LOCUS       NM_020588               3169 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 183A (Tmem183a), transcript
            variant 1, mRNA.
ACCESSION   NM_020588
VERSION     NM_020588.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3169)
  AUTHORS   Thoren,L.A., Norgaard,G.A., Weischenfeldt,J., Waage,J.,
            Jakobsen,J.S., Damgaard,I., Bergstrom,F.C., Blom,A.M., Borup,R.,
            Bisgaard,H.C. and Porse,B.T.
  TITLE     UPF2 is a critical regulator of liver development, function and
            regeneration
  JOURNAL   PLoS One 5 (7), e11650 (2010)
   PUBMED   20657840
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3169)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 3169)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY142931.1, AK152852.1 and AK013009.1.
            
            On Jun 30, 2006 this sequence version replaced NM_020588.1.
            
            Transcript Variant: This variant (1) encodes the longer protein
            (isoform a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB041592.1, AK152852.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-304               BY142931.1         9-312
            305-3167            AK152852.1         245-3107
            3168-3169           AK013009.1         2025-2026
FEATURES             Location/Qualifiers
     source          1..3169
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 58.2 cM"
     gene            1..3169
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="transmembrane protein 183A"
                     /db_xref="GeneID:57439"
                     /db_xref="MGI:MGI:1914729"
     exon            1..238
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1257
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="isoform a is encoded by transcript variant 1;
                     transmembrane protein 183"
                     /codon_start=1
                     /product="transmembrane protein 183 isoform a"
                     /protein_id="NP_065613.1"
                     /db_xref="CCDS:CCDS35714.1"
                     /db_xref="GeneID:57439"
                     /db_xref="MGI:MGI:1914729"
                     /translation="MARGSGQLGGPHRDTVTMPKRGKRLKFRAHDACSGRVTVADYAN
                     SDPAVVRSGRVKKAVANAIQQEVKSLCGLEASQVPAEEALSGVGEPCDILDSSDEMDA
                     QEESTQERSVSRKKKSKRHKEDPDGTGEEYPMDIWLLLASYIRPEDIVNFSLICKNAW
                     TVTCTAAFWTRLYRRHYTLDASLPLRLRPESMEKLRCLRACVIRSLYHMYEPFAARIS
                     KNPAIPESTPSTLKNSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCMERLQP
                     PIQYQDVHTNPDQDCCLLQVTTLNFIFIPIVMGMIFTLFTINVSTDMRHHRVRLVFQD
                     SPVRGGQNLRSEQGVQVVLDPVHSVRLFDWWHPQYPFSLRA"
     exon            239..328
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            329..496
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            497..653
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            654..834
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            835..915
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1071
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..3169
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1713..1718
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="hexamer: AATAAA"
     polyA_site      1745
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="major polyA site"
     regulatory      3149..3154
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="hexamer: AATAAA"
     polyA_site      3169
                     /gene="Tmem183a"
                     /gene_synonym="1300007B12Rik; 1700020N19Rik; Tmem183"
                     /note="major polyA site"
ORIGIN      
        1 gtcggcaatc aacgggaccc agagccctcg ccgaagtcct cgcgatagcc gcggcctcgg
       61 tgcggggatg gccgcagagc cgggtggagg tgctctgcgg ctccgggagc cggctctcgg
