LOCUS       NM_025452               1102 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 54 (Tmem54), transcript variant
            1, mRNA.
ACCESSION   NM_025452
VERSION     NM_025452.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1102)
  AUTHORS   Walentin,K., Hinze,C., Werth,M., Haase,N., Varma,S., Morell,R.,
            Aue,A., Potschke,E., Warburton,D., Qiu,A., Barasch,J., Purfurst,B.,
            Dieterich,C., Popova,E., Bader,M., Dechend,R., Staff,A.C.,
            Yurtdas,Z.Y., Kilic,E. and Schmidt-Ott,K.M.
  TITLE     A Grhl2-dependent gene network controls trophoblast branching
            morphogenesis
  JOURNAL   Development 142 (6), 1125-1136 (2015)
   PUBMED   25758223
REFERENCE   2  (bases 1 to 1102)
  AUTHORS   Hald,J., Galbo,T., Rescan,C., Radzikowski,L., Sprinkel,A.E.,
            Heimberg,H., Ahnfelt-Ronne,J., Jensen,J., Scharfmann,R.,
            Gradwohl,G., Kaestner,K.H., Stoeckert,C. Jr., Jensen,J.N. and
            Madsen,O.D.
  TITLE     Pancreatic islet and progenitor cell surface markers with cell
            sorting potential
  JOURNAL   Diabetologia 55 (1), 154-165 (2012)
   PUBMED   21947380
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606977.28, BY092384.1, AK008935.1 and BQ032787.1.
            
            On Feb 3, 2011 this sequence version replaced NM_025452.3.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019563.1, AK008935.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AL606977.28        51944-51961
            19-86               BY092384.1         1-68
            87-1043             AK008935.1         2-958
            1044-1102           BQ032787.1         1-59                c
FEATURES             Location/Qualifiers
     source          1..1102
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 62.86 cM"
     gene            1..1102
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /note="transmembrane protein 54"
                     /db_xref="GeneID:66260"
                     /db_xref="MGI:MGI:1913510"
     exon            1..202
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             187..846
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 54 isoform 1"
                     /protein_id="NP_079728.2"
                     /db_xref="CCDS:CCDS18681.1"
                     /db_xref="GeneID:66260"
                     /db_xref="MGI:MGI:1913510"
                     /translation="MCLRIGSLNVDEFRKVLMKTGLVLVVLGHVSFIAAAVLHGTMLR
                     FVATTSDAVVLQYCAVDILSVTSAIVVIVAGISTIVLSRYLPSTPLRWTVFSLSVACA
                     LLSLTCALGLLASIAVTFATKGRALLAACTFENPELPTLAPDCPFDPTRIYSSSLCLW
                     AISLIFCLAESMSAVRCAQLMHGLLELRPWWGKSCHHTIQASPEPLDAHDLLSCASSC
                     S"
     exon            203..396
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..456
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            457..645
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            646..780
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            781..1084
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1063..1068
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1084
                     /gene="Tmem54"
                     /gene_synonym="1810017F10Rik"
                     /note="major polyA site"
ORIGIN      
        1 gggtcgccca gccggtccga ccggcctcgg caacgcgcgc aggacgccgg gctgggcgac
       61 tgaggggtgc agggaaggga gccgccagga gcctgcttgg gcgggaagag gagcgcaggc
      121 cgcggaggag aaggatggaa gcgagacccc gctgagacca gcgcggggcc actggccggg
      181 atcaacatgt gtctgcgcat aggtagcctg aatgtggatg agttccggaa ggtgctgatg
      241 aagacgggtc tggtgctggt tgtgctgggt cacgtgagct tcattgcagc cgccgtgctc
      301 catggtacca tgcttcgctt cgtagccacc accagtgacg ctgtggttct acagtactgc
      361 gcagtggaca tcctctctgt cacctctgcc attgtggtca ttgttgcagg aatttcgacc
      421 atcgtcttgt cacgctacct ccccagcacc cccttgcgct ggaccgtgtt tagcttgagt
      481 gtggcctgtg ctcttctctc tctgacctgt gcccttggac tcctggcctc cattgcagtg
      541 accttcgcca ccaagggtag agcactattg gcggcctgta cttttgagaa ccctgaactc
      601 ccaacactgg cacctgactg tccttttgac cctactcgaa tttatagctc tagcctgtgc
      661 ctctgggcca tctctctcat attctgtctg gcggagagta tgtctgccgt gcgctgcgcc
      721 cagctcatgc atggactact ggaactaagg ccctggtggg ggaagagctg ccaccacacg
      781 atacaagcaa gcccagagcc cctggatgct catgacctat tgagctgcgc cagttcttgc
      841 agctgaccct ctgacacttc agcagcgcca tggctactga ggcacgtgac cacacctgta
      901 ttgacccgtg cccaaccagc catggaagtt tagtgggatc caggattcct agagcacgcc
      961 catgaaaagt caatggacta ctggggacgt gggagagggc tttgagcgcc ctcccctggc
     1021 caccgagtac aatgcactga aacaagactt tattttgaag ttattaaaaa gaaccaagat
     1081 gctcaaaaaa aaaaaaaaaa aa
//
