaca gagcctgtga agacatgact gaagtgacca
     2881 tgaagtgact gatttcctag tacaacaact ggacagcata atgcaaattt aaggtaccaa
     2941 gtgatggaat gttttggccc aaaataatca cttttctctc ctgtcataga catcagccac
     3001 tgtcaggtac ctgtgttagc tgcccttctc actgctgtga ctaaatacct gacaaaagga
     3061 atataaggaa aagggggatt catcttggct cacagtttta ggttgccacc aactgtggca
     3121 gagaaggata gcagcaggag gatgagacag ttgtcacatc actgtcacag acaggaagca
     3181 aagagagatg aatgctgggg ctccgcccac tttcctttcc ccccttttta tttagtctgg
     3241 agttccagcc tatgggatgg tgctccccac attcagggtg agttctctct tcttggttaa
     3301 acttctctgg taacaccgta ggtgattcca aatcccatca agttgacaat gaagatcctg
     3361 tctagcatct cttgtccttc cttttcctct cctttcatga caaagcatcc ttcttgtttc
     3421 ccttctctct atgtcgctaa gtcagtggtt ctcaacctgt gggtcacaat ccctttggag
     3481 gttgaataac tctttcatgg aggtcactta agattattgg aaaacacaga tatttacatt
     3541 acaactcaaa acagtagtaa aattacagtc atgaagtagc aatgagataa atgtatggtt
     3601 gggggtcacc acaacatgag gaactgtatt aaaagcagta agaaggttga gaaccactgc
     3661 tctaagtcct ataaaggtga tgggaaacta tcagacaaga aagaacttgg agtcaggaac
     3721 cttgggaaaa aaaactggac acttagaggg agaaactgaa cacttactgt gctataaata
     3781 accacagcta aagcaaaaat tctcagacac acctcatttt cttggctcat ttttatactc
     3841 ttcaggacat aataaatagg gtattctgac attttttgag tcacccccaa gtgctttaac
     3901 ttaatacttt atctccctgt caatctaaaa atgtatttgt tttgttttat cccttaatct
     3961 gatctttcct tccttctcac ccacttgggt gtggtattga agccagtttg tataggtttg
     4021 ctggtttgtt cagttttcaa gaattcttta aattcttgct caaaattgcc ctgctaaaaa
     4081 ttaaggtgtg gtagcatgcc ctagtgatcc tagcacttgg agtggacgca agatcagtgt
     4141 tggctacaca gaaagtctga agccagcctg ctacctgaga cccctccctc aacttgaaca
     4201 tgaagtggct tgtacttaca gtgaaatcga tgatagtaaa ggcaaaacta tgctcttgag
     4261 attctttacg tctgttgtgc ctgtatggca tacagaccgc tgtgctatag cacaggtcgc
     4321 ccctgctctg ccagcattaa cttcttggcc atggtgagaa gagtccttgg gaattatcaa
     4381 tgtgtaagaa aatggctcca ttctttcctc tagattgttg gctgataagc agtcatccat
     4441 tctacctggg tgaaatgtat agggtgtatt ttaatcagaa tttttggtta ctctgttgcc
     4501 aaaggaagga tgctaagtgt ctttcctctc tctcagccac agacttcttt aagagcagag
     4561 tccctaacaa gcttcctttt cctgttttca ttcactctct tgcctccatt cctaagaagc
     4621 cctggccctg caaattattg tctgcagccc catattgtag agagtgggtt acaattgttg
     4681 acacaccctg gcaaaaagca agaaaaaaag tcatatttag atcatagata ttccttttta
     4741 taaggagtta ttaatactaa taagattgta gaacattatt tttaaattca tactggtttt
     4801 atcttataaa atgagtttat aagattatta ctaatcagct gttttatcat cgtggatttt
     4861 taactagcat gtaaagtgac atttccatca gcatttatat tttgaaggga actactagaa
     4921 gataaaatat acatcttagg gcatctatca aatccattta attagatgaa gacttcacct
     4981 cccacctgcc caaaatggac cattaatttc atcccgatga gacataatgt gtgtgaatta
     5041 tttttataag tatctgtttt gctagctagt gtgttgatgt attttctaat gcctgtatag
     5101 ctgtttggag ggagctcgtg tttgcctaag cctgctccct tcccctttac agttgtacag
     5161 gtccataagt gaaaactcac tcacctggac ttgacttgaa ggtttctgtg gctgatgtct
