LOCUS       NM_177056               2199 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 198 (Tmem198), mRNA.
ACCESSION   NM_177056 XM_973034
VERSION     NM_177056.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ147397.1, AK038957.1, AC115011.27 and BC042776.1.
            
            [WARNING] On Aug 9, 2024 this sequence was replaced by NM_177056.5.
            
            On May 21, 2009 this sequence version replaced NM_177056.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059868.1, AK038957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                CJ147397.1         1-39
            40-1870             AK038957.1         1-1831
            1871-1871           AC115011.27        98951-98951         c
            1872-2199           BC042776.1         768-1095
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 39.15 cM"
     gene            1..2199
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /note="transmembrane protein 198"
                     /db_xref="GeneID:319998"
                     /db_xref="MGI:MGI:2443133"
     exon            1..354
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /inference="alignment:Splign:2.1.0"
     exon            355..559
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /inference="alignment:Splign:2.1.0"
     CDS             394..1476
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /codon_start=1
                     /product="transmembrane protein 198"
                     /protein_id="NP_796030.1"
                     /db_xref="CCDS:CCDS15076.1"
                     /db_xref="GeneID:319998"
                     /db_xref="MGI:MGI:2443133"
                     /translation="MPGTMETLRFQLLPPEPDDTFWGAPCEQPLERRYQALPALVCIM
                     CCLFGVVYCFFGYRCFKAVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGI
                     GLLCGLVAMLVRSVGLFLVGLLLGLLLAAAALLGSAPYYQPGSVWGPLGLLLGGGLLC
                     ALLTLRWPRPLTTLATAVTGAALIATAADYFAELLLLGRYVVERLRAAPVPPLCWRSW
                     ALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQRRRVQLMRIRQQEERKEKRRKKR
                     PPRAPPRGPRAPPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQSFRDRQTGSSLSSFM
                     ASPTDTDYEYGSRGPLTACSGPPVRV"
     exon            560..1135
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1338
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..2185
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2168..2173
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /note="hexamer: TATAAA"
     polyA_site      2185
                     /gene="Tmem198"
                     /gene_synonym="A230078I05Rik; Tmem198-1; Tmem198a"
                     /note="major polyA site"
ORIGIN      
        1 aggatggtgc accctgagtg acgtcaggag cagaggccgg agctgtccat cagcaccaaa
       61 ggccgccagc gggctcaggg catggggccg cggctccggg acagcccgag ctcctgctcc
      121 tttcccttcc ccgagccggg cgcgagtctg tggagctgca gtgccagccg gtgtcggagg
      181 tggggcgacg acgccgtcgc acagagaccc gtctctccgg cccagcagcc cccttcgcac
      241 ggcagacttt gcccggaccc cagtcagtca gagcctctgg tgtcctacaa ccccggctcc
      301 tccggcccct gcacaccctc ctttgctcgg aagctccggt cacctccggc ccaggttgtc
      361 ctgggagggt gacccccttc cattcccggc gctatgccgg gtactatgga aactctgcgg
      421 tttcagctgc tgcccccgga gccggatgac accttctggg gtgcaccttg tgaacagcct
      481 ctggagcgca ggtatcaggc actgccggcc ctcgtctgca tcatgtgctg tttgtttgga
      541 gtcgtctact gcttctttgg ttaccgctgc ttcaaggcag tactcttcct cactgggttg
      601 ctgtttggct cagtggtcat cttcctgctg tgctaccgag agcgggttct ggagacgcag
      661 ctgagtgctg gggcaagcgc gggcatcgca ctaggcatcg ggctgctctg cgggctggta
      721 gccatgctgg tacgcagtgt gggcctcttc ctggtggggc tgctgctcgg tctgctgctc
      781 gctgctgctg ccctactagg ctctgcaccc tattaccagc cgggctccgt gtggggcccg
      841 ctgggactgc tactgggagg cggcctgctc tgtgccctgc tcacgctgcg ctggccccga
      901 ccactcacca ccctggccac tgccgtgacg ggcgctgccc tcatcgccac tgccgcagac
      961 tattttgctg aactgctact gctggggcgc tacgtggtgg agcgactgcg ggctgcacct
     1021 gtgcctcccc tctgctggcg gagctgggcc ctgctggcac tctggcctct acttagcctg
     1081 atgggcgtcc tggtgcagtg gagggtgaca accgagaggg actcccacac agaagtcgtc
     1141 atcagccggc agagaaggcg agtgcagctg atgcggatcc ggcagcagga agaacgcaag
     1201 gagaagcggc ggaagaagag accccctcgg gcccctccca gaggtccccg ggcacctcca
     1261 aggcctggtc cccctgaccc tgcttataga cgcaggccag tgcccatcaa acgcttcaat
     1321 ggagatgtcc tctccccgag ttacatccag agcttccggg accggcagac tgggagctct
     1381 ctgagttcct tcatggcctc ccctacagac acggactatg agtatgggtc ccggggacca
     1441 ctgacagcct gctcgggacc ccctgtacgg gtgtagtcat gtccccattg tctggactct
     1501 gcagtcacca gctctgccac cttcgagact cctgccaggc cactactgaa gctgcaaggc
     1561 cctgtggcct ctggctgtct cgcctccttg gaaagggttg gccagccacc agaagggagg
     1621 ctgtgtctca ggttaggtag gcctggcctg agggagaagt tcccgtccaa gctcccgagg
     1681 gactcggggt gtgagcccca ctgggaagtg ctcagggttg tgtgttgccc atacatgtgt
     1741 gtgaaggggt aggcctggag gggacactgg gacccttgct ttagatttga ttggcagggc
     1801 ttcttcaggg ctagccccgc ctcctgtcct gctgctgggg tcccatgggc cactctcctg
     1861 catgtctgtg gtgggggagg cctgcctgcc tcccctattg ctctatcttc caatcattca
     1921 tctaagggtt cttgtcactg tccatggaac taatgacggc acccctcacc ctggtcccct
     1981 ggcctctgca aagccaccag ccagagggca gtggcagagg atgggggtgg gagggtgctg
     2041 tcctgggttg ggtttgggag gagggtggag ggaaaagggc ttaaatgcac ggtgcatgtc
     2101 tggtgtctgc tatgtcaccg taagacacct catgcttctg tctcctcccg ccctgtttta
     2161 catcttttat aaatgtgcca aacgaaaaaa aaaaaaaaa
//
