LOCUS       NM_182991               1493 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus transmembrane protein 59-like (Tmem59l), transcript
            variant 1, mRNA.
ACCESSION   NM_182991
VERSION     NM_182991.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1493)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1493)
  AUTHORS   Rutledge,E.A. and McMahon,A.P.
  TITLE     Mutational analysis of genes with ureteric progenitor cell-specific
            expression in branching morphogenesis of the mouse kidney
  JOURNAL   Dev Dyn 249 (6), 765-774 (2020)
   PUBMED   32017326
REFERENCE   3  (bases 1 to 1493)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   4  (bases 1 to 1493)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157774.5.
            
            On Feb 8, 2019 this sequence version replaced NM_182991.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056172.1, AK005155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164136
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-181               AC157774.5         160552-160732
            182-326             AC157774.5         161528-161672
            327-424             AC157774.5         161766-161863
            425-577             AC157774.5         162073-162225
            578-680             AC157774.5         162718-162820
            681-795             AC157774.5         163054-163168
            796-913             AC157774.5         163249-163366
            914-1493            AC157774.5         163466-164045
FEATURES             Location/Qualifiers
     source          1..1493
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.15 cM"
     gene            1..1493
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /note="transmembrane protein 59-like"
                     /db_xref="GeneID:67937"
                     /db_xref="MGI:MGI:1915187"
     exon            1..181
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1045
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; brain-specific membrane-anchored protein"
                     /codon_start=1
                     /product="transmembrane protein 59-like isoform 1
                     precursor"
                     /protein_id="NP_892036.1"
                     /db_xref="CCDS:CCDS22368.1"
                     /db_xref="GeneID:67937"
                     /db_xref="MGI:MGI:1915187"
                     /translation="MAAVALPLLLLLASLVTPTPARDPFAPQLGDTQRCQQRCRQHHP
                     GSPPAQPEPEGPSESPNNKAILISACERGCRLFSICRFVAKSSRPNATETECEAACTE
                     AYVKAAEQRACSEGCWGQIPEPETQLEQKDLALDPPRGRLSLRYLFSMLCSDLMSSAQ
                     GFLSSSWTYSLQTDNRKVVVFQTQPVAENFAFQGSHLQRVEVTWRRSHPKALELHMDP
                     VGPLDKVRKAKPRVKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSILIML
                     WLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESDWPLYPPLPPPAYEDSTPPYKLKLDL
                     TTL"
     exon            182..326
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            327..424
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..577
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            578..680
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            681..795
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            796..913
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1493
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1464..1469
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1483
                     /gene="Tmem59l"
                     /gene_synonym="5330410G16Rik"
                     /note="major polyA site"
ORIGIN      
        1 atcccagggc ccgcgctgcg catcttcagc catggctgcg gtagcattgc cgctgctgct
       61 gttgttggcg tcactggtca ccccaacccc agcgcgtgac cccttcgctc cgcagctcgg
      121 ggacactcag aggtgccagc agcggtgtcg ccagcaccac cctggctcgc ctcctgcgca
      181 gcctgagcca gagggtccct cagagtcccc gaataacaag gctatcctga tcagtgcttg
      241 tgagcgtggc tgtcggcttt tctccatctg ccgctttgtg gccaagagct ctaggcccaa
      301 tgccacagag acagaatgtg aagcagcctg cacagaagct tacgtgaagg cagcggagca
      361 acgggcctgc agtgaggggt gctggggcca gatccctgaa cctgagaccc agctggagca
      421 gaaggacttg gctttggacc cgcccagggg gcgcctctcc cttcggtacc tgttttccat
      481 gctctgtagc gacctgatga gttctgccca gggctttcta tcctcctcct ggacatattc
      541 ccttcagaca gacaaccgga aagtggtggt gttccagact cagcctgtag cagagaactt
      601 tgcattccaa gggagccatc tgcagcgagt ggaggtgacc tggaggaggt cccaccccaa
      661 ggccctagaa ctgcacatgg accctgtagg ccccttggac aaagtgagga aggctaagcc
      721 ccgagtgaag accagcaaag ccaaggtaga gtctgaggac caacaagaga gtgacttcct
      781 cagttgcatg tcccggcgct ccgggctgcc tcgatgggtc ctattctgct gtctcttcct
      841 gtccatcctg atcatgctct ggctgagttg ctgcactctg gtcaccacac caggccagca
      901 cctcaagttc cagcctctaa ctgcagaaca gcacaagggc ctcttggtgg agtctgactg
      961 gcccttatac ccacccctgc cgccgcctgc ctatgaggac agcacacctc cttacaagtt
     1021 gaagcttgat ttgaccacgc tgtaatctcc agcctactgc caagtgcagg ggcctcccta
     1081 cgttctgtac cctaaatccc aaggtcaggt tggggaccaa ccttgggctt atccaccccc
     1141 cagtcttccc tccctctctt gccagcacat cccttagtcc ccttgagaca agtggaccta
     1201 agtggccgag agaggagggt ctggcctcct tggcccccca tcttgctttc ccaggggctg
     1261 gcttattgac attcctcaca tgttctgagt atggaacctc atctgtgttg ctttttcttt
     1321 ctctgtgtcc tcactgtggg gctgaggtct caggggctcc cctctgctaa ggttccttcc
     1381 ctttgtctct ggaaacccaa ccccacaagg acagagtggt gagaactcct tcctgggagg
     1441 agataaggag atataaacct ttaaataaag tgaataaaaa atagggtggc tga
//
