LOCUS       NM_001101546            2507 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus transmembrane protein 233 (Tmem233), mRNA.
ACCESSION   NM_001101546 XM_620250 XM_913991
VERSION     NM_001101546.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2507)
  AUTHORS   Jami,S., Deuis,J.R., Klasfauseweh,T., Cheng,X., Kurdyukov,S.,
            Chung,F., Okorokov,A.L., Li,S., Zhang,J., Cristofori-Armstrong,B.,
            Israel,M.R., Ju,R.J., Robinson,S.D., Zhao,P., Ragnarsson,L.,
            Andersson,A., Tran,P., Schendel,V., McMahon,K.L., Tran,H.N.T.,
            Chin,Y.K., Zhu,Y., Liu,J., Crawford,T., Purushothamvasan,S.,
            Habib,A.M., Andersson,D.A., Rash,L.D., Wood,J.N., Zhao,J.,
            Stehbens,S.J., Mobli,M., Leffler,A., Jiang,D., Cox,J.J.,
            Waxman,S.G., Dib-Hajj,S.D., Neely,G.G., Durek,T. and Vetter,I.
  TITLE     Pain-causing stinging nettle toxins target TMEM233 to modulate
            NaV1.7 function
  JOURNAL   Nat Commun 14 (1), 2442 (2023)
   PUBMED   37117223
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2507)
  AUTHORS   Santana-Varela,S., Bogdanov,Y.D., Gossage,S.J., Okorokov,A.L.,
            Li,S., de Clauser,L., Alves-Simoes,M., Sexton,J.E., Iseppon,F.,
            Luiz,A.P., Zhao,J., Wood,J.N. and Cox,J.J.
  TITLE     Tools for analysis and conditional deletion of subsets of sensory
            neurons
  JOURNAL   Wellcome Open Res 6, 250 (2021)
   PUBMED   35233469
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2507)
  AUTHORS   Nakano,Y., Jahan,I., Bonde,G., Sun,X., Hildebrand,M.S.,
            Engelhardt,J.F., Smith,R.J., Cornell,R.A., Fritzsch,B. and Banfi,B.
  TITLE     A mutation in the Srrm4 gene causes alternative splicing defects
            and deafness in the Bronx waltzer mouse
  JOURNAL   PLoS Genet 8 (10), e1002966 (2012)
   PUBMED   23055939
REFERENCE   4  (bases 1 to 2507)
  AUTHORS   Sallman Almen,M., Bringeland,N., Fredriksson,R. and Schioth,H.B.
  TITLE     The dispanins: a novel gene family of ancient origin that contains
            14 human members
  JOURNAL   PLoS One 7 (2), e31961 (2012)
   PUBMED   22363774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115795.11.
            
            On Jun 9, 2022 this sequence version replaced NM_001101546.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BB629300.1, SRR12282455.659277.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-346               AC115795.11        162068-162413       c
            347-483             AC115795.11        130464-130600       c
            484-2507            AC115795.11        117894-119917       c
FEATURES             Location/Qualifiers
     source          1..2507
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 56.1 cM"
     gene            1..2507
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /note="transmembrane protein 233"
                     /db_xref="GeneID:545798"
                     /db_xref="MGI:MGI:3651514"
     exon            1..346
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..490
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /note="dispanin subfamily B member 2"
                     /codon_start=1
                     /product="transmembrane protein 233"
                     /protein_id="NP_001095016.3"
                     /db_xref="CCDS:CCDS51629.1"
                     /db_xref="GeneID:545798"
                     /db_xref="MGI:MGI:3651514"
                     /translation="MSRQPEPQAARTVRSSSLPVSPTSPMSQYASRSDSKGALDSSSP
                     EAYTEDDKTEEDIPAPSNYLWLTIISCFCPAYPVNIVALVFSIMSLNSYNDGDYEGAR
                     RLGRNAKWVAIASIIIGLVIIGVSCAVHFSRNP"
