LOCUS       NM_025667               1497 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 222 (Tmem222), transcript
            variant 1, mRNA.
ACCESSION   NM_025667 XM_912290
VERSION     NM_025667.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1497)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1497)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK160188.1, AK079189.1 and AI847863.1.
            
            On May 23, 2007 this sequence version replaced NM_025667.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the supported protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160188.1, AK017503.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AK160188.1         2-26
            26-1480             AK079189.1         14-1468
            1481-1497           AI847863.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 66.25 cM"
     gene            1..1497
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /note="transmembrane protein 222"
                     /db_xref="GeneID:52174"
                     /db_xref="MGI:MGI:1098568"
     exon            1..260
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..693
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /codon_start=1
                     /product="transmembrane protein 222"
                     /protein_id="NP_079943.2"
                     /db_xref="CCDS:CCDS51321.1"
                     /db_xref="GeneID:52174"
                     /db_xref="MGI:MGI:1098568"
                     /translation="MAEAEGSSPLLLQPPPPPPRMAEVETPTGAETDMKQYHGSGGVV
                     MDVERSRFPYCVVWTPIPVLTWFFPIIGHMGICTSAGVIRDFAGPYFVSEDNMAFGKP
                     AKFWKLDPGQVYASGPNAWDTAVHDASEEYKHRMHNLCCDNCHSHVALALNLMRYNNS
                     TNWNMVTLCCFCLIYGKYVSVGAFVKTWLPFVLLLGIILTVSLVFNLR"
     exon            261..345
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     exon            346..377
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     exon            378..474
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     exon            475..605
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     exon            606..1482
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1464..1469
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /note="hexamer: AATAAA"
     polyA_site      1482
                     /gene="Tmem222"
                     /gene_synonym="5730406H10Rik; D4Ertd196e"
                     /note="major polyA site"
ORIGIN      
        1 cccggaagtg atgacacagg ggcgagcggc ggcgcggtcg gccttcccga gcgggacgcg
       61 cgcgggatgg cggaagcgga agggagttct ccgcttctgt tacagccgcc gccgccccct
      121 cctcggatgg cggaagtaga aacgccgacg ggggccgaga cggacatgaa gcagtaccac
      181 gggtccggtg gcgttgtcat ggacgtggag cggagccgct tcccctactg cgtggtgtgg
      241 acacccatcc cggtgctcac gtggtttttc cccatcattg gccacatggg catctgcaca
      301 tctgcagggg tcattcgtga cttcgctggc ccctattttg tttcggaaga caacatggcc
      361 ttcggaaagc ctgccaagtt ctggaaattg gaccccggac aggtgtatgc gagtgggccc
      421 aatgcatggg acacggctgt gcacgatgcc tccgaagagt ataagcaccg aatgcacaat
      481 ctctgctgtg acaactgcca ctcccacgtg gctttagccc tgaacctgat gcgttacaac
      541 aacagcacca actggaacat ggtgacgctc tgctgcttct gcctcattta tgggaagtat
      601 gtcagtgttg gagcctttgt gaagacctgg ctgccctttg tccttctcct cggcattatc
      661 ctgaccgtca gtctcgtctt caatctgcgg tgatagcttt cagatggtct aagcctcaag
      721 gaggctcctg acactcaccc cttttggtcc caattctttt attccccacc cctcaggcag
      781 tgttgcctcc tgggttgaag tagggtcagg acttgggaca gaagtgccga tactgagcac
      841 ctgatgaggt cacttagagc ctccttgtcc tttctccctg ggcctgagac ctcacccttg
      901 tggcattccc agtgccatcc tgggaaggcc ttccttccct tagagcattt cctgccacca
      961 tcactgggct actcttccca tgcccagggc acagtgagga caagaaccca cgggcaaagc
     1021 agtgttcaga gctggatttg aagctgtttg ctggctggtg gttgtgtccc aaagtagggc
     1081 atgtgttatg agaagtgctg cacgccaaga gacttggaac cttctctgct ggcctcgaat
     1141 ggaccgggag ggctggctat gttctttctg ccacaccagc acagtgtgtg cctcatcacc
     1201 gctaatgtgg gccctggcta gcaagggctg agggcactta cgtgcagagt gggtcctctg
     1261 taaattaggt aacgtgaatc ccacttgttt ccagcccagg aggcctcgtg ctggggatag
     1321 aaccctttag gtccaaaatg tgaataactt gtcagagcag ctggtacccc tgatcggctg
     1381 ggtctgcttc cggttgctac aatgggccct atgcagcctc cccctggtct gcaggctcct
     1441 ttataagggg ctccctggca ggaaataaag ttttaagtct aaaaaaaaaa aaaaaaa
//
