LOCUS       NM_178625               3499 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 209 (Tmem209), transcript
            variant 1, mRNA.
ACCESSION   NM_178625
VERSION     NM_178625.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3499)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3499)
  AUTHORS   Yao,F., Huang,S., Liu,J., Tan,C., Xu,M., Wang,D., Huang,M., Zhu,Y.,
            Huang,X. and He,S.
  TITLE     Deletion of ARGLU1 causes global defects in alternative splicing in
            vivo and mouse cortical malformations primarily via apoptosis
  JOURNAL   Cell Death Dis 14 (8), 543 (2023)
   PUBMED   37612280
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3499)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY780525.1 and BC057109.1.
            
            On Jul 24, 2015 this sequence version replaced NM_178625.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057109.1, AK044877.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                BY780525.1         3-79
            78-3499             BC057109.1         1-3422
FEATURES             Location/Qualifiers
     source          1..3499
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.52 cM"
     gene            1..3499
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="transmembrane protein 209"
                     /db_xref="GeneID:72649"
                     /db_xref="MGI:MGI:1919899"
     exon            1..99
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1782
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 209 isoform 1"
                     /protein_id="NP_848740.3"
                     /db_xref="CCDS:CCDS19972.1"
                     /db_xref="GeneID:72649"
                     /db_xref="MGI:MGI:1919899"
                     /translation="MMQGDVSPNPSLIDRTIKMRKETETRKVVLAWGLLNVSMAGMIY
                     TEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQ
                     ALLGLKQAVVQTTPPRDLAATQISPSPPSPSIQGQSVLSYSPSRSPSTSPKFATSCMT
                     GYSPQLQGLSSGGLGSYSPGVTYSPVSGYNKLASFSLSPSSPYPTTVGPVESSGLRAR
                     YRSPPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSTSPTFWNYS
                     RSVGDYAQTLKKFQYQLACRSQAPCANKDEADLISKQAAEEVWARVTMNRQLLDHMDS
                     WTAKFRNWISETILVPLVQEIESVSTQMRRMGCPELQIGEASVTSLKQAALVRAPLIP
                     TLNAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAII
                     MHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAVNPPHYEL
                     IYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE"
     exon            100..236
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            237..295
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            296..427
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            428..669
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            670..871
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            872..1047
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1119
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1216
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1342
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1440
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1555
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1653
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1727
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..3480
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2278..2283
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2298
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
     regulatory      2326..2331
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2350
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
     regulatory      3462..3467
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3480
                     /gene="Tmem209"
                     /gene_synonym="2700094F01Rik"
                     /note="major polyA site"
ORIGIN      
        1 actgtagccc ggcttgcccg ccgccgccgc cttagtcttg cctctgcgca tgtgcagtag
       61 ggagtggcgc gagtccacgg cttcctgctg aagaacatga tgcaaggaga cgtaagcccc
      121 aatccttccc ttattgacag aaccatcaag atgagaaaag aaacagaaac taggaaagtg
