LOCUS       NM_146103               2830 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus transmembrane protein 185B (Tmem185b), mRNA.
ACCESSION   NM_146103 XM_973557
VERSION     NM_146103.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   2  (bases 1 to 2830)
  AUTHORS   Maurer,M.H., Grunewald,S., Gassler,N., Rossner,M., Propst,F.,
            Wurz,R., Weber,D., Kuner,T., Kuschinsky,W. and Schneider,A.
  TITLE     Cloning of a novel neuronally expressed orphan G-protein-coupled
            receptor which is up-regulated by erythropoietin, interacts with
            microtubule-associated protein 1b and colocalizes with the
            5-hydroxytryptamine 2a receptor
  JOURNAL   J Neurochem 91 (4), 1007-1017 (2004)
   PUBMED   15525354
  REMARK    GeneRIF: The mouse ee3 is an orphan G-protein-coupled receptor with
            potential connections to erythropoietin and 5HT2a receptor
            signalling. ee3_2, a similar gene, is also described, along with
            human orthologs.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132393.4.
            
            On May 27, 2011 this sequence version replaced NM_146103.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK031130.1, BC020408.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2830              AC132393.4         91948-94777
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 52.31 cM"
     gene            1..2830
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /note="transmembrane protein 185B"
                     /db_xref="GeneID:226351"
                     /db_xref="MGI:MGI:1917634"
     exon            1..2830
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..1410
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /note="ee3_2; erythropoietin-induced EST 3-2"
                     /codon_start=1
                     /product="transmembrane protein 185B"
                     /protein_id="NP_666215.1"
                     /db_xref="CCDS:CCDS69932.1"
                     /db_xref="GeneID:226351"
                     /db_xref="MGI:MGI:1917634"
                     /translation="MNPRGLFQDFNPSKFLIYACLLLFSVLLPLRLDGIIQWSYWAVF
                     APIWLWKLLVIVGASVGAGVWARNPRYRTEGEACVEFKAMLIAVGIHLLLLMFEILVC
                     DRVERGTHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRL
                     DRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLLFLRSLDVVAEQRRTHVTMAISWI
                     TIVVPLLIFEVLLVHRLDDHNTFSYISIFIPLWLSLLTLMATTFRRKGGNHWWFGIRR
                     DFCQFLLEVFPFLREYGNISYDLHHEDSEDAEDASVSEAPKIAPMFGKKARVVITQSP
                     GKYVPPPPKLNIDMPD"
     polyA_site      2073
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /note="major polyA site"
     regulatory      2098..2103
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /note="hexamer: ATTACA"
     polyA_site      2133
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
     regulatory      2609..2614
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2629
                     /gene="Tmem185b"
                     /gene_synonym="2500001K11Rik"
ORIGIN      
        1 tcctccagga agcgtcctcc gaaggtctcg gccagctcac aggcagcggg tctgcgggtc
       61 gccgagtccg cagcgcgcca ggtcccatcc gactccgcac gcaacgcggc gtcggcctcg
      121 tggctgcgaa atgaaggcag acggcgtgag catccactga agcctgagct acggggttgg
