LOCUS       NM_001081198            1096 bp    mRNA    linear   ROD 01-JUL-2024
DEFINITION  Mus musculus transmembrane protein 182 (Tmem182), mRNA.
ACCESSION   NM_001081198 XM_355302
VERSION     NM_001081198.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Chen,G., Lin,Z., Peng,H., Zhang,S., Zhang,Z., Zhang,X., Nie,Q. and
            Luo,W.
  TITLE     The transmembrane protein TMEM182 promotes fat deposition and
            alters metabolomics and lipidomics
  JOURNAL   Int J Biol Macromol 259 (Pt 1), 129144 (2024)
   PUBMED   38181918
  REMARK    GeneRIF: The transmembrane protein TMEM182 promotes fat deposition
            and alters metabolomics and lipidomics.
REFERENCE   2  (bases 1 to 1096)
  AUTHORS   Luo,W., Lin,Z., Chen,J., Chen,G., Zhang,S., Liu,M., Li,H., He,D.,
            Liang,S., Luo,Q., Zhang,D., Nie,Q. and Zhang,X.
  TITLE     TMEM182 interacts with integrin beta 1 and regulates myoblast
            differentiation and muscle regeneration
  JOURNAL   J Cachexia Sarcopenia Muscle 12 (6), 1704-1723 (2021)
   PUBMED   34427057
  REMARK    GeneRIF: TMEM182 interacts with integrin beta 1 and regulates
            myoblast differentiation and muscle regeneration.
REFERENCE   3  (bases 1 to 1096)
  AUTHORS   Kuninger,D., Kuzmickas,R., Peng,B., Pintar,J.E. and Rotwein,P.
  TITLE     Gene discovery by microarray: identification of novel genes induced
            during growth factor-mediated muscle cell survival and
            differentiation
  JOURNAL   Genomics 84 (5), 876-889 (2004)
   PUBMED   15475267
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC154392.18.
            
            On Feb 6, 2007 this sequence version replaced XM_355302.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.152591.1, BC147440.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               AC154392.18        50410-50696         c
            288-387             AC154392.18        50099-50198         c
            388-486             AC154392.18        48577-48675         c
            487-624             AC154392.18        17862-17999         c
            625-1096            AC154392.18        1030-1501           c
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 20.01 cM"
     gene            1..1096
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /note="transmembrane protein 182"
                     /db_xref="GeneID:381339"
                     /db_xref="MGI:MGI:1923725"
     exon            1..287
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..845
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /codon_start=1
                     /product="transmembrane protein 182 precursor"
                     /protein_id="NP_001074667.1"
                     /db_xref="CCDS:CCDS35550.1"
                     /db_xref="GeneID:381339"
                     /db_xref="MGI:MGI:1923725"
                     /translation="MRLNVAVFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEQN
                     IENITFHHEGFFWRCWFSGVVEENNSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHN
                     STSYDSAIIYRGFWAVLLLLGVVAALTASFLIICAAPFSSHFLYKAGGGSYIASGVLF
                     SLVVILYVIWVQAVADMESYRALRMRDCWEFTPSILYGWSFFLAPAGVFFSLLAGLLF
                     LVVGRHIQIHH"
     exon            288..387
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            388..486
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            487..624
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            625..1096
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      924..929
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /note="hexamer: CATAAA"
     polyA_site      942
                     /gene="Tmem182"
                     /gene_synonym="2310079P10Rik"
                     /note="major polyA site"
ORIGIN      
        1 agggtggaaa tgagaagcca ccacagctcc agcgaggacc tgctccccag acctagccga
       61 gtcgagagtg gctttctttc ttcacttgtt gttattgagc agttgactct ttacagcttg
      121 ctccttcatt tggaaggcaa ccagtcgatt ggaaaatgag actaaacgtt gccgttttct
      181 ttggggctct cttcggagct ttgggggttt tgttgttttt ggtagccttt ggatcggatt
      241 attggcttct cgcgactgaa gtgggcaggt gttcaggtga acagaatata gagaacatca
      301 cttttcacca tgaaggcttt ttctggaggt gctggttcag tggcgttgtg gaggagaaca
      361 actccaacat ctggaagttc tggtacacca atcagccacc atccaagaac tgcacacacg
      421 cttacctgtc cccgtacccc ttcatgaggg gagagcacaa ctccacctcc tacgactccg
      481 caattattta ccgtggcttc tgggcagtcc tgctgctcct gggggtagtg gccgccttga
      541 ctgcaagctt tctgatcatc tgtgcagccc ccttttccag tcacttcctt tataaagctg
      601 gaggaggctc atacattgcc tcaggtgtcc tgttttccct ggtggtgata ctgtatgtca
      661 tctgggtcca ggcagtggct gacatggaaa gctacagagc cttgaggatg agagactgct
      721 gggaattcac cccttccatc ctgtacggct ggtcgttttt tctggccccc gctggcgtat
      781 tcttctctct gctcgctggg ctgctctttc tagttgttgg acggcatatc cagatacatc
      841 actaactttt gcctctagag ttttcaggag agatttcgaa gcaccacact cccccgtctg
      901 ttttgtgtta gcaatggtat tggcataaaa ttagtggatg tacattggag ttatttctta
      961 atgagtcatt taattgtgat ttctcctcac aaaggagatc ttttgacttt tcaagaaccc
     1021 aaagctgtct gggctggcaa tgaactagtt ctccagggag caggtagtgg atctatcata
     1081 cattttgaag taaacg
//
