LOCUS       NM_177861               3452 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus transmembrane protein 67 (Tmem67), transcript variant
            1, mRNA.
ACCESSION   NM_177861
VERSION     NM_177861.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3452)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3452)
  AUTHORS   Abrams,S.R. and Reiter,J.F.
  TITLE     Ciliary Hedgehog signaling regulates cell survival to build the
            facial midline
  JOURNAL   Elife 10, e68558 (2021)
   PUBMED   34672258
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3452)
  AUTHORS   Abdelhamed,Z.A., Abdelmottaleb,D.I., El-Asrag,M.E., Natarajan,S.,
            Wheway,G., Inglehearn,C.F., Toomes,C. and Johnson,C.A.
  TITLE     The ciliary Frizzled-like receptor Tmem67 regulates canonical
            Wnt/beta-catenin signalling in the developing cerebellum via Hoxb5
  JOURNAL   Sci Rep 9 (1), 5446 (2019)
   PUBMED   30931988
  REMARK    GeneRIF: The ciliary Frizzled-like receptor Tmem67 regulates
            canonical Wnt/beta-catenin signalling in the developing cerebellum
            via Hoxb5.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3452)
  AUTHORS   San Agustin,J.T., Klena,N., Granath,K., Panigrahy,A., Stewart,E.,
            Devine,W., Strittmatter,L., Jonassen,J.A., Liu,X., Lo,C.W. and
            Pazour,G.J.
  TITLE     Genetic link between renal birth defects and congenital heart
            disease
  JOURNAL   Nat Commun 7, 11103 (2016)
   PUBMED   27002738
  REMARK    Erratum:[Nat Commun. 2016 Jun 08;7:11910. doi:
            10.1038/ncomms11910.. PMID: 27273704]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3452)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   6  (bases 1 to 3452)
  AUTHORS   Wang,M., Bridges,J.P., Na,C.L., Xu,Y. and Weaver,T.E.
  TITLE     Meckel-Gruber syndrome protein MKS3 is required for endoplasmic
            reticulum-associated degradation of surfactant protein C
  JOURNAL   J Biol Chem 284 (48), 33377-33383 (2009)
   PUBMED   19815549
REFERENCE   7  (bases 1 to 3452)
  AUTHORS   Tammachote,R., Hommerding,C.J., Sinders,R.M., Miller,C.A.,
            Czarnecki,P.G., Leightner,A.C., Salisbury,J.L., Ward,C.J.,
            Torres,V.E., Gattone,V.H. 2nd and Harris,P.C.
  TITLE     Ciliary and centrosomal defects associated with mutation and
            depletion of the Meckel syndrome genes MKS1 and MKS3
  JOURNAL   Hum Mol Genet 18 (17), 3311-3323 (2009)
   PUBMED   19515853
REFERENCE   8  (bases 1 to 3452)
  AUTHORS   Dawe,H.R., Adams,M., Wheway,G., Szymanska,K., Logan,C.V.,
            Noegel,A.A., Gull,K. and Johnson,C.A.
  TITLE     Nesprin-2 interacts with meckelin and mediates ciliogenesis via
            remodelling of the actin cytoskeleton
  JOURNAL   J Cell Sci 122 (Pt 15), 2716-2726 (2009)
   PUBMED   19596800
REFERENCE   9  (bases 1 to 3452)
  AUTHORS   Dawe,H.R., Smith,U.M., Cullinane,A.R., Gerrelli,D., Cox,P.,
            Badano,J.L., Blair-Reid,S., Sriram,N., Katsanis,N.,
            Attie-Bitach,T., Afford,S.C., Copp,A.J., Kelly,D.A., Gull,K. and
            Johnson,C.A.
  TITLE     The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and
            are required for primary cilium formation
  JOURNAL   Hum Mol Genet 16 (2), 173-186 (2007)
   PUBMED   17185389
REFERENCE   10 (bases 1 to 3452)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772167.13.
            
            On Mar 29, 2019 this sequence version replaced NM_177861.4.