     5221 tgtcatgaca cctgtaaatg gatggctttt aggagattat ttgtcaagtt tagagatgct
     5281 aactagtcca gcagtacaaa tgcatctctc tgtctgcttg atgtgggcag cagaatttcc
     5341 ttcatcttta tcagcatgat caaatccctt gatttctctc tctctctctt tctctctgtc
     5401 tctctgtctc tctgtctctc tgtctctctc tctcgtgttt gtgttgtgtg tgtgctcgtg
     5461 tgcgagtgtg tttgtcagat atctaagtag gtatttggct acatctggac aactgattga
     5521 aggggaggct ctctccccag ttccacttcc cctccccctt tagagcagct gcagacccgg
     5581 gttcatggga aatgaccctg gagtctgcag tttctgtcac ctaccatcac atttcacagt
     5641 tgtgtagaga tgactcttga ggaaatcact ggattattcc ccatcagatc ttcctctata
     5701 cctaacgtga gactcatttc atacttagga gcatcaatta gcgcccttct tccatctctg
     5761 taggacacac tgtatataga cattttgtac ataatgatca ccaaatactg ttgtgaggta
     5821 tttggctgca tgtggaccat gagttgacgg gaccatgctt cccttgcccc tcccagggtt
     5881 gttgggggcc caggttagag aatcacatgc ctggaggggc aggtgctgct cacccatctt
     5941 tctgcacaca gctcatcttt cagtagaagt tcattcccat gttaaagctc aaaaaatatc
     6001 acagtgcctg tactcttggc accagttttc tcaaaggaag actggtatac caaaccatga
     6061 acagctgctt ctcttccatg tggagatgtg gcccctggtg ggcactagca ctatggaagc
     6121 cactgccttc tgaaaaactg ccacaagaca tttctcatga gcaaagcgta gacttggtgt
     6181 gaaagcgtca gcaggctctc gtgctcagac agtcgtggag agccggtaaa agtgtttgaa
     6241 cagacgtcct ttttcattgc tgaaaagtat tctgctctct cctcgatact ttgaaggagg
     6301 caagaaacat aagaattctg gactgagaag tctacacgtg tcttagggtt ggggtgacag
     6361 aatgcctttt tggaaggtag ctacgggggt tggggggtgt aatgacttac ttctcagttc
     6421 ccatgccctg ctactctgtt ctcacttaaa agactgaaag acacctaaag gaaaggtata
     6481 aaaacgtggt aaatgtcagg gtgatcccac tgggtaaatc acagagcagc cttgtggaac
     6541 tagctggcca gagaatagag cccagaacct cagttttcat tctttccttg ttcccccagt
     6601 tctagatctg acttgacgca gtgactcaag atccttacac aggggatggg ctggggactt
     6661 aatatttaaa ttagcttaat gcagagctca gttctgctca ctcctaactg cttgtccttc
     6721 agcctgacag caacaactga accatcagta gatatgtgcg caaagggttc caaattttat
     6781 gtccgtatcc tgggttctgt tctagaaaca gtacttgaat tggaggtcag gcctatctag
     6841 gacacactgt tggcttggag agggtgaaag agagggcatg aagtcatggg cagaaaagag
     6901 gaaccagcta accaggctta gttggctggg tcttgtggca gtcattcgga gcgtgctggc
     6961 tcagctggtt ggtatggtga acaggtgaca taccaacaga tttggaggct taatcccaat
     7021 cccattacca acacttagca ggtgtacgat catgggcaat tcatttaatt gcctgccaat
     7081 tatagactat atgggggacc aacaccggaa atggaatcaa gtgacctaaa cacttgactc
     7141 cacactctct tagctgggtg actttggggg agccacttgc tctccccagc ctaaagcccc
     7201 ccagctatta aaggggaaca atatcttcac taactacctc acagaattgt agtgagaaaa
     7261 tagaatcgta tgactggatg aaaacagcat agaaactaga aagcactgca cagaagtaga
     7321 tggctttagt cagctcgcta atgtttccca gagtctgttt tattctgacc aatggttcat
     7381 cttttggagt aggacaagaa gcatgggtac ggtgtaaggg actagaatta ttatacttta
     7441 catagagatg agaggtggat gacagggcag cgagtgttat atttcatgat agaaatgata
     7501 ggttattttt cctgggtcat tttgacccac tttataaagg gctggggagt aactcagtaa
