LOCUS       NM_025915               1585 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 88 (Tmem88), mRNA.
ACCESSION   NM_025915
VERSION     NM_025915.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1585)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1585)
  AUTHORS   Li,L.Y., Yang,C.C., Li,S.W., Liu,Y.M., Li,H.D., Hu,S., Zhou,H.,
            Wang,J.L., Shen,H., Meng,X.M., Li,J. and Xu,T.
  TITLE     TMEM88 modulates the secretion of inflammatory factors by
            regulating YAP signaling pathway in alcoholic liver disease
  JOURNAL   Inflamm Res 69 (8), 789-800 (2020)
   PUBMED   32451556
  REMARK    GeneRIF: TMEM88 modulates the secretion of inflammatory factors by
            regulating YAP signaling pathway in alcoholic liver disease.
REFERENCE   3  (bases 1 to 1585)
  AUTHORS   Santos,R., Kawauchi,S., Jacobs,R.E., Lopez-Burks,M.E., Choi,H.,
            Wikenheiser,J., Hallgrimsson,B., Jamniczky,H.A., Fraser,S.E.,
            Lander,A.D. and Calof,A.L.
  TITLE     Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals
            Multiple Determinants of Risk for Congenital Heart Defects
  JOURNAL   PLoS Biol 14 (9), e2000197 (2016)
   PUBMED   27606604
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1585)
  AUTHORS   Lee,H.J., Finkelstein,D., Li,X., Wu,D., Shi,D.L. and Zheng,J.J.
  TITLE     Identification of transmembrane protein 88 (TMEM88) as a
            dishevelled-binding protein
  JOURNAL   J Biol Chem 285 (53), 41549-41556 (2010)
   PUBMED   21044957
  REMARK    GeneRIF: TMEM88 associates with Dvl proteins and regulates Wnt
            signaling in a context-dependent manner
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK161789.1 and AK045149.1.
            
            On Aug 1, 2009 this sequence version replaced NM_025915.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161789.1, AK045149.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1532              AK161789.1         2-1533
            1533-1582           AK045149.1         1534-1583
            1583-1585           AK161789.1         1582-1584
FEATURES             Location/Qualifiers
     source          1..1585
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.6 cM"
     gene            1..1585
                     /gene="Tmem88"
                     /gene_synonym="2600017H02Rik"
                     /note="transmembrane protein 88"
                     /db_xref="GeneID:67020"
                     /db_xref="MGI:MGI:1914270"
     exon            1..219
                     /gene="Tmem88"
                     /gene_synonym="2600017H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            220..1585
                     /gene="Tmem88"
                     /gene_synonym="2600017H02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      845..850
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem88"
                     /gene_synonym="2600017H02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      868
                     /gene="Tmem88"
                     /gene_synonym="2600017H02Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaccaggcca tggcggaggt ccccggagcc cagcgccccg ttctcgctgg cggcccagag
       61 cctcgggatc ccctagattg ctgggcctgt gcagtgctag taacggctca gaatctgctg
      121 gtggctgttt tcaatctcct cttgctggca ctggtgctgg ggaccatctt gctacctgct
      181 gtcatcatgt taggcttcgg ctttctctgc cactcccagt ttctgcgctc tcaggcaccc
      241 ctttgcacct cgcatctgcg ggacccaggc ttcacagccc tgttggtcac tggattccta
      301 ctgctcgtgc cgttgcttgt ccttgccctg gctacctacc gccgcctctg cctgcgcctc
      361 cgcctggccg actgcctcgt gccctacagc cgagccctct acaggcgccg gcgcatccca
      421 cagccgaagc aaatcccagt ctcaccaggt tctcggtctg ttcccacacc gggaaaggtc
      481 tgggtctgag gtgcttagag tcaagaatcc tgtcgattgc cctcctggtc tctcaaggac
      541 ttgaaacaag cccaggggtg tactgcccaa gccggttcct taccgcggcc tgagccggat
      601 cctaccatcc ctttgatgga acagctgaat gtggacgtag agctggcgaa aattcccatg
      661 tcccagaaac gtcattcaca tttgattcct gaacgtttgg gctggaccct gcacatcttc
      721 tttcccttcc ctattgtaaa taagagagct ggaccttgtg ccttcctttg ctggtgcagc
      781 tcctccaaaa tttacaggac tgagggacag ggctcacaca aataagagag aagccatcac
      841 aaataataaa aaaaaattat aaaatgaatg cactctgtga atacaggggt ggcacatatc
      901 caatcgctcc tgcactgggc tcaggagtag gaaacgaatc ctcaagacta caaatgggca
      961 aatcagagag catctctcag catcctgcct tttccttatc gcattagtcc attcttcctg
     1021 atcagacccc agagttgtct ggccctgacc ccaaagtcac ttccccatta atagcgcaga
     1081 gagggccttg tttcggctgc ctacccagct ccccttgggg acccgagccc gttctctgac
     1141 cccagcttaa aggaactgag tgttgccagg ccggggtggg aaacaatgga tcttccgggg
     1201 caggatgaca ccgcttcccg ctagaaactg aagcaggagc gtgggaggga agatggaggg
     1261 gcccacccta gggcctgctg ccttaagctc ctaacttgag ggagggtttg gttcttctag
     1321 gcattggggc aggttgagga agctcctgaa ctctgatgaa cctctaaggg tggggtgtgc
     1381 tagccctccc ctgacattgg acctacacac agacacaggc cactttggtc atagggttta
     1441 atggtctcaa agagaagtgc aattgtggtc agagatacgg gccccccgac agactctccc
     1501 tttggacttc aatagaaacg atgtggtgtc ctggtaccat ggccagaccc agcacacggg
     1561 gttcgcccgc agaaaatgaa tctgg
//
