LOCUS       NM_001289666            3206 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 241 (Tmem241), transcript
            variant 1, mRNA.
ACCESSION   NM_001289666 XM_006526061
VERSION     NM_001289666.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3206)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3206)
  AUTHORS   Zhao,N., Deng,G., Yuan,P.X., Zhang,Y.F., Jiang,L.Y., Zhao,X. and
            Song,B.L.
  TITLE     TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P
            modification of NPC2 and cholesterol transport
  JOURNAL   J Lipid Res 64 (12), 100465 (2023)
   PUBMED   37890669
  REMARK    GeneRIF: TMEM241 is a UDP-N-acetylglucosamine transporter required
            for M6P modification of NPC2 and cholesterol transport.
REFERENCE   3  (bases 1 to 3206)
  AUTHORS   Liu,N., He,J., Fan,D., Gu,Y., Wang,J., Li,H., Zhu,X., Du,Y.,
            Tian,Y., Liu,B. and Fan,Z.
  TITLE     Circular RNA circTmem241 drives group III innate lymphoid cell
            differentiation via initiation of Elk3 transcription
  JOURNAL   Nat Commun 13 (1), 4711 (2022)
   PUBMED   35953472
  REMARK    GeneRIF: Circular RNA circTmem241 drives group III innate lymphoid
            cell differentiation via initiation of Elk3 transcription.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3206)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK051727.1 and AK038472.1.
            
            On Jan 25, 2014 this sequence version replaced XM_006526061.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK038472.1, BC137621.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                AK051727.1         2-98
            98-3206             AK038472.1         43-3151
FEATURES             Location/Qualifiers
     source          1..3206
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 5.98 cM"
     gene            1..3206
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /note="transmembrane protein 241"
                     /db_xref="GeneID:338363"
                     /db_xref="MGI:MGI:2442435"
     exon            1..157
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            158..204
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            205..282
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            283..364
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            365..442
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            443..468
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            469..520
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            521..569
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            570..615
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            616..651
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            652..686
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            687..756
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            757..850
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            851..915
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            916..3206
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2571
                     /gene="Tmem241"
                     /gene_synonym="6030446N20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcagagcgtc gtgtcagggc ggcggagacc gaggtggctg gctgggctct gcagcctgtc
       61 cccgggaagc cgggagagct gacagatgaa cgtgaggcgg tccctgctcg gcctcacctt
      121 ctgcacctgt tacctggctt ctcacctcac caacaagtat gtcctgtctg tcctgaaatt
      181 tacctaccct acattattcc aagggtggca gacattcatt ggtggacttt tgcttcatat
      241 gtcatggaaa ctaggatggg tggagctcca cagcagtcca agatctgatg ttttgatatg
