LOCUS       NM_019631               2698 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 45a (Tmem45a), mRNA.
ACCESSION   NM_019631
VERSION     NM_019631.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2698)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2698)
  AUTHORS   Weiner,C., Hecht,I., Kotlyar,A., Shoshany,N., Zadok,D., Elbaz,U.,
            Segev,F., Maytal,A., Hachmo,Y., Michiels,C., De Backer,O.,
            Shomron,N., Einan-Lifshitz,A. and Pras,E.
  TITLE     Association of Variants in TMEM45A With Keratoglobus
  JOURNAL   JAMA Ophthalmol 139 (10), 1089-1095 (2021)
   PUBMED   34410316
REFERENCE   3  (bases 1 to 2698)
  AUTHORS   Hayez,A., Roegiers,E., Malaisse,J., Balau,B., Sterpin,C.,
            Achouri,Y., De Rouvroit,C.L., Poumay,Y., Michiels,C. and De
            Backer,O.
  TITLE     TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization
            and Barrier Formation
  JOURNAL   PLoS One 11 (1), e0147069 (2016)
   PUBMED   26785122
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2698)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2698)
  AUTHORS   Williams,T.M., Williams,M.E., Kuick,R., Misek,D., McDonagh,K.,
            Hanash,S. and Innis,J.W.
  TITLE     Candidate downstream regulated genes of HOX group 13 transcription
            factors with and without monomeric DNA binding capability
  JOURNAL   Dev Biol 279 (2), 462-480 (2005)
   PUBMED   15733672
REFERENCE   6  (bases 1 to 2698)
  AUTHORS   MacLeod,C.L., Fong,A.M., Seal,B.S., Walls,L. and Wilkinson,M.F.
  TITLE     Isolation of novel complementary DNA clones from T lymphoma cells:
            one encodes a putative multiple membrane-spanning protein
  JOURNAL   Cell Growth Differ 1 (6), 271-279 (1990)
   PUBMED   1980600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK049837.1.
            
            On Apr 6, 2007 this sequence version replaced NM_019631.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049837.1, BC064715.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2698              AK049837.1         2-2699
FEATURES             Location/Qualifiers
     source          1..2698
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 34.22 cM"
     gene            1..2698
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /note="transmembrane protein 45a"
                     /db_xref="GeneID:56277"
                     /db_xref="MGI:MGI:1913122"
     exon            1..351
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     exon            352..544
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     CDS             355..1176
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /note="dermal papilla-derived protein 7 homolog; 19.5
                     mRNA"
                     /codon_start=1
                     /product="transmembrane protein 45A"
                     /protein_id="NP_062605.2"
                     /db_xref="CCDS:CCDS28226.1"
                     /db_xref="GeneID:56277"
                     /db_xref="MGI:MGI:1913122"
                     /translation="MGSFKGHALPGSFFFAMGFWWTMKNILKSVYKRQTRTCYLNSKT
                     LLRRTEIWEGVVVLLMSLTGIAGEQFISGGPALILHKDGQWNQILGWHHTTMYLFFGL
                     QGITQIICFTTNVLPLSSSKLMLSIAIFVETFMFYNHTHGREMIDIFVHQLLVFVGTF
                     SGLVAFLEFLVKNNALLELLRCSLLMFQGTWFWQMAFVLYPPSGSATWNLSDIQNKMF
                     LSMCFCWHYASILILIGVKYALANWLVKSRLRKGCTSEVGLLKHADREQESEEEV"
     exon            545..751
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     exon            752..936
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1082
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..2698
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1561..1566
