LOCUS       NM_019432               1014 bp    mRNA    linear   ROD 08-FEB-2025
DEFINITION  Mus musculus transmembrane protein 37 (Tmem37), mRNA.
ACCESSION   NM_019432
VERSION     NM_019432.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1014)
  AUTHORS   Butterfield,N.C., Curry,K.F., Steinberg,J., Dewhurst,H.,
            Komla-Ebri,D., Mannan,N.S., Adoum,A.T., Leitch,V.D., Logan,J.G.,
            Waung,J.A., Ghirardello,E., Southam,L., Youlten,S.E.,
            Wilkinson,J.M., McAninch,E.A., Vancollie,V.E., Kussy,F.,
            White,J.K., Lelliott,C.J., Adams,D.J., Jacques,R., Bianco,A.C.,
            Boyde,A., Zeggini,E., Croucher,P.I., Williams,G.R. and
            Bassett,J.H.D.
  TITLE     Accelerating functional gene discovery in osteoarthritis
  JOURNAL   Nat Commun 12 (1), 467 (2021)
   PUBMED   33473114
  REMARK    Erratum:[Nat Commun. 2021 May 28;12(1):3302. doi:
            10.1038/s41467-021-23768-8.. PMID: 34050183]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1014)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1014)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   5  (bases 1 to 1014)
  AUTHORS   Chu,P.J., Robertson,H.M. and Best,P.M.
  TITLE     Calcium channel gamma subunits provide insights into the evolution
            of this gene family
  JOURNAL   Gene 280 (1-2), 37-48 (2001)
   PUBMED   11738816
REFERENCE   6  (bases 1 to 1014)
  AUTHORS   Klugbauer,N., Dai,S., Specht,V., Lacinova,L., Marais,E., Bohn,G.
            and Hofmann,F.
  TITLE     A family of gamma-like calcium channel subunits
  JOURNAL   FEBS Lett 470 (2), 189-197 (2000)
   PUBMED   10734232
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC165443.5.
            
            On Oct 13, 2022 this sequence version replaced NM_019432.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024613.1, CX732161.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AC165443.5         161693-161757       c
            66-1014             AC165443.5         155357-156305       c
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 52.6 cM"
     gene            1..1014
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /note="transmembrane protein 37"
                     /db_xref="GeneID:170706"
                     /db_xref="MGI:MGI:2157899"
     exon            1..65
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..680
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /note="protein distantly related to to the gamma subunit
                     family; voltage-dependent calcium channel gamma
                     subunit-like protein; neuronal voltage-gated calcium
                     channel gamma-like subunit"
                     /codon_start=1
                     /product="voltage-dependent calcium channel gamma-like
                     subunit"
                     /protein_id="NP_062305.1"
                     /db_xref="CCDS:CCDS15229.1"
                     /db_xref="GeneID:170706"
                     /db_xref="MGI:MGI:2157899"
                     /translation="MTAIGAQAHKLLGLKRPHRSFFESFIRTLIIVCTALAVVLSSVS
                     ICDGHWLLVEDHLFGLWYFCTIGNHSEPHCLRDLSQAHMPGLAVGMGLARSVAAMAVV
                     AAIFGLEMLIVSQVCEDVRSRRKWAIGSYLLLVAFILSSGGLLTFIILLKNQINLLGF
                     TLMFWCEFTASFLFFLNAASGLHINSLTQPWDPPAGTLAYRKRGYDGTSLI"
     exon            66..1014
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      844..849
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /note="hexamer: ATTAAA"
     polyA_site      867
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /note="major polyA site"
     polyA_site      966
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
     regulatory      992..997
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
                     /note="hexamer: ATTACA"
     polyA_site      1014
                     /gene="Tmem37"
                     /gene_synonym="Pr; Pr1"
ORIGIN      
        1 gcgacagcta ggccaggcga cagcgctgcc taccagagcg cagcatgacg gccatcggcg
       61 cgcaggccca caagctgttg ggccttaaga ggccccaccg gtctttcttt gagtccttca
      121 tccggacact catcatcgtg tgcactgccc tggctgtggt cctttcttca gtctccatct
      181 gcgatggcca ctggctccta gtggaggatc atctctttgg gctgtggtac ttctgcacca
      241 tcggcaacca cagtgaacca cactgtctga gagacctgag ccaggcccat atgcccgggc
      301 tggctgtagg catgggccta gcacgcagtg tggccgccat ggcagtggtg gctgccatct
      361 tcggcttgga gatgctcatt gtgtcccagg tgtgtgaaga tgtccgctca cggcgcaagt
      421 gggccatcgg ttcctacctc ctcctggttg cctttatcct ctcctctggg ggcctcctca
      481 ccttcatcat cctgctcaag aatcagatca acctcctggg cttcaccctg atgttctggt
      541 gtgaattcac tgcctccttc ctcttcttcc tcaatgccgc cagcggcctt cacatcaaca
      601 gcctcactca gccctgggac cctccagcag ggaccctggc ttacagaaag cgaggttatg
      661 atgggacttc tctgatatag gacctctggc tgagattgaa taggacaacc aatgaccttg
      721 acactgcctc ttaggcactt agctctagca atgccctgga agtctcttca gctgagctcc
      781 agggcaaagg cagaagggtg cctctgtacg acggcacagt gagctggata ggttagtcat
      841 gctattaaaa tctcaatttg aaagtaagga gagtatccta aaatgtcttc ctacggtgtt
      901 ttcttccctg actggaatag ggtttgaaag agaccaaaag tcagttccag aatggctgcc
      961 cagctacgta gggctcatgc ctgtttcatt gattacagtg ggatgtgggc tgga
//