      301 gcttcctgct tcagcgctgt ttgtgggcat aatctatgcg gggtccaaag ctttgtctag
      361 actggctgtt cctgtgtttt tcattttgca taatgtagct gaagttctca cctgtgggta
      421 ccagaagtgt gtctggaaag agaaaacatc gctctcaaag atctgtagtg ccctcttcct
      481 cttggctgct gcagggtgcc ttcccttcca agactctcag tttgatccag atggatattt
      541 ttgggctctt atccacatct tttgtgtagg ttcttacaaa atacttcgga agtcccggaa
      601 gcccactgtg ctaagtgaca ttgaccagca gtacttaaac tatatattca gcatggtact
      661 cctggcattt gcatctcatc cgacaggtga cctcttcggt gccctggact ttccattctt
      721 gtatttctac aggttccatg gcagctgctg tgccagtgga gttttgggat tcttcctcat
      781 gctcagtaca gtcaggctga gaagcatcct ggccccaggg cagtgcgcag cctggatcct
      841 ctgtgctaag gtcgtcacag ctggcttgtc gatgttgctg tttgatatgg ccctgaccaa
      901 agcaactgtg ggatgcttcc tgcttggtgg acttggcgag gccctgctgg ttttctcaga
      961 gcggaggagt tcctcatgaa gatggacaag aaaaggcagc ctgcagcttg ctgctggagg
     1021 acacagcccc tggcctccct cttgagagct ataaaaagac cacattacag tgagaccatg
     1081 ctgaggtttc cagctgggca aagctgtgag ctgcacatgc cccagccaag ttgaacacat
     1141 ggatggctga tgattgcaac agcccacttt cttattatta gggggacttc ccagggaccg
     1201 ctgcagagaa tgggtccgtc ttatatgctg aaccatctcc tctctgctgc acccagttct
     1261 gcgggatcaa gaagcagagg gtcttaatgg gatggctgtg tcctaccagt tactgctttg
     1321 gaattgatgt cacagtccat ggaatcttgt tgcattttgg ggagttgttt tgtgtcttta
     1381 catcttggag tctcttatac cctttgattt ttctggagcc catgccttcc cacacaaaac
     1441 aagacatgta tgttatgaca tgtgggacag ggcaggtgtg gggttgatca ggggcgctgg
     1501 accaagtgaa accccagcga agatccttag cttggagtga gtggcagcct ttgtggttat
     1561 gctgatgtag ttccagcctc taattttctc ttgttctttt gagtttgtca ggatgtgttg
     1621 aatctgtaga ccattgaaca tgggtagatt aagctgataa ctaatcgatt acctgaagtc
     1681 tttgaagtat tctgtagttc aggtgggcct taaataccac accttctgcc ttagcctcct
     1741 gagtgctgag atcgcaggca ctagctattt tatgcttagt gtgtgttccc taaagtcttt
     1801 actatgtgtg attccttcat aactcagaag agatctcaag tcattgagca ctggatttta
     1861 tctcttacac caaattataa aaattaaagt cccatagctc tagagaataa accactatat
     1921 aaaatattca cttgattctg aagccagcaa ggcttaagaa aataatgcta gattttcttc
     1981 tcattggtgt cacagaactt ggttgttgtt ccaagtcttc ggtggttttg gccgtactga
     2041 gcttacttca tcagccttcc agtgtaggag acccgtgcca ttgacccaca gagaccctct
     2101 gggctatgag gattgctcct tgttgcaggc tcagatccag gatgaatgag agcagctcat
     2161 tgttgctaca ttttttcccc aacttgttgg caaacagaat gaaacaggag gatagattta
     2221 tgtatataga atgtgaggac ctttaattcc tgtcctttcc tgatctctgc tcatcattta
     2281 aggtgaaaat gttccaagac ttgatgcctg tgtacttttc aatttgctgt cttagaatat
     2341 ttttacattt atttattcta ttattttatg tgtattgtat accacatgtg tgcctggtac
     2401 ctgtgaaggt cagaagaggc catcagctct acagaaactg gagttacaga tagtgagctg
     2461 ccacgtgact gctgtgaatt gaactcatgc tctgcaaaag tgatcttaac tgctgagcta
     2521 actcgactct cctgccctgt aatttgcttt ttaaaaatat ttgtatttaa attgtctgta
     2581 tgtttataag catgtgcata atgagtgcag gtgccccagg gaggccagag gagaatattg
     2641 ggtcccctgg agttggaatt acaggaagtt atgagctgcc cagtgtgggt tctgggagac
     2701 aaactctggt cctctatagg aacattgcat ggtcttaact gagcgtgtct ctctagctga
     2761 gcactcgctg ttgttcttca tctagtatag caaaccagta agtagatagg aatgtcctat
     2821 agagcaaata gagactctga gcttagaatt ttcctttttt ttaataccca caaaactttc
     2881 tactgctccc tttcccctga ccccactttt gcaaaagtgg tatctgtcca gatgtcatcc
     2941 tgtgcctgtc ctaaatgtca tttaagcaat ggagagtcct caggtggaga gaaccacaca
     3001 gctactaatc ccagcgccat ctctagcagg aagaaccttt actgagaagt tttactgaga
     3061 agtttcagac actttggctg taaagatgtc tagcagctag tgctttgttt ttcaaccaca
     3121 ttgagttcca ttgttcctga gtctctctcg ggtgtttttg ttgtgtgctg agaaggtaag
     3181 atgatgggac cagttgctcc ttcagt
//
