LOCUS       NM_001253868             880 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 205 (Tmem205), transcript
            variant 3, mRNA.
ACCESSION   NM_001253868
VERSION     NM_001253868.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   2  (bases 1 to 880)
  AUTHORS   Inoue,S., Sano,H. and Ohta,M.
  TITLE     Growth suppression of Escherichia coli by induction of expression
            of mammalian genes with transmembrane or ATPase domains
  JOURNAL   Biochem Biophys Res Commun 268 (2), 553-561 (2000)
   PUBMED   10679242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY790291.1, AI573565.1 and CD775257.1.
            
            [WARNING] On Aug 6, 2024 this sequence was replaced by
            NM_001253868.2.
            
            Transcript Variant: This variant (3) uses a different splice site
            in the 5' end, which results in the use of a downstream start
            codon, compared to variant 1. The resulting protein (isoform 2) is
            shorter when it is compared to isoform 1. Variants 2-5 encode the
            same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF385916.1, BI408893.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               BY790291.1         2-190
            190-678             AI573565.1         1-489
            679-880             CD775257.1         1-202               c
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.92 cM"
     gene            1..880
                     /gene="Tmem205"
                     /note="transmembrane protein 205"
                     /db_xref="GeneID:235043"
                     /db_xref="MGI:MGI:3045495"
     exon            1..249
                     /gene="Tmem205"
                     /inference="alignment:Splign:2.1.0"
     exon            250..358
                     /gene="Tmem205"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..828
                     /gene="Tmem205"
                     /note="isoform 2 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="transmembrane protein 205 isoform 2"
                     /protein_id="NP_001240797.1"
                     /db_xref="CCDS:CCDS22913.1"
                     /db_xref="GeneID:235043"
                     /db_xref="MGI:MGI:3045495"
                     /translation="MEKGEDPGSLIKVIHLLVLSGAWGMQVWVTFISGFLLFRSLPRH
                     TFGLVQSKVFPVYFHVSLGCAFINLCILAPQRAWIHLTLWEVSQLSLLLLSLTLATIN
                     ARWLEARTTAVMRALQSIEKERGLGTEVPGNFQGPDPYRQLRDKDPKYSALRRKFYHY
                     HGLSSLCNLGCLLSNGLCLVGLALGLRSL"
     exon            359..522
                     /gene="Tmem205"
                     /inference="alignment:Splign:2.1.0"
     exon            523..863
                     /gene="Tmem205"
                     /inference="alignment:Splign:2.1.0"
     regulatory      846..851
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem205"
                     /note="hexamer: AATAAA"
     polyA_site      863
                     /gene="Tmem205"
                     /note="major polyA site"
ORIGIN      
        1 atcttcggtg agactggatg aagtccggag aggcgagatg gccagttgat tcccgcaagc
       61 caactgggca atccctaagt gggagagtcc agaggagtga gagctgtgat ctcattggct
      121 ctggctggga ggtggggcga ggcctgcggg gcggaagaaa acctgggaaa tctcaggcaa
      181 gccggagctg cactggagct gccacggttc ttggtcccta cgcctgagct cgtgtgctcc
      241 aacggtgggg gctgcagaat ggaaaaagga gaggacccgg gaagtctgat taaagtcatc
      301 cacttgctgg tcttgtctgg tgcctggggc atgcaggtgt gggtgacctt tatctcaggc
      361 ttcctgcttt ttcggagcct cccgcggcac acatttggac tggtgcagag caaggtcttc
      421 ccagtctatt ttcacgtctc cttgggctgt gccttcatca acctctgcat cttggcacca
      481 cagcgagcct ggattcacct cacactgtgg gaagtcagtc agctttccct gctgcttctg
      541 agcctcacac tggccaccat caatgctcgc tggcttgagg ctcgcaccac ggctgtcatg
      601 cgggccctgc agagcataga gaaagagcgg ggcctgggga cagaggtgcc aggcaacttc
      661 cagggccctg atccctaccg ccagctgcgg gacaaggacc ccaagtacag tgctctacgc
      721 cggaagttct accactacca tggcctgtct tccctctgca acctggggtg cctgctgagc
      781 aatgggctct gccttgtggg ccttgccctg ggactcagga gcctctaaca cagaccctgt
      841 gtgtcaataa atgcttcttt ggaaaaaaaa aaaaaaaaaa
//
