LOCUS       NP_001094976             173 aa            linear   ROD 30-APR-2024
DEFINITION  transmembrane protein 240 [Mus musculus].
ACCESSION   NP_001094976 XP_001474851 XP_358624
VERSION     NP_001094976.1
DBSOURCE    REFSEQ: accession NM_001101506.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 173)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 173)
  AUTHORS   Khang,R., Jo,A., Kang,H., Kim,H., Kwag,E., Lee,J.Y., Koo,O.,
            Park,J., Kim,H.K., Jo,D.G., Hwang,I., Ahn,J.Y., Lee,Y., Choi,J.Y.,
            Lee,Y.S. and Shin,J.H.
  TITLE     Loss of zinc-finger protein 212 leads to Purkinje cell death and
            locomotive abnormalities with phospholipase D3 downregulation
  JOURNAL   Sci Rep 11 (1), 22745 (2021)
   PUBMED   34815492
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 173)
  AUTHORS   Hu,Q., Wang,G., Chen,X., Zhang,L., Zhao,W., Jiang,Y., Zhang,C.,
            Sun,J., Xu,H., Li,H., Kong,Q., Zhao,J., Li,X., Zhang,X., Lv,W.,
            Liu,Y., Yang,G., Mu,L. and Wang,J.
  TITLE     Neural-specific distribution of transmembrane protein TMEM240 and
            formation of TMEM240-Body
  JOURNAL   Int J Biol Macromol 161, 692-703 (2020)
   PUBMED   32535204
  REMARK    GeneRIF: Neural-specific distribution of transmembrane protein
            TMEM240 and formation of TMEM240-Body.
REFERENCE   4  (residues 1 to 173)
  AUTHORS   Homa,M., Loyens,A., Eddarkaoui,S., Faivre,E., Deramecourt,V.,
            Maurage,C.A., Buee,L., Huin,V. and Sablonniere,B.
  TITLE     The TMEM240 Protein, Mutated in SCA21, Is Expressed in Purkinje
            Cells and Synaptic Terminals
  JOURNAL   Cerebellum 19 (3), 358-369 (2020)
   PUBMED   32002801
REFERENCE   5  (residues 1 to 173)
  AUTHORS   Trinidad,J.C., Barkan,D.T., Gulledge,B.F., Thalhammer,A., Sali,A.,
            Schoepfer,R. and Burlingame,A.L.
  TITLE     Global identification and characterization of both O-GlcNAcylation
            and phosphorylation at the murine synapse
  JOURNAL   Mol Cell Proteomics 11 (8), 215-229 (2012)
   PUBMED   22645316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ116478.1, BY725301.1, AU255417.2, AL670236.9 and CJ257322.1.
            
            On or before Feb 23, 2008 this sequence version replaced
            XP_001474851.1, XP_358624.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY725301.1, ERR3363658.2412460.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..173
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 87.18 cM"
     Protein         1..173
                     /product="transmembrane protein 240"
                     /calculated_mol_wt=19874
     Region          1..173
                     /region_name="TMEM240"
                     /note="TMEM240 family; pfam15207"
                     /db_xref="CDD:405814"
     Site            5..25
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (B2RWJ3.1)"
     Site            90..110
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (B2RWJ3.1)"
     Site            169
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000269|PubMed:22645316; propagated from
                     UniProtKB/Swiss-Prot (B2RWJ3.1)"
     CDS             1..173
                     /gene="Tmem240"
                     /gene_synonym="EG381582; Gm5151"
                     /coded_by="NM_001101506.1:287..808"
                     /db_xref="CCDS:CCDS51403.1"
                     /db_xref="GeneID:381582"
                     /db_xref="MGI:MGI:3648074"
ORIGIN      
        1 msmsantmif milgasivma iaclmdmnal ldrfhnyilp hlrgedrvch cncgrhhihy
       61 vipydgdqsv vdasenyfvt dnvtkqeidl mlglllgfci swflvwmdgv lhcavrawra
      121 grrydgswtw lpklcslrel grrphrpfee ptgnmvhvkq klyhnghpsp rhl
//
