LOCUS       NM_026679               2149 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 254 (Tmem254), transcript
            variant 1, mRNA.
ACCESSION   NM_026679
VERSION     NM_026679.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2149)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2149)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2149)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   4  (bases 1 to 2149)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
REFERENCE   5  (bases 1 to 2149)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY784109.1, AK002441.1, AC165285.2 and AV172143.1.
            
            On Jun 18, 2010 this sequence version replaced NM_026679.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the shorter isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002441.1, BC031854.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                BY784109.1         31-100
            71-1427             AK002441.1         2-1358
            1428-2124           AC165285.2         105524-106220       c
            2125-2149           AV172143.1         220-244
FEATURES             Location/Qualifiers
     source          1..2149
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 15.49 cM"
     gene            1..2149
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /note="transmembrane protein 254"
                     /db_xref="GeneID:66039"
                     /db_xref="MGI:MGI:1196450"
     exon            1..375
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..660
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transmembrane protein C10orf57 homolog; tranmembrane
                     protein 254a; transmembrane protein 254c; transmembrane
                     protein 254b; transmembrane protein 254a"
                     /codon_start=1
                     /product="transmembrane protein 254 isoform 1"
                     /protein_id="NP_080955.1"
                     /db_xref="CCDS:CCDS49420.1"
                     /db_xref="GeneID:66039"
                     /db_xref="MGI:MGI:1196450"
                     /translation="MGTATGAGYFQRGSLFWFTVITVSFGYYTWAVFWPQSIPYQSLG
                     PLGPFTKYLVDHYHTFLRNGYWLAWLIHVGESLYALVLCKRKGITDVQAQLLWFLQTF
                     LFGVASLSILIAYRSKRQKHN"
     exon            376..479
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /inference="alignment:Splign:2.1.0"
     exon            480..539
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /inference="alignment:Splign:2.1.0"
     exon            540..2149
                     /gene="Tmem254"
                     /gene_synonym="0610008K04Rik; 0610010A22Rik; D14Ertd449e;
                     Gm10395; Gm9746; Tmem254a; Tmem254b; Tmem254c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaatggct ccgcccaaat gaggagagca aatgaggagg cgcaatgctc cgcaccgtct
       61 caactcactg aaatggctcg gaaacttgac tcgccattat caaggaggca aaacagcggc
      121 tattctaact gaaattgaga ggtgcctcct gcaccggaaa agaccgagac tcggtcccca
      181 gatcaccgca gccaaaacct tccgggtctg gtgcacagga aaccgctcgc cccgcccggg
      241 ccaccttgca ctggatgcaa gtgaccatcc ggtgggatcg ctgcagcgat ggggacggcc
      301 acaggcgccg gctacttcca gaggggcagc ttgttctggt tcacagtcat caccgtctcc
      361 ttcggctact acacgtgggc tgtcttctgg cctcagagca tcccttatca gagccttggg
      421 cccctgggtc ccttcacgaa gtatttggtg gaccactatc acaccttcct aaggaatggg
      481 tattggcttg cttggctaat tcatgtggga gagtccttgt atgccttggt tttatgcaag
      541 cgtaaaggaa tcacagacgt ccaggcccag ctcctctggt tcctacagac ttttctgttt
      601 ggtgtagcct ctctctccat cctgattgct tacagatcaa agcgccaaaa acacaattaa
      661 aaaagagaga gcaagtttct ctccacctct tcaagccctc ctttcagtgg ggccctgggt
      721 accatgatgg cctccctgtc ttctaggcag tgtctgtcga agaacctgcc tgagaccctc
      781 tggttactat tattttggtg ctctgactaa ccttggatag atctttcttg tttaagaaag
      841 aaataagaaa gaccctgccc ttccagctct gcagacctcc tgcctgaaga tggcctcagg
      901 ccactttcct gaggtcctta gctgagtcat tttcctgcct tttggctaaa acacactaga
      961 tttatttgtg ggtgcaccta tgctctgtgt ggtggtttga atatgcttgg cccatgggaa
     1021 gtggcactac taggaggtat gtggccttgt tagaggaaat gggtcgctgt ggaggccaga
     1081 ttttgaggtc tcatatattt gctcaagtct agccagtgtg aaacggtctc cttccgctgc
     1141 ctttagatca agatgtagaa ctctcagctc cttttccgga tcatgttcgc ctggacactg
     1201 ccatgcttcc taccatgatg ataatggact gagcctccga aattataaac cagccccaat
     1261 taaatgttcc cctttgtaag agttctcttg atcgtgatgt ctctttacaa caatgaaatt
     1321 cctaattaag acactcactc cctgctctga ctagcacccc ctcccctcct ccccactgat
     1381 atcttagctt ctacccccaa actttttctg gttctggacc aagataaagt aaaacttcca
     1441 cataacatca gttccacatg catctgagtt cttttggttt ctcctgaacg tgctattggt
     1501 attgggggtg gggtaagtgt gtttattaat tggaattacc tgttaggttt ttttcttctc
     1561 ttcctctctc tgtagtgtac ccttgatatc cataatgctg ataaagcctc aaaggtgaag
     1621 ctacaccaga aggtgtactc agaactcaga gaagtccaac ttccctccct aaccctctca
     1681 gctcagtccc accccacgcc ccataattta ggggaggggt ttaaaatgtg tgtaacagac
     1741 agggcctaag gagatggaaa agacaaaagg aacgtcacct tttatagaca aaagtggaca
     1801 gaggctctgt cataaaatac cctaggttgg tgtgggtgtc ccttcctagg attataaaga
     1861 atcccataca cagtgtcttc tgtagagaca gctggtcaaa gtatgaaata aatgactgtg
     1921 gattgcgtgt ccttgaacgg gacatctata tgacctccaa agctaaggga aaattaaggc
     1981 agaggggaca gagagaatga aagagccgtc catagatgtg agggcaatct ggttttaaca
     2041 tctgtcaccc cattggttgc cagggtttat agctttctat ttcaacactg tctattttac
     2101 cacctctaac cgtatagaat aataaacccc caaattaaat actctcttc
//