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /note="hexamer: AATGAA"
     polyA_site      1595
                     /gene="Tmem45a"
                     /gene_synonym="C630002M10Rik; p19.5"
                     /note="major polyA site"
ORIGIN      
        1 gccccgccgg ggaaaccaga tgaagcacat ctggacagct gtgctgagaa agtttgtggg
       61 cctcttccag gcctgccacc cgcaaggcac gtcccccacg tagcctcctg ctagccactt
      121 actacttaat ttttttttcc ccaagaagca ataagcaacc cacgcttgaa tctttttctc
      181 tccctccccc ccacccccca tgtgaggcga ggccacatca cattcaacac agtttagttt
      241 tcatggggct ttgagatcaa aagaacagaa acagcaacca aagctcagct gccttctgat
      301 cctaactgac aaagtgggga gagtaaggtg tgcgcaaaca ggacaagttg ggtcatgggg
      361 agtttcaaag gacatgctct ccctgggagt ttcttcttcg ccatgggctt ttggtggact
      421 atgaagaaca tcctgaaatc tgtctacaaa aggcaaactc gaacctgcta ccttaactct
      481 aaaacattat tacgtcggac agagatttgg gaaggagttg ttgtgctttt aatgtctctc
      541 actggtatag ctggtgaaca gtttatctca ggaggacctg ccttgatctt gcataaagat
      601 ggccagtgga accagatcct gggctggcat cacacaacca tgtacttatt ctttgggcta
      661 cagggtataa cccaaatcat atgtttcact actaatgtac ttccactttc ctcaagcaag
      721 ttaatgttat caattgccat ctttgtggag acatttatgt tctacaacca cacacacggt
      781 cgggaaatga ttgacatttt tgtacaccaa cttctggtct tcgttggcac attttcgggt
      841 ctggttgcct tcttggagtt cctcgtaaag aacaacgcac ttctggagct cctgcggtgc
      901 agtctcctca tgtttcaagg aacctggttc tggcagatgg cgtttgtgct gtacccccct
      961 agtggaagtg ctacatggaa cctgtcagat attcaaaata aaatgtttct ctcaatgtgc
     1021 ttttgctggc attatgcatc aatccttatc ctcattggag taaaatatgc tttggccaac
     1081 tggttagtca agtctaggct gaggaagggc tgcacctcag aagttggact cctgaagcat
     1141 gctgaccgtg agcaagaatc agaagaagaa gtatgatctt gaagtctttc ttgataagcc
     1201 ttctcccttt gcgttgcctt tgttcatggc tttgtttctt gacctctggt ctcaagaaca
     1261 cttgtctgag gctgactcca tgctgtttgt acttccagtt ttgttaaagt gttggacttt
     1321 aagtatctta ctttcagctc tgaaagaacc atgagtgata aattcacttt ttacactgtg
     1381 catgccatgt aattcaagac caatcataat tgttttccaa agtttagttt cgtgtccatt
     1441 tattaaaaat atttttttta ttttccgggt agataccttc aagatttgtg gacttgccat
     1501 cactgtaata catgacgtgt tgacttgtat ttgtctatct tgttgccaca atggaaaata
     1561 aatgaatgca tgcaccttgg tgcagaaacc aaaaatcctc attttttttt tcttagtaaa
     1621 gtataccgca ccctcacatg atacagaaaa aaatctgcat gtacaaaatt ccatttcttt
     1681 gagacttttc tctatggaga gcttgatgca aaaggtagag cagaagtctt cttctgcatt
     1741 ttcaaaaagt aatgatgttg agacatatag tttcaaagat gacagagact aggagagagg
     1801 aattgtggta ttcacataac ctagcgttgg tcactgtgcc atttgctctg ttaatgaggt
     1861 aaaggattaa ataacaagcc tttctacaat cctaggtaaa aagtcttttt gccctgtggg
     1921 ccaagaaact cccagatgtg tgtaaaaaaa aaattatgca tattactctg gccctactgt
     1981 taaccactct ccatgtttct cataattagc tcatctttct tcttgtactt gatcttagtt
     2041 aaaaggccaa aaggtggttc ttcactctaa attaaagggg ttaaaatgac ttaataggca
     2101 tatggaccct ttcttactat cacatcctat gaatctcaaa tggaaacaag aagagaacta
     2161 aattaataca atgttacaca tcatggtgga cctgaagaat gagatgaata taatcttctt
     2221 gcccaaaaac tgggagcagt catcttgcta cataagattt taaaaagaca gatgtgagta
     2281 cccaaaaata tctcttgagc tgtaagtgag tgtactccag gatacaaggt accgatatgt
     2341 catggtcctc tgacgatcat gtgttctgct catgtctgtc ttagatttaa ggactctatt
     2401 ttagaccaac aacattctgt gactgccaca tttgagcttc aaaggaacca ggaatcagcc
     2461 tcagctagtt gagacaagtc actgatattg atgacagata aggttacacc cggaagtttg
     2521 aaagccaatg aatccagatt ttctgctgtt tttatgagaa tacagagatc actacttctc
     2581 caggttcaaa cccagagaat acaagtaaac ttcaacccag ggagttctca gaacatctga
     2641 gtctgagacc agttcaggaa tgcttcccta cagtgtctga aataaaaacc tttcttgc
//