            
            Transcript Variant: This variant (1) encodes the supported protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045429.1, SRR1660817.194070.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-243               AL772167.13        12702-12944
            244-332             AL772167.13        14659-14747
            333-426             AL772167.13        20691-20784
            427-526             AL772167.13        23224-23323
            527-596             AL772167.13        24967-25036
            597-671             AL772167.13        25130-25204
            672-734             AL772167.13        26703-26765
            735-889             AL772167.13        30056-30210
            890-998             AL772167.13        30314-30422
            999-1076            AL772167.13        31168-31245
            1077-1142           AL772167.13        31726-31791
            1143-1299           AL772167.13        36829-36985
            1300-1423           AL772167.13        37501-37624
            1424-1529           AL772167.13        38799-38904
            1530-1586           AL772167.13        42082-42138
            1587-1685           AL772167.13        43245-43343
            1686-1784           AL772167.13        45530-45628
            1785-1871           AL772167.13        45827-45913
            1872-1971           AL772167.13        46885-46984
            1972-2111           AL772167.13        47073-47212
            2112-2252           AL772167.13        49131-49271
            2253-2333           AL772167.13        52769-52849
            2334-2450           AL772167.13        53345-53461
            2451-2567           AL772167.13        54540-54656
            2568-2672           AL772167.13        54760-54864
            2673-2775           AL772167.13        57092-57194
            2776-2918           AL772167.13        59882-60024
            2919-3452           AL772167.13        60767-61300
FEATURES             Location/Qualifiers
     source          1..3452
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 5.56 cM"
     gene            1..3452
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /note="transmembrane protein 67"
                     /db_xref="GeneID:329795"
                     /db_xref="MGI:MGI:1923928"
     exon            1..243
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..2999
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /note="meckelin; meckel syndrome type 3 protein homolog"
                     /codon_start=1
                     /product="meckelin precursor"
                     /protein_id="NP_808529.3"
                     /db_xref="CCDS:CCDS17974.1"
                     /db_xref="GeneID:329795"
                     /db_xref="MGI:MGI:1923928"
                     /translation="MVTRTRPVAAMAVRSRSSSRTGTAYLLLVLCEVSWAQIFSFPFR
                     RPETCDFNQYFDISALSCAPCGANQRRDALGTSCVCLPGYHMISNNGGPSIICKKCPE
                     NMKGVTKDGWDCISCPSGLTAEGKCHCPTGHILVERNVSGSLLAQATCELCDESENSF
                     TKANALGTRCVRCEPTFVNTSRSCSCSEPHTLTGGLCFSNTGNFHQRVISTARYGELG
                     MSLNSEWFAKYLQATAAACWTHANLTSCQALGNMCVMNMNSYDSTTLDACRLFHYIFE
                     STAGLISVHSVPFWRQNLPWLFYGDQPGLAPQVLSTTPLPTNFSFKGQNQLKFVAASY
                     DIRGNFIKWQPLEGGVLQLCPDTERRLDAAYAFGTTYQQNCEISLSKLLVDFSSPVFY
                     DVYLEYTDEEQHRYLWPIPVLNLNLQHNKLFVNQDSSSSKWLLTRRIFLVDAVSGREN
                     DLGNQPRVIRVATQISLSIRLVPNTKNGNIYTPLLTIAYSDIDIKNAHSQSAKISFSV
                     KYEMNQGDASVHTDIALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQTVMKFLLYYAG
                     DLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHK
                     FISQISIDIFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRK
                     INPLFQVLTTLFFLEVVGFKNLALMDSSSSLSRNPSDYTAPYSRILRYAVATAIWLVI
                     GIIQVVFFAAFYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYYIHGRSVHGHADTN
                     MEEMNMNLKREAENLCSQRGLVPNTDGQTFQIAVSSQMRQHYDRIHETLTRRNGPARL
                     LSSSGSTFEQSIKAYHAMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKS
                     IFYNDEGHSFSSVLYYGNEATLLIFDLLFFCVVDLACQDFVLASFLTYLQQEIFRFIR
                     NTVGQKNLATKTLVDERFLI"
     exon            244..332
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            333..426
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            427..526
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            527..596
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            597..671
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            672..734
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            735..889
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            890..998
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1076
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1142
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1299
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1423
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1529
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1586
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1685
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1784
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1871