      181 ggcagtgtcc ccggcgtagg caccgtaccg ttcgcggcca gcgcacgctg tgccctcggc
      241 tcgcttccgg ccgggccacg tgactgctcg cacgtgttcc ggcccctcgg agctgcggtc
      301 tggagcctct aacacgcagc gggcggatgc ccatctagag gcagtacagc cttcgccatg
      361 aaccccaggg gcctgttcca ggacttcaac cccagtaagt tcctcattta tgcctgcttg
      421 ctactcttct ccgtgctgct gcccctgcgc ctggacggca tcatccagtg gagctactgg
      481 gcagtcttcg cccccatctg gctgtggaag ctcctggtca tcgtgggcgc ctcggtgggt
      541 gcgggcgtgt gggcccgcaa cccacgctac cgtacagagg gggaagcctg cgtggaattc
      601 aaagccatgc ttatcgccgt gggcatccac ctgctactac tcatgtttga gatactagtc
      661 tgcgacaggg tggagagggg cacccacttt tggctgctgg tcttcatgcc actcttcttc
      721 gtttcccctg tgtccgtggc cgcctgtgtc tggggcttcc gacacgacag gtctttggaa
      781 ctggagatcc tgtgctctgt caacatcctg cagttcatct tcatcgccct gaggctggac
      841 aggattatcc actggccgtg gctagtggtg ttcgtgcccc tgtggatcct catgtcattc
      901 ctctgcctgg tagttctcta ttacatcgtg tggtccctcc tattcctgcg gtccctggat
      961 gtggttgcag agcagcgaag aacacatgtg accatggcca tcagctggat caccattgtc
     1021 gtgcccctgc tcatttttga ggtcctgcta gttcacagac tggatgacca caatacgttc
     1081 tcttacattt ccattttcat cccgctttgg ctctcattac tgactttgat ggctacaacg
     1141 ttcaggcgga aagggggcaa tcattggtgg tttgggattc gcagggattt ctgtcagttt
     1201 ctactagaag tttttccgtt tttaagagaa tatggaaata tctcttacga tctccatcac
     1261 gaagacagtg aagatgctga agacgcatcg gtgtcagaag ctccgaaaat tgctccaatg
     1321 tttggaaaga aggcgcgggt agttataaca cagagccctg ggaaatatgt gcctccacct
     1381 cccaagttaa acattgatat gccagactaa actcacaggc tgggcctttc agtgaaataa
     1441 gaaccatata cccttgaatt ccactttgct tttttcttgt gttcatccag tcctggaatt
     1501 ggaaacaggt ccccctcatt ttacatccac actgagacag aagtctcttg cagtggtcat
     1561 tgtgtgccgt aggcagaagg gggaaactgt aggactgtgg gatgtgtaca taatgtgcaa
     1621 gagaacttgc tttccaggcc cacatcttgt gagctagcca aaggtggtaa atcgaattgt
     1681 ttctaggcct tcaaaagacc tgaaaactac atagctgttt gttttaaagt gctacttatg
     1741 cctaccaaaa gtattgttta aaaagtattt ttatacactg ctagtctaaa attgtatttt
     1801 agattgcacc cattgtgaca aaatggcaaa tgtaccaaat tgtcccctcc cactgttccc
     1861 taaacctcat tgttggtgtt tctagtgctc ctactgttca aatagttgtt ttctgtgggc
     1921 tttgcggaca caggtctcta gtattctaat agatgaattt tctaatggag tgaatctgca
     1981 tatattagta tttatatgaa tgttttagca gtgttatctg tgttgattgt agttcttggc
     2041 agtaatgtat tgtgttaaag tatttttttt taagtttctg tgtgaagata tgtatttatt
     2101 acaactatcc ttaaagactg aatgagatgc taatatgtcc ctgacccaga atcctgtccg
     2161 agtcttggga tgaaggtttg gtgtggtaga taacaagagt tctacacatt tttaaagttt
     2221 gtgatcgtgt ccccagagaa aagggacagc agcactcaga gaatatttga catgctccaa
     2281 tacggcccca ggccatgaac actgtcagtt aacaccctgg cttcttcctc atggatatta
     2341 gcatctcttg aggaacaacc aaaatatgcc acacacagtt tggccatttc taaggtctgt
     2401 cataatgtaa agcatttctg ttggaaggct gagcgtgacc aacagggaga ggtattagaa
     2461 gggctaacat agcccgccag taacaaggaa caaatgttta ggtattttta aagatgagta
     2521 tagtgtttct tcaggagcta gagtcacccc aggaaatcag aaccagagga caaagccaga
     2581 cctcagaata agggtctgac tgggaagaaa taaatacttg gaaatggaag ttaaagaaac
     2641 atggggtgct catcgctgag gagaagactg gggtggagcg gttactagct tactaaggat
     2701 tacctacacc aggctccatg tgtttaactg ccccattgct ctgggtgtga cacggtcctc
     2761 ttccatttga aggaaaagaa aacctggtgc tggagagaca gtaaagtatg ctgtgcaaac
     2821 atgacctgtg
//
