LOCUS       NM_178768               3335 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 72 (Tmem72), mRNA.
ACCESSION   NM_178768
VERSION     NM_178768.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3335)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3335)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK085603.1.
            
            On Apr 5, 2007 this sequence version replaced NM_178768.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK085603.1, AK141578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3335              AK085603.1         2-3336
FEATURES             Location/Qualifiers
     source          1..3335
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 53.84 cM"
     gene            1..3335
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /note="transmembrane protein 72"
                     /db_xref="GeneID:319776"
                     /db_xref="MGI:MGI:2442707"
     exon            1..251
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..1009
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /codon_start=1
                     /product="transmembrane protein 72"
                     /protein_id="NP_848883.2"
                     /db_xref="CCDS:CCDS20462.1"
                     /db_xref="GeneID:319776"
                     /db_xref="MGI:MGI:2442707"
                     /translation="MKLQVFWTGLEYTCRLLGIATAAVLIGVGTETFLRGRFKSLAFY
                     LLFTGVTISVCEGTYFVAQLLAICFKCQPGSLAHRAKERAHWLGCFQKFLAYMLLSVA
                     CFLHPVLVWHVTIPGSMLIITGLAYFLLSKRKKKKAAPEVAPPTEQYTDPSSSVVSTT
                     GSGDTEQTYTFHEAFKEGPGSFFIHMKSILKGTKKPRVLQTQDTLMELALEPADSLAK
                     KKQVHFEDNVVRIIPSLTEGLGDSDSEPEETSSDTTPIIPPSQTPHFLPSLMATDLF"
     exon            252..318
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            319..390
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            391..530
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            531..3335
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2092..2097
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2113
                     /gene="Tmem72"
                     /gene_synonym="C230095G01Rik"
                     /note="major polyA site"
ORIGIN      
        1 attcacacct cagccagaca gcggaggcca gagctagttc agggaggctg agcccaaggc
       61 ccagggggcc ccccagccag cccccgcagc ctcctgcttg tgaggagcat ccagagcatc
      121 tcagatacag aggcatcttc gcagcctgcc cttctgggac tctgttcaca cccctggcac
      181 catgaagctc caggtattct ggactggact ggagtatacc tgccggctct tgggcatcgc
      241 tacggctgca gtgttgattg gagtgggcac cgagaccttc ctccgggggc ggttcaaaag
      301 cctggccttc tatctgctgt ttacaggagt caccatctct gtgtgtgaag ggacctactt
      361 tgtggctcaa ctcttggcca tctgcttcaa gtgccagccg gggtctctgg cacacagagc
      421 gaaggagagg gcccactggc tgggctgctt ccagaagttc ctcgcctaca tgctgctgtc
      481 agtggcctgc ttcctccacc ctgtcctggt ctggcatgtg accattccag gctccatgtt
      541 aatcatcact ggcctggcct acttcctgct gagcaagcga aagaaaaaaa aggctgctcc
      601 agaggtggca ccccccacag agcagtacac agacccttcc agcagcgtcg tgagcaccac
      661 aggctctggg gacactgagc aaacctatac tttccatgag gccttcaagg aggggcctgg
      721 ctccttcttt atccacatga agagcatcct aaaggggacc aagaagccac gtgtcctgca
