LOCUS       NM_027854               3669 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 248 (Tmem248), transcript
            variant 1, mRNA.
ACCESSION   NM_027854
VERSION     NM_027854.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3669)
  AUTHORS   West,D.B., Engelhard,E.K., Adkisson,M., Nava,A.J., Kirov,J.V.,
            Cipollone,A., Willis,B., Rapp,J., de Jong,P.J. and Lloyd,K.C.
  TITLE     Transcriptome Analysis of Targeted Mouse Mutations Reveals the
            Topography of Local Changes in Gene Expression
  JOURNAL   PLoS Genet 12 (2), e1005691 (2016)
   PUBMED   26839965
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3669)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113029.23, CN526906.1 and AK142176.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK171152.1, BC033455.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AC113029.23        43785-43785
            2-173               CN526906.1         27-198
            174-1724            AK142176.1         162-1712
            1725-3669           AC113029.23        63271-65215
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 68.91 cM"
     gene            1..3669
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /note="transmembrane protein 248"
                     /db_xref="GeneID:71667"
                     /db_xref="MGI:MGI:1918917"
     exon            1..238
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            239..416
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            417..702
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            703..853
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1037
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1181
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..3669
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1357..1362
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /note="hexamer: TATAAA"
     polyA_site      1376
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /note="major polyA site"
     regulatory      3551..3556
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3570
                     /gene="Tmem248"
                     /gene_synonym="0610007L01Rik; A930023A16Rik;
                     G430067H08Rik"
ORIGIN      
        1 gacgtggttt tctgccttca cccggaaagc ccggcgttcg cagcgcgcgg agccggcgtc
       61 ccgttggcgc gctctggcct ggcttcgggt cgtcgcttcg gccccgagga gccgctcgct
      121 gtctccggag cggcggagag gatggtgcgg ggcagcccgg ggcccgccgc gcgccgccgc
      181 gagtgaacag ggccaggccg cgggcgtccg cgggctcgag ccgccagtct gcggggcggt
      241 tgccgctggt gggaagcatg ttcagtatca accccctgga gaacctgaag ctgtacatca
      301 gcagccggcc gcccttggtg gtttttatga tcagtgtcag cgccatggcc atcgccttcc
      361 tcaccctggg ctacttcttc aagatcaagg agattaagtc cccagaaatg gctgaggatt
      421 ggaatacttt tctgctccgg tttaatgatt tggacttgtg tgtatcagaa aacgagacac
      481 tgaagcatct ctccaacgat accaccacac cagagagcac catgaccgtc gggcaggcca
      541 gatcgtctac ccagccgccc cagtccctgg aggagtcagg ccccatcaat atttcagtgg
      601 ccattacctt gaccttggac cctctcaagc cctttggagg gtactctcga aatgttacac
      661 acctgtactc caccatcctc gggcatcaga ttggattgtc aggcagggaa gcccacgagg
      721 agatcaacat caccttcacc ctgcctgctg cctggaacgc cgatgactgt gccctccatg
      781 gccactgtga gcaggcggtg ttcacagcat gcatgaccct cacagctgcc cccggagtct
      841 tccccgtcac tgttcagcca cctcactgta tccccgacac atacagcaac gccacgctct
      901 ggtacaagat cttcacaact gccagagatg ccaacacgaa atatgctcaa gactacaatc
