LOCUS       NM_175106               3316 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus transmembrane protein 177 (Tmem177), mRNA.
ACCESSION   NM_175106
VERSION     NM_175106.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3316)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3316)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB578893.1 and BC094344.1.
            
            On Feb 1, 2019 this sequence version replaced NM_175106.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094344.1, SRR7974084.8821.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BB578893.1         2-16
            16-3316             BC094344.1         1-3301
FEATURES             Location/Qualifiers
     source          1..3316
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 52.53 cM"
     gene            1..3316
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /note="transmembrane protein 177"
                     /db_xref="GeneID:66343"
                     /db_xref="MGI:MGI:1913593"
     exon            1..51
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            52..3316
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..1194
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /codon_start=1
                     /product="transmembrane protein 177"
                     /protein_id="NP_780315.1"
                     /db_xref="CCDS:CCDS15228.1"
                     /db_xref="GeneID:66343"
                     /db_xref="MGI:MGI:1913593"
                     /translation="MAGPLWRAAAFIQRHRTSLLVGSCAGLFGVQISFHLFPDPIVQW
                     LYQYWPQGQPAPLSPHLWSLFQEVLKDIGVPSGHCYKPFTAFTFQPVSAGFPRLPAGA
                     VVGIPAIFLGGPVTNIEHSVIIHGQRVDWQSPAGTRLRDALTMSHNAQKFALAKEVVY
                     LESGVAALQTLPAPACLAGTWAISVGAKHALGLYGGPMSLRTAFNLVAIVVGYVAYTF
                     SKDSLTLALEGWLDRRTASLSAAYVQGGVEFYEKILSGNLALRSLLGRQGEKLYTPSG
                     NIVPRHWFRINHLPYTTRRDSLQQMWRATVSPGRF"
     regulatory      1474..1479
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1496
                     /gene="Tmem177"
                     /gene_synonym="2300008B03Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcgcctgctc agtccggcgc gggagcggcg tgttctaagg ttgctaccga gttgctctac
       61 acctggctgc caatgggaaa gctgattctg tgaagcctga ggtgtcggac tctggatgga
      121 acccgtactc tcagccacaa tgcagtgtca cttcagttag gaacattgtg gccccggagg
      181 ttgtttagcc cacaacctga cagaaccatc ggctgacttc tcttcttctt ggccagtcta
      241 tcagcagagg cagtactcat ggctggtcct ctgtggaggg ctgcagcctt tatacagaga
      301 cacagaacaa gcctattggt gggttcctgt gcaggcctgt ttggggttca aatctcattt
      361 cacctcttcc cagatcccat agtccagtgg ctctaccagt actggcctca gggccaacca
      421 gctcctcttt cccctcatct gtggagcctc ttccaagagg tgctaaagga cataggtgtc
      481 ccttcgggtc actgctacaa gccttttacc gccttcactt ttcagcctgt gagtgctgga
      541 ttcccacggt tgcctgctgg ggctgtggtg ggaatccctg ccatcttcct gggtggccct
      601 gtgaccaaca ttgaacactc tgtgatcata catgggcaaa gagtggattg gcaaagccca
      661 gcaggcacca ggctgagaga tgccctgacc atgtctcata atgcccagaa gtttgccttg
      721 gccaaggagg tggtatacct ggagagtggt gtggctgccc tacagaccct gccagcccca