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..1971
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2111
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2252
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2333
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2334..2450
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2567
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2568..2672
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2673..2775
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2918
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2919..3452
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3420..3425
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /note="hexamer: AATAAA"
     polyA_site      3449
                     /gene="Tmem67"
                     /gene_synonym="5330408M12Rik; B230117O07; b2b1163.1Clo;
                     b2b1291.1Clo"
                     /note="major polyA site"
ORIGIN      
        1 ggacccagga tatgggtacc atggtgacgc gtacaaggcc tgtggcggcc atggcggtca
       61 gatctcgttc ttcatcccgg actggcaccg cctaccttct cttagttctc tgcgaagtct
      121 catgggcaca aatcttctcc ttccctttcc ggcggcctga gacctgcgac ttcaaccagt
      181 actttgacat ctcggcgctc tcctgtgccc cctgtggcgc caaccagcgg cgggatgcac
      241 taggaacttc ctgtgtatgt ctaccaggat atcatatgat ctctaataat ggaggacctt
      301 ctattatttg taaaaagtgt ccagaaaaca tgaaaggcgt tactaaagat ggctgggact
      361 gcatttcttg tcctagtggc ttaactgctg aggggaagtg ccactgtccc actggccata
      421 tattagtgga aagaaatgtt agtgggtctt tgttagccca agcaacttgc gagctttgtg
      481 atgaaagtga aaactcattt acaaaagcca atgctttagg aaccaggtgt gtccgctgcg
      541 aaccaacatt tgtgaataca agcaggtcct gttcatgttc agagcctcac actttaacag
      601 gtggattatg tttcagcaac acagggaatt ttcatcaacg tgtaatttcc actgcacgtt
      661 atggagagct tggcatgtca ttaaattcag aatggtttgc caagtatttg caggcaacag
      721 cagctgcatg ctggactcac gccaacctga catcgtgcca agctcttgga aatatgtgcg
      781 tgatgaacat gaactcttac gactcgacca cactcgatgc ttgtcgactg ttccattaca
      841 tctttgaaag cactgctgga ttgatcagtg tgcattctgt tccattctgg agacagaacc
      901 ttccttggct gttctatgga gaccagccag gattggctcc tcaagttctc agtactacac
      961 ctcttcctac aaatttcagt tttaaaggac aaaaccagct gaagtttgtt gctgcttcct
     1021 atgatatacg aggaaacttc atcaaatggc aacctttaga aggtggtgtt ttacagcttt
     1081 gtccagacac tgagagaagg ctggatgcag cgtatgcttt tggaacaacg taccagcaaa
     1141 attgtgaaat ctctctctct aaactcctgg ttgacttcag cagccctgta ttttatgatg
     1201 tttacctcga atacactgat gaagagcagc accgttacct ttggcctatc ccagtgttaa
     1261 acctaaatct tcaacacaac aaactgtttg tgaaccaaga cagtagctcc agcaagtggc
     1321 ttctgactcg gcgcattttc ttagtggatg cagtaagtgg gcgagaaaat gacctaggaa
     1381 atcagccaag agtaattcga gttgctaccc agatttcact gagcatacgc cttgtaccca
     1441 acacaaaaaa tggaaacata tacactcccc tacttaccat tgcctacagt gacattgaca
     1501 tcaaaaatgc tcatagccag tctgcgaaga tttccttctc agtgaagtat gagatgaatc
     1561 aaggagacgc atctgtgcac acagatattg cgttgggtgt gttgggtggg ctggctgtgc
     1621 tatcatctct tttgaagaca gcgggatgga agaggcgcat cgggagcccc atgattgatt
     1681 tacagacagt tatgaaattc ctgctgtact atgctggtga tctggccaat gtgtttttta
     1741 tcatcacagt gggaacaggt ctttattggc ttattttctt caaagcacag aagtcagtct
     1801 ctgttttgct gccgatgcca gttcaggaag aacgtttcgt tacttatgtg gggtgcgcct
     1861 ttgctatgaa ggctctccag tttttacata agttcatatc ccagatttcc atagatatat
     1921 tctttattga ttgggaacgg ccgaaaggaa aagttcttaa agctgttgaa ggtgagggtg
     1981 gtgtgcggag tgccactgtt cctgtgagca tatggagaac gtatttcgtg gcaaatgaat
     2041 ggaatgagat tcagactgtg agaaaaatta atccactctt tcaagtgctt accacactct
     2101 tcttcttgga ggttgtggga ttcaaaaatt tagcgttaat ggattcatcc tccagccttt
     2161 ctagaaaccc atcagactac acagctcctt acagccgcat tctgagatat gccgtggcta
     2221 ctgctatctg gctggtgatt ggaataatac aggttgtttt ctttgctgcc ttttatgaga
     2281 gattcataga agacaaaatc cggcagtttg ttgacctgtg ctccatgagt aatgtgtcag
     2341 tgttcctgct gtcccacaga tgttttggat attacattca tgggaggtca gtccacggcc
     2401 atgcagacac taacatggag gaaatgaata tgaaccttaa gagagaggcg gaaaatttgt
     2461 gcagccaaag aggtttggtg cccaacacgg atgggcagac gtttcagatt gcagtttcta
     2521 gtcagatgag acaacactat gacaggattc atgagacttt aacaaggaga aatggccctg
     2581 ccagactgct gagttcgtcg gggagtactt ttgaacaaag catcaaagca taccacgcaa
     2641 tgaataagtt ccttggctct ttcattgacc acgttcataa ggaaatggat tactttataa
     2701 aagataagtt gcttcttgaa agaatccttg ggatggaatt catggagccc atggagaaga
     2761 gcatcttcta taatgatgaa ggccattctt tcagcagtgt gctgtattat gggaacgagg
     2821 ccacgctcct catctttgat ctgttgttct tctgtgttgt ggatttggct tgccaggact
     2881 ttgttttagc atccttcctc acatacctgc aacaagagat tttccgattt atccgaaata
     2941 cagtaggaca aaagaatttg gcaaccaaaa cactagtgga tgaaagattt ctgatctaat
     3001 ctgtgaatac agaacttaag gactcagtat aatatggcca agacttgatg ttgctatatt
     3061 ttttaaaact tgtaatacat attattctcc cattttttat ctacagaaag atttattttt
     3121 atagcttgtg aaatatgaaa tatagtaaaa acactctttc cccattatat gttgtattta
     3181 atttactaaa tagtacatta acactgacca ggaggcaaac atacaaacaa acaaaaacaa
     3241 acaagcccct cccagcccca ctttctgtgc tgtcccgggt cttgacagca ggctgaaact
     3301 tgccattgtt tcagaacatg acctgcctgc ttttcctcac ggtgtcaaat ctatttgatt
     3361 ctaggctcaa aactacagtt ctgctccgta ttttcatgtt ttatttatat tcaaggttaa
     3421 ataaatttca aaaggtattt tcaaatttac tt
//