     7561 ggcagtatgc ttgcctggaa tacacaaagt cctggatttg ttccccagca ctggatagat
     7621 aaactggatg ttatctagtt agtagcatta gcctgtaatc ccagcgctca aaaggtggag
     7681 gcaggagaac cagctcaaat tcatccttgg ctacatagtg aatttgagac cagcctggac
     7741 tacatgagat cctggcccaa ataataaaaa gctccttcgg aagttgtcac catgcttgta
     7801 gattctggcc ccaagagggg aactcagaca gttactaaga attgaggcaa gagcactact
     7861 gccttcctgt catcactaaa ggagatggag gctaggcaat aaaggtattg ctggcaacca
     7921 tagagagcat cgccctgcgg ctgcaagaat tttcgtgcgt agcatctgtg tactgggtac
     7981 cagcgctggc actggaggga agaaagctct ctggggctgc agctacctat caccagcgac
     8041 tcagccctcg tcagttcttt attttggcca agaaaagcat tggagcctgg cctcacaggg
     8101 atggtgtctc atcagtcctt gtatccatgg taccatctaa taaggtgcct tgtacatagt
     8161 agatgcttaa ttaatgttgc ttgtacagca ttgtcctcca gccctacaag aattatactc
     8221 tgtttacaac catgtgagat atacagacac acacacacac acacacacac acacacacac
     8281 acacttaatc atactgcttt ggatgccagc tgtatgtgac cttgggcaag gttttccatc
     8341 tatcttatgt tcttttcatc tataaaacag tgtattctct aaagtccctt ctagatccca
     8401 aacattacaa gcctgtgatt ctgaacacgg gtgggtaatg tacccacacc agctccagct
     8461 ctctccagga gccggcagct gtctgttcct tttcagcagc gtttgataac ttcagagtag
     8521 ctgtagagga gcagcctcat cagaaacgct gcttcagggc tggaaaggta gctcagtggt
     8581 agaacgttgc ctggcatgtg ggttcagttc tcagcactac aaaattaaac aaacaaacaa
     8641 acaaacttta aaagtcctgg gatgcttccc tcaaaagcag aaaggatatt tttaacatat
     8701 ctaatatttt tctccttaga atcagaggga aagaagggga agaaatacaa agaaaggaaa
     8761 gtgaccagga tggggttttt tttgtaggct tgtatttcat gtctgtgtat ttgcatgatt
     8821 tcattccaga agacaatcaa aggtgcactg tgtgttgcaa gaaactggcc caggatttaa
     8881 atttctgtgg acaccatcta gatgtgggta ggcagaaatt ggccaagcag agaaaggcga
     8941 tggataaaaa gtacacttcc tgagtaattt tactttagta ccaaatgtca gccgtgacaa
     9001 tctttattta aattattcta agccaggtat ggtagtgtcc acatgtaatc ccagcacttg
     9061 ggaggtgcag gagcagtgtc agaagttcaa ggtcatcttc tgaagcatag caagttcaag
     9121 accagcctgg gatacaagag acttagtctt aaattttgaa ataaatatat aagtaaaagt
     9181 aatttgtatc tctgctactt tctttttaag accaaaacta tgtacatgga aaagcatatt
     9241 tatattttaa gtaagccttt atcttaatcg tgtttcatgt tttttcagaa aacaagcaac
     9301 atttttcatt gcacataaac atgtaaaatt cttgcatgcc actggtcata atggcttacc
     9361 agttctctgc ctgtcaagtg tgactttatg tgtattgtta cctatattgt gttggagaga
     9421 ctaagggaca taatattctt gtaaacttgt cagcattgtt ggtaacattg tttatgtgag
     9481 cagatgctga agagccacag ggctttattt ttcatttgat attttttgag caaagctagg
     9541 tgattggtta attcactagg aatctaaaga ctaacttgcc ttttaaattt gaagttgaac
     9601 atcttgtgaa aagtaactgt gagataaaaa aatgtataga gtgtaaacta attttatcct
     9661 cataataagg aaacccattg tcccaccccc acccccccaa aaaaagggtg cgatttttgg
     9721 gccctttgga attagcaccc agagctaatg ttaagctaaa tagaaactgt tttaattaac
     9781 caagattttc ctgctttcaa agatgttatg tgttcacttg tgtctggaat gatagttgta
     9841 aattaaaatg taaaaagggg ggtggagtca ataaacttaa ctttaaatgt aaa
//
