LOCUS       NM_172608               3388 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus transmembrane protein 184b (Tmem184b), transcript
            variant 1, mRNA.
ACCESSION   NM_172608 XM_128300
VERSION     NM_172608.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3388)
  AUTHORS   Wright,E.B., Larsen,E.G., Coloma-Roessle,C.M., Hart,H.R. and
            Bhattacharya,M.R.C.
  TITLE     Transmembrane protein 184B (TMEM184B) promotes expression of
            synaptic gene networks in the mouse hippocampus
  JOURNAL   BMC Genomics 24 (1), 559 (2023)
   PUBMED   37730546
  REMARK    GeneRIF: Transmembrane protein 184B (TMEM184B) promotes expression
            of synaptic gene networks in the mouse hippocampus.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3388)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 3388)
  AUTHORS   Bhattacharya,M.R., Geisler,S., Pittman,S.K., Doan,R.A., Weihl,C.C.,
            Milbrandt,J. and DiAntonio,A.
  TITLE     TMEM184b Promotes Axon Degeneration and Neuromuscular Junction
            Maintenance
  JOURNAL   J Neurosci 36 (17), 4681-4689 (2016)
   PUBMED   27122027
REFERENCE   5  (bases 1 to 3388)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 3388)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY275319.1, AK029129.1 and AA240987.1.
            
            On Mar 31, 2005 this sequence version replaced XM_128300.5.
            
            Transcript Variant: This variant (1) is the predominant transcript
            and encodes a 407aa isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158789.1, AK029129.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BY275319.1         2-24
            24-3127             AK029129.1         2-3105
            3128-3388           AA240987.1         166-426
FEATURES             Location/Qualifiers
     source          1..3388
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..3388
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /note="transmembrane protein 184b"
                     /db_xref="GeneID:223693"
                     /db_xref="MGI:MGI:2445179"
     exon            1..119
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            120..369
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            370..535
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            536..626
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            627..702
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            703..794
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            795..964
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1159
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..3361
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3307..3312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3328
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /note="major polyA site"
     regulatory      3339..3344
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /note="hexamer: AATATA"
     polyA_site      3361
                     /gene="Tmem184b"
                     /gene_synonym="2610507A11; 4732495E13Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgcgcaggc gcggcgcggc ggtacccggc ggggctcggg acgcgccagc ggcggccgag
       61 ataccgggct gcggcgccgc ctgctccgcc tgcagtctcc agcgccatgg gctcctgagg
      121 ccagcccgtc actcacggca cgagatcctc tcagggagcc tgctgctgct gggaaccatg
      181 acagtgaggg gggccgcgct ggccccagac ccagcgtcac ccacaaccac aacagcttca
      241 cctagcgtct ctgccacccc cgagggcagc cccacagcca tggagcaccc tgtgttcctg
      301 atgaccactg ccgcccaggc catctccggc ttctttgtgt ggacagctct gctcatcact
      361 tgccaccaga tctacatgca tctgcgctgc tacagccgtc ccaatgagca gcgccacatc
