LOCUS       NM_030028                586 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 190 (Tmem190), mRNA.
ACCESSION   NM_030028 XM_911732 XM_973679
VERSION     NM_030028.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 586)
  AUTHORS   Nishimura,H., Gupta,S., Myles,D.G. and Primakoff,P.
  TITLE     Characterization of mouse sperm TMEM190, a small transmembrane
            protein with the trefoil domain: evidence for co-localization with
            IZUMO1 and complex formation with other sperm proteins
  JOURNAL   Reproduction 141 (4), 437-451 (2011)
   PUBMED   21273369
  REMARK    GeneRIF: A mouse sperm protein complex(es) including TMEM190 plays
            an indirect role(s) in sperm-oocyte fusion.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU936271.1, AK019807.1 and BX631095.1.
            
            On or before Jul 25, 2009 this sequence version replaced
            XM_911732.2, XM_973679.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU936271.1, CA463205.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BU936271.1         4-11
            9-581               AK019807.1         2-574
            582-586             BX631095.1         4-8                 c
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.77 cM"
     gene            1..586
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /note="transmembrane protein 190"
                     /db_xref="GeneID:78052"
                     /db_xref="MGI:MGI:1925302"
     exon            1..101
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..544
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /codon_start=1
                     /product="transmembrane protein 190 precursor"
                     /protein_id="NP_084304.1"
                     /db_xref="CCDS:CCDS51976.1"
                     /db_xref="GeneID:78052"
                     /db_xref="MGI:MGI:1925302"
                     /translation="MVGSGISALGLLLLMQGSVDANGIQGFFYPWSCEGDVWDRESCG
                     GQAAIENPNLCLRLRCCYRDGVCYHQRPDENMRRKHMWALGWTCGSLLFLITSICLFW
                     WARRQDMLHLPRFLHRKCSKLSKTVSSLSKDRRSANKSTTVLQSPGGEVETAAAVSGE
                     DTGGEE"
     exon            102..137
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            138..263
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            264..348
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            349..586
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      566..571
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /note="hexamer: AATACA"
     polyA_site      586
                     /gene="Tmem190"
                     /gene_synonym="4930572D21Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctaggtttc tttgcagagg ccccagaggt ctggggaggt aacatggtgg ggtctgggat
       61 ctcagctttg ggccttctcc tgctgatgca gggctcagta gatgcgaatg gaatccaggg
      121 atttttctac ccatggagtt gtgagggaga tgtgtgggac cgagagagct gtgggggtca
      181 ggcagcaatt gagaacccca acctctgcct acgcctgcgg tgctgctacc gggacggtgt
      241 gtgctatcat cagcggccag atgaaaatat gcggaggaag catatgtggg cactgggctg
      301 gacctgtggc agcctactct tcctgatcac cagtatctgt ctcttctggt gggccaggcg
      361 ccaagacatg ctgcacctac caaggtttct acatcggaaa tgtagtaaac tgtcaaagac
      421 agtctcctca ctgtctaagg accgacgatc ggccaacaag tcaactaccg ttctccaatc
      481 cccaggaggc gaagtagaaa ctgcagctgc agtttccggg gaggacacag gaggtgaaga
      541 atagggcaac cctggaggat cccttaatac agatatagca tataaa
//
