LOCUS       NM_001374020            1653 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus transmembrane protein 80 (Tmem80), transcript variant
            4, mRNA.
ACCESSION   NM_001374020 XM_006536251
VERSION     NM_001374020.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1653)
  AUTHORS   Horiuchi,K., Perez-Cerezales,S., Papasaikas,P., Ramos-Ibeas,P.,
            Lopez-Cardona,A.P., Laguna-Barraza,R., Fonseca Balvis,N.,
            Pericuesta,E., Fernandez-Gonzalez,R., Planells,B., Viera,A.,
            Suja,J.A., Ross,P.J., Alen,F., Orio,L., Rodriguez de Fonseca,F.,
            Pintado,B., Valcarcel,J. and Gutierrez-Adan,A.
  TITLE     Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12
            Intron Splicing-Defective Zrsr1 Mutant Mice
  JOURNAL   Cell Rep 23 (1), 143-155 (2018)
   PUBMED   29617656
REFERENCE   2  (bases 1 to 1653)
  AUTHORS   Li,C., Jensen,V.L., Park,K., Kennedy,J., Garcia-Gonzalo,F.R.,
            Romani,M., De Mori,R., Bruel,A.L., Gaillard,D., Doray,B., Lopez,E.,
            Riviere,J.B., Faivre,L., Thauvin-Robinet,C., Reiter,J.F.,
            Blacque,O.E., Valente,E.M. and Leroux,M.R.
  TITLE     MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary
            Transition Zone
  JOURNAL   PLoS Biol 14 (3), e1002416 (2016)
   PUBMED   26982032
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163434.5.
            
            On Mar 9, 2022 this sequence version replaced NM_001374020.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189679.88258.1,
                                           SRR13422589.130995.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AC163434.5         124364-124497
            135-154             AC163434.5         129141-129160
            155-248             AC163434.5         129869-129962
            249-341             AC163434.5         130242-130334
            342-1653            AC163434.5         132076-133387
FEATURES             Location/Qualifiers
     source          1..1653
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 86.65 cM"
     gene            1..1653
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /note="transmembrane protein 80"
                     /db_xref="GeneID:71448"
                     /db_xref="MGI:MGI:1918698"
     exon            1..134
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..547
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /note="isoform 2 is encoded by transcript variant 4"
                     /codon_start=1
                     /product="transmembrane protein 80 isoform 2"
                     /protein_id="NP_001360949.1"
                     /db_xref="GeneID:71448"
                     /db_xref="MGI:MGI:1918698"
                     /translation="MAAVRPGRGSIKVLSSVPLQMLFHLSGLYSALYFLATLLMIVYK
                     SQVFSYPCNCLALDLVLLLLMGILKVAQLYLGTKGNLMEAEVPLAASLAFTAVGGLLS
                     VHFLLWQTLVLWMDSVLSTVLLVLHGLEAGLQVVVIADFIR"
     exon            135..154
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            155..248
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            249..341
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            342..1653
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1630..1635
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1653
                     /gene="Tmem80"
                     /gene_synonym="5530601I19Rik"
                     /note="major polyA site"
ORIGIN      
        1 agaatcgggc ctcggccgct gtcggacgct cgctgcaccg cgcggcggga ggagcgaaga
       61 tggcgggagg gtgcggccaa gaggctgctg ggattgtggc ggacccagcg gcaaaatggc
      121 ggccgtgcgg ccagggagag gctccatcaa ggtgctctcg tcagttcctc ttcagatgct
      181 gtttcacctc agtgggctgt actctgccct gtacttccta gctacactcc tgatgattgt
      241 atacaaaagt caggttttca gctatccttg taactgtctg gccctggatc tggttctctt
      301 gcttctgatg ggaattctca aagtagctca gctctaccta ggcacaaaag gcaacctgat
      361 ggaggctgaa gtgccactgg ctgccagcct ggcattcaca gcagtcggtg gcctcctttc
      421 tgttcacttc ctactctggc agaccttggt actgtggatg gactcggtcc tcagcaccgt
      481 tctcctggtg ctgcatgggc tggaggctgg cctgcaagtg gtggtcattg ctgacttcat
      541 caggtagatg gagcagggta acctgcacag cactgctcct tagccctcag caggttcctt
      601 ggcccagaca aggagactgt cttttttatt gatcgtctgt agatagttta tacatatttt
      661 ttgggggagg gggggagata ccagagccag ggagggacaa acttggaagc ttgaagatga
      721 ccatcatgga caggagccta gtgaatccca gaaatgtctt ctcaggtctt gtggctgggg
      781 tgctgactat agcgggacca ccatgatccc cagacagtag aaggtaaagc ctttcaggaa
      841 gtcaatggct aggggcagcc ctgcagctcc accttgtctc agccccagaa acatggcttc
      901 ctggcaggag tgtacaaact gtgctggtca ccaccctgtg tttgctcaca cacggattac
      961 tgagttctgt gcttcccacg ctggccctgg gtcttgttct gagagcctgt tgtacttagt
     1021 tgccagacct tggtccaggg ctgggatccc tctggagctg caggatggca gccttgtgtt
     1081 ccagtggccc tccaatttgg ctccccatca ggccagccct gaaatgaaac tgcttggttt
     1141 ccaaaaggaa acaaaagcaa atgtattcca ggtatggtgg cacacaaacc ttttagtccc
     1201 agcacccagg aggcaaagat gggcatatct ttgtgagttc aaagccagcc tacctggtct
     1261 acatagtgat ttgcaagtca cccagggtta cacggtgaga ccttgtcttt aaaaaaaaag
     1321 aaaaaagtat acagagagct gggtattatg accatctcag cccctttcat gggtgggggt
     1381 tggggaagtt gtagggagca gaagacagaa taaaagaacc gcttttagtc tatgattctg
     1441 ggagtcgcag tccaccaaac tgcagccttt gtagatgcca aatgaatctc atctcctgtt
     1501 tttcttttcc tagcccattt ttttctcaga aagtatttaa gcagtatttt ttttttacag
     1561 tttctttcat tctgttatgt gttttctgtt tatgtcgtta tgttcaaata tctagtttct
     1621 cttttaaaaa ataaataagt aattatgctg tca
//