      421 gtgcgcatcc tcttcatcgt gcccatctac gccttcgact cctggctcag cctcctcttc
      481 ttcaccaatg accagtacta cgtgtacttc ggcaccgtcc gagactgcta tgaggccttt
      541 gtcatctata acttcctgag cttgtgctat gagtacctcg ggggagagag tgccatcatg
      601 tctgagatca gagggaaggc cattgagtcc agctgtatgt acggcacgtg ctgcctctgg
      661 ggaaagacct actccatcgg attcctgcgg ttctgtaaac aggccaccct gcagttctgt
      721 gtggtgaagc cactcatggc cgtcagcacc gttatactcc aggcctttgg caagtaccgg
      781 gacggagact ttgatgtcac cagtgggtac ctctacgtga ccatcatcta caacatctcc
      841 gtcagcctgg ccctatatgc gctcttcctc ttctactttg ccacaaggga gctgctcagc
      901 ccctacagcc ctgtcctcaa gttcttcatg gtcaagtccg tcatattcct ctccttctgg
      961 caaggcatgc tgctggccat cttagagaag tgcggggcca tccccaagat caactcagcg
     1021 cgagtgtcag tgggtgaggg caccgtggct gccggctacc aggacttcat catctgtgtg
     1081 gagatgttct tcgcggcctt ggccctgcgg catgccttca cctacaaggt ctacgctgac
     1141 aagagactgg acgctcaagg ccgctgcgcc cccatgaaga gcatctccag cagcctcaaa
     1201 gagaccatga acccacacga tattgtgcag gacgccatcc acaacttctc gccagcctac
     1261 cagcagtaca cgcagcagtc cactctggag cccgggccca cctggcgtgg cggcacgcac
     1321 agcctttccc gctcccacag ccttagtggt gcacgcgaca atgagaagac tctgctgctc
     1381 agctctgatg atgagttcta agtgtgggcc ctggagggga aggagaggtg cttcccccag
     1441 cccccagcca ggctggggag cagagcaacc agcacagcat ggctgctgcc cttttattta
     1501 ttggaccaga aactcgcata tcacttccag aggaacaggc ctcaggaata tttctccctg
     1561 gccagccctg cactagctgg ggcaggggca gaggacagcg gctgtagctg tcacatctct
     1621 gcgactcatc ctgtaccgtg tgttggccag aagctgcatc ctaagccccc tccccaacaa
     1681 gatatctgcc gagctgtcag gcccagccca ccctacaccg tgcaataccc agacccagcc
     1741 tggtctttcc ccaggccttt gcccgcttct ccctggtcac ccttgtccag tgtgagtttt
     1801 gtcacattct gggcaggtag agacgtgaat gctctgtgga ccctccccct ctcccaacct
     1861 aggcctgtct ggcatgctgc aaggaccaga gccagccccc aggagcctca gggcccactt
     1921 aggaaggatg ccttgtgcct atgggccctt tggtgacatg tggggctctg gatccttggg
     1981 tgtcctcact gtggccactc tgcctgctga ggacagccag aagcccacac tgccctctca
     2041 cttgggtcca gttcttgata gttgggggca gagcccccac actcccttat acttcctgac
     2101 tgtgccaggg cttgggttcc ccaccacctc ctcaatggag caaagactcc tgctaggccc
     2161 tggtctccct ggggtttatc cctcctgggt catgggaaaa gtcagtctcc acattacaga
     2221 tcacttccag agggaggctg gagggatggt catacagcgg ggccaaggta ggggtggtct
     2281 cagaccctcc tgggtcccct gaccatacag ggcctggtgg tctgctccat ctggcccctg
     2341 gcccatctct tctgtgcctt agtcacatat gaaagcccct ccccagttcc cgtctgctcc
     2401 aggcactcct cgttgagctg ctggcactca gggttccgca gcgctgggtt gggcatcctt
     2461 gggaccaccc accctctccc tggctccctc tacacgcaca tcccagagct gcctcccagg
     2521 gctgggatct cagaggtagg gtggcagggg cctggtaagc agaattcaag cagcacttgg
     2581 tcttggctcc agtagcctct tgaggtggag agtggtgggg agccctacct tgtagccttc
     2641 agtggatgct ctccccttgg tcacctctgg aacaaacagg ttccttccct ggggtccata
     2701 gggagggacc tcatggggct gtcacatcct agcaaccttc ttagcctcct tccttccttc
     2761 cacacggccc agaggccagc tcggccccac ccagagggcc tggccagctg ctcccaagcc
     2821 acccagggag gcagcagaca ggtgggagct cctggggcac ggccgtggga ttgcttccac
     2881 cagtgtgttt ctgagacttc tccttatctt ccaggccaaa gtatgttgct gcttcctgtc
     2941 tccactggtc cccacctacc ctggcacttg ccctgtgaca tgatgggtga ggctgtgggg
     3001 gaactcagtg gcaggaagct agtggtccct gggaacaggg gacaggaatc cgtacccaac
     3061 tgccccgttc tttcttccca ttctttcttc ctaggatgca taaactatct tgtctcattt
     3121 attttttaat tttttttcag atagagtagc tctttgtaca taaaaaaaat acttgaaaat
     3181 tgtatgatgt atgagaagac agagccccct agttttgtat tttgtcctgt gactgccatg
     3241 cgttccacca gaaagccgct ctattttggt ctctgtgata ttttaaatgc gtgacagaag
     3301 caagcaaata aagtcaggaa gaaatatata tatgagataa tatagattgt attgaaatct
     3361 caaaaaaaaa aaaaaaaaaa aaaaaaaa
//