     exon            347..483
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /inference="alignment:Splign:2.1.0"
     exon            484..2507
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2475..2480
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /note="hexamer: AATAAA"
     polyA_site      2507
                     /gene="Tmem233"
                     /gene_synonym="DSPB2; Gm13843"
                     /note="major polyA site"
ORIGIN      
        1 agaggactga cctacgcagg agtagtgaag tctcatctcc cttgagcccg gagcagaaag
       61 cttttcagag cctctgcaag ccatgagtcg acagccagag ccccaggctg cacgaaccgt
      121 gcgctcctca tccctcccgg tgtcaccgac ttcgcccatg tctcagtatg cttcccgctc
      181 agactcaaaa ggagctttgg acagcagcag cccggaagcc tatacagaag atgacaagac
      241 cgaggaggac atacctgccc ccagtaacta tctatggctc accattatct cgtgtttctg
      301 cccagcgtac ccggtcaaca tcgtggcttt ggtcttctcc atcatgtctc tgaacagcta
      361 caatgatgga gactacgaag gagccaggag gctggggcgg aacgccaagt gggtggccat
      421 tgcctccatc atcatcggcc tggtcatcat cggcgtctcc tgtgcggtgc acttctccag
      481 gaacccctga ggaacagctc tcagctggga agcatggcgg acggtcctca tctgcacaca
      541 ctcccaaaga agtttctgag gaatggatcc ttgattttaa aactgtaaga tcttttcctc
      601 caggactctc cagaggcggg tccctggcaa atgaacaccc actagtcggg aatgtacgga
      661 gctcagctgc agtgcagaca cacccaccaa agccactggc agatgaaaaa atgaaaatga
      721 aaaatggcgt ctccatgtct cagctcagca aaacctttgc atccattcct cctcttcagg
      781 aatgaacttc agaaacctcg ctgcttctcg ggacgtctgg atttgggggc ggcgaggggc
      841 gcaggtggct ttcagggaga gctgtgaatg ctggtgttta caaaaacaag tacaaatacc
      901 atagcatgct taaagttctc gagaacagtt gaggtcatag acttatttct tcttcccttt
      961 ctccgtgtgg tagggtctcc ccacctccct cagcgtcccc agagtccacc cagacttcct
     1021 aggtttttgt cccagtttta atttccccac cgccttctct tgcttgtatc tgcattgatc
     1081 atttggagcc ggagaaggaa ccagatccta ggcatctgta taccctctcc accccgcgtg
     1141 tggagtaaaa atggccattt tacgtaatgt ggctttcttt tctatctatt tctttcagca
     1201 aatctcaggc aagagctttg atttttccag gaagccaccc taaagagtca tacccttgtg
     1261 cttcttcccc gcccctaccc ccgcccccgc ccccgcccct tgtataaagt caacagttta
     1321 agttcaggat gctgttgtcc cgcccaccag aggatgctgg cttagagttt ttttgcagtg
     1381 tgcaaagcac gtgccaccgg tggtactcaa ggcgatttct gatttaaaaa aaaaaaaaaa
     1441 tgatggtaaa tagcgctgaa tttcgaagaa ggcttcctgc tttatccttt ctcagtcttt
     1501 gctgctgcaa ggagaatgtc tctcttgggt accagtgggt ccttcacacc ttcccacaac
     1561 accagtcatt gcccaccgta gcaaagagac agtggccttc aggtccagtc ttggtctcca
     1621 tagacctcag tgacattgtt tcgttcttat agtatttgtt tataggcttc tgcacagaca
     1681 gacagacaga cagaagctct gtatcattta agcaagtaaa ttcagagaga gatttaaagt
     1741 gattatggtt aacaggtgat atttatggcc aaataaaatc tccaaaacta atgtcagaaa
     1801 cacagcgaca cgaacttgaa tagaaaagag gcatcccgtt ttattgaatg agcaagtgat
     1861 caagagtcaa aacacctgtc tcaatgcctt tggggagggg gggatctcag gcaacccagg
     1921 ctggccttga attgctatgt aaccagggat ggccttcttc tgcctctgcc tttccagtgc
     1981 tgaggtcaca ggcttctgct gcctctccca gaccctgcat ttacttccat gagattagct
     2041 acgagagttg attttagaca agtttcttct gaaaaaaatg gagataaaag ctgctacctc
     2101 cttacctcat actgttatga aaattaattg ctatcatgaa tgtgcccctg aggcggggag
     2161 actctgtgca ctaaacaaat atgaagcaca ttgatagtgg attgaaggtg tttgggaaaa
     2221 cactgggtcc tggggcgggg ggcttggtgg cgagggggga gggaggttgg tgggcacagg
     2281 actccaccca ggtatgtcat gagaaaaccc ttgtcccaga aggagactga cttagggaca
     2341 ggaattctca gcatacaggg atgccaccac cattccagca tattggatcc tgattcttat
     2401 atcctgtttg tgtgtttcag tccctggtct ttccccaaat caaatggaaa ggaagtgttg
     2461 ttgagagaga acggaataaa aacggcttta agtaagccca tttgcca
//