      181 gttttagctt ggggactcct aaatgtatcc atggctggaa tgatatatac tgaaatgact
      241 ggaaagttaa tcagtacata ttataatgtg acatactggc ccctctggta tatcgaactc
      301 gcacttgcat cgctcttcag tcttaatgcc ttgtttgatt tttggagata cttcaaatat
      361 accgtagcac caacaagtct ggtagttagc cccggacagc aagcactgtt agggttgaaa
      421 caggctgttg tgcagactac acctccccgt gatttggcag caacccaaat ctctccatct
      481 ccaccttccc cttcgattca aggtcaaagt gtgttaagtt atagcccatc tcgttcaccc
      541 agtaccagtc ccaagtttgc caccagctgt atgactgggt atagccctca actgcaaggc
      601 ctgtcgtcag gaggccttgg ctcttacagc cctggtgtga cttactcgcc tgtcagtggc
      661 tacaataagt tggccagctt tagtctgtct ccttcttctc cataccctac cactgtgggc
      721 ccagtggaga gcagtggatt gagagctcgc taccgttctc cacccacggt ctacaactca
      781 cccactgaca aagaggacta catgacagac ctgagaactt tggacacgtt ccttagaagt
      841 gaggaagaga aacagcatag agtgaagctg gggagcccag attccacctc tccttctacc
      901 agccctacct tctggaatta cagtcgttct gtgggtgatt atgcacaaac cttaaagaag
      961 tttcagtatc agcttgcctg tagatcacag gccccatgtg ctaacaaaga tgaagccgat
     1021 ctcatttcta agcaagctgc agaagaggtc tgggcaagag tgactatgaa tagacagctt
     1081 ctcgatcaca tggattcatg gacagccaag tttagaaatt ggatcagtga gacaatattg
     1141 gtgccgcttg tgcaagagat tgagtctgtc agcacccaga tgagaaggat gggctgtcca
     1201 gagctacaaa taggagaggc gagtgttacc agcttgaagc aagctgccct ggtcagagct
     1261 cctctcattc caactctgaa tgcaattgtg cagtatttag acctcacacc aaatcaggag
     1321 tacttgtttg aaagaatcaa agaactttct caggggggct gtatgagttc attcagatgg
     1381 aacagaggtg gagacttcaa aggacgcaaa tgggatacag acctgcccac tgattctgct
     1441 atcatcatgc atgtgttttg cacctacctt gattccagat tacctccaca ccctaagtac
     1501 cctgatggaa aaacattcac ttctcagcac ttcgttcaga cgccaaataa accagatgtt
     1561 acgaatgaaa atgtgttttg tatttatcag agtgctgtca accctccaca ttatgagcta
     1621 atctatcagc ggcatgtcta caatcttcca aagggcagga ataatatgtt tcatacgttg
     1681 ctgatgttcc tttatatcat aaagaccaaa gagtcaggaa tgcttgggag agttaacctt
     1741 gggctctctg gcgtgaacat tttgtggatc tttggagagt agttcctcat ttaattccaa
     1801 acatttggac tttgctttta actggtctgg aagaagttgg agctgagccc ctccgagtgc
     1861 gcacctcttc tgacataaga tgcatgtttt gcagacttgt taaatttaac aggagacaag
     1921 ctgtgggagc ttcttgtgag catagcaaag cctgcacctt ctagtccaca gaaaagcatt
     1981 acactggatg gctctgagcg agctagtgcc gctcccttca tttggtgagg gcaaggacgc
     2041 ctctccattt taaccccagt gagaacctgc acctcatcct gtaccatcag agactgcttt
     2101 cattgttgga tagtagtgta agttctcaga tgaaccttgc tagttctctt tgttgtatct
     2161 ttatatttcc ccagtgttct acaagtcagc ctaaagctga aatgaaatta atttctaagt
     2221 gatgtagtaa ttaatcctgc tgagccatct ccccaacccc ctattgtttt ttttaatatt
     2281 aaaagagatt tgataatatt ggcatcttga aaggtcaatg cttgcattaa aattagctga
     2341 taaaattaaa cttttgggtt ttagttaaat gtctaaggac acgaaaaaaa cggttcactg
     2401 cttttattag cactgcgtgt gcgcgagggc ctgtgtgctg gcgcctgtgt atcatcagca
     2461 ggcactttat cactccttta agatcccaat gatagccttc ctgcttctag tttacaggta
     2521 gaacagagta tcagctctcc atctattctt ctatatgtgt acatagatag ggacctatac
     2581 atatctatat gtatatgaag taattagtag tcacattttt ttggtggggg ttattttcga
     2641 gacagagttt ctctgtgtag tcctggctgt cctagaactc actctgtaga ccagactggc
     2701 ctcaaactca cagagatctg cctgcctcgg cttcctgagt gctggcacca aaggtgtgca
     2761 ccaccaacgc ccggctagta gtcacatttg taatgaacat gtctttataa agattgcttc
     2821 catcacctga atgtgaacag atgggatgtg ccgtccattt ttgtatggtt tgagggtttt
     2881 tttcttcaaa aggtcagaag gttaacctta agtttaaaag ctaatgtcca caaggaagga
     2941 actgtcactt aactaactgc tcttggttac cctaaaagaa aatatcattt aaccatgcta
     3001 aacttaagga cacgttataa tttaaacctg taatttttga gagagattcg gggtgccatg
     3061 gaatcagttg ctgtgctatt taagtatcca gctgcacaga ctgcactaaa aacaccggag
     3121 aatctttaac agcacataag acaccaccaa ccctgtcttt tattataact ctgaaagaat
     3181 atagtatagt agtaaataga tgtaaaaaca cttgactatg taaaaagaaa agttgttttg
     3241 cctgcatact tagtataggt tgctgtagag ttcctataac aatgtctaca agtgtttgag
     3301 ctagctgtac ttactattat cttgtattta aacagaattg gcacagacat ggtgggaaat
     3361 tgccaggaac ctcagctgct catgaggttg aagtgggagg atcattagtt caaggccaaa
     3421 ctagggtacc ttgtgataac ctttcataaa tataagacat taataaaata attatagtaa
     3481 aaaaaaaaaa aaaaaaaaa
//
