LOCUS       NM_001291042            1597 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus transmembrane protein 220 (Tmem220), transcript
            variant 2, mRNA.
ACCESSION   NM_001291042 XM_006533587
VERSION     NM_001291042.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK043094.1 and AK078505.1.
            
            On Mar 22, 2014 this sequence version replaced XM_006533587.1.
            
            Transcript Variant: This variant (2) lacks an in-frame exon in the
            central coding region, compared to variant 1. The encoded isoform
            (2) is shorter, compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078505.1, SRR1660819.374405.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AK043094.1         2-4
            4-1597              AK078505.1         3-1596
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 40.59 cM"
     gene            1..1597
                     /gene="Tmem220"
                     /note="transmembrane protein 220"
                     /db_xref="GeneID:338369"
                     /db_xref="MGI:MGI:2443691"
     exon            1..118
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..529
                     /gene="Tmem220"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="transmembrane protein 220 isoform 2"
                     /protein_id="NP_001277971.1"
                     /db_xref="CCDS:CCDS70209.1"
                     /db_xref="GeneID:338369"
                     /db_xref="MGI:MGI:2443691"
                     /translation="MAPAVATWAPGLWRACNALMAAFFALAAVVQVNDPDAELWVVVY
                     MIPAVLTLLVGFNPLVTGNFIWKSVSAIHMLFCALWAGGLAYHFLLHAKQNLLNEEEG
                     RELSGLVIVTAWMALCHSSSKNPGGGRMHLAIAVVITLLPLLSWVYVHMNKEMRSSWP
                     THCKTVI"
     exon            119..148
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
     exon            149..209
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
     exon            210..333
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
     exon            334..393
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
     exon            394..1597
                     /gene="Tmem220"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcctgctcc tccggcttcc aggtcatggc gccagcagtg gctacttggg ctcccggctt
       61 gtggcgggcc tgcaacgcac tcatggcagc tttcttcgcc ctggccgctg tggtgcaggt
      121 aaacgatcca gatgcagagt tgtgggtggt ggtgtacatg atcccagcag tgcttaccct
      181 gcttgttggg tttaatcctc ttgtcacagg caacttcatc tggaagagtg tgtctgcgat
      241 acacatgctg ttctgtgcgc tgtgggctgg cggcttggcg taccacttct tgcttcacgc
      301 aaagcagaac ctcctaaatg aggaagaagg cagggagctg tctggcctgg tgattgtcac
      361 agcatggatg gccctgtgcc acagctcatc caagaatcca ggtggtggaa gaatgcactt
      421 ggctattgct gttgtaatca ccctactccc actcctgtcg tgggtctacg tacacatgaa
      481 caaggagatg cggtcctcct ggccaactca ctgcaagaca gtcatttaaa tgaacccaat
      541 aatgtttaca acatgttata cacattgggg taatgggacg atttcccaga gatgatttaa
      601 agtcttggga atgtaacaag gctactcaca atgtgatgga agattgacta ggtcagataa
      661 gaattgggag ctgagtctcc agaggtctct tctgcaacag cactggacca ggcaatgagc
      721 agaaacttga gtttgaatcc agctttagca ctatgtgatg gggcaaaccc acgaatctcc
      781 tggtacatat ttcctcacat ataaagtagg atgtcagatc tcattagtta ccacaaccaa
      841 actattgttg aaggcactct gagaagatga agctcacttg agttccaaag ggagtaagag
      901 tgagaggggg ctgaggctat aaccagcctc atgctgacat ggagggaggt tcaaaaacta
      961 atcttaatgt acttaactgg ctcagctgta ctgaacccag aaaaattcca gggcaggtga
     1021 accaaatgaa agtagaaatt aaagaaaata tagaaaagat aaatttggag ttagcaagaa
     1081 tagggaatat taatcataag ttattctccg tgaaaactaa gatggaaatc tatacatctt
     1141 tttaatgaat gttgaagtga ccacagggga ggagagctct gtagggtgac acagtccaac
     1201 agggcataca caggttgtta tcgagcactt gacctgtggg cagagcactt gacctgtggg
     1261 cagggtgacc aaagaagtca atttttaact tttctacttt tagaagcagg gagtcaactg
     1321 ccaggaaaag ttaagtgtgc atgggatcgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     1381 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtatggatct tcttcaactg
     1441 caaattttgg tatggactgt tggtgttggt ctggcgctat gtattcaaat gctaaatact
     1501 ggcccctgag atctgattgc ctcatttcat gtacagcaaa tattatgtaa actttgcttg
     1561 ccaatctttt gtgactggtt aaataaaagt ggttaac
//