      961 ctttctggtg ttataagggt gccattggga aagtctacca tgctttaaat cccaaactca
     1021 ctgttgttgt tccagatgac gaccgctcat taataaacct gcatctcatg cacaccagtt
     1081 acttcctttt cgtgatggtg ataacgatgt tctgctatgc agtcatcaaa ggcagaccca
     1141 gcaaactgcg gcagagcaat cctgaatttt gccctgagaa ggtggctctg gctgacgcct
     1201 aatcctacag ctccccattt tctgagagac caagaaccat gatcattgcc tgctgaatcg
     1261 gccagggcct ggccactctg tgaatacatg atcttgcaat gttgggttat tccagccaaa
     1321 gacatttcaa gtgcctgtaa ctgatttgtc catatttata aacactgatc tggaaattgg
     1381 tcctgtgatg cacgtgcttt gccctggatg cacctgaact cgtccccctc gtcgaggggc
     1441 aggagggcat ggacatgggc ttcttcacgg agagccaggg cgtgtgggga tcttgccaga
     1501 gctgagctga gcagctcgtg ttccagcgcc agtggggccg aggtttgctg tggttcttgt
     1561 ttcagactgg cgtgctgagt gctggaagct gtttgcacct ttgtcaggac actgcgtttc
     1621 agaagccact gttccctctg gtggctttta catgtcggtg gctggcatac catatagtaa
     1681 cagcagtaat tctgtctcag tgtgcttgca aggaaacttt tcttataaag agaaaaaaaa
     1741 gttacaattt actactgccc tagttaggac agacatgctt gtctctccta ggtaaaaggt
     1801 caggtccccg agtcatttct gtagtgaaga gcagagttcc gtgtctacac tggcaactag
     1861 gaactggggt gctctgctcc cgtttgctcc tgggaggggc gttctcctgg cttgagaagt
     1921 agctgtgtag tgaaggcaca gggttgtgtg ggtgactaac ttcacacggc agaagagatg
     1981 ttgctctaat gctcacaaac agggcttgct ctttttttta tttttagagg aaatacattt
     2041 tctttttaat tttttttttt ttgcattcat ttctatacat cacacatctc caggagaatg
     2101 cacattatag gtatgtaatg tggaaccgac actggggaga tctgaaggaa gaaggcatga
     2161 ggcactctct gatggcttgc tagtcaaaac tggaaggatt ttccttagga caggtgtgac
     2221 cttctggtcc ctctgtccca ttgccctctc gtattccatt taaaaaagtc attcatgatc
     2281 ctttccaccc gctctctgta ttttcaatgt ttttctctca gcgccttgcc ttaacaatcc
     2341 ccagacagtg ttctctcaag cagtgttcca gacttgttgg gtgtgaagat aaatgcatgt
     2401 aagagcagcc ctttggaggc tgaggcagga gaatctcaag ttcagggcca gcctgggcca
     2461 catactgata ccctgtctct caaagggaga aaaattactt aggtatgtca gcacttttgt
     2521 cctgtaactg tagatctgtc tcaattgaag ttaactcact atattcggaa acttactggc
     2581 ctagagaatt ttatcccagg cattcttaga tggaaaacaa tacttttgtt ttttcttcta
     2641 aattgaagct tgttaaaata atcactgtag ttatgtggta cactagtatt tcttaaagca
     2701 gaggtgagtt gcggataagg tggataatat gtgactttag tctagtcttc tctgagactt
     2761 tgagaccctt ggcttggctg gtataagtgt gtcatccgga ccaccaaact tcagattaag
     2821 ctgttactga gtgagacacg agaagaatgg tgttcgctgg tctgtcggct gtgttcctct
     2881 tagtcatcct tgtgttaatg acaggcagtg gctgggatct gtagagggtg ggaaggagga
     2941 ccatcacaag acctagggag aggaagtccc caaaatgctt gggacatgac ccatcctgag
     3001 gccagataca tactttaaaa ttcagatatt caccgtagca ggtagacaga tggaggatgg
     3061 ctggggaagg gagttgtggg ctgaagttta ggggactgca gacacatctg ggcccagtcc
     3121 tcagctgttc cttgctggta tacctcagaa gtggaatgtc agagtgggct actagagacc
     3181 tctgacccca gcagcactgg cttgccctca tatgtggggt gtagtcacgt cagtgacttc
     3241 ctgggaattg cttgtttcag atcatattga tctctttcct tttgtctctc accgtatggt
     3301 atgacttgaa tcagttttga ttctatgtgt aagttctcat cgtttggaac ctggtatttc
     3361 tgttgtgttc ttggcagtgc ataggaaccc agcctcctgt gttttgaccc tcctgcaggc
     3421 actgtgggac tcgagggcag cagatccatc tcccgtccct tgctgcatga tggtcactag
     3481 ctgatctgtg atggcgtccc ttcccccatt gattttctgt gtttgaagta tgtgcatatg
     3541 tgctttacag aataaaacat ctggatttac ttggtttgcc gttttaattc cagccggatt
     3601 ggtgttcttt aaacaaaaag taggcaggga gcacttccag ggctttgcag gctgtttttg
     3661 ttttttttt
//