      781 gacccaagat accctaatgg aactggcact ggagccggct gactccttgg ccaagaaaaa
      841 gcaggtacac tttgaagaca atgtggtcag aatcatccca tccctcactg aaggtctggg
      901 tgatagtgac agtgaaccag aagaaaccag ctctgacaca actcccatca tccctccctc
      961 ccagacccca cactttctgc cttctctcat ggccactgac ctgttctgag cttcttagct
     1021 agaggtctgc agatggatgg acctgccaga agagtcctaa tagccacagt ccctgcagag
     1081 aactcagggt ctccattggc cagctgttcg catcctagtg gtagctgggc attcagaaca
     1141 atgagatagt gtaccaagcc agatctgtgg tgacctccag caaggtacaa atgaagcttt
     1201 gacatgtgta atcaacatag tctccttgtc aaaaggtggg aaaagagacc atggcttcat
     1261 tctccacaag gctgctgacc caactttcta agccctaaag gaacagaaga catgagttca
     1321 cccttgcacc caacaaaggg ttcagccttc agcaagaact ctatggtatg ttttgcttgt
     1381 gatacaacct actggtgcca aaggcccagg gctatattag catcgtaagc aagattgctc
     1441 agggtagata tgagaaaaga agattcggat ctcaagtgag aacagcctgg cagtgggcta
     1501 cattctcagc atactctggg actgggctcg gcagcaggca tttcagaatc accaaggaaa
     1561 acaataccac tctgtgctca ctgccaggaa agctgaccag aagagcatct ctcattccag
     1621 aaggataact cagggcttcc tgccctcccc tcacttaccc cctatccaac agtatgagca
     1681 gtgttcagag tccaagtagg tggtatagat ggttcaatct aaaagggtct gagaacctgt
     1741 ggccatctgt agcagaaatg gctaggacat agcatggagt agtcattgta gttcaggccc
     1801 caagaagact gccccagaga gccacacagc atagggaagt acctctgcca tgcttagata
     1861 cgtgggagta gatcctctgt taagtagatg atcactcaaa atagacagga ggggaggaag
     1921 cagagggaag ggcacagggg agagggtagc gagcaggcag gcatggcggc atcctggaac
     1981 tacagaggtg gcagggaatt tgagttagat agttctcagt aaaaagttta gcaaagtatc
     2041 ttttctaaat agtatgtttg gtccacagga ttactgccag aaaaaaaaaa taataaaggc
     2101 atgttattcc tcatagctga cccccagtga gcgagcaaca gaaattaaga gtcctatagt
     2161 ttgtgtctga ggaggggacc cacttcaggg ctctctgatg ggtaagcctc aaatcttgta
     2221 ctttatagtc tagataagga agatgttcac ggtacaatga tcagcaccta tgacgtcgtt
     2281 ttgttttggt tttggttttg tcttgctttg ttttgttttg gaaatgtgtt gaaatgagac
     2341 accctagaag ctggtattag cctggtgctt agcacagcca gcatcccaga tggacagaac
     2401 actttttgaa atagaagatg cgttgctaag actgtgagga gtgaaggcag aaagcaagct
     2461 ggggcctgga gtaggtctca tccctcaggt caaaagatag gcagctgatg gatggccaag
     2521 ggggcttttc caatgaagga tgttagatag tgcagtcagg gaaaaataaa atatatggaa
     2581 tatggggcat gggtgggtat gtccttgtta ctacggggat ctcacggtga ggaagaacaa
     2641 gaaaacacta ccatgatacc atgaatttgt gtgaggtgag gccagtgcag acctaggaga
     2701 tggttcttaa ctccagattg caaggctgaa ggtcagggag cagagcttcc agcccgactg
     2761 aggccagagg ccagagggaa caaagccctt aaccaagagg agccaggtcc tctccctgtg
     2821 tctctctctc tgtattagtt actttctgtt gctgagataa aataccatga ccaaaagcac
     2881 ttaaggaaga aacagtgtgt gtgtcttaca gttcttacag agagctagag tccatgataa
     2941 cagagaagac ctggcatgca gcaggagcta gaggccagct ggccacattt catccacaca
     3001 ctgaaaatga ggccgagtgg ggagggcaat cgtgacatga ggctgtgaac cttcaaagcc
     3061 cacccctggg gatgtacttc ctccagtgag gttgcacctc ctaacgtctc cataactttc
     3121 ccaaacagca gcaccaacta gatgggtgac atttctcatt caaaccactg cagtctctca
     3181 tcagcttata tagtgttaga aatctttggt tcttggttgg ttggttggtt gattggttgg
     3241 ttggttggtt ggttggttgg ttagcttgct ttgcttttct taaacatcct taataagatg
     3301 tagtttgctg tcataaaatt gaccaagtta aacca
//