      121 ggccgagaca tggcccgggg ctccggccag ctaggcgggc ctcatcggga caccgtcacc
      181 atgcccaaga gaggaaagcg gctcaagttc cgggcccacg acgcctgctc gggccgagtg
      241 accgtggcgg actatgccaa ctcggatccg gcggtggtga ggtctggacg ggtcaagaaa
      301 gccgtggcca acgctattca gcaggaagta aaatctcttt gtggcttgga agcgtcccag
      361 gttcctgccg aggaggctct ttccggggtg ggtgagccat gtgacatcct ggacagcagt
      421 gatgagatgg atgcccagga agaaagcact caggaaagat cagtctccag aaaaaagaag
      481 agcaagagac ataaagaaga cccggatggc actggagaag agtatcctat ggatatttgg
      541 ctgctgctgg cttcctatat ccgtcctgag gacattgtga atttttccct gatttgtaaa
      601 aatgcttgga ctgtcacttg cactgctgcc ttttggacca ggttgtaccg aaggcactac
      661 acgctggatg cgtctctgcc tttgcggctg cgaccagaat ccatggagaa gctgcgctgt
      721 ctccgggcat gtgtgatccg atctctgtat catatgtatg aaccatttgc tgctcgaatc
      781 tccaagaatc cagccattcc ggaaagcact cccagcacac tgaagaattc caaatgctta
      841 cttttctggt gcagaaagat tgttgggaac agacaagaac caatgtggga gttcaacttc
      901 aagttcaaaa aacagtcccc tagattaaag agcaagtgta tggaacggtt gcaaccgccc
      961 attcaatatc aagatgtcca taccaaccct gaccaggact gctgcctact gcaggtcacc
     1021 accctcaact tcatctttat tcctattgtc atggggatga tatttacctt gtttaccatt
     1081 aatgtgagta cagacatgcg gcatcatcga gtgagattgg tgttccagga ttctcctgtc
     1141 cgtggtggtc agaatctgcg tagtgaacag ggtgtgcaag tcgtcctgga cccggtgcac
     1201 agtgttcggc tctttgactg gtggcatccg cagtatccat tctccctgag agcatagttc
     1261 ctgcttcctg tccctcggga tagcttccag tctagtccat tagtaatcag attctgtttg
     1321 gaaggggcag ctgtattgtg tagctgatta gtgatgcaca ggctgtttgg gttcctgggg
     1381 ctcctgttac aggaggtgga aaggttgaat caagaggaaa accaactatg atttataaac
     1441 attttcatgt aaaatttgca tatttgaaag gagaaacctg gcctcatttt ctgtgttaaa
     1501 cctcaattgg tgctgttgag tttgttcttc gttcatttat ctcagcaaat ggatgatctt
     1561 tcgttagggg aaagttaaac tcttactctt catggaagaa cgtttttcct tacagattag
     1621 aggaactcag aggcttaaaa tggttgctcc aatgttgctg ctcctcaaat tcaagtgaat
     1681 atttttttct tttcccttta cccttctcca gaaataaagc aggtgacagg gttgtcagaa
     1741 tcttataaga ttgatttgtg catcttttaa aaaaaatgct ttttggatat ttattacatg
     1801 aatattgatt gttttgatga ttttgtattt tgggtttttg ttttattgca tgagacttaa
     1861 tagtgatggt aataattatg tgcccctggt actgttctaa gaactttata gattgtgtct
     1921 ctaatccttg tgtcttgcaa ggtagttgaa acccttccca ttttaaggtt gagaagctga
     1981 atcattgatt tacccaaggc cagaactgct ggtccatgca gagccaggat tctgacccct
     2041 gtcttttgct acacaacaac ttcaaaggcc agtttcattt ttcgtgtggt acttagtggt
     2101 acaaagagga ggcagagtgt gaggaaaaag taaaacaatg agttatttga atctttcaga
     2161 tagctatgca ttaactgaaa ggtaaggcag agtttaggaa aattgtgttt acattaaatt
     2221 gttaggcttt ataatgctaa aggtcatctt taaaaaatac attgcatgtt gaaagcagcc
     2281 ttcaaataga gcaattagtg gcttttctct gccctgtcct gtcctttgat atctttgttt
     2341 ttccttttta aatcatcctg tgtgcattca ggatcctggt cttcatacag agatgttgac
     2401 acccttctta gtcacagttc ttactgtcac tggcatgctc tgagaaaagg atgtgggtgg
     2461 ggttttgttt atttcttttg ctaagaagaa agtcttactg cttcctttcc cacctggatg
     2521 tggcaggaga tgctcattaa gacaatgctc tcctactcaa gacctggagt tcatcctgta
     2581 gcgctgcagt ccagcctccc tgccccacaa aaatagtcct ttggagacag ggtcttgctg
     2641 tgtagcccag gctggccttg cacttaatcc tcttacttta gctgcctgga gttgttgggt
     2701 gagtcaccag acaggacaaa gacagaaaat gttctttaaa cataaaaata ttgtggggtg
     2761 gatacttttg tgagctaaat tgctaaatga gtatgttggt ttttatcttt ccccacccca
     2821 tgctatttaa agaccattct taagcatctg tttaatgctg ctgctgacag cagccgtacc
     2881 cacactgagg ggcatgctgt cactggttga acagatagtg agcctgggtc aataaaaaga
     2941 accaccagaa tttgggtact taattaacaa agcaaacaaa aaccctagga cagtaagcct
     3001 ccacagatct ctgcagtcag aagctgccta gaggcagaag aaaagaagca cagagtctgg
     3061 agttccctga acaaaagatg ccatggagca ggggaagttg tccttgtgga ttgtgtgtct
     3121 cccatttagg tttaccctga gtgggtgaaa taaatgtggc ttaattgtt
//
