LOCUS       NM_026982                836 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus transmembrane protein 256 (Tmem256), transcript
            variant 1, mRNA.
ACCESSION   NM_026982 XM_001001731 XM_001001740 XM_001003201 XM_001004626
            XM_109683 XM_909001
VERSION     NM_026982.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 836)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 836)
  AUTHORS   West,D.B., Engelhard,E.K., Adkisson,M., Nava,A.J., Kirov,J.V.,
            Cipollone,A., Willis,B., Rapp,J., de Jong,P.J. and Lloyd,K.C.
  TITLE     Transcriptome Analysis of Targeted Mouse Mutations Reveals the
            Topography of Local Changes in Gene Expression
  JOURNAL   PLoS Genet 12 (2), e1005691 (2016)
   PUBMED   26839965
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 836)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 836)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603707.5.
            
            On Mar 24, 2023 this sequence version replaced NM_026982.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY782043.1, BX527766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AL603707.5         217778-217878
            102-133             AL603707.5         218149-218180
            134-214             AL603707.5         218417-218497
            215-836             AL603707.5         218595-219216
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.89 cM"
     gene            1..836
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /note="transmembrane protein 256"
                     /db_xref="GeneID:69186"
                     /db_xref="MGI:MGI:1916436"
     exon            1..101
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..358
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /note="UPF0451 protein C17orf61 homolog"
                     /codon_start=1
                     /product="transmembrane protein 256 precursor"
                     /protein_id="NP_081258.1"
                     /db_xref="CCDS:CCDS24915.1"
                     /db_xref="GeneID:69186"
                     /db_xref="MGI:MGI:1916436"
                     /translation="MAGVGAAFRRLGALSGAGALGLASYGAHGAQFPDAYGKELFDKA
                     NKHHFLHSLALLGVPSCRKPVWAGLLLASGTTLFCTSFYYQALSGDTSIQTLGPVGGS
                     LLILGWLALAF"
     exon            102..133
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            134..214
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            215..836
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      447..452
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      467
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /note="major polyA site"
     regulatory      814..819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
                     /note="hexamer: AACAAA"
     polyA_site      836
                     /gene="Tmem256"
                     /gene_synonym="1810027O10Rik; 3110009M16Rik"
ORIGIN      
        1 gtgaccaccc acagctatgg ccggggtagg ggctgctttc cgccgcctag gtgccttgtc
       61 cggagctggg gccttgggtt tggcctccta cggggcacac ggcgctcagt ttccggatgc
      121 ctacgggaag gagctctttg acaaggccaa caaacaccac tttttgcaca gcctggccct
      181 gttaggggta ccctcttgca gaaaacctgt ctgggcagga ttactgttag cttctggaac
      241 taccttattc tgcaccagct tctactacca ggctctgagt ggagacacca gcatccagac
      301 tctggggcct gtgggaggga gcctgctaat cttgggctgg cttgccttgg ctttttgaag
      361 tctcttgttt aagcgcccag tcctggcctt tctgggtaat tgggcgcaga gggaaggagc
      421 caatgttgaa gcagaaaaga aattaaaaga aaaaggcata taaagaactt tggtgtcttt
      481 attcatctaa cattgagcaa gggagggcag agagtctacc tttgaatttg catttctaac
      541 tacaaagatc ctctggttct ggaattccaa tctttacaag gtgttgtaat tgtgtgtagg
      601 gctcataaag agcgcttgaa ctaatggagc ctcttaccta aagagcacat gaggggctgg
      661 agagatggct cagtggttaa gagcgccgac tgctgatcct gagttcaaat cccagcaact
      721 acatggtggc tcacaaccat ccgttatgag atctgacgct ctcttctggt gcatctgaag
      781 tcagctacag tgtacttagc ttttataata ataaacaaat ctttttttaa aaaaca
//
