LOCUS       NM_001160363            1255 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus transmembrane protein 74B (Tmem74b), mRNA.
ACCESSION   NM_001160363 XM_130642 XM_904586
VERSION     NM_001160363.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1255)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928988.14.
            
            On Jan 10, 2022 this sequence version replaced NM_001160363.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077378.1, FO721671.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               AL928988.14        69023-69280
            259-1255            AL928988.14        73149-74145
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 74.83 cM"
     gene            1..1255
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /note="transmembrane protein 74B"
                     /db_xref="GeneID:108832"
                     /db_xref="MGI:MGI:1918629"
     exon            1..258
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            259..1255
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             300..998
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /codon_start=1
                     /product="transmembrane protein 74B"
                     /protein_id="NP_001153835.1"
                     /db_xref="CCDS:CCDS50748.1"
                     /db_xref="GeneID:108832"
                     /db_xref="MGI:MGI:1918629"
                     /translation="MASPPGLELKTLSNGPQVPRRAASQGPVAPPRMGVENACFFSEE
                     QETHFQNPGDARLGNAPSPPGGVPSLSRSQRDDLSLHSEEGPGLEPVSRPVDYGFVSA
                     LVFLVSGILLVVTAYAIPREARVNPDTVTAREMERLEMYYARLGSHLDKCIIAGLGLL
                     TVGGMLLSVLLMVSLCKGELYRRQTFVPGRGSRKTYGSINLRMRQLTGDGGQVLVENE
                     VVQVSETSYTTQGS"
     regulatory      1226..1231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /note="hexamer: AATACA"
     polyA_site      1255
                     /gene="Tmem74b"
                     /gene_synonym="5430405G05Rik"
                     /note="major polyA site"
ORIGIN      
        1 acccagcgcc gcgggctcct tgcctagggt ttccccggcc agcgtgcgcg ggcgagacag
       61 aggtggctct aggggcggtg ggggccgggc acccgcagcc ggctccctcc ccacgctaac
      121 tctcccggcg ccctcgcccg ccgcgggcgg agctcgatcg gcgacgctcc aggatcctcc
      181 gctcccgccc tgccttatcc cttccttctc ggagcccccc agcggccgac gcggtgcagc
      241 ccggcgcggc gcgagcagct gccaaggggc caagggatga gctggggtca ttctttccaa
      301 tggcatctcc ccctggtctg gaactgaaga cattgagcaa tggtccccag gttccaagga
      361 gagcggcctc gcagggcccc gtggcgccac ccaggatggg tgtggagaat gcctgcttct
      421 tctctgagga gcaggagact catttccaga accctgggga tgccagactg ggtaacgccc
      481 ccagtccccc tggaggtgtc ccctcactgt cccggtccca gcgggatgat ctttctttgc
      541 attcagagga gggaccaggc ctggaacctg tgagccgccc ggtggactat ggctttgttt
      601 ctgctctggt tttcttggtg agcggaatcc tcctggtggt gacagcatac gccatccccc
      661 gagaggcccg ggtcaaccct gacacagtga cagcaaggga gatggaacgc ctggagatgt
      721 actacgcccg cttgggctca catctggaca aatgcatcat tgcgggcctc gggctgctca
      781 cagtgggtgg catgctcctc tctgtgctgc tcatggtctc tctgtgcaag ggagagctgt
      841 accgcagaca gacctttgtc cccggcaggg gatccagaaa gacctatggc tccatcaacc
      901 tgcgtatgag gcagctcact ggggacggag gccaggtcct agtagagaat gaggttgttc
      961 aagtctcaga gaccagctat accactcagg gctcctaagt aagagtccac cctgtttttg
     1021 ctgctttagc tgcagagctt ggaggttccc aaaacctggg gcttcaaagt gacacccatg
     1081 gagggcattg tagagggagt tttggtgctg gggtgggggt agcctggggc ctggcttagg
     1141 cgtcactcag gcaaacactg ctgatgcgtt tgcagcttga ggttttcgca taaggctttg
     1201 tttgaggatg gcttctgctg ctaaaaatac attttggaaa ccactgctct tagaa
//