      781 gcttgcctag caggaacatg ggcaataagt gtgggtgcca agcatgccct ggggctctac
      841 ggaggcccca tgagcttgcg aactgccttt aacttggtgg caatagtggt aggctatgta
      901 gcctatacct tttccaaaga ctctctcact cttgccctgg aaggctggct ggaccgccgc
      961 acggcctctc tgtctgcagc ctatgtccag ggtggagtgg aattctatga gaagattctg
     1021 tcaggaaact tagccctacg cagtcttttg ggcagacaag gagaaaagct gtatacacca
     1081 agtggaaaca ttgtccccag acactggttt cgcatcaacc atttgcccta caccacccgc
     1141 cgggactctc tacaacagat gtggagggca acagtcagcc caggccgctt ctgagaatcc
     1201 aggcaacagg gcagtcctgg cttgcatagg cactgcctcg tgatgaactt gagatgaatc
     1261 tcttagtgtg gttgcaccca cagcccaggg tcagaagagt gaccgtcttt ggagttaaac
     1321 aattcaactc tgtcctcgcc atgaatagac tctggctgag cgtgagtccc tatatgaatc
     1381 ttgagtcttg tttacctcaa ctatgaagtg gggaggactg attgtagggt tgtatgagat
     1441 tgtgagcctg agggcctggt agaacgcagc ataaataaac agggctttct tccctagtgg
     1501 tctctgaatt ccagtggact gtggaagtca aaccatgagt caccaccaga catgtttctg
     1561 atatatccac cctttctttc ttgcagtgga gaactgccct aatctaccag atagcatata
     1621 gctaatttat cccttgcctt gatccttgga caagagaccc tagcaggaca aggtgaggag
     1681 acttgtgatc acagagctag acctaacttg gccattcaca tcatcttctc cttggaaatt
     1741 ctctcttccc tgggcagtct tgaaggatac cagcctgggt ccagtgtaac tcagaggaaa
     1801 ggccacacac cataggaagg gtactctggt ggctgtggta ggctgaagaa tggcagggtg
     1861 ggataaccag tggcttctac tcagactttg tatgtggttt agagttgagt gcactgccag
     1921 ccacgggtcc tttcccctgg tcatggcagg ctgagctctt gaggacaagg gactctagag
     1981 cagaatacaa tatgggactg atacgtggat ggtgttctag ctttctcttc tgtagatgtg
     2041 ataaaaaaat actctgacca gaagcaactc tagtaggaga ggtttacact tctagatcat
     2101 atcctccaat ccatcttgga gggaagtcag aacaggaact caagtcagcc ctggtgtcag
     2161 ggacgatgaa agaatgctgc cttctggtaa ctcttaactc ccagtctctg ctcagctagc
     2221 tttttataca acccaatact acctgcctat ggatgctact atccatccat taatagtgaa
     2281 gataatcccc cacagacaca cagagaccag tcttcagttg aggctttccc ttctcaggac
     2341 tgtaggcttt gtcaagttga caaatctaac caggacagat ggataaagta gttactagat
     2401 ggatggctct ccatccaggc tgacaacact ctacatccct cagtcactgc tgttgctgta
     2461 tgctgctagc taagggccaa aagtccacat caacacccac atggaaaagt atggacaccg
     2521 tggctccatc ttcttggccc ttaacactct aacactacac tatctactct taatcttgcg
     2581 aggaaccaag atggtggcag caggcccctc aatttatttg ctcaagtgct agggtttaaa
     2641 tatggaagct gtgtccccat tgtggcagtg ttgaaagtag ggaagccttt gagaggtggg
     2701 gcccagtggg aggtgatgag gccctttggg gtatcatctt caggaaggat ttgtgttggc
     2761 cttgcacagt gagctctggc aggcacaagt aactaaagct ttggtttact ttagtttttg
     2821 agatgaggtc tccctgtgtt gcccttgcca gctcagcctt ctgagtagct gttgctgcag
     2881 atgaaccacc ataccaagca cagttgttag aataagagca agaccagtgc agagtccaca
     2941 ctgtggtata catctggaat tgcagcattt tgggcaggag gattattagt ttgaggccag
     3001 cctatgctac acagtgaaac cctgtcttag aataataaac atgccatggt gcctcacaca
     3061 tgtgaacccc aacacttggt aggttgaagt ggttagaggt taacatgggt tacgtagtgg
     3121 tgaattctag gcaagactga cctaggccaa aaccctatcc aaagagcaag tccttccccc
     3181 atggcttccc gatattgtac cctcttccat gacaccttct tcaaggtgtc accagagatg
     3241 agcatgaaga agaaggtgat attttcctga acctccagaa ttatgagcta aataaacctc
     3301 ttaaaaaaaa aaaaaa
//
