LOCUS       NP_653108                687 aa            linear   ROD 08-JUN-2024
DEFINITION  transmembrane protein 214 [Mus musculus].
ACCESSION   NP_653108
VERSION     NP_653108.2
DBSOURCE    REFSEQ: accession NM_144525.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 687)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 687)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109606.11 and AK034883.1.
            
            On Jun 10, 2003 this sequence version replaced NP_653108.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143078.1, BC029150.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 16.9 cM"
     Protein         1..687
                     /product="transmembrane protein 214"
                     /calculated_mol_wt=76299
     Region          1..38
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BM55.1)"
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q6NUQ4; propagated from
                     UniProtKB/Swiss-Prot (Q8BM55.1)"
     Region          8..681
                     /region_name="TMEM214"
                     /note="C-terminal, caspase 4 activator; pfam10151"
                     /db_xref="CDD:462966"
     Region          70..108
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BM55.1)"
     Site            269
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8BM55.1)"
     Site            307
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8BM55.1)"
     Site            481..501
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BM55.1)"
     Site            614..634
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BM55.1)"
     CDS             1..687
                     /gene="Tmem214"
                     /gene_synonym="1110039B18Rik; 4921530J21Rik"
                     /coded_by="NM_144525.4:90..2153"
                     /db_xref="CCDS:CCDS19164.1"
                     /db_xref="GeneID:68796"
                     /db_xref="MGI:MGI:1916046"
ORIGIN      
        1 maarsagsgg wevvkrgrrp gassggrggg ggsdrralge angvlkydls spiqttstly
       61 ergfekimkr qnkeqvpppa aeskkpinkk qpkkvtavps qnqkqgpfrr ledalkaldv
      121 aalqkeldks qsvftgnpsv wlkdlasyln yklqtprmep tlsqyphdyp yslvsrelrg
      181 iirglltkaa gsvelffdhc lftmlqeldk tpgeslhgyr iciqavlqdk pkivtsnldk
      241 flellrshqs rpakcltimw algqagftnl teglkvwlgi mlpvlgikal spfaiayldr
      301 lllmhpnltk gfgmigpkdf fplldfaymp nnslspslqe qlcqlfprlk vlafgakpes
      361 slhtyfpsfl sratpscpaa mkkellaslt qcltvdplst svwrqlypkh lsqssllleh
      421 llkswehipk karkslqeti qslkvtnqel lkkgsggseh vltcdtackg llqrargprp
      481 pwarlfllll vfavgflchd lrsnsslqas ltgrllrssg llpvgqqvca rlssyslqsy
      541 nwlqetlpac gshllavvqp slqlawthiy aifsflsahc asylacfsds lagffqrvql
      601 pealqqlfha lkellllfch svllptwhll laalaqvqeh cheacrgdvt wdciktqlsr
      661 aaqwtwlclq dvtvafldwa ltmisqq
//
